Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
FBXL17	rs4431329	T	hydrochlorothiazide	efficacy	no	The SNP was discovered in two independent cohorts, although no SNPs reached genome wide significance. The authors then considered P<1 x10^-5 as a threshold for significance (based on the results from a Q-Q plot distribution reference line). Using this revised threshold the authors reported that this SNP was associated with a lower decrease in diastolic blood pressure after hydrochlorothiazide treatment.	Allele T is associated with decreased response to hydrochlorothiazide in people with Essential hypertension as compared to allele A.	25695618	1444703675
FBXL17	rs7706429	G	hydrochlorothiazide	efficacy	no	The SNP was discovered in two independent cohorts, although no SNPs reached genome wide significance. The authors then considered P<1 x10^-5 as a threshold for significance (based on the results from a Q-Q plot distribution reference line). Using this revised threshold the authors reported that this SNP was associated with a lower decrease in diastolic blood pressure after hydrochlorothiazide treatment.	Allele G is associated with decreased response to hydrochlorothiazide in people with Essential hypertension as compared to allele A.	25695618	1444703691