PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
SIAH1	2	GAPDH	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee SY (2012), Lee SB (2012), Tristan CA (2015), Suarez S (2015)	4
PHC2	3	KIFC3	3	two hybrid	Rolland T (2014)	1
STAT3	0	PIAS3	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Wang LH (2001), Okumura F (2010), Yamamoto T (2003), Yamamoto T (2003), Tsuruma R (2008), Liu B (1998), Wang J (2011)	7
UBE2V2	0	SIAH1	2	two hybrid	Markson G (2009)	1
SIAH1	2	TFDP1	3	two hybrid	Wang J (2011)	1
SIAH2	0	SNCA	0	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Liani E (2004), Rott R (2008), Rott R (2008), Szargel R (2009), Rott R (2011)	5
TBL1X	1	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Matsuzawa SI (2001), Li J (2008), Li J (2008), Chen TC (2014)	4
RNF2	1	UBE2D2	0	enzymatic study, two hybrid, pull down	Lee SJ (2001), Markson G (2009), Dou H (2012)	3
SDCBP	0	MAPRE3	0	two hybrid	Rolland T (2014)	1
PKD1	18	SIAH1	2	two hybrid, affinity chromatography technology	Kim H (2004), Kim H (2004)	2
MX1	0	UBE2I	0	two hybrid, affinity chromatography technology	Brantis-de-Carvalho CE (2015), Brantis-de-Carvalho CE (2015)	2
TRIM7	2	UBE2D2	0	two hybrid	Napolitano LM (2011)	1
SIAH2	0	PIAS3	2	pull down	Depaux A (2007)	1
COPS5	0	NPM1	0	affinity chromatography technology	Bennett EJ (2010)	1
NECTIN2	0	SIAH1	2	two hybrid	Rolland T (2014)	1
LATS2	1	CDC23	3	affinity chromatography technology, affinity chromatography technology	Zhu C (2018), Zhu C (2018)	2
SIAH1	2	116349	0	two hybrid	Rolland T (2014)	1
LATS2	1	TRIM27	2	bioid	Couzens AL (2013)	1
SIAH1	2	UPP2	1	two hybrid	Rolland T (2014)	1
PRR20E	0	SIAH2	0	affinity chromatography technology	Huttlin EL (2017)	1
EEF1D	3	SIAH2	0	two hybrid	Wang J (2011)	1
UBE2K	0	RNF2	1	two hybrid, pull down, affinity chromatography technology, two hybrid	Lee SJ (2001), Lee SJ (2001), Lee SJ (2001), Markson G (2009)	4
PSMC6	0	SDCBP	0	two hybrid	Rolland T (2014)	1
SEPT4	2	SIAH1	2	affinity chromatography technology	Garrison JB (2011)	1
SIAH1	2	CDK5R1	0	two hybrid	Rolland T (2014)	1
UBE2N	1	TRIM27	2	two hybrid, affinity chromatography technology	Napolitano LM (2011), Napolitano LM (2011)	2
RNF2	1	RPS19BP1	0	affinity chromatography technology	Cao Q (2014)	1
UBE2N	1	SIAH1	2	two hybrid	Markson G (2009)	1
FLI1	2	SIAH1	2	two hybrid	Rolland T (2014)	1
UBE2L6	0	FLT3	5	affinity chromatography technology, pull down	Buchwald M (2010), Buchwald M (2010)	2
TRIM23	3	UBE2D1	0	pull down, pull down	Vichi A (2005), Vichi A (2006)	2
MYD88	1	SIAH2	0	two hybrid	Wang J (2011)	1
SIAH1	2	AFF4	2	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
GAPDH	0	MAP3K5	1	affinity chromatography technology	Tristan CA (2015)	1
KHDRBS3	0	PRPF31	0	two hybrid	Rolland T (2014)	1
CDC34	3	SIAH1	2	two hybrid	Rolland T (2014)	1
OTUB2	0	TRIM27	2	two hybrid	Hayes SD (2012)	1
BAG1	1	TRIM23	3	two hybrid, two hybrid	Venkatesan K (2009), Rolland T (2014)	2
BCL6	6	PML	7	two hybrid	Dhordain P (2000)	1
GAPDH	0	NPM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee SB (2012), Lee SB (2012), Chen R (2013)	3
UBE2D3	1	TRIM27	2	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Markson G (2009), Napolitano LM (2011), Napolitano LM (2011), Napolitano LM (2011)	4
APC	5	CTNNB1	30	affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Su LK (1993), Su LK (1993), Kucerova D (2001), Tickenbrock L (2003), Davies G (2001), Ryo A (2001), Homma MK (2002), Tickenbrock L (2003), Davies G (2001), Satoh K (1997), Eklof Spink K (2001), Eklof Spink K (2001), Sierra J (2006), Choi J (2004), Huang X (2009), Brocardo MG (2011), Xing Y (2004), Xing Y (2004), Xing Y (2004), Hamada F (2004), Hamada F (2004), Schneikert J (2013), Hsi LC (1999), Hein MY (2015), Hein MY (2015), Chen TC (2014), Kuslansky Y (2016), Novellasdemunt L (2017), Novellasdemunt L (2017)	29
RARA	5	PSMC5	4	pull down, pull down, affinity chromatography technology, two hybrid	Zechel C (2002), vom Baur E (1996), Ferry C (2009), Choi HS (1996)	4
PEG10	2	SIAH1	2	two hybrid, pull down, two hybrid	Okabe H (2003), Okabe H (2003), Rolland T (2014)	3
BAG1	1	PEG10	2	biochemical	Kristensen AR (2012)	1
TRIM27	2	CDC23	3	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
SIAH2	0	TNK2	7	affinity chromatography technology	Buchwald M (2012)	1
UBE2V2	0	XIAP	0	two hybrid	Markson G (2009)	1
DLD	1	EEF1D	3	affinity chromatography technology	Malty RH (2017)	1
LMNA	2	SIAH1	2	two hybrid	Dittmer TA (2014)	1
SIAH2	0	UBE2L6	0	affinity chromatography technology	Wheeler TC (2002)	1
SIAH2	0	PIAS1	4	two hybrid, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Depaux A (2007), Depaux A (2007), Depaux A (2007), Depaux A (2007), Lee JH (2016)	5
SIAH1	2	SPATC1L	0	two hybrid	Rolland T (2014)	1
MAP3K5	1	PSMC5	4	affinity chromatography technology	Um JW (2010)	1
SIAH1	2	UBE2D1	0	two hybrid, two hybrid, pull down, pull down, pull down	Matsuzawa SI (2001), Markson G (2009), Dimitrova YN (2010), Rott R (2008), Liu QY (2008)	5
SIAH1	2	MOB3C	2	two hybrid	Rolland T (2014)	1
PIAS1	4	ATXN7	0	affinity chromatography technology	Janer A (2010)	1
SIAH1	2	KHDRBS3	0	two hybrid, two hybrid, pull down, two hybrid	Rual JF (2005), Venables JP (2004), Venables JP (2004), Buchwald M (2012)	4
UBE2I	0	NOL6	2	enzymatic study	Matafora V (2009)	1
SIAH1	2	PSMC5	4	affinity chromatography technology	Kulikov R (2010)	1
UBE2D1	0	RLIM	1	two hybrid, pull down, pull down, pull down	Markson G (2009), Gontan C (2012), Her YR (2009), Gao K (2016)	4
DLD	1	UBE2K	0	affinity chromatography technology	Malty RH (2017)	1
HTT	14	GAPDH	0	affinity chromatography technology	Bae BI (2006)	1
BCL6	6	SIAH1	2	two hybrid	Rolland T (2014)	1
CTNNB1	30	CDK5R1	0	pull down, affinity chromatography technology	Kesavapany S (2001), Kesavapany S (2001)	2
WDYHV1	0	QRICH1	8	affinity chromatography technology	Huttlin EL (2017)	1
PHC2	3	MCM2	3	two hybrid	Stelzl U (2005)	1
AFF1	1	SIAH2	0	two hybrid, far western blotting, pull down	Bursen A (2004), Bursen A (2004), Bursen A (2004)	3
TP53BP2	5	TBC1D22B	2	two hybrid	Rolland T (2014)	1
MCM2	3	NPM1	0	affinity chromatography technology	Drissi R (2015)	1
UBE2D3	1	SIAH1	2	two hybrid, two hybrid, pull down, pull down, pull down	van Wijk SJ (2009), Markson G (2009), Liu M (2012), Mei Y (2007), Kim SY (2009)	5
PEG3	2	SIAH2	0	affinity chromatography technology, two hybrid	Relaix F (2000), Relaix F (2000)	2
PIAS1	4	FLI1	2	enzymatic study	van den Akker E (2005)	1
SIAH1	2	FZD9	10	two hybrid	Rolland T (2014)	1
TRIM27	2	PIAS2	2	affinity chromatography technology, two hybrid	Matsuura T (2005), Matsuura T (2005)	2
NPM1	0	EEF1D	3	affinity chromatography technology	Chen R (2013)	1
RNF2	1	TRIM27	2	affinity chromatography technology	Hein MY (2015)	1
LATS2	1	PARD3	5	affinity chromatography technology, bioid	Couzens AL (2013), Couzens AL (2013)	2
OPRK1	1	SIAH2	0	affinity chromatography technology	Petko J (2013)	1
SIAH1	2	KATNAL1	4	two hybrid	Rolland T (2014)	1
HTT	14	PIAS1	4	two hybrid	Suter B (2013)	1
RARA	5	NPM1	0	affinity chromatography technology	McNamara S (2008)	1
SIAH1	2	UXT	0	two hybrid	Rolland T (2014)	1
NUMBL	1	SIAH1	2	two hybrid	Wang J (2011)	1
UBE2D4	0	RLIM	1	two hybrid	Markson G (2009)	1
SIAH1	2	LACTB2	1	two hybrid	Rolland T (2014)	1
TRIM27	2	MAPKBP1	8	two hybrid	Rolland T (2014)	1
DLD	1	SIAH2	0	affinity chromatography technology	Huttlin EL (2015)	1
ATN1	2	RAD54L2	5	two hybrid	Lim J (2006)	1
SIAH1	2	UBE2E3	0	two hybrid	Matsuzawa SI (2001)	1
TBC1D22B	2	STAT3	0	affinity chromatography technology	Huttlin EL (2017)	1
ATXN7	0	PSMC5	4	biochemical	Matilla A (2001)	1
SH3RF1	1	UBE2D1	0	pull down	Lin DH (2009)	1
SIAH2	0	UBE2D2	0	pull down, pull down, pull down	Szargel R (2009), Avraham E (2005), Rott R (2011)	3
LMNA	2	WDYHV1	0	two hybrid	Dittmer TA (2014)	1
SIAH1	2	RBBP8	1	pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	Germani A (2003), Germani A (2003), Germani A (2003), Liu H (2015)	4
COPS5	0	PUF60	16	affinity chromatography technology	Bennett EJ (2010)	1
TBL1X	1	SIAH1	2	affinity chromatography technology	Matsuzawa SI (2001)	1
TOLLIP	3	PEG10	2	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
COPS5	0	APC	5	affinity chromatography technology	Huang X (2009)	1
STAT3	0	PML	7	affinity chromatography technology, pull down	Kawasaki A (2003), Kawasaki A (2003)	2
PRPF31	0	TFDP1	3	biochemical	Havugimana PC (2012)	1
HIF1AN	0	PSMC5	4	affinity chromatography technology	Rodriguez J (2016)	1
USP19	1	RNF2	1	two hybrid	Velasco K (2013)	1
TRIM27	2	PIAS1	4	two hybrid, affinity chromatography technology	Matsuura T (2005), Matsuura T (2005)	2
SNCAIP	2	SNCA	0	two hybrid, fluorescent resonance energy transfe, two hybrid, pull down, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Neystat M (2002), Kawamata H (2001), Engelender S (1999), Engelender S (1999), Engelender S (1999), Xie YY (2010), Xie YY (2010), Smith WW (2005), Smith WW (2005), Bandopadhyay R (2005), Lee G (2004), Ryo A (2006), Ryo A (2006), Norris KL (2015), Nagano Y (2001)	15
UBE2D1	0	TRIM27	2	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Markson G (2009), Napolitano LM (2011), Napolitano LM (2011), Napolitano LM (2011)	4
COPS5	0	PTPMT1	0	affinity chromatography technology	Bennett EJ (2010)	1
SIAH1	2	KIAA0319L	4	two hybrid	Rolland T (2014)	1
TOLLIP	3	RLIM	1	affinity chromatography technology	Li S (2011)	1
PHC2	3	SPATC1L	0	two hybrid	Rolland T (2014)	1
GRM5	6	SIAH1	2	two hybrid, affinity chromatography technology	Ko SJ (2012), Ko SJ (2012)	2
SIAH1	2	PARD3	5	affinity chromatography technology	Famulski JK (2010)	1
MAP3K5	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AQP1	1	TRIM23	3	two hybrid	Rolland T (2014)	1
SIAH1	2	MTIF3	1	two hybrid	Rolland T (2014)	1
AFF1	1	SIAH1	2	two hybrid, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology	Bursen A (2004), Bursen A (2004), Bursen A (2004), Bursen A (2004), Bursen A (2004)	5
VAV1	2	SIAH2	0	two hybrid, pull down, affinity chromatography technology	Germani A (1999), Germani A (1999), Germani A (1999)	3
LMNA	2	AQP1	1	two hybrid	Dittmer TA (2014)	1
SIAH1	2	ELL2	4	enzymatic study	Liu M (2012)	1
SIAH2	0	TP53BP2	5	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Kim H (2013), Kim H (2013), Kim H (2013), Kim H (2013)	4
SIAH2	0	USP19	1	affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology	Altun M (2012), Altun M (2012), Velasco K (2013), Velasco K (2013)	4
SIAH1	2	PIAS1	4	two hybrid, pull down, affinity chromatography technology	Depaux A (2007), Depaux A (2007), Lee JH (2016)	3
SIAH1	2	RLIM	1	affinity chromatography technology	Kraemer OH (2008)	1
PIAS2	2	PIAS1	4	imaging technique	Chen TC (2014)	1
PML	7	NPM1	0	affinity chromatography technology	McNamara S (2008)	1
TRIM27	2	SIAH1	2	two hybrid	Rolland T (2014)	1
TRIM27	2	SDCBP	0	two hybrid	Rolland T (2014)	1
SIAH2	0	PIAS2	2	two hybrid	Depaux A (2007)	1
AFF4	2	ELL2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu M (2012), Takahashi H (2011), Takahashi H (2011), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
SEPT4	2	SNCA	0	affinity chromatography technology, unspecified method	Ihara M (2003), Woods WS (2007)	2
SIAH1	2	SIAH1	2	pull down, biochemical, enzymatic study, affinity chromatography technology, enzymatic study, x-ray crystallography, affinity chromatography technology, two hybrid, two hybrid, x-ray crystallography, enzymatic study, two hybrid	Matsuzawa S (1998), Susini L (2001), Mei Y (2007), Mei Y (2007), Szargel R (2009), Matsuzawa S (2003), Lee SB (2012), Woodsmith J (2012), Wang J (2011), Rimsa V (2013), Durcan TM (2011), Rolland T (2014)	12
SIAH1	2	NPM1	0	affinity chromatography technology, affinity chromatography technology	Lee SB (2012), Lee SB (2012)	2
PRPF31	0	UBE2N	1	affinity chromatography technology	Boldt K (2016)	1
TRIM27	2	IQCN	0	two hybrid	Rolland T (2014)	1
LMNA	2	SDCBP	0	bioid	Roux KJ (2012)	1
OPRM1	0	SIAH2	0	two hybrid, affinity chromatography technology	Petko J (2013), Petko J (2013)	2
SIAH1	2	OTUB2	0	two hybrid	Rolland T (2014)	1
UBE2D4	0	XIAP	0	two hybrid	Markson G (2009)	1
PIAS1	4	PML	7	affinity chromatography technology, affinity chromatography technology, enzymatic study	Rabellino A (2012), Rabellino A (2012), Rabellino A (2012)	3
HTT	14	UBE2K	0	two hybrid, two hybrid, pull down, two hybrid	Faber PW (1998), Kalchman MA (1996), Kalchman MA (1996), Suter B (2013)	4
SDCBP	0	ZCCHC10	0	two hybrid	Rolland T (2014)	1
UBE2I	0	PML	7	enzymatic study, pull down, enzymatic study, two hybrid, two hybrid, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, pull down	Knipscheer P (2008), Kim YE (2005), Satow R (2012), Duprez E (1999), Wang J (2011), Tatham MH (2003), Duprez E (1999), Gocke CB (2005), Lin DY (2006), Jo S (2016), Schilling EM (2017)	11
MYD88	1	SIAH1	2	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
HIPK3	5	SIAH2	0	two hybrid	Colland F (2004)	1
SIAH2	0	SH3RF1	1	two hybrid, affinity chromatography technology	Christian PA (2011), Christian PA (2011)	2
UBE2D1	0	TRIM8	6	two hybrid	Markson G (2009)	1
CTNNB1	30	CACYBP	0	affinity chromatography technology, affinity chromatography technology, imaging technique	Matsuzawa SI (2001), Wang D (2011), Chen TC (2014)	3
NUMB	1	TERF2	2	two hybrid	Grossmann A (2015)	1
RUNX1	0	PML	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Kraemer OH (2008), Nguyen LA (2005), Nguyen LA (2005), Nguyen LA (2005), Nguyen LA (2005)	5
SIAH1	2	AASDHPPT	0	two hybrid	Rolland T (2014)	1
KCNJ10	0	BAG1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HIPK3	5	SIAH1	2	two hybrid	Colland F (2004)	1
SIAH1	2	MAP3K5	1	affinity chromatography technology, pull down, enzymatic study	Tristan CA (2015), Tristan CA (2015), Tristan CA (2015)	3
TBL1X	1	UBE2E3	0	affinity chromatography technology	Choi HK (2008)	1
SDCBP	0	SIAH1	2	two hybrid	Rolland T (2014)	1
PEG3	2	SIAH1	2	affinity chromatography technology, two hybrid	Relaix F (2000), Relaix F (2000)	2
LMNA	2	CTNNB1	30	affinity chromatography technology	Choi J (2004)	1
PYGB	3	SIAH1	2	two hybrid	Rolland T (2014)	1
DAB1	1	PRR20A	0	two hybrid	Rolland T (2014)	1
COPS5	0	GAPDH	0	affinity chromatography technology	Bennett EJ (2010)	1
SIAH1	2	DNALI1	0	two hybrid	Rolland T (2014)	1
AQP1	1	TNK2	7	two hybrid	Rolland T (2014)	1
DLD	1	AASDHPPT	0	affinity chromatography technology	Malty RH (2017)	1
APC	5	EEF1D	3	affinity chromatography technology	Hein MY (2015)	1
SIAH1	2	SH3RF1	1	affinity chromatography technology, affinity chromatography technology	Xu Z (2006), Xu Z (2006)	2
HTT	14	SIAH1	2	affinity chromatography technology	Bae BI (2006)	1
UBE2I	0	PIAS3	2	two hybrid, two hybrid	Bandyopadhyay S (2010), Wang J (2011)	2
HTT	14	CTNNB1	30	affinity chromatography technology	Godin JD (2010)	1
SIAH1	2	RAD51AP1	1	two hybrid	Rolland T (2014)	1
SIAH1	2	VAV1	2	two hybrid	Germani A (1999)	1
CACYBP	0	USP19	1	biochemical	Wan C (2015)	1
TRIM23	3	UBE2N	1	pull down	Dawidziak DM (2017)	1
SIAH1	2	ZBP1	2	two hybrid	Rolland T (2014)	1
MAPK12	1	SIAH1	2	two hybrid	Rolland T (2014)	1
NPM1	0	TXN	1	affinity chromatography technology	Chen R (2013)	1
SDCBP	0	PUF60	16	two hybrid	Rolland T (2014)	1
SNCAIP	2	SIAH1	2	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down	Liani E (2004), Liani E (2004), Liani E (2004), Liani E (2004), Nagano Y (2003), Nagano Y (2003), Nagano Y (2003)	7
SNCAIP	2	HERPUD1	2	affinity chromatography technology, affinity chromatography technology	Miura H (2010), Miura H (2010)	2
SIAH1	2	PRPF31	0	two hybrid	Rolland T (2014)	1
UBE2K	0	UBE2N	1	biochemical	Wan C (2015)	1
SIAH1	2	UBE2I	0	two hybrid, two hybrid	Depaux A (2007), Hu G (1997)	2
UBE2D1	0	XIAP	0	two hybrid, affinity chromatography technology, two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Markson G (2009), Hu S (2003), Dynek JN (2010), Morizane Y (2005), Janzer A (2012), Liu WH (2007), Takeda AN (2014), Markson G (2009), Hao Y (2004), Hanson AJ (2012)	10
SIAH1	2	TXN	1	two hybrid	Wang J (2011)	1
LATS2	1	CTNNB1	30	bioid, affinity chromatography technology, affinity chromatography technology, pull down	Couzens AL (2013), Li J (2013), Li J (2013), Li J (2013)	4
CDC34	3	UBE2D3	1	affinity chromatography technology, affinity chromatography technology	Kuang P (2016), Kuang P (2016)	2
UBE2D4	0	TRIM8	6	two hybrid	Markson G (2009)	1
CDC34	3	TBL1X	1	enzymatic study	Perissi V (2004)	1
ATXN7	0	TRIM23	3	two hybrid	Kahle JJ (2011)	1
UBE2D4	0	TRIM27	2	two hybrid, two hybrid	Markson G (2009), Napolitano LM (2011)	2
DAB1	1	TOLLIP	3	two hybrid	Rolland T (2014)	1
SIAH1	2	ZMAT3	0	two hybrid	Rolland T (2014)	1
4985	0	SIAH2	0	affinity chromatography technology	Petko J (2013)	1
TRIM27	2	PIAS3	2	affinity chromatography technology, two hybrid	Matsuura T (2005), Matsuura T (2005)	2
IQCN	0	APC	5	affinity chromatography technology	Huttlin EL (2017)	1
UBE2V2	0	RNF2	1	two hybrid	Markson G (2009)	1
STAT3	0	COPS5	0	affinity chromatography technology	Nishimoto A (2013)	1
CACYBP	0	UBE2I	0	affinity chromatography technology	Wasik U (2013)	1
RUNX1	0	UXT	0	two hybrid, affinity chromatography technology, pull down, two hybrid	McGilvray R (2007), McGilvray R (2007), McGilvray R (2007), McGilvray R (2007)	4
UBE2E2	1	RNF2	1	two hybrid	Markson G (2009)	1
APC	5	SIAH1	2	pull down, affinity chromatography technology, imaging technique	Liu J (2001), Liu J (2001), Chen TC (2014)	3
UBE2I	0	PUF60	16	two hybrid	Rolland T (2014)	1
MCM2	3	UBE2D2	0	affinity chromatography technology	Drissi R (2015)	1
KLF10	1	SIAH1	2	two hybrid, affinity chromatography technology, pull down	Johnsen SA (2002), Johnsen SA (2002), Lin CH (2015)	3
TBL1X	1	CACYBP	0	affinity chromatography technology, imaging technique	Matsuzawa SI (2001), Chen TC (2014)	2
TXN	1	UBE2K	0	biochemical	Havugimana PC (2012)	1
JSRP1	1	SIAH1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HIPK2	0	SIAH2	0	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Calzado MA (2009), Calzado MA (2009), Calzado MA (2009), Calzado MA (2009), Lee MG (2014)	5
ATN1	2	SIAH2	0	two hybrid	Lim J (2006)	1
MYD88	1	TXN	1	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
TBC1D22B	2	CAPG	3	affinity chromatography technology	Huttlin EL (2017)	1
UBE2D2	0	TRIM8	6	two hybrid, pull down	Markson G (2009), Li Q (2011)	2
UBE2D4	0	SIAH1	2	two hybrid	van Wijk SJ (2009)	1
SIAH1	2	DNAJC15	0	two hybrid	Rolland T (2014)	1
TRIM27	2	CCDC198	0	two hybrid	Rolland T (2014)	1
SIAH1	2	BAG1	1	pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Matsuzawa S (1998), Matsuzawa S (1998), Matsuzawa S (1998), Matsuzawa S (1998), Matsuzawa S (2003)	5
TP53BP2	5	PRPF31	0	two hybrid	Rolland T (2014)	1
MCM2	3	GAPDH	0	affinity chromatography technology	Drissi R (2015)	1
PML	7	SIAH2	0	affinity chromatography technology, affinity chromatography technology, pull down	Fanelli M (2004), Fanelli M (2004), Fanelli M (2004)	3
PUF60	16	QRICH1	8	two hybrid	Rolland T (2014)	1
PML	7	CTNNB1	30	affinity chromatography technology, pull down, affinity chromatography technology	Satow R (2012), Satow R (2012), Shtutman M (2002)	3
SIAH1	2	RAB33A	0	two hybrid	Rolland T (2014)	1
RNF2	1	NOL6	2	affinity chromatography technology	Cao Q (2014)	1
BCL6	6	KIFC3	3	two hybrid	Rolland T (2014)	1
CTNNB1	30	COPS5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang X (2009), Jumpertz S (2014), Jumpertz S (2014)	3
CTNNB1	30	BCL6	6	pull down	Kotlyar M (2015)	1
TRIM23	3	UBE2D2	0	pull down, pull down, pull down	Vichi A (2005), Vichi A (2006), Dawidziak DM (2017)	3
SNCA	0	HERPUD1	2	affinity chromatography technology, affinity chromatography technology	Miura H (2010), Miura H (2010)	2
PKD1	18	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Geng L (2000), Geng L (2000)	2
UBE2E2	1	TRIM23	3	two hybrid	Markson G (2009)	1
TRIM23	3	SIAH1	2	two hybrid	Rolland T (2014)	1
TRIM7	2	UBE2D1	0	two hybrid	Napolitano LM (2011)	1
OPRK1	1	SIAH1	2	affinity chromatography technology	Petko J (2013)	1
MAB21L1	0	SIAH1	2	two hybrid	Rolland T (2014)	1
UBE2D2	0	TRIM27	2	two hybrid, two hybrid	Markson G (2009), Napolitano LM (2011)	2
DAB1	1	WDYHV1	0	two hybrid	Rolland T (2014)	1
PHC1	1	SIAH1	2	two hybrid	Rolland T (2014)	1
UBE2N	1	XIAP	0	two hybrid, pull down	Markson G (2009), Markson G (2009)	2
SIAH2	0	PLCE1	2	affinity chromatography technology, pull down, affinity chromatography technology	Yun S (2008), Yun S (2008), Yun S (2008)	3
OPRM1	0	SIAH1	2	two hybrid, pull down, affinity chromatography technology	Petko J (2013), Petko J (2013), Petko J (2013)	3
TRIM27	2	ZFYVE21	0	two hybrid	Rolland T (2014)	1
OPRM1	0	COPS5	0	two hybrid, pull down, pull down, affinity chromatography technology	Petko J (2013), Petko J (2013), Petko J (2013), Petko J (2013)	4
TP53BP2	5	OTUB2	0	two hybrid	Rolland T (2014)	1
COPS5	0	HIST4H4	1	affinity chromatography technology	Bennett EJ (2010)	1
PHC1	1	UBE2I	0	two hybrid	Rual JF (2005)	1
GAPDH	0	TXN	1	affinity chromatography technology	Ewing RM (2007)	1
NPM1	0	PYGB	3	affinity chromatography technology	Chen R (2013)	1
PUF60	16	IQCN	0	two hybrid	Rolland T (2014)	1
SIAH1	2	KIF1B	1	two hybrid	Rolland T (2014)	1
RNF2	1	EEF1D	3	affinity chromatography technology	Cao Q (2014)	1
DAB1	1	ZCCHC10	0	two hybrid	Rolland T (2014)	1
TERF2	2	ATN1	2	affinity chromatography technology	Giannone RJ (2010)	1
UBE2I	0	KIF1B	1	affinity chromatography technology	Hein MY (2015)	1
COPS5	0	PRPF31	0	affinity chromatography technology	Bennett EJ (2010)	1
CDC34	3	SDCBP	0	two hybrid	Rolland T (2014)	1
KIFC3	3	SIAH1	2	two hybrid	Rolland T (2014)	1
SIAH1	2	SNCA	0	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Lee JT (2008), Lee JT (2008), Rott R (2008), Rott R (2008), Szargel R (2009), Szargel R (2009), Szargel R (2009), Szargel R (2009), Szargel R (2016)	9
NPM1	0	PSMC5	4	affinity chromatography technology	Chen R (2013)	1
EEF1D	3	LMNA	2	biochemical	Kristensen AR (2012)	1
RNF2	1	TFDP1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Hauri S (2016), Hauri S (2016)	3
FLI1	2	UBE2I	0	two hybrid	van den Akker E (2005)	1
SIAH1	2	PSMC6	0	affinity chromatography technology	Kulikov R (2010)	1
TOLLIP	3	WDYHV1	0	two hybrid	Rolland T (2014)	1
UBE2D3	1	RLIM	1	two hybrid	Markson G (2009)	1
UBE2K	0	TRIM27	2	two hybrid	Markson G (2009)	1
PML	7	SIAH1	2	affinity chromatography technology	Kraemer OH (2008)	1
SIAH1	2	HIPK1	1	affinity chromatography technology	Kim SY (2009)	1
SIAH1	2	PHC2	3	affinity chromatography technology, pull down, two hybrid, two hybrid, two hybrid	Wu H (2010), Wu H (2010), Wang J (2011), Rolland T (2014), Yu H (2011)	5
MCM2	3	TXN	1	affinity chromatography technology	Drissi R (2015)	1
BCL6	6	TRIB3	0	affinity chromatography technology	Miles RR (2005)	1
RUNX1	0	RARA	5	affinity chromatography technology	Kraemer OH (2008)	1
SIAH1	2	ZCCHC13	0	two hybrid	Rolland T (2014)	1
HTT	14	PSMC5	4	affinity chromatography technology, pull down	Rousseau E (2009), Rousseau E (2009)	2
KIFC3	3	TRIM27	2	two hybrid	Rolland T (2014)	1
TRIM7	2	UBE2D3	1	two hybrid	Napolitano LM (2011)	1
MCM2	3	PUF60	16	affinity chromatography technology	Drissi R (2015)	1
SIAH1	2	CCDC198	0	two hybrid	Rolland T (2014)	1
SIAH1	2	ARMC9	4	two hybrid	Rolland T (2014)	1
SIAH1	2	TOLLIP	3	two hybrid	Rolland T (2014)	1
SIAH1	2	RUNX1	0	affinity chromatography technology, affinity chromatography technology	Kraemer OH (2008), Kraemer OH (2008)	2
PML	7	RARA	5	pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhong S (1999), Zhong S (1999), Minucci S (2000), Kraemer OH (2008), Wang K (2010), Wang K (2010), Cote S (2000), Bellodi C (2006), Villa R (2007)	9
PSMC5	4	PSMC6	0	pull down, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology	Hartmann-Petersen R (2001), Lee SH (2012), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017)	6
SIAH1	2	DLD	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PHC2	3	PRPF31	0	two hybrid	Rolland T (2014)	1
MAPRE3	0	SIAH1	2	pull down, enzymatic study	Ban R (2009), Ban R (2009)	2
PFKM	4	SIAH1	2	two hybrid	Rolland T (2014)	1
LMNA	2	PML	7	bioid	Roux KJ (2012)	1
SIAH1	2	PUF60	16	two hybrid, two hybrid, two hybrid, two hybrid	Buchwald M (2012), Wang J (2011), Rolland T (2014), Yu H (2011)	4
TRIM27	2	PTPMT1	0	two hybrid	Rolland T (2014)	1
TRIM27	2	WDYHV1	0	two hybrid	Rolland T (2014)	1
PML	7	HTT	14	pull down, pull down	Guo L (2014), Guo L (2014)	2
UBE2I	0	ATXN7	0	affinity chromatography technology	Janer A (2010)	1
LMNA	2	NPM1	0	affinity chromatography technology	Depreux FF (2015)	1
UBE2E2	1	SIAH1	2	pull down, affinity chromatography technology, affinity chromatography technology	Kraemer OH (2008), Kraemer OH (2008), Lee JT (2008)	3
RNF2	1	SIAH1	2	affinity chromatography technology	Woodsmith J (2012)	1
TOLLIP	3	HERPUD1	2	two hybrid	Bandyopadhyay S (2010)	1
UBE2I	0	UBE2K	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, biochemical	Knipscheer P (2008), Gruenwald M (2011), Pichler A (2005), Galisson F (2011), Wan C (2015)	5
SIAH1	2	CDC23	3	two hybrid	Rolland T (2014)	1
TRIM27	2	UBE2E3	0	two hybrid, two hybrid	Napolitano LM (2011), Napolitano LM (2011)	2
TOLLIP	3	PRR20A	0	two hybrid	Rolland T (2014)	1
SIAH2	0	STAT3	0	two hybrid	Wang J (2011)	1
4985	0	SIAH1	2	affinity chromatography technology	Petko J (2013)	1
PEG10	2	SIAH2	0	two hybrid, pull down	Okabe H (2003), Okabe H (2003)	2
TRIM27	2	PRPF31	0	two hybrid	Rolland T (2014)	1
UBE2I	0	HIPK1	1	two hybrid	Bandyopadhyay S (2010)	1
UBE2E2	1	RLIM	1	two hybrid, affinity chromatography technology	Markson G (2009), Kraemer OH (2008)	2
UBE2I	0	TBL1X	1	enzymatic study	Tan M (2015)	1
RNF2	1	PEG10	2	affinity chromatography technology	Voncken JW (2003)	1
RNF2	1	UBE2D1	0	enzymatic study, two hybrid	Lee SJ (2001), Markson G (2009)	2
CTNNB1	30	UBE2D1	0	pull down	Saha A (2008)	1
UBE2I	0	TRIM23	3	two hybrid, two hybrid, two hybrid	Markson G (2009), Rolland T (2014), Yu H (2011)	3
SNCA	0	GAPDH	0	two hybrid, pull down	Vinayagam A (2011), Tsuchiya K (2005)	2
INHA	2	SIAH1	2	two hybrid	Rolland T (2014)	1
UBE2L6	0	TRIM8	6	two hybrid	Markson G (2009)	1
HIPK2	0	PML	7	affinity chromatography technology, enzymatic study, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study	de la Vega L (2011), Renner F (2010), Sung KS (2011), Sung KS (2011), Gresko E (2009), Gresko E (2009), Gresko E (2009)	7
SIAH1	2	PTPMT1	0	two hybrid	Rolland T (2014)	1
HTT	14	DNALI1	0	two hybrid	Goehler H (2004)	1
MCM2	3	UBE2D3	1	affinity chromatography technology	Drissi R (2015)	1
COPS5	0	RPL27A	0	affinity chromatography technology	Bennett EJ (2010)	1
PHC1	1	PHC2	3	two hybrid, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Gunster MJ (1997), Gunster MJ (1997), Gunster MJ (1997), Gao Z (2012), Gao Z (2012), Voncken JW (2005), Huttlin EL (2017)	8
PRR20E	0	SIAH1	2	affinity chromatography technology	Huttlin EL (2017)	1
HIF1AN	0	PFKM	4	affinity chromatography technology	Rodriguez J (2016)	1
UBE2I	0	UBE2D2	0	biochemical	Wan C (2015)	1
UBE2D2	0	XIAP	0	two hybrid, two hybrid, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, pull down, pull down	Markson G (2009), Dynek JN (2010), Nakatani Y (2012), Nakatani Y (2012), Markson G (2009), Fang S (2001), Hu S (2003), Buetow L (2015), Foglizzo M (2016), Edison N (2017)	10
OTUB2	0	TRIM8	6	two hybrid	Hayes SD (2012)	1
TRIM27	2	TRIM23	3	two hybrid, two hybrid	Reymond A (2001), Woodsmith J (2012)	2
RAD54L2	5	UBE2I	0	two hybrid	Domanskyi A (2006)	1
SIAH1	2	HIST4H4	1	two hybrid	Rolland T (2014)	1
ZNF512B	2	KLF10	1	two hybrid	Colland F (2004)	1
RUNX1	0	HIPK2	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Aikawa Y (2006), Aikawa Y (2006), Aikawa Y (2006)	3
TRIM23	3	FAM90A1	1	two hybrid	Rolland T (2014)	1
TRIM27	2	PML	7	affinity chromatography technology	Cao T (1998)	1
DLD	1	PSMC5	4	affinity chromatography technology	Malty RH (2017)	1
MCM2	3	HIST4H4	1	affinity chromatography technology	Drissi R (2015)	1
UBE2D3	1	RNF2	1	two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down	Markson G (2009), Bentley ML (2011), Li Z (2006), Pan MR (2011), Zhang Y (2014), Xia P (2014), Gearhart MD (2006), McGinty RK (2014), Cao Q (2014), Gao Z (2014)	10
TERF2	2	SIAH1	2	pull down, enzymatic study	Fujita K (2010), Fujita K (2010)	2
UBE2L6	0	RUNX1	0	pull down	Kraemer OH (2008)	1
DLD	1	TXN	1	affinity chromatography technology	Malty RH (2017)	1
XIAP	0	UBE2I	0	two hybrid, two hybrid	Dynek JN (2010), Dynek JN (2010)	2
UBE2D4	0	RNF2	1	two hybrid	Markson G (2009)	1
TRIM23	3	KIFC3	3	two hybrid	Rolland T (2014)	1
UBE2K	0	SIAH1	2	two hybrid, two hybrid	Markson G (2009), Rolland T (2014)	2
MCM2	3	PYGB	3	affinity chromatography technology	Drissi R (2015)	1
TP53BP2	5	PARD3	5	affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique	Hauri S (2013), Gen Y (2017), Gen Y (2017), Gen Y (2017)	4
SIAH1	2	EEF1D	3	pull down, affinity chromatography technology, two hybrid, two hybrid	Wu H (2011), Wu H (2011), Wang J (2011), Rolland T (2014)	4
TXN	1	UBE2D2	0	biochemical	Havugimana PC (2012)	1
LMNA	2	TMEM43	1	two hybrid	Dittmer TA (2014)	1
UBE2I	0	HIPK2	0	two hybrid, two hybrid, two hybrid, pull down, two hybrid, enzymatic study	Lee BH (2003), Bandyopadhyay S (2010), Sung KS (2005), Sung KS (2005), Hofmann TG (2005), Sung KS (2005)	6
SIAH1	2	HERPUD1	2	affinity chromatography technology, affinity chromatography technology	Miura H (2010), Miura H (2010)	2
SH3RF1	1	UBE2N	1	pull down, pull down	Votteler J (2009), Tuvia S (2007)	2
OPRM1	0	4985	0	affinity chromatography technology, affinity chromatography technology	Gomes I (2000), He SQ (2011)	2
SIAH1	2	ZFYVE21	0	two hybrid	Rolland T (2014)	1
MCM2	3	SIAH2	0	affinity chromatography technology	Drissi R (2015)	1
SIAH1	2	TNK2	7	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid	Buchwald M (2012), Buchwald M (2012), Buchwald M (2012), Wang J (2011)	4
ATXN7	0	SIAH1	2	two hybrid	Kahle JJ (2011)	1
SIAH1	2	KIF22	1	two hybrid, pull down, pull down, affinity chromatography technology	Germani A (2000), Germani A (2000), Germani A (2000), Germani A (2000)	4
SIAH1	2	PLCE1	2	affinity chromatography technology	Yun S (2008)	1
SIAH1	2	WDYHV1	0	two hybrid	Rolland T (2014)	1
RNF2	1	RPL27A	0	affinity chromatography technology	Cao Q (2014)	1
HTT	14	UBE2E3	0	two hybrid	Suter B (2013)	1
SIAH2	0	LATS2	1	affinity chromatography technology, affinity chromatography technology	Ma B (2016), Ma B (2016)	2
UBE2D1	0	UBE2D2	0	biochemical	Havugimana PC (2012)	1
DLD	1	UBE2N	1	affinity chromatography technology	Malty RH (2017)	1
MX1	0	PIAS1	4	two hybrid, two hybrid	Engelhardt OG (2001), Brantis-de-Carvalho CE (2015)	2
SIAH1	2	PIAS3	2	pull down	Depaux A (2007)	1
SIAH1	2	CACYBP	0	two hybrid, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, two hybrid, x-ray crystallography, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, imaging technique	Matsuzawa SI (2001), Matsuzawa SI (2001), Matsuzawa SI (2001), Dimitrova YN (2010), Santelli E (2005), Santelli E (2005), Santelli E (2005), Santelli E (2005), Matsuzawa S (2003), Matsuzawa S (2003), Ning X (2012), Buchwald M (2012), Chen TC (2014)	13
ATN1	2	GAPDH	0	two hybrid	Lim J (2006)	1
ATXN7	0	PSMC6	0	biochemical	Matilla A (2001)	1
XIAP	0	UBE2L6	0	affinity chromatography technology	Hu S (2003)	1
UBE2E3	0	RNF2	1	two hybrid	Markson G (2009)	1
ZNF512B	2	PEG10	2	two hybrid	Colland F (2004)	1
SIAH1	2	MAPKBP1	8	two hybrid	Rolland T (2014)	1
SIAH1	2	IQCN	0	two hybrid	Rolland T (2014)	1
MX1	0	SIAH1	2	two hybrid	Rolland T (2014)	1
UBE2D3	1	TRIM8	6	two hybrid	Markson G (2009)	1
BAG1	1	TRIM27	2	two hybrid	Rolland T (2014)	1
ATN1	2	SIAH1	2	two hybrid, two hybrid	Lim J (2006), Wang J (2011)	2
MCM2	3	EEF1D	3	affinity chromatography technology	Drissi R (2015)	1
SIAH1	2	ZNF148	4	two hybrid	Rolland T (2014)	1
HIF1AN	0	QRICH1	8	affinity chromatography technology	Rodriguez J (2016)	1
POU2AF1	1	SIAH1	2	two hybrid, affinity chromatography technology, pull down, genetic interference, two hybrid, affinity chromatography technology, pull down	Tiedt R (2001), Tiedt R (2001), Tiedt R (2001), Tiedt R (2001), Boehm J (2001), Boehm J (2001), Boehm J (2001)	7
AFF1	1	NPM1	0	affinity chromatography technology	Benedikt A (2011)	1
AFF1	1	AFF4	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yokoyama A (2010), Yokoyama A (2010), Yokoyama A (2010), Yokoyama A (2010), Takahashi H (2011)	5
LATS2	1	APC	5	bioid	Couzens AL (2013)	1
ATXN7	0	TRIM27	2	two hybrid	Kahle JJ (2011)	1
SIAH1	2	ZNF671	0	two hybrid	Rolland T (2014)	1
PHC1	1	PIAS2	2	two hybrid	Rolland T (2014)	1
SIAH2	0	UBE2D1	0	pull down, pull down, pull down	Rott R (2008), Uchiki T (2009), Fan L (2015)	3
TRIM23	3	TBC1D22B	2	two hybrid	Rolland T (2014)	1
SIAH1	2	DDX41	4	two hybrid	Rolland T (2014)	1
MCM2	3	UBE2D4	0	affinity chromatography technology	Drissi R (2015)	1
SIAH1	2	SYP	0	enzymatic study	Zhao Y (2015)	1
AQP1	1	SIAH1	2	two hybrid	Rolland T (2014)	1
COPS5	0	TXN	1	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Bennett EJ (2010), Hwang CY (2004), Hwang CY (2004), Hwang CY (2004), Hwang CY (2004), Hwang CY (2004)	6
NPM1	0	RPL27A	0	affinity chromatography technology	Hein MY (2015)	1
TRIM8	6	PIAS3	2	affinity chromatography technology	Okumura F (2010)	1
UBE2K	0	UBE2D2	0	biochemical	Wan C (2015)	1
HIPK2	0	SIAH1	2	two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Calzado MA (2009), Calzado MA (2009), Calzado MA (2009), Calzado MA (2009), Calzado MA (2009), Winter M (2008), Winter M (2008), Winter M (2008), Kim SY (2009), Kim SY (2009), Kim SY (2009), Kim SY (2009), Kurokawa K (2013)	13
RBBP8	1	WDYHV1	0	two hybrid	Rual JF (2005)	1
TXN	1	MAP3K5	1	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu Y (2002), Liu Y (2002), Morita K (2001), Saitoh M (1998), Saitoh M (1998), Saitoh M (1998), Fujino G (2007), Fujino G (2007), Goerner K (2007), Im JY (2010), Im JY (2010), Junn E (2000), Yu Y (2013), Yamawaki H (2005), Matsuoka S (2008), Hwang SG (2014), Yoon KW (2009)	17
SIAH1	2	TBC1D22B	2	two hybrid	Rolland T (2014)	1
UBE2I	0	PIAS2	2	two hybrid, two hybrid, two hybrid, pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down	Rual JF (2005), Lee BH (2003), Bandyopadhyay S (2010), Schmidt D (2002), Wang J (2011), Rolland T (2014), Saul VV (2014), van den Akker E (2005), Schmidt D (2002)	9
SIAH1	2	FAM90A1	1	two hybrid	Rolland T (2014)	1
UBE2I	0	HIPK3	5	two hybrid	Bandyopadhyay S (2010)	1
TRIM23	3	PIAS2	2	two hybrid	Rolland T (2014)	1
TRIM23	3	UBE2D3	1	pull down, pull down, pull down	Vichi A (2005), Vichi A (2006), Dawidziak DM (2017)	3
SIAH2	0	UBE2D3	1	pull down	Stebbins JL (2013)	1
BAG1	1	RARA	5	pull down, two hybrid	Liu R (1998), Liu R (1998)	2
TERF2	2	PIAS1	4	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Her J (2015), Her J (2015), Her J (2015), Her J (2015)	4
TRIM27	2	SPATC1L	0	two hybrid	Rolland T (2014)	1
SIAH2	0	SNCAIP	2	enzymatic study	Avraham E (2005)	1
SIAH1	2	SIAH2	0	affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Depaux A (2006), Depaux A (2006), Depaux A (2006), Huttlin EL (2017)	5
XIAP	0	TRIM8	6	two hybrid	Woodsmith J (2012)	1
SIAH1	2	SYT7	4	two hybrid	Rolland T (2014)	1
DCC	3	SIAH1	2	pull down	Hu G (1999)	1
TRIB3	0	SIAH1	2	two hybrid, affinity chromatography technology, affinity chromatography technology	Zhou Y (2008), Zhou Y (2008), Zhou Y (2008)	3
SIAH1	2	NOL6	2	two hybrid	Rolland T (2014)	1
SIAH1	2	PIAS2	2	two hybrid	Depaux A (2007)	1
SIAH1	2	KIAA1217	7	two hybrid	Rolland T (2014)	1
SIAH1	2	ZCCHC10	0	two hybrid	Rolland T (2014)	1
MCM2	3	UBE2L6	0	affinity chromatography technology	Drissi R (2015)	1
OPRM1	0	HTT	14	affinity chromatography technology	Huttlin EL (2017)	1
SIAH1	2	NUMB	1	two hybrid, pull down, pull down, affinity chromatography technology, two hybrid	Susini L (2001), Susini L (2001), Susini L (2001), Susini L (2001), Wang J (2011)	5
SIAH1	2	CTNNB1	30	enzymatic study, affinity chromatography technology, affinity chromatography technology	Dimitrova YN (2010), Jumpertz S (2014), Shin M (2016)	3
UBE2L6	0	TRIM27	2	two hybrid	Markson G (2009)	1
RNF2	1	PHC1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Gao Z (2012), Hein MY (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	6
KCNJ10	0	SIAH1	2	two hybrid	Rolland T (2014)	1
MOB3C	2	LATS2	1	pull down	Chow A (2010)	1
DAB1	1	SIAH1	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid	Park TJ (2003), Park TJ (2003), Park TJ (2003), Park TJ (2003), Park TJ (2003)	5
ELL2	4	AFF1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Takahashi H (2011), Lu H (2014), Hein MY (2015)	3
SIAH1	2	HIF1AN	0	affinity chromatography technology	Fukuba H (2008)	1
SIAH1	2	XIAP	0	affinity chromatography technology, affinity chromatography technology	Garrison JB (2011), Garrison JB (2011)	2
SH3RF1	1	HERPUD1	2	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Tuvia S (2007), Tuvia S (2007), Tuvia S (2007), Tuvia S (2007), Tuvia S (2007)	5
RNF2	1	HIST4H4	1	affinity chromatography technology, affinity chromatography technology	Trojer P (2011), Cao Q (2014)	2
UBE2L6	0	SIAH1	2	pull down	Kraemer OH (2008)	1
LATS2	1	SIAH1	2	affinity chromatography technology, affinity chromatography technology	Xiang L (2014), Xiang L (2014)	2
PARD3	5	CTNNB1	30	imaging technique	Chen TC (2014)	1
PIAS2	2	PML	7	imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study	Cuchet-Lourenco D (2011), Rabellino A (2012), Rabellino A (2012), Rabellino A (2012)	4
UBE2D2	0	RLIM	1	two hybrid	Markson G (2009)	1
UBE2E2	1	XIAP	0	two hybrid	Markson G (2009)	1
EXOC3L2	2	SIAH1	2	affinity chromatography technology	Huttlin EL (2017)	1
TOLLIP	3	XIAP	0	affinity chromatography technology	Li S (2011)	1
RAD54L2	5	PIAS1	4	pull down	Ogawa H (2009)	1
XIAP	0	WDYHV1	0	two hybrid	Rual JF (2005)	1
TRIM27	2	TBC1D22B	2	two hybrid	Rolland T (2014)	1
SIAH1	2	TRIM8	6	two hybrid	Woodsmith J (2012)	1
SIAH1	2	TP53BP2	5	two hybrid, two hybrid	Wang J (2011), Rolland T (2014)	2
UBE2I	0	TRIM27	2	two hybrid, affinity chromatography technology	Markson G (2009), Chu Y (2011)	2
MCM2	3	UBE2D1	0	affinity chromatography technology	Drissi R (2015)	1
LMNA	2	PIAS2	2	two hybrid	Dittmer TA (2014)	1
SIAH1	2	PRR20A	0	two hybrid	Rolland T (2014)	1
MCM2	3	SIAH1	2	affinity chromatography technology	Drissi R (2015)	1
COPS5	0	SIAH1	2	affinity chromatography technology	Jumpertz S (2014)	1
RPL27A	0	SIAH1	2	two hybrid	Rolland T (2014)	1
SIAH1	2	TRIM7	2	two hybrid	Rolland T (2014)	1
DCC	3	SIAH2	0	two hybrid	Hu G (1997)	1
SIAH2	0	RBBP8	1	pull down	Germani A (2003)	1
TRIM23	3	116349	0	two hybrid	Rolland T (2014)	1
DLD	1	PSMC6	0	affinity chromatography technology	Malty RH (2017)	1
SH3RF1	1	UBE2D3	1	pull down, pull down	Votteler J (2009), Tuvia S (2007)	2
RARA	5	SIAH1	2	affinity chromatography technology	Kraemer OH (2008)	1
SIAH1	2	RPS19BP1	0	two hybrid	Rolland T (2014)	1
PHC2	3	SDCBP	0	two hybrid	Rolland T (2014)	1
ATXN7	0	TP53BP2	5	two hybrid	Lim J (2006)	1
USP19	1	XIAP	0	affinity chromatography technology, affinity chromatography technology	Mei Y (2011), Mei Y (2011)	2
SIAH1	2	TMEM43	1	two hybrid	Rolland T (2014)	1
UBE2D2	0	SIAH1	2	two hybrid, two hybrid, pull down, pull down	van Wijk SJ (2009), Markson G (2009), Szargel R (2009), Winter M (2008)	4
RNF2	1	PHC2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Gao Z (2012), Voncken JW (2005), Cao Q (2014), Hein MY (2015), Hauri S (2016), Hauri S (2016)	7
SIAH1	2	FLT3	5	pull down, affinity chromatography technology	Buchwald M (2010), Buchwald M (2010)	2
SIAH2	0	UBE2I	0	two hybrid, two hybrid, two hybrid	Depaux A (2007), Hu G (1997), Wang J (2011)	3
SIAH1	2	ZNF512B	2	two hybrid	Rolland T (2014)	1
SIAH1	2	SPATA4	1	two hybrid	Rolland T (2014)	1
UBE2D3	1	XIAP	0	two hybrid, affinity chromatography technology, two hybrid, pull down, pull down, pull down, pull down	Markson G (2009), Hu S (2003), Dynek JN (2010), Bartke T (2004), Bornstein B (2011), Damgaard RB (2013), Markson G (2009)	7
UBE2I	0	LMNA	2	two hybrid, affinity chromatography technology, enzymatic study	Zhong N (2005), Zhong N (2005), Matafora V (2009)	3
TRIM23	3	UBE2D4	0	pull down	Dawidziak DM (2017)	1
USP19	1	SIAH1	2	two hybrid, two hybrid, affinity chromatography technology, x-ray crystallography, pull down, unspecified method	Altun M (2012), Velasco K (2013), Velasco K (2013), Zhang Q (2017), Zhang Q (2017), Zhang Q (2017)	6
NPM1	0	NOL6	2	affinity chromatography technology	Hein MY (2015)	1
SIAH1	2	GDPD5	1	two hybrid	Rolland T (2014)	1
SIAH1	2	STAT3	0	two hybrid, affinity chromatography technology	Wang J (2011), Shin M (2016)	2
LATS2	1	TP53BP2	5	bioid	Couzens AL (2013)	1
SEPT4	2	XIAP	0	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, protein complementation assay	Garrison JB (2011), Garrison JB (2011), Bornstein B (2011), Bornstein B (2011), Edison N (2012), Gottfried Y (2004), Gottfried Y (2004), Fu RH (2017), Edison N (2017), Edison N (2017), Edison N (2017)	11
CAPG	3	SIAH1	2	two hybrid	Rolland T (2014)	1
UBE2D1	0	TBL1X	1	enzymatic study	Perissi V (2004)	1
OTUB2	0	UBE2N	1	pull down	Nakada S (2010)	1
RAPH1	3	SIAH1	2	two hybrid	Wang J (2011)	1
UBE2I	0	PIAS1	4	two hybrid, pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down	Lee BH (2003), Sapetschnig A (2002), Kahyo T (2001), Bandyopadhyay S (2010), Driscoll JJ (2010), Kahyo T (2001), Yin Y (2012), Gocke CB (2005), van den Akker E (2005), Ogawa H (2009), Schmidt D (2002), Gibbs-Seymour I (2015)	12
FLI1	2	PIAS2	2	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	van den Akker E (2005), van den Akker E (2005), van den Akker E (2005), van den Akker E (2005), van den Akker E (2005)	5
DLD	1	CACYBP	0	affinity chromatography technology	Malty RH (2017)	1
SIAH1	2	NELFA	2	two hybrid	Rolland T (2014)	1
MCM2	3	LMNA	2	affinity chromatography technology	Drissi R (2015)	1
SIAH1	2	QRICH1	8	two hybrid	Rolland T (2014)	1
UBE2V2	0	UBE2N	1	pull down, two hybrid, x-ray crystallography, two hybrid, two hybrid, two hybrid, pull down, pull down, x-ray crystallography, affinity chromatography technology, pull down, two hybrid, pull down, pull down, affinity chromatography technology, two hybrid, pull down, biochemical, x-ray crystallography, pull down, affinity chromatography technology, pull down, x-ray crystallography, biochemical, x-ray crystallography, affinity chromatography technology	Andersen PL (2005), Andersen PL (2005), Markin CJ (2010), Wooff J (2004), Wooff J (2004), Plans V (2006), Wu PY (2003), McKenna S (2003), McKenna S (2003), Zou W (2005), Takeuchi T (2005), Pastushok L (2005), Pastushok L (2005), Pastushok L (2005), Huen MS (2008), Huen MS (2008), Ye Y (2003), Havugimana PC (2012), Moraes TF (2001), Pastushok L (2007), Zou W (2005), McKenna S (2001), Hodge CD (2015), Wan C (2015), Branigan E (2015), Boldt K (2016)	26
UBE2I	0	TERF2	2	enzymatic study	Her J (2015)	1
MCM2	3	CTNNB1	30	affinity chromatography technology	Drissi R (2015)	1
SIAH1	2	RAD54L2	5	two hybrid	Rolland T (2014)	1
UBE2D2	0	AASDHPPT	0	biochemical	Wan C (2015)	1
MCM2	3	RPL27A	0	affinity chromatography technology	Drissi R (2015)	1
UBE2E2	1	TRIM27	2	two hybrid	Napolitano LM (2011)	1