PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
CBL	7	HCK	5	affinity chromatography technology, enzymatic study, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, unspecified method	Howlett CJ (2002), Howlett CJ (1999), Howlett CJ (1999), Howlett CJ (1999), Howlett CJ (1999), Anderson SM (1997), Liu BA (2012)	7
UBA2	0	SAE1	0	two hybrid, affinity chromatography technology, enzymatic study, pull down, pull down, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Ewing RM (2007), Gong L (1999), Desterro JM (1999), Okuma T (1999), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	10
SRC	2	FYN	1	unspecified method, affinity chromatography technology, affinity chromatography technology	Pirozzi G (1997), Chen Y (2009), Huttlin EL (2017)	3
CBL	7	NCK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Erdreich-Epstein A (1999), Miyoshi-Akiyama T (2001), Izadi KD (1998), Izadi KD (1998), Wunderlich L (1999), Shishido T (2000), Okabe S (2006), Adler CE (2000), Adler CE (2000), Buvall L (2013), Buvall L (2013), Buvall L (2013), Buvall L (2013)	13
SRC	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Burnham MR (1999), Song JJ (2010), Liu W (2010), Chen TC (2014)	4
EGFR	5	CRKL	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2008), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
WAS	0	KDM4A	3	affinity chromatography technology	Taylor MD (2010)	1
PACSIN2	0	WIPF1	0	affinity chromatography technology	Linkermann A (2009)	1
SRC	2	WAS	0	affinity chromatography technology, pull down, pull down	Banin S (1996), Banin S (1996), Finan PM (1996)	3
WAS	0	ABI3	1	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
JMJD6	1	UBE2I	0	biochemical	Kristensen AR (2012)	1
SORBS2	2	CBL	7	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Haglund K (2004), Haglund K (2004), Soubeyran P (2003), Soubeyran P (2003), Soubeyran P (2003), Soubeyran P (2003)	6
WAS	0	RANBP2	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Sarkar K (2015), Sarkar K (2015), Sarkar K (2015), Sarkar K (2015)	4
TRIP10	1	WAS	0	two hybrid, pull down, affinity chromatography technology, two hybrid	Tian L (2000), Tian L (2000), Tian L (2000), Yu H (2011)	4
PLCG1	6	WAS	0	pull down, pull down	Banin S (1996), Finan PM (1996)	2
CDC42	3	WIPF1	0	pull down	Martinez-Quiles N (2001)	1
ITSN1	5	PACSIN3	2	two hybrid	Wong KA (2012)	1
WBP4	0	TCERG1	3	pull down	Ingham RJ (2005)	1
RGS14	2	WAS	0	two hybrid	Wang J (2011)	1
LCK	0	PIK3R1	6	pull down	Kapeller R (1994)	1
NCK2	2	EGFR	5	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Chen M (1998), Braverman LE (1999), Tu Y (1998), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	6
PACSIN3	2	WIPF1	0	affinity chromatography technology	Linkermann A (2009)	1
APBB1	3	EGFR	5	unspecified method	Jones RB (2006)	1
SRC	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Olayioye MA (1999), Keely SJ (2000), Sato K (2000), Lee CW (2007), Jaganathan S (2011), Jaganathan S (2011), Lee IT (2010), Hitosugi T (2007), Chang CC (2012), Chang CC (2012), Tung WH (2011), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Yao Z (2017)	15
CSNK2A1	15	WAS	0	enzymatic study	Cory GO (2003)	1
PACSIN2	0	PACSIN1	0	two hybrid, two hybrid, pull down, pull down, two hybrid, two hybrid, two hybrid, affinity chromatography technology	Rual JF (2005), Modregger J (2000), Modregger J (2000), Modregger J (2000), Modregger J (2000), Bandyopadhyay S (2010), Rolland T (2014), Huttlin EL (2017)	8
WAS	0	VASP	0	pull down	Castellano F (2001)	1
PIK3R1	6	WAS	0	affinity chromatography technology, pull down	Banin S (1996), Banin S (1996)	2
GRB2	2	PIK3R1	6	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Saleem A (1995), Saleem A (1995), Wang J (1995), Wang J (1995), Wang J (1995), Bandyopadhyay S (2010), Takahashi Y (1999), Gelkop S (2001), Jain SK (1997), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Cerboni C (1998), Bisson N (2011), Bisson N (2011), Weinger JG (2008), Weinger JG (2008), Weinger JG (2008)	18
PACSIN1	0	GAS7	0	two hybrid	Bandyopadhyay S (2010)	1
BTK	1	CBL	7	pull down, x-ray crystallography, unspecified method, affinity chromatography technology	Cory GO (1995), Tzeng SR (2000), Patel HV (1997), Morrogh LM (1999)	4
FYN	1	FYB1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	da Silva AJ (1993), da Silva AJ (1993), Marie-Cardine A (1998), Marie-Cardine A (1999), da Silva AJ (1997), da Silva AJ (1997), Grossmann A (2015)	7
VASP	0	ARPC3	0	affinity chromatography technology	Boldt K (2016)	1
WAS	0	ARPC4	0	affinity chromatography technology	Cory GO (2003)	1
BTK	1	HCK	5	pull down	Cheng G (1994)	1
GRB2	2	BTK	1	two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Brehme M (2009)	2
NCK2	2	TNK2	7	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GRB2	2	TEC	2	affinity chromatography technology	Bisson N (2011)	1
ITSN2	7	WIPF2	1	two hybrid	Wong KA (2012)	1
FYB1	0	LCP2	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	da Silva AJ (1997), da Silva AJ (1997), da Silva AJ (1997), Grossmann A (2015), Xiong Y (2017)	5
RANBP2	9	UBA2	0	affinity chromatography technology	Sarkar K (2015)	1
EGFR	5	ITSN2	7	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
LCK	0	WAS	0	affinity chromatography technology, enzymatic study	Nervi S (2005), Torres E (2006)	2
EGFR	5	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ettenberg SA (1999), Tvorogov D (2002), Pennock S (2008), Umebayashi K (2008), Ng C (2008), Ng C (2008), Povlsen GK (2008), Khan EM (2008), Su X (2007), Shtiegman K (2007), Han W (2006), Visser GD (2005), Tsacoumangos A (2005), Prasad NK (2005), Gur G (2004), Kowanetz K (2004), Feshchenko EA (2004), Wu WJ (2003), Schmidt MH (2003), Bao J (2003), Rubin C (2003), Waterman H (1999), Bonaccorsi L (2007), Dey N (2011), Miraoui H (2010), Guo HB (2009), Tong J (2009), Tong J (2009), Sun Q (2010), Sanada F (2009), Rafiq K (2011), Ravid T (2004), Ravid T (2004), Duan L (2011), Duan L (2011), Haglund K (2005), Oksvold MP (2003), Oksvold MP (2003), Gui A (2012), Yang S (2006), de Melker AA (2004), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Raguz J (2007), de Melker AA (2004), Thien CB (2001), Kassenbrock CK (2004), Tarcic G (2009), Schroeder B (2012), Adachi S (2009), Shen F (2007), Mitsushima M (2006), Choi JH (2003), Burke P (2001), Tanaka S (1995), Meisner H (1995), Meisner H (1995), Kumar EA (2012), Tong J (2008), Dou H (2012), Levkowitz G (1999), Levkowitz G (1999), Bode AM (2009), Thomas C (2012), Meijer IM (2013), Chang CC (2012), Chang CC (2012), Smith CJ (2013), Gan Y (2010), Scott RP (2005), Fukazawa T (1996), Fukazawa T (1996), Fukazawa T (1996), Wang L (2013), Hong SY (2013), Sigismund S (2013), Sigismund S (2013), Sigismund S (2013), Meisner H (1997), Odintsova E (2013), Kondratov KA (2010), He Z (2014), Tong J (2014), Balaji K (2012), Kiuchi T (2014), Zhang B (2005), Waterman H (1999), Ha Thi HT (2015), Yao S (2015), Kortuem F (2015), Igloi Z (2015), Song F (2016), Song F (2016), Lin TY (2017), Conte A (2017)	96
CBL	7	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017)	83
RHOJ	0	WAS	0	two hybrid	Vignal E (2000)	1
HCK	5	WIPF1	0	pull down	Scott MP (2002)	1
CBLB	3	LCK	0	affinity chromatography technology	Kumar S (2011)	1
PACSIN3	2	WAS	0	affinity chromatography technology	Linkermann A (2009)	1
ITK	7	CBL	7	pull down	Bunnell SC (1996)	1
EGFR	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique	Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014)	6
WAS	0	NCK2	2	affinity chromatography technology, two hybrid	Buvall L (2013), Rolland T (2014)	2
ITSN1	5	FCHSD2	3	two hybrid	Wong KA (2012)	1
WAS	0	RAC1	7	pull down	Kolluri R (1996)	1
CBL	7	PLCG1	6	far western blotting, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique	Tvorogov D (2002), Tvorogov D (2002), Tvorogov D (2002), Graham LJ (1998), Singh AJ (2007), Rellahan BL (2003), Rellahan BL (2003), Okabe S (2006), Choi JH (2003), Choi JH (2003), Braiman A (2006), Braiman A (2006), Braiman A (2006), Chen TC (2014)	14
WAS	0	SAE1	0	affinity chromatography technology	Sarkar K (2015)	1
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
ITSN1	5	ITSN2	7	protein complementation assay	Wong KA (2012)	1
FGR	1	CBL	7	affinity chromatography technology	Melander F (2003)	1
FNBP1	0	WAS	0	affinity chromatography technology, affinity chromatography technology	Linkermann A (2009), Tsujita K (2006)	2
PACSIN2	0	PACSIN3	2	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Modregger J (2000), Modregger J (2000), Modregger J (2000), Huttlin EL (2015), Huttlin EL (2017)	5
GRB2	2	VASP	0	affinity chromatography technology	Brehme M (2009)	1
TCERG1	3	WIPF2	1	pull down	Ingham RJ (2005)	1
EGFR	5	SORBS2	2	protein complementation assay	Deribe YL (2009)	1
CBL	7	FYB1	0	affinity chromatography technology	Okabe S (2006)	1
NCK2	2	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Buvall L (2013), Buvall L (2013), Huttlin EL (2015), Huttlin EL (2017)	4
CRKL	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down	Gesbert F (1998), Gelkop S (2001), Ren SY (2005)	3
GRB2	2	WAS	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Banin S (1996), She HY (1997), She HY (1997), She HY (1997)	4
CSNK2A1	15	RELA	1	affinity chromatography technology, enzymatic study	Wang D (2000), Wang D (2000)	2
RAC1	7	LRPPRC	7	affinity chromatography technology	Boldt K (2016)	1
ITK	7	WAS	0	pull down, pull down	Cory GO (1996), Bunnell SC (1996)	2
LCP2	0	NCK1	0	affinity chromatography technology, pull down, affinity chromatography technology	Shim EK (2004), Wunderlich L (1999), de Castro RO (2012)	3
NCK1	0	PIK3R1	6	affinity chromatography technology	Gelkop S (2001)	1
APBB1	3	WAS	0	pull down	Ingham RJ (2005)	1
ITSN2	7	FCHSD2	3	two hybrid	Wong KA (2012)	1
ITSN1	5	PIK3R1	6	two hybrid	Wong KA (2012)	1
BAIAP2L1	1	WAS	0	pull down	Aitio O (2012)	1
NCK1	0	GRB2	2	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
ITSN1	5	CDC42	3	affinity chromatography technology, pull down, x-ray crystallography	Hussain NK (2001), Hussain NK (2001), Snyder JT (2002)	3
ARPC3	0	ARPC4	0	two hybrid, biochemical, pull down, biochemical, biochemical	Zhao X (2001), Havugimana PC (2012), Liu SL (2012), Kristensen AR (2012), Wan C (2015)	5
ITK	7	PLCG1	6	pull down, affinity chromatography technology, enzymatic study	Perez-Villar JJ (1999), Perez-Villar JJ (1999), Hao S (2002)	3
WAS	0	CBLB	3	affinity chromatography technology	Watanabe Y (2013)	1
VASP	0	ABI3	1	two hybrid	Rolland T (2014)	1
NCK2	2	NCK1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
23380	0	WAS	0	affinity chromatography technology	Linkermann A (2009)	1
UBE2I	0	UBA2	0	affinity chromatography technology, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, biochemical, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Knipscheer P (2008), Tatham MH (2003), Tatham MH (2003), Huang DT (2009), Gilbreth RN (2011), Okuma T (1999), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	10
CRKL	1	WAS	0	affinity chromatography technology, pull down	Oda A (2001), Oda A (2001)	2
EGFR	5	TNK2	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Lin Q (2010), Pao-Chun L (2009), Shen F (2007), Howlin J (2008), Howlin J (2008), Tong J (2008), Jones S (2014), Jones S (2014), Chua BT (2010)	9
WAS	0	NCK1	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Krause M (2000), Okabe S (2002), Rivero-Lezcano OM (1995), Rivero-Lezcano OM (1995), Buvall L (2013)	5
WAS	0	JMJD6	1	affinity chromatography technology	Taylor MD (2010)	1
CBL	7	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kassenbrock CK (2002), Rafiq K (2011), Rellahan BL (2003), Vantler M (2006), Shishido T (2000), Shishido T (2000), Song JJ (2010), Sanjay A (2006), Sanjay A (2006), Tanaka S (1995), Tanaka S (1995), Tanaka S (1995), Szymkiewicz I (2004), Hashimoto S (2006)	14
WAS	0	APPBP2	3	two hybrid	Rolland T (2014)	1
CDC42	3	CBL	7	affinity chromatography technology, pull down, affinity chromatography technology	Wu WJ (2003), Wu WJ (2003), Simmons A (2005)	3
PSTPIP1	3	WIPF1	0	affinity chromatography technology	Linkermann A (2009)	1
WAS	0	UBA2	0	affinity chromatography technology, affinity chromatography technology	Sarkar K (2015), Sarkar K (2015)	2
TEC	2	WAS	0	pull down	Cory GO (1996)	1
PACSIN2	0	WAS	0	affinity chromatography technology	Linkermann A (2009)	1
ITK	7	SRC	2	pull down	Bunnell SC (2000)	1
CBL	7	CBLB	3	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Rorsman C (2016)	2
FYN	1	CBLB	3	two hybrid	Grossmann A (2015)	1
APBB1	3	VASP	0	pull down	Ingham RJ (2005)	1
WIPF1	0	NCK1	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Anton IM (1998), Anton IM (1998), Hein MY (2015)	3
EGFR	5	FGR	1	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
FYN	1	CBL	7	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Taher TE (2002), Deckert M (1998), Deckert M (1998), Deckert M (1998), Ghosh AK (2004), Rellahan BL (2003), Boussiotis VA (1997), Andoniou CE (2000), Shishido T (2000), Okabe S (2006), Kaabeche K (2004), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tanaka S (1995), Reedquist KA (1996), Grossmann AH (2004), Panchamoorthy G (1996), Fukazawa T (1995), Fukazawa T (1995), Fukazawa T (1995), Nishio H (2002), Anderson SM (1997), Fukazawa T (1996), Grossmann A (2015)	27
WAS	0	TNK2	7	affinity chromatography technology, affinity chromatography technology, enzymatic study	Yokoyama N (2005), Yokoyama N (2005), Yokoyama N (2005)	3
LRPPRC	7	WAS	0	affinity chromatography technology	Hein MY (2015)	1
CBLB	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Ettenberg SA (1999), Lavagna-Sevenier C (1998), Lavagna-Sevenier C (1998), Elly C (1999), Bandyopadhyay S (2010), Vinayagam A (2011), Bisson N (2011), Blagoev B (2003), Rolland T (2014), Huttlin EL (2017)	10
LCP2	0	NCK2	2	two hybrid	Rolland T (2014)	1
CBLB	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavagna-Sevenier C (1998), Elly C (1999), Elly C (1999), Alcazar I (2009), Fang D (2001)	5
TNK2	7	CRKL	1	affinity chromatography technology	Mahendrarajah N (2017)	1
EGFR	5	PLCG1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tvorogov D (2002), Bedrin MS (1997), Crovello CS (1998), Choi JH (2003), Jones RB (2006), Tong J (2014), Egan JE (2002), Wu D (2009), Wu D (2009)	9
WAS	0	RELA	1	affinity chromatography technology	Sarkar K (2015)	1
GAS7	0	WAS	0	pull down, affinity chromatography technology, affinity chromatography technology	Ingham RJ (2005), Tseng RC (2015), Tseng RC (2015)	3
UBE2I	0	SAE1	0	affinity chromatography technology, enzymatic study, pull down, enzymatic study, biochemical, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Tatham MH (2003), Tatham MH (2003), Huang DT (2009), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	7
NCK2	2	WIPF1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
WAS	0	UBE2I	0	affinity chromatography technology, affinity chromatography technology	Sarkar K (2015), Sarkar K (2015)	2
FYB1	0	VASP	0	affinity chromatography technology	Krause M (2000)	1
WAS	0	LCP2	0	affinity chromatography technology	Krause M (2000)	1
APBB1	3	WIPF2	1	pull down	Ingham RJ (2005)	1
ARPC2	1	ARPC4	0	two hybrid, biochemical, biochemical, biochemical	Zhao X (2001), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	4
HCK	5	SRC	2	affinity chromatography technology	Howlett CJ (2002)	1
WAS	0	ARPC2	1	pull down	Huefner K (2002)	1
WAS	0	ITSN2	7	two hybrid, affinity chromatography technology, pull down, two hybrid	McGavin MK (2001), McGavin MK (2001), McGavin MK (2001), Wong KA (2012)	4
WAS	0	WIPF1	0	two hybrid, affinity chromatography technology, pull down, two hybrid, two hybrid, two hybrid	Ramesh N (1997), Ramesh N (1997), Ramesh N (1997), Anton IM (1998), Wang J (2011), Rolland T (2014)	6
GRB2	2	TCERG1	3	two hybrid	Bandyopadhyay S (2010)	1
PRPF40A	5	WAS	0	pull down	Ingham RJ (2005)	1
ITSN1	5	WAS	0	affinity chromatography technology, affinity chromatography technology	Tsyba L (2008), Wang JB (2005)	2
TRIP10	1	RHOJ	0	two hybrid	Rolland T (2014)	1
LCK	0	CBL	7	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Rao N (2002), Tsygankov AY (1996), Reedquist KA (1996), Nervi S (2005)	4
KDM6B	16	RBBP5	3	affinity chromatography technology	De Santa F (2007)	1
FYN	1	TNK2	7	affinity chromatography technology, pull down	Linseman DA (2001), Linseman DA (2001)	2
GRB2	2	ABI3	1	two hybrid	Rolland T (2014)	1
GRB2	2	LCP2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, unspecified method, affinity chromatography technology, two hybrid	Lewitzky M (2001), Robinson A (1996), Erdreich-Epstein A (1999), Hendricks-Taylor LR (1997), Asada H (1999), Bandyopadhyay S (2010), Chu J (1998), Berry DM (2002), Brehme M (2009), Rolland T (2014)	10
WAS	0	RBBP5	3	affinity chromatography technology	Taylor MD (2010)	1
TNK2	7	CDC42	3	affinity chromatography technology, two hybrid, affinity chromatography technology, x-ray crystallography, pull down, pull down, pull down, pull down, two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down	Kato-Stankiewicz J (2001), Bandyopadhyay S (2010), Lin Q (2010), Mott HR (1999), Mott HR (1999), Gu Y (2004), Gu Y (2004), Owen D (2000), Govind S (2001), Jones S (2014), Jones S (2014), Urena JM (2005), Urena JM (2005), Tetley GJN (2017), Tetley GJN (2017)	15
EGFR	5	HCK	5	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
TNK2	7	LCP2	0	affinity chromatography technology, affinity chromatography technology, imaging technique	Thaker YR (2017), Thaker YR (2017), Thaker YR (2017)	3
WAS	0	WIPF2	1	affinity chromatography technology, two hybrid	Aspenstroem P (2002), Wang J (2011)	2
TNK2	7	HCK	5	pull down, pull down	Chan W (2011), Yokoyama N (2003)	2
WAS	0	KDM6B	16	affinity chromatography technology	Taylor MD (2010)	1
NCK2	2	SORBS2	2	two hybrid	Rolland T (2014)	1
CBL	7	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Gesbert F (1998), Gesbert F (1998), Zhang S (1999), Dufour C (2008), Feshchenko EA (2004), Kassenbrock CK (2002), Fang D (2001), Valiya Veettil M (2011), Miao H (2002), Miao H (2002), Ueno H (1998), Gelkop S (2001), Wang Y (1999), Saci A (2000), Matsuo T (1996), Matsuo T (1996), Jackson JG (2000), Meisner H (1995), Saci A (1999), Saci A (1999), Beckwith M (1996), Beckwith M (1996), Song JJ (2010), Hartley D (1996), Finkelstein LD (2000), Ren SY (2005), Hunter S (1997), Hunter S (1997), Jain SK (1997), Jain SK (1997), Swaminathan G (2007), van Leeuwen JE (1999), Ren SY (2005), Ren SY (2005), Alcazar I (2009), Liu YC (1997), Matsuo T (1996), Matsuo T (1996), Lottin-Divoux S (2006), Kitanaka A (1996), Liu YC (1997), Grossmann AH (2004), Panchamoorthy G (1996), Panchamoorthy G (1996), Chernock RD (2001), Chernock RD (2001), Fukazawa T (1995), Fukazawa T (1995), Brehme M (2009), Hakak Y (2000), Hakak Y (2000), Fukazawa T (1995), Liu Y (1999), Cerboni C (1998), Cerboni C (1998), Momose H (2003), Fukazawa T (1996), Fukazawa T (1996), Bulut GB (2013), Bulut GB (2013), Grossmann A (2015)	61
ITK	7	FYN	1	pull down, pull down	Bunnell SC (2000), Bunnell SC (1996)	2
PLCG1	6	SRC	2	affinity chromatography technology	Dhar A (1994)	1
FYB1	0	NCK2	2	two hybrid	Grossmann A (2015)	1
TNK2	7	GRB2	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Satoh T (1996), Kato-Stankiewicz J (2001), Bandyopadhyay S (2010), Lin Q (2010), Lin Q (2012), Yeow-Fong L (2005), Chan W (2011), Yokoyama N (2003), Huttlin EL (2017), Mahendrarajah N (2017)	10
ARPC3	0	WAS	0	two hybrid, affinity chromatography technology, pull down	Machesky LM (1999), Cory GO (2003), Liu SL (2012)	3
ITSN2	7	WIPF1	0	two hybrid	Wong KA (2012)	1
PACSIN2	0	WIPF2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SRC	2	TNK2	7	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down	Chan W (2009), Modzelewska K (2006), Chan W (2011), Chan W (2011), Chan W (2011), Yokoyama N (2003)	6
PACSIN1	0	WIPF1	0	affinity chromatography technology	Linkermann A (2009)	1
TRIP10	1	CDC42	3	two hybrid, pull down, pull down	Aspenstroem P (1997), Tian L (2000), Aspenstroem P (1997)	3
LCP2	0	ITK	7	affinity chromatography technology, pull down, enzymatic study	Shim EK (2004), Bunnell SC (2000), Kim KS (2002)	3
WAS	0	EGFR	5	affinity chromatography technology, affinity chromatography technology	She HY (1997), She HY (1997)	2
SRC	2	GRB2	2	affinity chromatography technology, affinity chromatography technology	Wan KF (2003), Saci A (2002)	2
CBL	7	ITSN1	5	far western blotting, two hybrid, affinity chromatography technology, affinity chromatography technology	Martin NP (2006), Thalappilly S (2008), Dergai M (2011), Tsyba L (2008)	4
DVL2	5	CSNK2A1	15	affinity chromatography technology	Song DH (2000)	1
GRB2	2	CDC42	3	two hybrid	Vinayagam A (2011)	1
WBP4	0	WIPF1	0	pull down	Ingham RJ (2005)	1
PSTPIP1	3	WAS	0	affinity chromatography technology, pull down, affinity chromatography technology	Wu Y (1998), Wu Y (1998), Linkermann A (2009)	3
ITSN1	5	CBLB	3	affinity chromatography technology	Tsyba L (2008)	1
PRPF40A	5	VASP	0	pull down	Ingham RJ (2005)	1
NCK1	0	WIPF2	1	affinity chromatography technology	Hein MY (2015)	1
LCP2	0	PLCG1	6	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Yablonski D (2001), Yablonski D (2001), Braiman A (2006), Braiman A (2006), Braiman A (2006)	5
ARPC2	1	ARPC3	0	imaging technique, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Welch MD (1997), Havugimana PC (2012), Liu SL (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	7
NCK1	0	EGFR	5	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay	Tang J (1997), Li W (1992), Braverman LE (1999), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	6
EGFR	5	CBLB	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Schulze WX (2006), Ettenberg SA (1999), Davies GC (2006), Davies GC (2006), Tong J (2009), Ettenberg SA (2001), Tong J (2008), Levkowitz G (1999), Tong J (2014)	9
FYN	1	PIK3R1	6	pull down	Kapeller R (1994)	1
UBE2I	0	TCERG1	3	enzymatic study	Gocke CB (2005)	1
GRB2	2	WIPF2	1	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Bisson N (2011), Wang J (2011), Huttlin EL (2017)	4
CDC42	3	WAS	0	pull down, pull down, pull down, pull down, two hybrid, pull down, pull down, affinity chromatography technology, pull down	Tian L (2000), Kim AS (2000), Kolluri R (1996), Symons M (1996), Bandyopadhyay S (2010), Mott HR (1999), Owen D (2000), Edlund S (2004), Tetley GJN (2017)	9
TNK2	7	NCK1	0	pull down, affinity chromatography technology	Chan W (2011), Hein MY (2015)	2
FGR	1	WAS	0	affinity chromatography technology, pull down, pull down, pull down	Banin S (1996), Banin S (1996), Finan PM (1996), Rivero-Lezcano OM (1995)	4
PACSIN1	0	WAS	0	affinity chromatography technology	Linkermann A (2009)	1
WAS	0	SORBS2	2	two hybrid	Rolland T (2014)	1
EGFR	5	LCP2	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
EGFR	5	ITK	7	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
PRPF40A	5	UBE2I	0	two hybrid	Colland F (2004)	1
WBP4	0	WAS	0	pull down	Ingham RJ (2005)	1
EGFR	5	LRPPRC	7	affinity chromatography technology	Tong J (2014)	1
DVL2	5	WAS	0	two hybrid	Yu H (2011)	1
ITSN1	5	FNBP1	0	two hybrid	Wong KA (2012)	1
ITSN2	7	CBL	7	two hybrid	Wong KA (2012)	1
CBLB	3	NCK2	2	two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Rual JF (2005), Rolland T (2014), Huttlin EL (2015), Yu H (2011), Huttlin EL (2017)	5
HCK	5	WAS	0	pull down	Scott MP (2002)	1
PLCG1	6	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Pei Z (1997), Pei Z (1997), Nel AE (1995), Scholler JK (2000), Choi JH (2005), Choi JH (2005)	6
BTK	1	WAS	0	pull down, affinity chromatography technology	Cory GO (1996), Morrogh LM (1999)	2
PRPF40A	5	TCERG1	3	biochemical	Havugimana PC (2012)	1
SRC	2	CSNK2A1	15	affinity chromatography technology	Liang K (2010)	1
TCERG1	3	WAS	0	pull down	Ingham RJ (2005)	1
LCP2	0	PIK3R1	6	two hybrid, affinity chromatography technology	Shim EK (2004), Shim EK (2004)	2
PACSIN1	0	PACSIN3	2	two hybrid, pull down, pull down, two hybrid, two hybrid, affinity chromatography technology	Modregger J (2000), Modregger J (2000), Modregger J (2000), Modregger J (2000), Rolland T (2014), Huttlin EL (2017)	6
APBB1	3	WIPF1	0	pull down	Ingham RJ (2005)	1
RAC1	7	TEC	2	genetic interference	Kline JB (2001)	1
EGFR	5	UBA2	0	affinity chromatography technology	Tong J (2014)	1
PRPF40A	5	WIPF1	0	pull down	Ingham RJ (2005)	1
CBL	7	LCP2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park RK (1999), Erdreich-Epstein A (1999), Chu J (1998), Shen M (2009)	4
ITK	7	GRB2	2	pull down, pull down	Bunnell SC (2000), Andreotti AH (1997)	2
CBL	7	CRKL	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Alsayed Y (2000), Alsayed Y (2000), Kyono WT (1998), Lin H (2001), Park RK (1998), Taher TE (2002), Sattler M (1997), Erdreich-Epstein A (1999), Erdreich-Epstein A (1999), Sattler M (1997), Sattler M (1997), Gesbert F (1998), Chin H (1997), Feshchenko EA (2004), Izadi KD (1998), de Jong R (1995), de Jong R (1995), Boussiotis VA (1997), Boussiotis VA (1997), Barber DL (1997), Uemura N (1999), Okabe S (2006), Alsayed Y (2000), Alsayed Y (2000), Brenner B (2001), van Leeuwen JE (1999), Ribon V (1996), Bhat A (1997), Bhat A (1997), Huang JY (2000), Chernock RD (2001), Chernock RD (2001), Grossmann AH (2004), Sakamoto H (2004), Nishihara T (2003), Peterson ME (2008), Fukazawa T (1996), Martelli MP (2001), Joshi S (2014), Grossmann A (2015)	40
FCHSD2	3	WAS	0	two hybrid	Wang J (2011)	1
GRB2	2	WIPF1	0	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Bisson N (2011), Wang J (2011), Huttlin EL (2017)	4
BTK	1	CBLB	3	affinity chromatography technology	Yasuda T (2002)	1
WAS	0	FYB1	0	affinity chromatography technology	Krause M (2000)	1
CSNK2A1	15	PRPF40A	5	enzymatic study, affinity chromatography technology, affinity chromatography technology	Zhang M (2011), Huttlin EL (2015), Huttlin EL (2017)	3
UBE2I	0	RANBP2	9	affinity chromatography technology, pull down, two hybrid, pull down, x-ray crystallography, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Zhang H (2002), Bandyopadhyay S (2010), Werner A (2012), Tatham MH (2005), Saitoh H (2002), Saitoh H (2002), Gareau JR (2012), Hein MY (2015), Sarkar K (2015), Huttlin EL (2017)	11
NCK2	2	ABI3	1	two hybrid	Rolland T (2014)	1
WAS	0	CBL	7	affinity chromatography technology	Watanabe Y (2013)	1
FYB1	0	UBE2I	0	affinity chromatography technology, affinity chromatography technology	Xiong Y (2017), Xiong Y (2017)	2
CBLB	3	CRKL	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Elly C (1999), Elly C (1999), Grossmann A (2015)	3
WIPF2	1	NCK2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Aspenstroem P (2002), Huttlin EL (2015), Huttlin EL (2017)	3
23380	0	WIPF1	0	affinity chromatography technology	Linkermann A (2009)	1
EGFR	5	CSNK2A1	15	affinity chromatography technology	Tong J (2014)	1
23380	0	ITSN2	7	affinity chromatography technology	Linkermann A (2009)	1
RAC1	7	GRB2	2	affinity chromatography technology	Huttlin EL (2017)	1
GRB2	2	CRKL	1	affinity chromatography technology	Park RK (1999)	1
UBE2I	0	RBBP5	3	enzymatic study	Nayak A (2014)	1
FYN	1	WAS	0	affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, enzymatic study	Banin S (1996), Banin S (1996), Banin S (1996), Banin S (1999), Rivero-Lezcano OM (1995), Suetsugu S (2002)	6
BTK	1	FYN	1	pull down	Cheng G (1994)	1
JMJD6	1	PRPF40A	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rahman S (2011), Huttlin EL (2015), Huttlin EL (2017)	3
CSNK2A1	15	RBBP5	3	affinity chromatography technology	Hauri S (2016)	1