Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
PTPN2	rs7234029	G	etanercept	efficacy	no	No significant associations were seen at either six months or two years after the beginning of treatment when response was measured as number of patients in remission or with low disease activity or by EULAR score.	Allele G is not associated with response to etanercept in people with Arthritis, Rheumatoid as compared to allele A.	28107378	1448995977
PTPN2	rs7234029	G	adalimumab	efficacy	no	A significant association between rs7234029 and response to adalimumab as determined by EULAR score was seen at six months after beginning treatment however this significance was lost upon correction for multiple variables. No significant association was seen at two years after beginning treatment. No significant associations were seen at either time point when response was measured as number of patients in remission or with low disease activity.	Allele G is not associated with response to adalimumab in people with Arthritis, Rheumatoid as compared to allele A.	28107378	1448995964