PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
RIPK4	0	AURKB	2	affinity chromatography technology	Rodriguez J (2016)	1
TP53	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Wang C (2003), Akakura S (2001), Peng Y (2001), Nagata Y (1999), Wang J (2011), Burch L (2004), Taipale M (2012), Fogeron ML (2013), Walerych D (2004)	9
GLMP	0	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
NINL	1	CDC20	1	affinity chromatography technology, affinity chromatography technology	Wang Y (2007), Wang Y (2007)	2
MAPK6	1	TTK	4	two hybrid	Vinayagam A (2011)	1
CDC20	1	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
CEP135	2	KIAA0753	1	bioid, affinity chromatography technology	Gupta GD (2015), Hein MY (2015)	2
TTK	4	RPL7A	1	affinity chromatography technology	Hein MY (2015)	1
CNTRL	5	AURKB	2	bioid	Gupta GD (2015)	1
NTRK1	1	HERC5	2	affinity chromatography technology	Emdal KB (2015)	1
CDC20	1	KNL1	5	affinity chromatography technology	Craney A (2016)	1
AURKB	2	CEP170	4	affinity chromatography technology	Fogeron ML (2013)	1
HSP90AA1	7	VCP	6	affinity chromatography technology, affinity chromatography technology	Vij N (2006), Yu CC (2013)	2
ESR1	0	WDR5	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mo R (2006), Mo R (2006), Shi L (2011), Shi L (2011)	4
ODF2	1	TTK	4	bioid	Gupta GD (2015)	1
NTRK1	1	RPL7A	1	affinity chromatography technology	Emdal KB (2015)	1
ESR1	0	VCP	6	pull down	Nalvarte I (2010)	1
ODF2	1	KIAA0753	1	bioid	Gupta GD (2015)	1
CENPJ	6	TTK	4	bioid, bioid	Firat-Karalar EN (2014), Gupta GD (2015)	2
NTRK1	1	UBE4B	5	affinity chromatography technology	Emdal KB (2015)	1
VCP	6	TTK	4	affinity chromatography technology	Yu CC (2013)	1
TTK	4	NAA50	0	affinity chromatography technology	Hein MY (2015)	1
NIN	4	SSX2IP	0	bioid	Gupta GD (2015)	1
CDC20	1	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	DAngiolella V (2003), Kallio MJ (2002), Wassmann K (1998), Kramer ER (1998), Kallio M (1998), Kallio M (1998), Nilsson J (2008), Jeganathan KB (2006), Nath S (2011), Lee YJ (2008), Lara-Gonzalez P (2011), Mansfeld J (2011), Braunstein I (2007), Visconti R (2010), Ma HT (2011), Lee YJ (2008), DAngiolella V (2003), Lee SJ (2012), Fang G (1998), Fang G (1998), Wolthuis R (2008), Ban KH (2007), Ge S (2009), Tipton AR (2011), Westhorpe FG (2011), Uzunova K (2012), Kwan PS (2013), Sedgwick GG (2012), Eytan E (2013), Hyun SY (2013), Lim HJ (2013), Choi BH (2014), Fogeron ML (2013), Sackton KL (2014), Shoji S (2014), Han JS (2014), Lara-Gonzalez P (2011), Hein JB (2014), Vodermaier HC (2003), Yen AH (2010), Voets E (2015), Boekhout M (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Craney A (2016), Listovsky T (2013), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Hein JB (2016)	54
CEP135	2	CEP152	2	bioid	Gupta GD (2015)	1
NTRK1	1	SHMT2	3	affinity chromatography technology	Emdal KB (2015)	1
ODF2	1	APP	1	pull down	Olah J (2011)	1
CEP162	3	RPGRIP1L	2	bioid	Gupta GD (2015)	1
CNTROB	6	CDK2	0	affinity chromatography technology	Hein MY (2015)	1
RIPK4	0	HSP90AA1	7	affinity chromatography technology	Rodriguez J (2016)	1
CNTRL	5	CEP170	4	bioid	Gupta GD (2015)	1
C5AR2	1	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
NTRK1	1	RPS6KA1	3	affinity chromatography technology	Emdal KB (2015)	1
NINL	1	CDC27	2	affinity chromatography technology	Wang Y (2007)	1
NXF1	0	SLC39A9	1	affinity chromatography technology	Castello A (2012)	1
CEP162	3	CEP170	4	affinity chromatography technology, affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
NTRK1	1	TTK	4	affinity chromatography technology	Emdal KB (2015)	1
CENPJ	6	SSX2IP	0	bioid	Gupta GD (2015)	1
KIAA0753	1	TTK	4	bioid	Gupta GD (2015)	1
HSP90AA1	7	APP	1	affinity chromatography technology	Kumar P (2007)	1
PLK4	1	CEP128	1	bioid	Firat-Karalar EN (2014)	1
RAD52	5	HSP90AA1	7	affinity chromatography technology	Du Y (2009)	1
CEP128	1	CEP170	4	bioid	Gupta GD (2015)	1
AURKB	2	TTK	4	affinity chromatography technology	Huttlin EL (2015)	1
SLC2A12	2	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
CDC27	2	CDH1	4	affinity chromatography technology, affinity chromatography technology	Chen M (2012), Tran K (2010)	2
HSP90AA1	7	FZR1	1	genetic interference	Srivas R (2016)	1
CDK2	0	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Craney A (2016), Huttlin EL (2017)	4
EGLN3	0	IBTK	3	affinity chromatography technology	Rodriguez J (2016)	1
TTK	4	5430	0	enzymatic study	Nekhai S (1997)	1
KIAA0753	1	CEP44	2	bioid	Gupta GD (2015)	1
MAPK6	1	5430	0	affinity chromatography technology	Rodriguez J (2016)	1
DCTN1	6	TTK	4	bioid	Gupta GD (2015)	1
CDH1	4	RPL7A	1	bioid	Guo Z (2014)	1
RPGRIP1L	2	KIAA0753	1	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
CEP120	5	TTK	4	bioid	Gupta GD (2015)	1
CDH1	4	HDLBP	9	bioid	Guo Z (2014)	1
CEP63	2	NAA50	0	genetic interference	Horlbeck MA (2018)	1
ODF2	1	CEP135	2	bioid	Gupta GD (2015)	1
PLK4	1	TTK	4	bioid	Firat-Karalar EN (2014)	1
CEP120	5	CEP170	4	bioid	Gupta GD (2015)	1
CDC20	1	CDC16	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kallio MJ (2002), Kallio M (1998), Nilsson J (2008), Hutchins JR (2010), Fogeron ML (2013), Hein JB (2014), Hein MY (2015), Kelly A (2014), Craney A (2016), Listovsky T (2013), Qiao R (2016), Izawa D (2012)	12
CEP120	5	CNTROB	6	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
AURKB	2	SNW1	0	affinity chromatography technology	Fogeron ML (2013)	1
SSX2IP	0	TP53	0	bioid	Gupta GD (2015)	1
CEP128	1	NINL	1	bioid	Gupta GD (2015)	1
ESR1	0	HSP90AA1	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nair SC (1996), Lee MO (2002), Fan M (2005), Tateishi Y (2004), Fiskus W (2007), Powell E (2010), Suzuki T (2011), Berry NB (2008), Sumanasekera WK (2003), Taipale M (2012), Donley C (2013), Donley C (2013), Dhamad AE (2016)	13
NXF1	0	DCTN1	6	affinity chromatography technology	Castello A (2012)	1
CDH1	4	TTK	4	bioid	Guo Z (2014)	1
NIN	4	TP53	0	bioid	Gupta GD (2015)	1
SSX2IP	0	TTK	4	bioid	Gupta GD (2015)	1
CEP63	2	SSX2IP	0	bioid	Gupta GD (2015)	1
PCM1	5	CEP120	5	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
TTK	4	APP	1	pull down	Olah J (2011)	1
RPS6KA1	3	TTK	4	two hybrid	Vinayagam A (2011)	1
RPGRIP1L	2	IBTK	3	bioid	Gupta GD (2015)	1
CEP128	1	CEP120	5	bioid	Gupta GD (2015)	1
CEP170	4	NIN	4	affinity chromatography technology, bioid, affinity chromatography technology	Huttlin EL (2015), Gupta GD (2015), Huttlin EL (2017)	3
CEP120	5	CEP152	2	bioid	Gupta GD (2015)	1
EGLN3	0	MAPK6	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang J (2011), Rodriguez J (2016), Rodriguez J (2016), Rodriguez J (2016), Rodriguez J (2016)	5
SLC18A1	2	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
PCM1	5	CEP170	4	affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
CEP128	1	TP53	0	bioid	Gupta GD (2015)	1
ESR1	0	UBE4B	5	two hybrid	Arroyo R (2015)	1
EGLN3	0	TTK	4	affinity chromatography technology	Rodriguez J (2016)	1
VCP	6	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Yu CC (2013), Fogeron ML (2013)	3
CNTRL	5	KIAA0753	1	bioid	Gupta GD (2015)	1
LPAR4	2	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
TTK	4	UBE4B	5	affinity chromatography technology	Liu C (2011)	1
CDK2	0	HDLBP	9	affinity chromatography technology	Neganova I (2011)	1
NPY2R	0	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
CEP128	1	PCM1	5	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
NINL	1	TP53	0	bioid	Gupta GD (2015)	1
ESR1	0	USP16	0	affinity chromatography technology	Okada M (2015)	1
AURKB	2	CDC27	2	affinity chromatography technology	Nguyen HG (2005)	1
PCM1	5	RPGRIP1L	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	5
ESR1	0	RPL7A	1	affinity chromatography technology, affinity chromatography technology	Ambrosino C (2010), Tarallo R (2011)	2
CEP128	1	RPGRIP1L	2	bioid	Gupta GD (2015)	1
CEP152	2	RPGRIP1L	2	bioid	Gupta GD (2015)	1
CEP120	5	TP53	0	bioid	Gupta GD (2015)	1
TTK	4	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu ST (2003), Cui Y (2010), Cui Y (2010), Liu C (2011)	4
CEP44	2	IBTK	3	bioid	Gupta GD (2015)	1
EGLN3	0	AURKB	2	affinity chromatography technology	Rodriguez J (2016)	1
CDK2	0	TP53	0	enzymatic study, enzymatic study, imaging technique	Luciani MG (2000), Tsai CH (2009), Chen TC (2014)	3
PCM1	5	KIAA0753	1	affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
EGLN3	0	5430	0	affinity chromatography technology	Rodriguez J (2016)	1
NIN	4	PCM1	5	bioid	Gupta GD (2015)	1
FAM174A	2	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
CEP89	2	CEP170	4	bioid	Gupta GD (2015)	1
TTK	4	ESPL1	2	affinity chromatography technology	Hein MY (2015)	1
TTK	4	HSP90AA1	7	enzymatic study, affinity chromatography technology	Woodford MR (2016), Woodford MR (2016)	2
NXF1	0	GEMIN5	1	affinity chromatography technology	Castello A (2012)	1
CEP63	2	CEP44	2	bioid	Gupta GD (2015)	1
VCP	6	APP	1	affinity chromatography technology	Jang JK (2017)	1
AURKB	2	FZR1	1	affinity chromatography technology, affinity chromatography technology	Nguyen HG (2005), Nguyen HG (2005)	2
CDK2	0	VCP	6	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Fogeron ML (2013)	2
TTK	4	USP16	0	enzymatic study	Stratford JK (2017)	1
SHMT2	3	APP	1	pull down	Olah J (2011)	1
MAPK6	1	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
CENPJ	6	CEP170	4	bioid	Gupta GD (2015)	1
RPS6KA1	3	VCP	6	two hybrid	Vinayagam A (2011)	1
NTRK1	1	SNW1	0	affinity chromatography technology	Emdal KB (2015)	1
POC1A	3	TTK	4	bioid	Gupta GD (2015)	1
CEP128	1	CEP162	3	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
EGLN3	0	CDC20	1	affinity chromatography technology	Rodriguez J (2016)	1
RPGRIP1L	2	TTK	4	bioid	Gupta GD (2015)	1
UBE4B	5	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Wu H (2011), Wu H (2011), Wu H (2011), Wu H (2011), Wu H (2011), Zhang Y (2014), Du C (2016), Du C (2016), Du C (2016)	9
SNW1	0	CDC27	2	affinity chromatography technology	Lleres D (2010)	1
NINL	1	CEP170	4	bioid	Gupta GD (2015)	1
CEP128	1	CNTROB	6	bioid	Gupta GD (2015)	1
CEP135	2	PCM1	5	bioid, affinity chromatography technology	Gupta GD (2015), Hein MY (2015)	2
NIN	4	DCTN1	6	bioid	Gupta GD (2015)	1
PCM1	5	TTK	4	bioid	Gupta GD (2015)	1
UBE4B	5	CDC27	2	affinity chromatography technology	Liu C (2011)	1
SHMT2	3	RPGRIP1L	2	affinity chromatography technology	Castello A (2012)	1
C5AR2	1	GLMP	0	affinity chromatography technology	Huttlin EL (2017)	1
NINL	1	CEP162	3	bioid	Gupta GD (2015)	1
IL13RA2	0	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
CEP162	3	CEP120	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	5
CDC16	2	ESPL1	2	affinity chromatography technology	Huttlin EL (2017)	1
CEP63	2	CEP128	1	bioid, bioid, bioid	Firat-Karalar EN (2014), Gupta GD (2015), Gupta GD (2015)	3
PCM1	5	CEP89	2	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
NINL	1	FZR1	1	affinity chromatography technology, affinity chromatography technology	Wang Y (2007), Wang Y (2007)	2
FZR1	1	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhou Y (2003), Kramer ER (1998), Farhana L (2002), Cen B (2010), Sorensen CS (2001), Binne UK (2007), Wang X (2008), Tran K (2008), Wang LY (2012), Wang LY (2012), Ban KH (2007), Lv XB (2010), Huang KT (2012), Song MS (2011), Fukushima H (2013), Lau AW (2013), Cotto-Rios XM (2011), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Choi BH (2014), Jeganathan KB (2006), Fang G (1998), Sedgwick GG (2012), Kelly A (2014), Listovsky T (2013), Pavlides SC (2016), Huttlin EL (2017)	28
SSX2IP	0	KIAA0753	1	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
RIPK4	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
TTK	4	CDC16	2	affinity chromatography technology	Liu ST (2003)	1
TTK	4	TP53	0	affinity chromatography technology, pull down, enzymatic study	Huang YF (2009), Huang YF (2009), Huang YF (2009)	3
CEP170	4	KIF2A	3	bioid, affinity chromatography technology	Gupta GD (2015), Hein MY (2015)	2
NINL	1	TTK	4	bioid	Gupta GD (2015)	1
NXF1	0	CEP128	1	affinity chromatography technology	Castello A (2012)	1
NXF1	0	CENPJ	6	affinity chromatography technology	Castello A (2012)	1
CNTRL	5	RPGRIP1L	2	bioid	Gupta GD (2015)	1
EGLN3	0	KIF2A	3	affinity chromatography technology	Rodriguez J (2016)	1
CEP152	2	CEP128	1	bioid, bioid	Firat-Karalar EN (2014), Gupta GD (2015)	2
NTRK1	1	GEMIN5	1	affinity chromatography technology	Emdal KB (2015)	1
EGLN3	0	CENPJ	6	affinity chromatography technology	Rodriguez J (2016)	1
TP53	0	KIF2A	3	genetic interference	Sun CN (2010)	1
RAD52	5	5430	0	affinity chromatography technology	Liu J (2002)	1
TTK	4	CDCA8	0	enzymatic study	Jelluma N (2008)	1
ODF2	1	CEP170	4	bioid	Gupta GD (2015)	1
NTRK1	1	5430	0	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	CDC27	2	affinity chromatography technology	Emdal KB (2015)	1
CDK2	0	ESR1	0	enzymatic study, affinity chromatography technology	Zhou W (2014), Zhou W (2014)	2
TTK	4	RAD52	5	enzymatic study	Lim G (2017)	1
SNW1	0	DCTN1	6	affinity chromatography technology	Lleres D (2010)	1
ODF2	1	SSX2IP	0	bioid	Gupta GD (2015)	1
RPGRIP1L	2	CEP170	4	affinity chromatography technology, affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
SNW1	0	HSP90AA1	7	affinity chromatography technology	Lleres D (2010)	1
CEP128	1	CEP89	2	bioid	Gupta GD (2015)	1
POC1A	3	IBTK	3	bioid	Gupta GD (2015)	1
EGLN3	0	NIN	4	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	CDK2	0	affinity chromatography technology	Rodriguez J (2016)	1
HSP90AA1	7	RPS6KA1	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Varjosalo M (2013)	2
CEP44	2	TTK	4	bioid	Gupta GD (2015)	1
FZR1	1	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Stewart S (2005), Stewart S (2005), Wang Y (2007), Wang Y (2007), Tian W (2012), Hyun SY (2013), Hyun SY (2013)	7
CEP135	2	CEP44	2	bioid	Gupta GD (2015)	1
APLNR	1	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
CNTRL	5	NIN	4	bioid	Gupta GD (2015)	1
WDR5	2	SSX2IP	0	two hybrid	Rolland T (2014)	1
CEP162	3	KIAA0753	1	affinity chromatography technology, affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
KIAA0753	1	CEP170	4	bioid	Gupta GD (2015)	1
NTRK1	1	PCM1	5	affinity chromatography technology	Emdal KB (2015)	1
CDC27	2	CDC16	2	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Ollendorff V (1997), Kallio M (1998), Gmachl M (2000), Kraft C (2003), Li Y (1997), Lara-Gonzalez P (2011), Binne UK (2007), van Zon W (2010), Dube P (2005), Holzmann J (2011), Hayes MJ (2006), Tugendreich S (1995), Havugimana PC (2012), Vodermaier HC (2003), Wan C (2015), Hein MY (2015), Kelly A (2014), Listovsky T (2013), Qiao R (2016), Huttlin EL (2017), Boldt K (2016)	22
RIPK4	0	TTK	4	affinity chromatography technology	Rodriguez J (2016)	1
NINL	1	PCM1	5	bioid	Gupta GD (2015)	1
CNTRL	5	PCM1	5	bioid	Gupta GD (2015)	1
NINL	1	DCTN1	6	affinity chromatography technology	Boldt K (2016)	1
CEP128	1	KIAA0753	1	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
ESR1	0	SHMT2	3	pull down	Nalvarte I (2010)	1
NXF1	0	SNW1	0	affinity chromatography technology	Castello A (2012)	1
CNTRL	5	CEP152	2	bioid	Gupta GD (2015)	1
NXF1	0	CDC16	2	affinity chromatography technology	Castello A (2012)	1
EGLN3	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
CEP170	4	DCTN1	6	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
TTK	4	WDR5	2	biochemical	Havugimana PC (2012)	1
CHRM4	5	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
TTK	4	CDK2	0	enzymatic study	Nekhai S (1997)	1
CEP120	5	KNL1	5	bioid	Gupta GD (2015)	1
VCP	6	HDLBP	9	affinity chromatography technology	Yu CC (2013)	1
PCM1	5	ODF2	1	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
DCTN1	6	AURKB	2	bioid	Gupta GD (2015)	1
CEP128	1	TTK	4	bioid	Gupta GD (2015)	1
CENPJ	6	KIAA0753	1	bioid	Gupta GD (2015)	1
EGLN3	0	CDC27	2	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	DCTN1	6	affinity chromatography technology	Rodriguez J (2016)	1
CEP120	5	SSX2IP	0	bioid	Gupta GD (2015)	1
AURKB	2	RAD52	5	enzymatic study	Lim G (2017)	1
NXF1	0	RPGRIP1L	2	affinity chromatography technology, bioid	Castello A (2012), Gupta GD (2015)	2
TP53	0	ESR1	0	pull down, affinity chromatography technology, affinity chromatography technology	Liu G (2000), Duong V (2007), Saxena R (2016)	3
NTRK1	1	CDK2	0	affinity chromatography technology	Emdal KB (2015)	1
CEP128	1	CEP135	2	affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
NINL	1	CENPJ	6	bioid	Gupta GD (2015)	1
ODF2	1	CEP120	5	bioid	Gupta GD (2015)	1
CENPJ	6	IBTK	3	bioid	Gupta GD (2015)	1
CEP120	5	IBTK	3	bioid	Gupta GD (2015)	1
CEP63	2	NIN	4	bioid	Firat-Karalar EN (2014)	1
SNW1	0	HDLBP	9	affinity chromatography technology	Lleres D (2010)	1
CEP63	2	KIAA0753	1	bioid, bioid, affinity chromatography technology, bioid	Firat-Karalar EN (2014), Firat-Karalar EN (2014), Firat-Karalar EN (2014), Gupta GD (2015)	4
TTK	4	HDLBP	9	biochemical	Havugimana PC (2012)	1
CEP128	1	CEP44	2	bioid	Gupta GD (2015)	1
CEP63	2	TTK	4	bioid	Gupta GD (2015)	1
NTRK1	1	WDR5	2	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rao R (2010), Taipale M (2012), Emdal KB (2015)	3
CEP152	2	TP53	0	bioid	Gupta GD (2015)	1
ERI3	0	TTK	4	biochemical	Havugimana PC (2012)	1
RPGRIP1L	2	SSX2IP	0	bioid	Gupta GD (2015)	1
RPGRIP1L	2	TP53	0	bioid	Gupta GD (2015)	1
EGLN3	0	KNL1	5	affinity chromatography technology	Rodriguez J (2016)	1
NINL	1	RPGRIP1L	2	bioid	Gupta GD (2015)	1
NXF1	0	ESPL1	2	affinity chromatography technology	Castello A (2012)	1
CENPJ	6	CEP120	5	bioid, bioid	Firat-Karalar EN (2014), Gupta GD (2015)	2
PCM1	5	CENPJ	6	bioid, bioid, affinity chromatography technology	Gupta GD (2015), Gupta GD (2015), Hein MY (2015)	3
NINL	1	CEP89	2	bioid	Gupta GD (2015)	1
NTRK1	1	CEP170	4	affinity chromatography technology	Emdal KB (2015)	1
TTK	4	UTRN	6	affinity chromatography technology	Hein MY (2015)	1
CNTRL	5	ODF2	1	bioid	Gupta GD (2015)	1
VCP	6	CDC27	2	affinity chromatography technology	Yu CC (2013)	1
CEP162	3	CEP89	2	bioid	Gupta GD (2015)	1
WDR5	2	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
MAPK6	1	CEP170	4	affinity chromatography technology	Rodriguez J (2016)	1
TTK	4	TACC2	4	affinity chromatography technology	Dou Z (2004)	1
GRPR	0	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
CDCA8	0	AURKB	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Sampath SC (2004), Gassmann R (2004), Gassmann R (2004), Xu Z (2009), Knauer SK (2006), Ban R (2011), Jeyaprakash AA (2007), Jelluma N (2008), Gomez V (2010), Gomez V (2010), Klein UR (2009)	11
KIAA0753	1	CEP120	5	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
CEP152	2	PCM1	5	bioid	Gupta GD (2015)	1
FZR1	1	TP53	0	enzymatic study	Gmachl M (2000)	1
UBE4B	5	VCP	6	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Matsumoto M (2004), Matsumoto M (2004), Boehm S (2011), Takahata M (2008), Morreale G (2009), Fernandez-Saiz V (2010), Fernandez-Saiz V (2010), Raman M (2015), Wang T (2016), Huttlin EL (2017)	10
NTRK1	1	DCTN1	6	affinity chromatography technology	Emdal KB (2015)	1
TP53	0	SLC2A12	2	affinity chromatography technology	Fogeron ML (2013)	1
CEP89	2	SSX2IP	0	bioid	Gupta GD (2015)	1
MAS1	2	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
CEP135	2	SSX2IP	0	bioid, affinity chromatography technology	Gupta GD (2015), Hein MY (2015)	2
EGLN3	0	PCM1	5	affinity chromatography technology	Rodriguez J (2016)	1
CEP128	1	CDC20	1	bioid	Gupta GD (2015)	1
CDH1	4	UTRN	6	bioid	Guo Z (2014)	1
NTRK1	1	VCP	6	affinity chromatography technology	Emdal KB (2015)	1
VCP	6	ESPL1	2	affinity chromatography technology	Yu CC (2013)	1
CEP128	1	CNTRL	5	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
EGLN3	0	UTRN	6	affinity chromatography technology	Rodriguez J (2016)	1
SNW1	0	TTK	4	affinity chromatography technology	Lleres D (2010)	1
TP53	0	WDR5	2	pull down, pull down	Dou Y (2005), Tang Z (2013)	2
ODF2	1	IBTK	3	bioid	Gupta GD (2015)	1
CEP44	2	CEP170	4	bioid	Gupta GD (2015)	1
RPGRIP1L	2	KIF2A	3	affinity chromatography technology	Gupta GD (2015)	1
NTRK1	1	HDLBP	9	affinity chromatography technology	Emdal KB (2015)	1
TTK	4	KIF2A	3	affinity chromatography technology	Hein MY (2015)	1
POC1A	3	CEP44	2	bioid	Gupta GD (2015)	1
CEP152	2	KIAA0753	1	bioid, bioid	Firat-Karalar EN (2014), Firat-Karalar EN (2014)	2
CNTRL	5	TTK	4	bioid	Gupta GD (2015)	1
EGLN3	0	VCP	6	affinity chromatography technology	Rodriguez J (2016)	1
CDH1	4	HSP90AA1	7	affinity chromatography technology	Catimel B (2005)	1
ESR1	0	TTK	4	affinity chromatography technology	Han SJ (2016)	1
CEP128	1	IBTK	3	bioid	Gupta GD (2015)	1
ESR1	0	5430	0	affinity chromatography technology, imaging technique, imaging technique, pull down	Ambrosino C (2010), Zhang H (2006), Zhang H (2006), Nalvarte I (2010)	4
TTK	4	KNL1	5	enzymatic study	Yamagishi Y (2012)	1
DCTN1	6	KIF2A	3	bioid	Gupta GD (2015)	1
SNW1	0	WDR5	2	affinity chromatography technology	Lleres D (2010)	1
FZR1	1	CDC16	2	unspecified method, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Hein MY (2015), Huttlin EL (2017)	3
CEP152	2	TTK	4	bioid	Gupta GD (2015)	1
PCM1	5	CEP63	2	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
DCTN1	6	CEP44	2	bioid	Gupta GD (2015)	1
CEP89	2	TTK	4	bioid	Gupta GD (2015)	1
CENPJ	6	GEMIN5	1	affinity chromatography technology	Hein MY (2015)	1
PLK4	1	CEP152	2	bioid, bioid, affinity chromatography technology	Firat-Karalar EN (2014), Gupta GD (2015), Hein MY (2015)	3
CEP135	2	CEP170	4	bioid	Gupta GD (2015)	1
HSP90AA1	7	AURKB	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Taipale M (2012), Fogeron ML (2013), Huttlin EL (2015), Huttlin EL (2017)	5
NXF1	0	TTK	4	affinity chromatography technology	Castello A (2012)	1
CNTRL	5	SSX2IP	0	bioid	Gupta GD (2015)	1
NIN	4	TTK	4	bioid	Gupta GD (2015)	1
CEP135	2	TTK	4	bioid	Gupta GD (2015)	1
TTK	4	TTK	4	affinity chromatography technology, enzymatic study	Hutchins JR (2010), Sawasaki T (2008)	2
CEP128	1	5430	0	bioid	Gupta GD (2015)	1
CDC20	1	TTK	4	affinity chromatography technology	Cui Y (2010)	1
SHMT2	3	TTK	4	affinity chromatography technology	Castello A (2012)	1
CNTROB	6	TTK	4	bioid	Gupta GD (2015)	1
ODF2	1	CEP44	2	bioid	Gupta GD (2015)	1
EGLN3	0	SSX2IP	0	affinity chromatography technology	Rodriguez J (2016)	1
VCP	6	5430	0	affinity chromatography technology, affinity chromatography technology	He J (2017), He J (2017)	2
PLPPR1	3	TTK	4	affinity chromatography technology	Huttlin EL (2015)	1
TTK	4	GEMIN5	1	affinity chromatography technology	Hein MY (2015)	1
MAPK6	1	SNW1	0	two hybrid	Vinayagam A (2011)	1
CEP135	2	IBTK	3	bioid	Gupta GD (2015)	1
RPS6KA1	3	ESR1	0	enzymatic study	Joel PB (1998)	1
TP53	0	SNW1	0	affinity chromatography technology	Fogeron ML (2013)	1
MAPK6	1	AURKB	2	affinity chromatography technology	Rodriguez J (2016)	1
CEP128	1	SSX2IP	0	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
PLK4	1	KIF2A	3	bioid	Firat-Karalar EN (2014)	1
CEP135	2	CEP162	3	affinity chromatography technology, affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
AURKB	2	APP	1	pull down	Olah J (2011)	1
AURKB	2	CDC20	1	affinity chromatography technology, affinity chromatography technology	Nguyen HG (2005), Nguyen HG (2005)	2
CNTRL	5	CEP89	2	bioid	Gupta GD (2015)	1
HERC5	2	TP53	0	affinity chromatography technology	Huang YF (2014)	1
5430	0	CDK2	0	biochemical	Nekhai S (1997)	1
IBTK	3	ESPL1	2	affinity chromatography technology	Hein MY (2015)	1
ESR1	0	HDLBP	9	pull down	Nalvarte I (2010)	1
CEP89	2	KIAA0753	1	bioid	Gupta GD (2015)	1
CEP162	3	TTK	4	bioid	Gupta GD (2015)	1
LAMP2	0	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
CDK2	0	FZR1	1	enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Sorensen CS (2001), Fukushima H (2013), Lau AW (2013), Chang L (2015), Huttlin EL (2017)	5
CEP128	1	NIN	4	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
CEP63	2	CEP152	2	bioid, bioid, bioid, bioid	Firat-Karalar EN (2014), Firat-Karalar EN (2014), Gupta GD (2015), Gupta GD (2015)	4
CEP152	2	CENPJ	6	bioid	Firat-Karalar EN (2014)	1
MAPK6	1	CNTRL	5	two hybrid	Bandyopadhyay S (2010)	1
PCM1	5	IBTK	3	bioid	Gupta GD (2015)	1
TTK	4	HERC5	2	affinity chromatography technology	Hein MY (2015)	1
EGLN3	0	CEP170	4	affinity chromatography technology	Rodriguez J (2016)	1
CDK2	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Varjosalo M (2013)	2
TTK	4	IBTK	3	affinity chromatography technology	Hein MY (2015)	1
CEP128	1	ODF2	1	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
PCM1	5	CEP162	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	5
PLK4	1	CEP63	2	bioid	Firat-Karalar EN (2014)	1
UBE4B	5	HDLBP	9	biochemical	Havugimana PC (2012)	1
NTRK1	1	KIF2A	3	affinity chromatography technology	Emdal KB (2015)	1
CEP162	3	SSX2IP	0	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
NXF1	0	5430	0	affinity chromatography technology	Castello A (2012)	1
CEP135	2	CEP120	5	bioid	Gupta GD (2015)	1
TP53	0	AURKB	2	affinity chromatography technology	Wu L (2011)	1
NXF1	0	HSP90AA1	7	affinity chromatography technology	Castello A (2012)	1
NINL	1	KIAA0753	1	bioid	Gupta GD (2015)	1
TP53	0	RPL7A	1	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
CEP170	4	TTK	4	bioid	Gupta GD (2015)	1
EGLN3	0	SNW1	0	affinity chromatography technology	Rodriguez J (2016)	1
FZR1	1	TTK	4	affinity chromatography technology	Cui Y (2010)	1
CNTRL	5	CEP162	3	bioid	Gupta GD (2015)	1
CEP135	2	TP53	0	bioid	Gupta GD (2015)	1
SLC39A9	1	TTK	4	affinity chromatography technology	Huttlin EL (2017)	1
PCM1	5	SSX2IP	0	affinity chromatography technology, affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	4