Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
BARD1 rs2070096 A carboplatin efficacy yes When compared to women who received different treatment regimens. Response was defined as likelihood of achieving relapse-free survival. The paper uses the G allele as the reference allele for this SNP, therefore we have assumed that the authors are referring to the negative strand. As a result, we have complemented the alleles to the positive strand. Allele A is associated with decreased response to carboplatin, docetaxel and trastuzumab in women with Breast Neoplasms. 30071039 1449713634
BARD1 rs2229571 C carboplatin efficacy no When compared to women who received different treatment regimens. Response was defined as likelihood of achieving relapse-free survival. As the paper gives the G allele as the reference allele for this SNP, it is assumed that the alleles are presented as being on the positive strand. Allele C is not associated with decreased response to carboplatin, docetaxel and trastuzumab in women with Breast Neoplasms. 30071039 1449713641