Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
SLC4A1 rs45545233 CC + CT atenolol efficacy yes The grouped CC and CT genotypes were associated with a smaller decrease in diastolic blood pressure in a meta-analysis of patients receiving metoprolol or atenolol monotherapy (discovery cohort) and in patients receiving atenolol addon therapy (replication cohort). Genotypes CC + CT are associated with decreased response to atenolol or metoprolol in people with Hypertension as compared to genotype TT. 31033190 1451106148