Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
SORT1 rs629301 T hmg coa reductase inhibitors efficacy yes as measured by lesser reductions in LDL-C. These individuals were also more likely to start out with higher LDL-C before treatment. Allele T is associated with decreased response to hmg coa reductase inhibitors in people with Cardiovascular Diseases and Hypercholesterolemia as compared to allele G. 27648687 1448263702