PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
PRKCD	2	DHX16	5	affinity chromatography technology	Hein MY (2015)	1
PDPK1	0	CARD11	4	affinity chromatography technology, affinity chromatography technology, two hybrid	Lee KY (2005), Lee KY (2005), Vinayagam A (2011)	3
TP53	0	TP73	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Stindt MH (2015), Puca R (2011), De Laurenzi V (1998), Di Como CJ (1999)	4
TRIM41	6	PRKCB	4	affinity chromatography technology, pull down, enzymatic study	Chen D (2007), Chen D (2007), Chen D (2007)	3
PRKCD	2	TIAM1	3	enzymatic study	Fleming IN (1999)	1
SHC1	0	HSP90AA1	7	affinity chromatography technology	Brehme M (2009)	1
YWHAZ	1	APP	1	pull down	Olah J (2011)	1
ELAVL1	0	TP53	0	affinity chromatography technology	Galban S (2003)	1
TP53	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Wang C (2003), Akakura S (2001), Peng Y (2001), Nagata Y (1999), Wang J (2011), Burch L (2004), Taipale M (2012), Fogeron ML (2013), Walerych D (2004)	9
MYC	2	SQSTM1	0	affinity chromatography technology	Koch HB (2007)	1
TP53	0	MUC1	0	affinity chromatography technology, pull down, imaging technique	Wei X (2005), Wei X (2005), Wei X (2005)	3
NGEF	1	PRKCD	2	affinity chromatography technology	Huttlin EL (2017)	1
AFAP1	3	PRKCB	4	pull down	Qian Y (2002)	1
TP53	0	ACTBL2	0	affinity chromatography technology	Horikawa I (2014)	1
IL6ST	0	PTPN6	0	affinity chromatography technology	Bartoe JL (2000)	1
IRS1	7	APP	1	pull down	Olah J (2011)	1
IKBKB	1	PRKCD	2	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Lallena MJ (1999), Lallena MJ (1999), Lallena MJ (1999), Lallena MJ (1999)	4
HSPB1	2	FXR1	0	two hybrid	Katsogiannou M (2014)	1
PRKCD	2	SP1	0	affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsai PF (2011), Tsai PF (2011), Tsai PF (2011), Ito H (2012), Xu K (2009), Xu K (2009)	6
HSP90AA1	7	VCP	6	affinity chromatography technology, affinity chromatography technology	Vij N (2006), Yu CC (2013)	2
VHL	0	PRKCD	2	fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Iturrioz X (2006), Iturrioz X (2006), Yong HJ (2017), Yong HJ (2017)	4
TRAF6	0	HSPA4	3	affinity chromatography technology, enzymatic study, affinity chromatography technology	Chen H (2006), Pridgeon JW (2004), Chen H (2006)	3
TP53	0	RANBP9	5	two hybrid	Chen J (2008)	1
SP1	0	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, two hybrid, imaging technique, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Gao J (2009), Goto T (2006), Hung JJ (2006), Hung JJ (2006), Hung JJ (2006), Choi HS (2002), Walker GE (2001), Kundu TK (2000), Suzuki T (2000), Suzuki T (2000), Wang X (2008), Wang X (2008), Wang X (2008), Chen YJ (2007), Chen YJ (2007), Azahri NS (2012), Azahri NS (2012), Li J (2013), Li J (2013), Wang SA (2014)	20
ELAVL1	0	DIABLO	2	affinity chromatography technology	Abdelmohsen K (2009)	1
VCP	6	PHB	0	biochemical	Wan C (2015)	1
PRKCD	2	PDPK1	0	two hybrid, affinity chromatography technology	Hodgkinson CP (2002), Hodgkinson CP (2002)	2
PRKCD	2	DYNC1H1	41	pull down	Rex EB (2010)	1
HDAC5	4	YWHAG	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Carnegie GK (2008), Greco TM (2011), Joshi P (2013)	3
IL6ST	0	STAT3	0	affinity chromatography technology	Novotny-Diermayr V (2002)	1
IKBKB	1	TNFRSF1A	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Zhang SQ (2000), Chaudhary PM (2000), Fan YH (2011), Park KJ (2002), Guan YJ (2011), Guan YJ (2011), Guan YJ (2011), Mitsuhashi S (2008), Chen TC (2014)	9
HSP90AA1	7	PTK2B	6	affinity chromatography technology	Taipale M (2012)	1
PRKCD	2	PLSCR3	0	enzymatic study	Liu J (2003)	1
DYNC1H1	41	RANBP9	5	biochemical	Havugimana PC (2012)	1
HSPB1	2	ZNF131	0	two hybrid	Katsogiannou M (2014)	1
PTPN6	0	PRKCD	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Yoshida K (2001), Yoshida K (2001), Yoshida K (2001), Yoshida K (2001)	4
IL32	1	VHL	0	affinity chromatography technology, affinity chromatography technology	Yong HJ (2017), Yong HJ (2017)	2
PRKCQ	3	MALT1	1	affinity chromatography technology	Shambharkar PB (2007)	1
YWHAG	5	C1QBP	0	affinity chromatography technology	Jin J (2004)	1
PTK2B	6	FYN	1	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Ganju RK (1997), Katagiri T (2000), Qian D (1997), Qian D (1997), Marie-Cardine A (1999)	5
HSP90AA1	7	TRIM41	6	affinity chromatography technology	Taipale M (2012)	1
SNCA	0	HSPA4	3	affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology	Kalia LV (2011), Huang C (2006), Huang C (2006), Lindersson E (2004), Kawakami F (2011), Pemberton S (2011), Klucken J (2006)	7
TRAF6	0	TP53	0	enzymatic study, affinity chromatography technology	Zhang X (2016), Zhang X (2016)	2
VCP	6	YWHAG	5	affinity chromatography technology	Yu CC (2013)	1
HSPB1	2	PTGES3	0	two hybrid	Katsogiannou M (2014)	1
TRAF6	0	PRKCD	2	affinity chromatography technology	Liu Y (2012)	1
RIPK4	0	HSP90AA1	7	affinity chromatography technology	Rodriguez J (2016)	1
IL32	1	PRKCD	2	affinity chromatography technology, affinity chromatography technology	Park YS (2014), Yong HJ (2017)	2
SHC1	0	IL6ST	0	affinity chromatography technology, pull down	Giordano V (1997), Giordano V (1997)	2
YWHAG	5	GSK3A	1	affinity chromatography technology	Jin J (2004)	1
ELAVL1	0	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Abdelmohsen K (2009), Datta K (2005), Datta K (2005), Yuen JS (2007)	4
MYC	2	IRAK1	1	affinity chromatography technology	Koch HB (2007)	1
TNFRSF1A	3	MUC1	0	affinity chromatography technology	Ahmad R (2007)	1
RIPK4	0	PRKCB	4	affinity chromatography technology, enzymatic study	Chen L (2001), Chen L (2001)	2
PPP2CA	7	CARD11	4	enzymatic study	Eitelhuber AC (2011)	1
ITGB2	4	YWHAZ	1	affinity chromatography technology, affinity chromatography technology	Fagerholm S (2002), Fagerholm S (2002)	2
RANBP9	5	TP73	2	pull down, affinity chromatography technology	Kramer S (2005), Kramer S (2005)	2
PHB	0	PRKCD	2	affinity chromatography technology	Zhu B (2010)	1
TKT	2	VCP	6	biochemical	Wan C (2015)	1
HSP90AA1	7	APP	1	affinity chromatography technology	Kumar P (2007)	1
STAT1	1	PRKCD	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, biochemical	Kristof AS (2003), Kristof AS (2003), DeVries TA (2004), DeVries TA (2004), Uddin S (2002), Uddin S (2002), Uddin S (2002), Deb DK (2003), Deb DK (2003), Fielhaber JA (2009), Fielhaber JA (2009)	11
TRIM41	6	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
TRO	1	PRKCD	2	affinity chromatography technology	Tamura N (2011)	1
MYC	2	AFAP1	3	affinity chromatography technology	Agrawal P (2010)	1
YWHAZ	1	PRKCD	2	affinity chromatography technology	Gannon-Murakami L (2002)	1
VHL	0	APP	1	pull down	Olah J (2011)	1
MYC	2	EP300	36	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, enzymatic study, affinity chromatography technology, affinity chromatography technology	Faiola F (2005), Faiola F (2005), Faiola F (2005), Faiola F (2005), Faiola F (2005), Zhang K (2005), Covic M (2005), Fujii M (2006)	8
HSP90AA1	7	GSK3A	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Taipale M (2012)	2
AFAP1	3	PRKCD	2	pull down	Qian Y (2002)	1
INSR	9	PRKCD	2	affinity chromatography technology, affinity chromatography technology	Braiman L (2001), Rosenzweig T (2002)	2
IRAK1	1	IKBKB	1	affinity chromatography technology, affinity chromatography technology	Vig E (2001), Windheim M (2008)	2
RANBP9	5	RANBP10	0	affinity chromatography technology	Boldt K (2016)	1
HDAC5	4	YWHAZ	1	affinity chromatography technology, affinity chromatography technology	Greco TM (2011), Joshi P (2013)	2
MALT1	1	IKBKB	1	affinity chromatography technology	Bidere N (2009)	1
STAT1	1	IRAK1	1	affinity chromatography technology, affinity chromatography technology	Nguyen H (2003), Nguyen H (2003)	2
HSP90AA1	7	STAT3	0	affinity chromatography technology	Sato N (2003)	1
VHL	0	PPP2CA	7	affinity chromatography technology, affinity chromatography technology	Guo J (2016), Guo J (2016)	2
SQSTM1	0	PRKCD	2	affinity chromatography technology	Linares JF (2011)	1
ELAVL1	0	YWHAG	5	affinity chromatography technology	Abdelmohsen K (2009)	1
VHL	0	PLD2	1	affinity chromatography technology, pull down, pull down	Park MH (2015), Park MH (2015), Park MH (2015)	3
HSP90AA1	7	MYC	2	affinity chromatography technology	Carystinos GD (2003)	1
CHUK	5	CARD11	4	affinity chromatography technology, imaging technique	McCully RR (2008), Sommer K (2005)	2
PRKCD	2	HIST1H1A	0	enzymatic study, enzymatic study	Lee SJ (2006), Fontayne A (2002)	2
HDAC5	4	VCP	6	affinity chromatography technology	Greco TM (2011)	1
EP300	36	HIST1H1A	0	enzymatic study, enzymatic study	Loven MA (2004), Sakaguchi K (1998)	2
PRKCD	2	HSPA4	3	pull down	Rex EB (2010)	1
GABRA1	6	PRKCD	2	affinity chromatography technology	Kumar S (2002)	1
CHUK	5	TRAF6	0	affinity chromatography technology	Kishida S (2005)	1
PRKCD	2	MBP	0	enzymatic study	Ren J (2002)	1
YWHAG	5	PRPF4B	3	affinity chromatography technology	Ewing RM (2007)	1
RIPK4	0	YWHAZ	1	affinity chromatography technology	Rodriguez J (2016)	1
RIPK4	0	IRAK1	1	affinity chromatography technology	Rodriguez J (2016)	1
C1QBP	0	PHB	0	affinity chromatography technology	Yagi M (2012)	1
PRKCD	2	RANBP10	0	affinity chromatography technology	Rex EB (2010)	1
VHL	0	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Chen K (2016), Chen K (2016)	2
RIPK4	0	SQSTM1	0	affinity chromatography technology	Rodriguez J (2016)	1
HDAC5	4	TKT	2	affinity chromatography technology	Greco TM (2011)	1
PRKCD	2	PRKCB	4	affinity chromatography technology	Varjosalo M (2013)	1
SHC1	0	APP	1	pull down, affinity chromatography technology	Tarr PE (2002), Tarr PE (2002)	2
VCP	6	MTOR	14	affinity chromatography technology	Yu CC (2013)	1
PRKCD	2	PRKCD	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study	Niture SK (2009), Uddin S (2002), Doller A (2008), Ren J (2002)	4
IRAK1	1	CHUK	5	affinity chromatography technology, affinity chromatography technology	Vig E (2001), Windheim M (2008)	2
NOTCH1	25	PPP2CA	7	affinity chromatography technology, affinity chromatography technology	Yatim A (2012), Yatim A (2012)	2
HDAC5	4	FXR1	0	affinity chromatography technology	Greco TM (2011)	1
GNA12	2	HSP90AA1	7	affinity chromatography technology, two hybrid	Vaiskunaite R (2001), Vaiskunaite R (2001)	2
SQSTM1	0	MTOR	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Duran A (2011), Linares JF (2015), Linares JF (2015)	3
TRAF6	0	SNCA	0	affinity chromatography technology	Zucchelli S (2010)	1
IKBKB	1	IRS1	7	affinity chromatography technology	Gao Z (2002)	1
HSP90AA1	7	HSPA4	3	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Kim TS (2006), Hidalgo-de-Quintana J (2008), Skarra DV (2011), Wan C (2015)	4
TP53	0	CHUK	5	affinity chromatography technology	Huang WC (2007)	1
TRAF6	0	IRAK1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Wesche H (1999), Qian Y (2001), Cao Z (1996), Takatsuna H (2003), Li S (2002), Ling L (2000), Ling L (2000), Takaesu G (2001), Muzio M (1997), Chen F (2008), Li X (2001), Li X (2001), Xiong Y (2011), Xiong Y (2011), Tang H (2010), Muroi M (2011), Liu A (2012), Lee JY (2009), Lee JY (2009), Kollewe C (2004), Jiang Z (2002), Jensen LE (2001), Liu G (2007), Liu G (2007), Jiang Z (2003), Nguyen T (2009), Choi KC (2006), Rao N (2005), Rao N (2005), Lakshmanan U (2007), Lee HJ (2012), Lee HJ (2012), Zhang X (2013), Yao J (2007), Hu MM (2014), Jeon J (2014), Conze DB (2008), Tanishima M (2017)	38
STAT3	0	FYN	1	pull down	Schreiner SJ (2002)	1
PRKCD	2	TRAPPC13	0	affinity chromatography technology	Hein MY (2015)	1
EP300	36	YWHAZ	1	enzymatic study	Mortenson JB (2015)	1
PRKCD	2	DIABLO	2	affinity chromatography technology, affinity chromatography technology	Masoumi KC (2012), Masoumi KC (2012)	2
HSPB1	2	HSPA4	3	two hybrid	Katsogiannou M (2014)	1
PRKCB	4	IKBKB	1	imaging technique	Chen TC (2014)	1
HSPB1	2	IKBKB	1	affinity chromatography technology	Kammanadiminti SJ (2006)	1
PPP2CA	7	PRKCD	2	enzymatic study	Srivastava J (2002)	1
FYN	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Loewenberg M (2006), Taipale M (2012), Taipale M (2012), Huttlin EL (2017)	4
INSR	9	SHC1	0	two hybrid, pull down	Kasus-Jacobi A (2000), Wolf G (1995)	2
PRKCD	2	HDAC5	4	enzymatic study	Huynh QK (2011)	1
PRKCB	4	HIST1H1B	4	enzymatic study	Thompson LJ (1996)	1
CHUK	5	MTOR	14	affinity chromatography technology, affinity chromatography technology, biochemical	Dan HC (2008), Dan HC (2008), Dan HC (2008)	3
MYC	2	C1QBP	0	affinity chromatography technology	Koch HB (2007)	1
TP73	2	MYC	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Uramoto H (2002), Uramoto H (2002), Uramoto H (2002), Watanabe K (2002), Watanabe K (2002)	5
VCP	6	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Yu CC (2013), Fogeron ML (2013)	3
HSPA4	3	VCP	6	affinity chromatography technology, affinity chromatography technology	Vij N (2006), Yu CC (2013)	2
PRKCB	4	IBTK	3	enzymatic study, affinity chromatography technology	Janda E (2011), Janda E (2011)	2
KLF4	2	VHL	0	affinity chromatography technology, pull down	Gamper AM (2012), Gamper AM (2012)	2
HSPB1	2	CHUK	5	affinity chromatography technology	Kammanadiminti SJ (2006)	1
PPP2CA	7	CHUK	5	affinity chromatography technology	Kray AE (2005)	1
SQSTM1	0	MBP	0	pull down	Pridgeon JW (2004)	1
GNA12	2	APP	1	pull down	Olah J (2011)	1
HSP90AA1	7	SNCA	0	pull down	Falsone SF (2009)	1
PRKCD	2	PDP2	1	affinity chromatography technology	Caruso M (2001)	1
MTOR	14	YWHAZ	1	affinity chromatography technology, genetic interference	Vander Haar E (2007), Srivas R (2016)	2
PRKCD	2	54145	0	affinity chromatography technology	Hein MY (2015)	1
HSPA4	3	MTOR	14	affinity chromatography technology, affinity chromatography technology	Martin J (2008), Martin J (2008)	2
IRAK1	1	PRKCD	2	affinity chromatography technology	Tiwari RL (2011)	1
PRKCD	2	MTOR	14	affinity chromatography technology, affinity chromatography technology	Kumar V (2000), Kumar V (2000)	2
PRKCB	4	EP300	36	enzymatic study	Yuan LW (2000)	1
IRS1	7	PIK3CB	2	affinity chromatography technology	Kuchay S (2013)	1
HDAC5	4	PPP2CA	7	affinity chromatography technology, affinity chromatography technology	Martin M (2008), Greco TM (2011)	2
PRKCD	2	GNA13	0	enzymatic study	Offermanns S (1996)	1
TP73	2	PRKCD	2	affinity chromatography technology, pull down, enzymatic study	Ren J (2002), Ren J (2002), Ren J (2002)	3
HDAC5	4	PHB	0	affinity chromatography technology, affinity chromatography technology	Greco TM (2011), Joshi P (2013)	2
PRKCD	2	CHD9	5	affinity chromatography technology	Hein MY (2015)	1
PRKCQ	3	IKBKB	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Khoshnan A (2000), Lee KY (2005), Lee KY (2005), Srivastava R (2010), Shambharkar PB (2007)	5
TRAF6	0	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sanz L (2000), Sanz L (2000), Nakamura K (2010), Kim JY (2009), Seibenhener ML (2004), Feng Y (2005), Martin P (2006), Martin P (2006), Geetha T (2012), Geetha T (2012), Linares JF (2013), Linares JF (2011), Linares JF (2015), Schimmack G (2017), Tsai WT (2016)	15
VCP	6	APP	1	affinity chromatography technology	Jang JK (2017)	1
PRKCD	2	MACF1	12	pull down	Rex EB (2010)	1
SNCA	0	FXR1	0	affinity chromatography technology	Hein MY (2015)	1
MYC	2	TIAM1	3	affinity chromatography technology, pull down	Otsuki Y (2003), Otsuki Y (2003)	2
EP300	36	PPP2CA	7	affinity chromatography technology	Chen J (2005)	1
PRKCD	2	GNA12	2	enzymatic study	Offermanns S (1996)	1
PPP2CA	7	TP53	0	affinity chromatography technology	Shouse GP (2011)	1
EP300	36	KLF4	2	pull down, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Evans PM (2007), Yu K (2011), Yu K (2011), Zhang R (2010), Allen KL (2011)	5
IRAK1	1	HSPB1	2	affinity chromatography technology	So J (2015)	1
HSP90AA1	7	PRKCQ	3	affinity chromatography technology	Taipale M (2012)	1
YWHAZ	1	YWHAG	5	biochemical, biochemical, affinity chromatography technology, fluorescent resonance energy transfe	Kristensen AR (2012), Wan C (2015), Hein MY (2015), Ivanov AA (2017)	4
PRKCD	2	PTGES3	0	biochemical	Wan C (2015)	1
APP	1	MYC	2	pull down	Virok DP (2011)	1
PDPK1	0	PRKCQ	3	affinity chromatography technology, affinity chromatography technology	Lee KY (2005), Lee KY (2005)	2
ELAVL1	0	CHUK	5	affinity chromatography technology	Chu PC (2012)	1
PRKCD	2	RANBP9	5	affinity chromatography technology	Rex EB (2010)	1
TP53	0	HSPA4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Muller P (2008), Fraser JA (2010), Sun Y (2007), Wang J (2011), Horikawa I (2014), Horikawa I (2014), Kishor A (2013)	7
TP53	0	EP300	36	pull down, genetic interference, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, x-ray crystallography, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, unspecified method, affinity chromatography technology, enzymatic study, unspecified method, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, unspecified method	An W (2004), Pastorcic M (2000), Livengood JA (2002), Livengood JA (2002), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Tang Y (2008), Wang H (2008), Valbuena A (2008), Shi D (2009), Vega FM (2004), Finlan L (2004), Groenroos E (2004), Zhao Y (2006), Roe JS (2006), Pedeux R (2005), Sekaric P (2007), Pan X (2009), Tang Y (2006), Sen GS (2011), Li Y (2012), Li Y (2012), Gillotin S (2010), Grossman SR (2003), Issaeva N (2004), Kitagawa M (2008), Sabbatini P (2002), Burge S (2009), Zilfou JT (2001), Issaeva N (2004), Issaeva N (2004), Feng H (2009), Feng H (2009), Lill NL (1997), Dornan D (2004), Dornan D (2004), Di Agostino S (2006), Wells M (2008), Fath DM (2006), Kobet E (2000), Costanzo A (2002), Kumazawa T (2011), Borger DR (2006), Cui D (2013), Borger DR (2006), Lee SJ (2013), Tang HY (2006), Lin C (2011), Choi WI (2014), Ding G (2013), Kim MK (2013), Ali A (2013), Wu G (2014), Mizuguchi Y (2012), Sinha S (2012), Sinha S (2012), Her YR (2013), Her YR (2013), Wu SY (2009), Wu SY (2009), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Gu W (1997), Teufel DP (2007), Mantovani F (2007), Mantovani F (2007), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), MacPartlin M (2005), Mujtaba S (2004), Wang YH (2003), Chen H (1999), Tang Z (2013), Graczyk A (2013), Graczyk A (2013), Chan HM (2001), Thomas MC (2005), Miller Jenkins LM (2015), Miller Jenkins LM (2015), Koh DI (2014), Koh DI (2014), Koh DI (2014), Li H (2015), Chen LF (2005), Shi D (2016), Wright DG (2016), Zhang X (2016), Procopio MG (2015), Tong Q (2015)	95
VHL	0	HSP90AA1	7	affinity chromatography technology, genetic interference	Yang C (2013), Shen JP (2017)	2
PRKCD	2	ITPR1	25	pull down	Rex EB (2010)	1
PRKCD	2	PDP1	1	affinity chromatography technology	Caruso M (2001)	1
SHC1	0	PRKCD	2	affinity chromatography technology, pull down, affinity chromatography technology	Leitges M (2002), Leitges M (2002), Brehme M (2009)	3
STAT3	0	TRAF6	0	affinity chromatography technology, affinity chromatography technology	Wei J (2012), Wei J (2012)	2
VCP	6	STAT1	1	affinity chromatography technology	Yu CC (2013)	1
VHL	0	SPRY2	4	affinity chromatography technology	Anderson K (2011)	1
PRKCD	2	NCF1	2	enzymatic study	Fontayne A (2002)	1
ELAVL1	0	SPRY2	4	affinity chromatography technology	Abdelmohsen K (2009)	1
PTPN6	0	PTK2B	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ganju RK (2000), Ganju RK (2000), Kumar S (1999), Kumar S (1999), Kumar S (1999)	5
RIPK4	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
RPL37A	0	BUD13	0	affinity chromatography technology	Huttlin EL (2017)	1
PRKCD	2	KLF4	2	affinity chromatography technology, affinity chromatography technology	Zhang XH (2012), Zhang XH (2012)	2
APP	1	SNCA	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, imaging technique	Jensen PH (1997), Yoshimoto M (1995), Tsigelny IF (2008), Tsigelny IF (2008), Tsigelny IF (2008), Olah J (2011), Chen TC (2014)	7
HDAC5	4	TP53	0	affinity chromatography technology	Greco TM (2011)	1
DAB2	1	MALT1	1	affinity chromatography technology	Mulkearns EE (2012)	1
TRIM41	6	PRKCD	2	affinity chromatography technology	Chen D (2007)	1
PRKCD	2	IBTK	3	affinity chromatography technology	Janda E (2011)	1
SQSTM1	0	SNCA	0	imaging technique	Schwarz L (2012)	1
PRKCD	2	PTK2B	6	affinity chromatography technology	Wrenn RW (2001)	1
PRKCB	4	GNA12	2	enzymatic study	Offermanns S (1996)	1
SP1	0	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin S (2006), Zhang Y (2007), Zhang Y (2007), Proietti CJ (2011)	4
VHL	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Roe JS (2006), Roe JS (2006), Roe JS (2006), Lai Y (2011), Lai Y (2011)	5
PRKCB	4	RASGRP3	3	enzymatic study, enzymatic study	Brodie C (2004), Teixeira C (2003)	2
HSPB1	2	HSP90AA1	7	two hybrid	Katsogiannou M (2014)	1
PTPN6	0	INSR	9	affinity chromatography technology	Uchida T (1994)	1
PRKCB	4	GSK3A	1	enzymatic study	Fang X (2002)	1
ELAVL1	0	VCP	6	affinity chromatography technology, pull down	Zhou HL (2013), Zhou HL (2013)	2
HSP90AA1	7	PTGES3	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down	McLaughlin SH (2002), Mollapour M (2010), Kovacs JJ (2005), Giommarelli C (2010), Tsutsumi S (2012), Lee YT (2004), Schuelke JP (2010), Sarkar S (2012), Gano JJ (2010), Zelin E (2012), Obermann WM (1998), Wang J (2011), Weaver AJ (2000), Donze O (2001), Shimamura T (2012), Chan CT (2008), Chan CT (2008), Graumann K (2000), Martinez-Yamout MA (2006), Chadli A (2010), Woo SH (2009), Woo SH (2009), Woo SH (2009), Ni L (2010), Chadli A (2008), Picard D (2006), Wochnik GM (2004), Woodford MR (2016), Scholz GM (2001), McLaughlin SH (2006), Sun L (2012), Woodford MR (2016), Lepvrier E (2015)	33
PRKCD	2	HSPB1	2	affinity chromatography technology	Lee YJ (2005)	1
HSP90AA1	7	CHUK	5	affinity chromatography technology, affinity chromatography technology	Qu X (2012), Gano JJ (2010)	2
MYC	2	GSK3A	1	affinity chromatography technology, affinity chromatography technology, pull down	Gregory MA (2003), Gregory MA (2003), Gregory MA (2003)	3
PLD2	1	PRKCD	2	affinity chromatography technology, pull down	Han JM (2002), Han JM (2002)	2
HDAC5	4	HSP90AA1	7	affinity chromatography technology	Greco TM (2011)	1
TNFRSF1A	3	STAT1	1	affinity chromatography technology	Wang Y (2000)	1
RASGRP3	3	APP	1	pull down	Olah J (2011)	1
PRKCD	2	ACTBL2	0	affinity chromatography technology	Hein MY (2015)	1
PTGES3	0	TKT	2	biochemical	Wan C (2015)	1
PRKCD	2	FLI1	2	enzymatic study, affinity chromatography technology	Asano Y (2009), Asano Y (2009)	2
SQSTM1	0	YWHAZ	1	pull down	Pridgeon JW (2004)	1
TP53	0	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Borellini F (1993), Jin W (2008), Dhar SK (2006), Lagger G (2003), Lagger G (2003), Lagger G (2003), Lagger G (2003), Sengupta S (2005), Sengupta S (2005), Lin RK (2010), Kim HA (2011), Sawaya BE (1998), St Clair S (2004), Innocente SA (2005), Innocente SA (2005), Ohlsson C (1998), Kong X (2013), Bocangel D (2009), Bocangel D (2009)	19
VHL	0	ACTBL2	0	affinity chromatography technology	Huttlin EL (2017)	1
MALT1	1	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Martin P (2006), Martin P (2006)	2
TRAF6	0	APP	1	pull down	Olah J (2011)	1
VHL	0	SP1	0	affinity chromatography technology, affinity chromatography technology, pull down	Yuen JS (2007), Mukhopadhyay D (1997), Mukhopadhyay D (1997)	3
PRKCQ	3	YWHAG	5	affinity chromatography technology	Autieri MV (1999)	1
PRKCB	4	CARD11	4	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Sommer K (2005), Sommer K (2005), Sommer K (2005), Sommer K (2005)	4
PHB	0	YWHAZ	1	affinity chromatography technology, affinity chromatography technology	Zhu B (2010), Zhu B (2010)	2
PRKCD	2	DAB2	1	enzymatic study	Tseng CP (1999)	1
IRAK1	1	STAT3	0	affinity chromatography technology, affinity chromatography technology	Huang Y (2004), Huang Y (2004)	2
NOTCH1	25	PRKCD	2	affinity chromatography technology, enzymatic study	Sjoeqvist M (2014), Sjoeqvist M (2014)	2
PRKCD	2	VCP	6	pull down	Rex EB (2010)	1
INSR	9	IRS1	7	two hybrid, two hybrid, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Aguirre V (2002), Sawka-Verhelle D (1996), Strack V (2002), Wolf G (1995), Kwon H (2015), Kwon H (2015)	6
SPRY2	4	PPP2CA	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chandramouli S (2008), Lao DH (2007), Lao DH (2007)	3
HSP90AA1	7	DYNC1H1	41	affinity chromatography technology	Gano JJ (2010)	1
PDPK1	0	APP	1	pull down	Olah J (2011)	1
PRKCD	2	PRKCQ	3	affinity chromatography technology	Varjosalo M (2013)	1
SQSTM1	0	NOTCH1	25	affinity chromatography technology, affinity chromatography technology	Ahn JS (2016), Ahn JS (2016)	2
KLF4	2	APP	1	pull down	Olah J (2011)	1
GABRA1	6	VCP	6	affinity chromatography technology	Di XJ (2016)	1
CARD11	4	MALT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang S (2013), Karim ZA (2015), Liu Y (2012)	3
PRKCD	2	NFE2L2	1	enzymatic study, affinity chromatography technology	Niture SK (2009), Niture SK (2009)	2
KLF4	2	HDAC5	4	affinity chromatography technology, affinity chromatography technology	Yoshida T (2008), Yoshida T (2008)	2
FYN	1	SNCA	0	enzymatic study, enzymatic study, enzymatic study	Nakamura T (2001), Payton JE (2004), Ellis CE (2001)	3
RPL37A	0	APP	1	pull down	Olah J (2011)	1
PRKCB	4	YWHAG	5	affinity chromatography technology	Autieri MV (1999)	1
MALT1	1	DIABLO	2	affinity chromatography technology	Garrison JB (2009)	1
CHUK	5	PRKCD	2	pull down, affinity chromatography technology, affinity chromatography technology	Lallena MJ (1999), Lallena MJ (1999), Lallena MJ (1999)	3
PRKCB	4	CHUK	5	imaging technique	Chen TC (2014)	1
PRKCD	2	SNCA	0	affinity chromatography technology, affinity chromatography technology	Kaul S (2005), Kaul S (2005)	2
HSPA4	3	APP	1	affinity chromatography technology	Kumar P (2007)	1
PRKCD	2	HSP90AA1	7	pull down	Rex EB (2010)	1
PRKCD	2	GRM5	6	imaging technique	Chen TC (2014)	1
HSPB1	2	YWHAZ	1	two hybrid	Katsogiannou M (2014)	1
TNFRSF1A	3	PRKCD	2	affinity chromatography technology, enzymatic study	Kilpatrick LE (2000), Kilpatrick LE (2000)	2
IL6ST	0	PRKCD	2	affinity chromatography technology	Novotny-Diermayr V (2002)	1
CHUK	5	TNFRSF1A	3	enzymatic study, affinity chromatography technology, affinity chromatography technology	Guan YJ (2011), Guan YJ (2011), Mitsuhashi S (2008)	3
PRKCQ	3	NFE2L2	1	enzymatic study	Niture SK (2009)	1
MYC	2	CHD9	5	affinity chromatography technology	Hein MY (2015)	1
PRKCD	2	APP	1	pull down	Olah J (2011)	1
TP53	0	SQSTM1	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Di Lello P (2006), Horikawa I (2014), Kang JH (2016), Kang JH (2016)	4
PIK3CB	2	PRKCD	2	affinity chromatography technology	Stetak A (2001)	1
STAT3	0	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology	Gunaje JJ (2001), Spiekermann K (2001), Xia L (2002), Chen TC (2014), Li X (2015), Ghosh MK (2005), Huttlin EL (2017)	7
SP1	0	KLF4	2	pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique	Zhang W (1998), Zhang XH (2012), Zhang XH (2012), Zhang XH (2012), Zhang XH (2012)	5
TP73	2	IKBKB	1	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, enzymatic study	Accardi R (2011), Accardi R (2011), Accardi R (2011), Accardi R (2011)	4
YWHAZ	1	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology	Waterman MJ (1998), Waterman MJ (1998), Gu YM (2006)	3
PRKCQ	3	RASGRP3	3	enzymatic study	Teixeira C (2003)	1
HSPB1	2	SQSTM1	0	two hybrid	Katsogiannou M (2014)	1
TP53	0	RPL37A	0	affinity chromatography technology	Fogeron ML (2013)	1
SQSTM1	0	HSPA4	3	pull down, affinity chromatography technology	Pridgeon JW (2004), Pridgeon JW (2004)	2
TNFRSF1A	3	FYN	1	biochemical	Legler DF (2003)	1
YWHAG	5	TIAM1	3	affinity chromatography technology	Jin J (2004)	1
SQSTM1	0	TKT	2	pull down	Pridgeon JW (2004)	1
PRKCB	4	DAB2	1	enzymatic study	Tseng CP (1999)	1
TRAF6	0	MTOR	14	affinity chromatography technology, enzymatic study	Linares JF (2013), Linares JF (2013)	2
PTPN6	0	RPL37A	0	affinity chromatography technology	Li X (2016)	1
ITGB2	4	RANBP9	5	two hybrid, pull down, affinity chromatography technology	Denti S (2004), Denti S (2004), Denti S (2004)	3
PRKCD	2	HIST1H1B	4	enzymatic study, enzymatic study	Kaul S (2005), Uddin S (2002)	2
NCF1	2	PRKCB	4	affinity chromatography technology, enzymatic study	Korchak HM (2001), Fontayne A (2002)	2
DAB2	1	INPP5D	2	pull down	Morris SM (2001)	1
PRKCD	2	ZNF131	0	affinity chromatography technology	Hein MY (2015)	1
IRAK1	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, biochemical	De Nardo D (2005), De Nardo D (2005), De Nardo D (2005)	3
EP300	36	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Paulson M (1999), Hiroi M (2003), Ray S (2002), Strassheim D (2009), Liu X (2008), Ghosh AK (2001), Yang WS (2005), Zhang Y (2015), Kotla S (2015), Kotla S (2015)	10
IRS1	7	MTOR	14	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ozes ON (2001), Tzatsos A (2006), Tzatsos A (2006)	3
PRKCD	2	TKT	2	affinity chromatography technology	Hein MY (2015)	1
INPP5D	2	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dunant NM (2000), Dunant NM (2000), Wisniewski D (1999), Leitges M (2002), Damen JE (1996), Damen JE (1996), March ME (2000), Hunter MG (2004), Ho JM (2002)	9
ELAVL1	0	GNA13	0	affinity chromatography technology	Abdelmohsen K (2009)	1
APP	1	YWHAG	5	two hybrid, affinity chromatography technology, unspecified method	Sumioka A (2005), Sumioka A (2005), Sumioka A (2005)	3
MYC	2	PRKCD	2	genetic interference	Zhou Z (2014)	1
HSPA4	3	PRKCB	4	affinity chromatography technology, pull down	Gao T (2006), Gao T (2006)	2
MYC	2	TKT	2	affinity chromatography technology	Agrawal P (2010)	1
MTOR	14	PLD2	1	affinity chromatography technology	Ha SH (2006)	1
ELAVL1	0	MYC	2	affinity chromatography technology	Abdelmohsen K (2009)	1
PRKCB	4	TIAM1	3	enzymatic study	Fleming IN (1999)	1
SNCA	0	DYNC1H1	41	unspecified method, affinity chromatography technology	Woods WS (2007), Hein MY (2015)	2
HDAC5	4	HSPA4	3	affinity chromatography technology	Greco TM (2011)	1
TRAF6	0	VCP	6	affinity chromatography technology	Ewing RM (2007)	1
TP73	2	EP300	36	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Strano S (2005), Uramoto H (2004), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Mantovani F (2004), Burge S (2009), Burge S (2009), Costanzo A (2002), Hoffmann A (2008), Kramer D (2015)	13
PTK2B	6	ITGB2	4	affinity chromatography technology	Miura Y (2000)	1
IKBKB	1	MTOR	14	affinity chromatography technology, affinity chromatography technology, biochemical	Dan HC (2008), Dan HC (2008), Dan HC (2008)	3
ELAVL1	0	TNFRSF1A	3	affinity chromatography technology	Abdelmohsen K (2009)	1
MYC	2	DYNC1H1	41	affinity chromatography technology	Koch HB (2007)	1
SP1	0	ACTBL2	0	affinity chromatography technology	Chuang JY (2012)	1
RIPK4	0	PTGES3	0	affinity chromatography technology	Rodriguez J (2016)	1
IKBKB	1	HSP90AA1	7	affinity chromatography technology	Xue J (2010)	1
IKBKB	1	TP53	0	enzymatic study	Xia Y (2009)	1
IKBKB	1	MUC1	0	affinity chromatography technology, biochemical	Ahmad R (2007), Ahmad R (2007)	2
MUC1	0	ACTBL2	0	affinity chromatography technology	Huttlin EL (2017)	1
MYC	2	TP53	0	affinity chromatography technology, fluorescent resonance energy transfe	Agrawal P (2010), Ivanov AA (2017)	2
TNFRSF1A	3	TRAF6	0	affinity chromatography technology	Chang YL (2014)	1
PRKCB	4	ITGB2	4	enzymatic study	Fagerholm S (2002)	1
PRKCD	2	ELAVL1	0	enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Doller A (2007), Doller A (2008), Doller A (2008), Doller A (2011), Doller A (2011), Doller A (2010)	6
PRKCQ	3	CHUK	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee KY (2005), Srivastava R (2010), Shambharkar PB (2007)	3
MYC	2	HSPB1	2	affinity chromatography technology, affinity chromatography technology	Koch HB (2007), Agrawal P (2010)	2
EP300	36	CHUK	5	imaging technique	Hao L (2010)	1
HSP90AA1	7	PRKCB	4	affinity chromatography technology	Taipale M (2012)	1
TRAF6	0	FYN	1	pull down	Liu A (2012)	1
CWC15	0	APP	1	pull down	Olah J (2011)	1
STAT1	1	MTOR	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique	Kristof AS (2003), Kristof AS (2003), Fielhaber JA (2009), Fielhaber JA (2009), Fielhaber JA (2009), Chen TC (2014)	6
MUC1	0	PRKCD	2	affinity chromatography technology, pull down, enzymatic study	Ren J (2002), Ren J (2002), Ren J (2002)	3
PRKCD	2	IRS1	7	affinity chromatography technology, enzymatic study	Rosenzweig T (2002), del Rincon SV (2004)	2
MYC	2	NFE2L2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Levy S (2010), Levy S (2010), Ramani K (2012)	3
PRKCD	2	EP300	36	enzymatic study	Yuan LW (2000)	1
PRKCD	2	STAT3	0	affinity chromatography technology, enzymatic study	Jain N (1999), Jain N (1999)	2
PRKCD	2	RASGRP3	3	enzymatic study, affinity chromatography technology, affinity chromatography technology	Brodie C (2004), Brodie C (2004), Brodie C (2004)	3
PRKCQ	3	CARD11	4	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Srivastava R (2010), Sommer K (2005), Eitelhuber AC (2011), Liu Y (2012), Brenner D (2009)	5
MYC	2	PPP2CA	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Arnold HK (2009), Junttila MR (2007), Cianfanelli V (2015), Cianfanelli V (2015)	4
VCP	6	PTGES3	0	biochemical	Wan C (2015)	1
EP300	36	NOTCH1	25	affinity chromatography technology, enzymatic study, affinity chromatography technology, two hybrid	Hao L (2010), Popko-Scibor AE (2011), Popko-Scibor AE (2011), Popko-Scibor AE (2011)	4
C1QBP	0	PRKCD	2	pull down, affinity chromatography technology	Storz P (2000), Storz P (2000)	2
PHB	0	TP53	0	imaging technique, affinity chromatography technology, pull down	Fusaro G (2003), Fusaro G (2003), Fusaro G (2003)	3
PRKCD	2	FYN	1	imaging technique	Chen TC (2014)	1
SP1	0	HSP90AA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Hung JJ (2005), Hung JJ (2005), Wang SA (2009), Wang SA (2009)	4
PRKCD	2	PRPF4B	3	affinity chromatography technology	Hein MY (2015)	1
PRKCD	2	RIPK4	0	affinity chromatography technology, affinity chromatography technology	Bhr C (2000), Rodriguez J (2016)	2
PDPK1	0	PRKCB	4	pull down	Gao T (2001)	1
HSPB1	2	TKT	2	biochemical	Wan C (2015)	1
PRKCD	2	GSK3A	1	enzymatic study	Fang X (2002)	1
IRAK1	1	PPP2CA	7	affinity chromatography technology, affinity chromatography technology	Dobierzewska A (2011), Dobierzewska A (2011)	2
PRKCD	2	TP53	0	affinity chromatography technology	Lee SJ (2006)	1
GNA13	0	PTK2B	6	affinity chromatography technology	Shi CS (2000)	1
MALT1	1	PRKCD	2	affinity chromatography technology	Liu Y (2012)	1
INPP5D	2	PRKCD	2	affinity chromatography technology	Leitges M (2002)	1
MTOR	14	STAT3	0	pull down, affinity chromatography technology, affinity chromatography technology	Yokogami K (2000), Kusaba H (2005), Yang F (2013)	3
PRKCD	2	PPRC1	10	affinity chromatography technology	Hein MY (2015)	1
MALT1	1	TRAF6	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sun L (2004), Sun L (2004), Garrison JB (2009), Li Y (2013), Oeckinghaus A (2007), Oeckinghaus A (2007), Nie Z (2015), Liu Y (2012), Liu Y (2012)	9
NOTCH1	25	RANBP10	0	affinity chromatography technology	Yatim A (2012)	1
TRAF6	0	RANBP9	5	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology	Wang L (2011), Wang L (2011), Wang L (2011), Wang L (2011), Wang L (2011), Zhang J (2014)	6
ELAVL1	0	FXR1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
PRKCB	4	HIST1H1A	0	enzymatic study	Fontayne A (2002)	1
CARD11	4	PRKCD	2	affinity chromatography technology	Liu Y (2012)	1
MYC	2	VHL	0	affinity chromatography technology, affinity chromatography technology	Hwang IY (2012), Hwang IY (2012)	2
NOTCH1	25	APP	1	genetic interference, affinity chromatography technology	Kim SY (2007), Kim SY (2007)	2
EP300	36	VHL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Roe JS (2006), Roe JS (2011), Roe JS (2011), Ji W (2014), Chen K (2015)	5
MTOR	14	EP300	36	enzymatic study	Wan W (2017)	1
PRKCD	2	YWHAG	5	affinity chromatography technology	Autieri MV (1999)	1
PPP2CA	7	IKBKB	1	affinity chromatography technology	Kray AE (2005)	1
ADAM9	0	PRKCD	2	affinity chromatography technology	Izumi Y (1998)	1
VCP	6	HSPB1	2	affinity chromatography technology	Yu CC (2013)	1
SQSTM1	0	NFE2L2	1	imaging technique	Lau A (2010)	1
TRAF6	0	CARD11	4	affinity chromatography technology	McCully RR (2008)	1
IKBKB	1	CHUK	5	affinity chromatography technology, biochemical, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Zandi E (1997), Chen G (2002), Otsuki T (2002), May MJ (2000), May MJ (2000), Woronicz JD (1997), Woronicz JD (1997), Deng L (2000), Yeung KC (2001), Mercurio F (1997), Mercurio F (1997), Rothwarf DM (1998), Wu ZH (2010), Li S (2011), Li S (2011), May MJ (2002), Heilker R (1999), Leotoing L (2011), McKenzie FR (2000), Zandi E (1998), Lee DF (2007), Li XH (2001), Yeh PY (2011), Yeh PY (2011), Stehlik C (2002), Li Q (2006), So J (2015), Chen TC (2014), Karim ZA (2015), Huttlin EL (2017)	30
CHUK	5	TP73	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Furuya K (2007), Furuya K (2007), Accardi R (2011), Accardi R (2011)	4
VCP	6	PPP2CA	7	affinity chromatography technology, affinity chromatography technology	Ohama T (2010), Yakovlev VA (2013)	2
RIPK4	0	HSPB1	2	affinity chromatography technology	Rodriguez J (2016)	1
IRAK1	1	HSPA4	3	affinity chromatography technology, affinity chromatography technology	De Nardo D (2005), De Nardo D (2005)	2
STAT3	0	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nakashima K (1999), Nakashima K (1999), Ray S (2002), Ray S (2002), Yuan ZL (2005), Yuan ZL (2005), Gupta M (2011), Wang R (2005), Gray MJ (2005), Hou T (2008), Kotla S (2015)	11
PRKCB	4	GNA13	0	enzymatic study	Offermanns S (1996)	1
VHL	0	HSPA4	3	affinity chromatography technology	Yang C (2013)	1
FXR1	0	RANBP9	5	affinity chromatography technology	Li S (2014)	1
SQSTM1	0	IRAK1	1	affinity chromatography technology	Sanz L (2000)	1
VCP	6	YWHAZ	1	affinity chromatography technology, two hybrid	Yu CC (2013), Wang J (2011)	2
DHX16	5	APP	1	pull down	Olah J (2011)	1
TRAF6	0	IKBKB	1	affinity chromatography technology	Bidere N (2006)	1
ITPR1	25	VCP	6	affinity chromatography technology	Pearce MM (2009)	1
INSR	9	SQSTM1	0	enzymatic study, affinity chromatography technology	Sung CK (1998), Milan E (2015)	2
PRKCD	2	ART3	1	pull down	Rex EB (2010)	1
PRKCD	2	FXR1	0	affinity chromatography technology	Hein MY (2015)	1
DAB2	1	APP	1	pull down	Morris SM (2001)	1
SP1	0	MYC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Gartel AL (2001), Liu T (2007), Gordan JD (2007), Gordan JD (2007), Koshiji M (2005), Koshiji M (2005)	6
HDAC5	4	C1QBP	0	affinity chromatography technology	Greco TM (2011)	1
PRKCD	2	RPL37A	0	affinity chromatography technology	Hein MY (2015)	1
SNCA	0	HSPB1	2	affinity chromatography technology, pull down	Nemes Z (2009), Bruinsma IB (2011)	2
ELAVL1	0	STAT3	0	affinity chromatography technology	Abdelmohsen K (2009)	1
HSPB1	2	TP53	0	two hybrid, affinity chromatography technology, imaging technique	Stelzl U (2005), Sun Y (2007), Chen TC (2014)	3
PRKCQ	3	FYN	1	pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Ron D (1999), Ron D (1999), Ron D (1999), Ron D (1999), Ron D (1999), Ron D (1999), Ron D (1999)	7
PRKCD	2	ITGB2	4	enzymatic study	Fagerholm S (2002)	1
HSP90AA1	7	PRPF4B	3	affinity chromatography technology	Hein MY (2015)	1
RANBP9	5	APP	1	affinity chromatography technology	Lakshmana MK (2009)	1
SPRY2	4	PRKCD	2	affinity chromatography technology, affinity chromatography technology, far western blotting	Chow SY (2009), Chow SY (2009), Chow SY (2009)	3
RIPK4	0	HSPA4	3	affinity chromatography technology	Rodriguez J (2016)	1
TNFRSF1A	3	PRKCB	4	affinity chromatography technology	Kilpatrick LE (2000)	1
PRKCD	2	FAM192A	1	affinity chromatography technology	Hein MY (2015)	1
PRKCD	2	LYSMD2	2	affinity chromatography technology	Hein MY (2015)	1
CHUK	5	IRS1	7	affinity chromatography technology	Gao Z (2002)	1
CHUK	5	MYC	2	affinity chromatography technology, affinity chromatography technology	Yeh PY (2011), Yeh PY (2011)	2
PRKCB	4	MBP	0	enzymatic study	Sato T (2014)	1
PRKCD	2	BUD13	0	affinity chromatography technology	Hein MY (2015)	1
NCF1	2	NFE2L2	1	affinity chromatography technology	Ha Kim K (2017)	1
ELAVL1	0	FAM192A	1	affinity chromatography technology	Abdelmohsen K (2009)	1
MTOR	14	TP53	0	affinity chromatography technology, genetic interference	Su WC (2009), Ye H (2016)	2
PRKCD	2	CWC15	0	affinity chromatography technology	Hein MY (2015)	1
NOTCH1	25	RANBP9	5	affinity chromatography technology	Yatim A (2012)	1