PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
UBE2D3	1	RNF125	0	affinity chromatography technology, two hybrid	Arimoto K (2008), Markson G (2009)	2
CHFR	5	MAD2L1	0	affinity chromatography technology	Privette LM (2008)	1
MCM2	3	RANBP2	9	affinity chromatography technology	Drissi R (2015)	1
RELA	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Zhong H (2002), Zhong H (2002), Zhong H (2002), Zhong H (2002), Ashburner BP (2001), Ashburner BP (2001), OShea JM (2010), OShea JM (2010), Liu Y (2006), Cao W (2006), Hu J (2004), Hu J (2004), Sun JM (2007), Deckmann K (2012)	15
SMARCB1	1	CHFR	5	affinity chromatography technology, affinity chromatography technology, enzymatic study	Jung I (2012), Jung I (2012), Jung I (2012)	3
CHFR	5	CHFR	5	x-ray crystallography, enzymatic study, enzymatic study, enzymatic study	Stavridi ES (2002), Ahel I (2008), Chaturvedi P (2002), Kang D (2002)	4
CHFR	5	HDAC2	1	affinity chromatography technology, pull down	Oh YM (2009), Oh YM (2009)	2
CHFR	5	CDK5	0	affinity chromatography technology	Oh YM (2009)	1
CDC20	1	HDAC2	1	biochemical, affinity chromatography technology	Yoon YM (2004), Yoon YM (2004)	2
PBK	0	CHFR	5	affinity chromatography technology, affinity chromatography technology	Shinde SR (2013), Shinde SR (2013)	2
PCNA	0	CDK5	0	affinity chromatography technology, affinity chromatography technology	Takasaki Y (2001), Wu SM (1998)	2
SMARCA4	19	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Sif S (2001), Qiu Z (2008), Xu Z (2006), Pal S (2003), Battaglioli E (2002), Tando T (2010), Hang CT (2010), Shen JP (2017)	8
RELA	1	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UBE2D1	0	CHFR	5	two hybrid, pull down, pull down, pull down	Markson G (2009), Kim JM (2010), Kang D (2002), Jung I (2012)	4
UBE2D3	1	RELA	1	enzymatic study	Ryo A (2003)	1
UBE2D1	0	RNF7	0	two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Markson G (2009), Yasukawa T (2008), Zakaria R (2013), Kuang Z (2010), Lamsoul I (2011), Heuze ML (2008), Kershaw NJ (2014), Uematsu K (2016), Lo JY (2017)	9
UBE2E1	1	RELA	1	enzymatic study	Ryo A (2003)	1
TRIM25	5	EEF1G	0	affinity chromatography technology	Choudhury NR (2017)	1
UBE2D2	0	RNF125	0	two hybrid	Markson G (2009)	1
HDAC1	4	SMARCD1	5	biochemical	Havugimana PC (2012)	1
PARP1	3	UBE2I	0	two hybrid, affinity chromatography technology, pull down, enzymatic study, enzymatic study, pull down, enzymatic study	Masson M (1997), Masson M (1997), Masson M (1997), Zilio N (2013), Matafora V (2009), Zilio N (2013), Gocke CB (2005)	7
CHFR	5	PCNA	0	affinity chromatography technology	Oh YM (2009)	1
UBE2D2	0	TRIM25	5	two hybrid, pull down, pull down, pull down, affinity chromatography technology	Markson G (2009), Nakajima A (2007), Ronchi VP (2012), Sanchez JG (2016), Choudhury NR (2017)	5
UBE2D3	1	CHFR	5	two hybrid, pull down, pull down	Markson G (2009), Chaturvedi P (2002), Liu C (2013)	3
CBLC	1	UBE2D2	0	pull down, pull down	Ryan PE (2010), Kim M (2004)	2
CHFR	5	PML	7	fluorescent resonance energy transfe	Daniels MJ (2004)	1
HDAC1	4	SIN3A	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Yao YL (2003), Yao YL (2003), Fleischer TC (2003), Fleischer TC (2003), Yang L (2003), Grozinger CM (1999), Zhang J (2002), Zhang J (2002), You A (2001), Zhang Y (1999), Zhang Y (2002), Tong JK (1998), Hassig CA (1998), Yasui D (2002), Huang EY (2000), Huang EY (2000), Kuzmichev A (2002), Kuzmichev A (2002), Martinowich K (2003), Martinowich K (2003), Suzuki M (2003), Suzuki M (2006), Nakamura T (2002), Wei Q (2005), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Skowyra D (2001), Humphrey GW (2001), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Sun JM (2007), Karwowska-Desaulniers P (2007), Terhune SS (2010), Xue Y (1998), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Oh YM (2009), Wan C (2015), Hein MY (2015), Hsu DS (2014), Huttlin EL (2017)	45
USP7	14	HLTF	7	affinity chromatography technology	Sowa ME (2009)	1
UBE2W	0	DTX3	4	two hybrid	Markson G (2009)	1
SMARCB1	1	VIM	0	two hybrid	Daakour S (2016)	1
UBE2D1	0	RELA	1	enzymatic study	Ryo A (2003)	1
PLK1	0	RELA	1	pull down	Lin DC (2011)	1
AURKA	1	HDAC2	1	pull down	Pugacheva EN (2007)	1
UBE2E2	1	CHFR	5	two hybrid	Markson G (2009)	1
UBE2D4	0	TRIM25	5	two hybrid	Markson G (2009)	1
UBE2I	0	HDAC1	4	enzymatic study	Citro S (2013)	1
HDAC1	4	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology	Hakimi MA (2002), Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Fischle W (2002), Johnson CA (2002), Fischle W (2001), Fischer DD (2002), Fischer DD (2002), Ashburner BP (2001), Zhang Y (1999), Tong JK (1998), Tong JK (1998), Hassig CA (1998), Hassig CA (1998), Zhang Y (1997), van der Vlag J (1999), van der Vlag J (1999), Noh EJ (2009), Noh EJ (2009), Galasinski SC (2002), Galasinski SC (2002), Galasinski SC (2002), He S (2005), Humphrey GW (2001), Park JH (2004), Park JH (2004), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Martinez FP (2012), Martinez FP (2012), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Joshi P (2013), Schnur N (2007), Schnur N (2007), Oh YM (2009), Wan C (2015), Hein MY (2015), Chen TC (2014), Huttlin EL (2017)	48
MCM2	3	TRIM25	5	affinity chromatography technology	Drissi R (2015)	1
UBE2D2	0	RNF7	0	two hybrid, pull down	Markson G (2009), Kershaw NJ (2014)	2
UBE2I	0	UBE2E1	1	biochemical	Wan C (2015)	1
DTX3	4	CHFR	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CBLC	1	CHFR	5	two hybrid	Woodsmith J (2012)	1
UBE2D4	0	DTX3	4	two hybrid	Markson G (2009)	1
CHFR	5	PLK1	0	enzymatic study, affinity chromatography technology	Kang D (2002), Oh YM (2009)	2
HDAC1	4	PML	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Khan MM (2001), Khan MM (2001), Wu WS (2001), Wu WS (2001), Wu WS (2001), Wu WS (2001), Wu WS (2001), Morey L (2008), Kuo HY (2013), Kim YE (2015)	10
MCM2	3	PLK1	0	affinity chromatography technology	Boldt K (2016)	1
CDC20	1	PCNA	0	affinity chromatography technology	Craney A (2016)	1
SIRT1	3	EEF1G	0	affinity chromatography technology	Law IK (2009)	1
UBE2D2	0	RELA	1	enzymatic study	Ryo A (2003)	1
UBE2E2	1	HDAC2	1	affinity chromatography technology	Kraemer OH (2008)	1
UBE2I	0	PML	7	enzymatic study, pull down, enzymatic study, two hybrid, two hybrid, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, pull down	Knipscheer P (2008), Kim YE (2005), Satow R (2012), Duprez E (1999), Wang J (2011), Tatham MH (2003), Duprez E (1999), Gocke CB (2005), Lin DY (2006), Jo S (2016), Schilling EM (2017)	11
HLTF	7	UBE2N	1	affinity chromatography technology, pull down, pull down, enzymatic study	Unk I (2008), Unk I (2008), Masuda Y (2012), Masuda Y (2012)	4
UBE2E3	0	DTX3	4	two hybrid	Markson G (2009)	1
UBE2E3	0	CHFR	5	two hybrid	Markson G (2009)	1
UBE2D1	0	TRIM25	5	two hybrid, pull down, pull down, pull down, pull down	Markson G (2009), Gack MU (2007), Wang Y (2014), Ronchi VP (2012), Wang S (2016)	5
CHFR	5	HLTF	7	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Kim JM (2010), Kim JM (2010), Kim JM (2010), Oh YM (2009)	4
UBE2I	0	CHFR	5	enzymatic study	Kwon YE (2013)	1
RELA	1	PARP1	3	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Hassa PO (2001), Hassa PO (2001), Hassa PO (2005), Hassa PO (2005), Hassa PO (2008), Hassa PO (2008)	6
UBE2W	0	CHFR	5	two hybrid	Markson G (2009)	1
SIRT1	3	RELA	1	affinity chromatography technology	Yang SR (2007)	1
UBE2D1	0	DTX3	4	two hybrid	Markson G (2009)	1
GRB14	1	CHFR	5	affinity chromatography technology, pull down	Perdereau D (2015), Perdereau D (2015)	2
TRIM25	5	CHFR	5	affinity chromatography technology	Choudhury NR (2017)	1
PLK1	0	HDAC2	1	affinity chromatography technology	Boldt K (2016)	1
UBE2D3	1	DTX3	4	two hybrid	Markson G (2009)	1
CHFR	5	CDC20	1	affinity chromatography technology	Oh YM (2009)	1
MCM2	3	UBE2D2	0	affinity chromatography technology	Drissi R (2015)	1
UBE2D3	1	TRIM25	5	two hybrid, pull down, pull down, affinity chromatography technology	Markson G (2009), Ronchi VP (2012), Choudhury NR (2017), Choudhury NR (2017)	4
PARP1	3	PCNA	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Frouin I (2003), Cazzalini O (2010), Cazzalini O (2010), Lee CH (2010), Pozo FM (2011), Sekimoto T (2010)	6
CDC20	1	PLK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Sedgwick GG (2012), Hyun SY (2013), Hyun SY (2013), Hyun SY (2013), Jia L (2016)	5
CHFR	5	RANBP2	9	affinity chromatography technology	Oh YM (2009)	1
TRIM25	5	PLK1	0	affinity chromatography technology	Choudhury NR (2017)	1
CHFR	5	TRIM9	3	two hybrid	Woodsmith J (2012)	1
SIRT1	3	PARP1	3	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Rajamohan SB (2009), Rajamohan SB (2009), Rajamohan SB (2009), Rajamohan SB (2009)	4
CHFR	5	SIN3A	13	affinity chromatography technology	Oh YM (2009)	1
SMARCD1	5	SMARCB1	1	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Ito T (2008), Mak AB (2010), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	6
MCM2	3	VIM	0	affinity chromatography technology	Drissi R (2015)	1
TRIM25	5	PCNA	0	affinity chromatography technology, affinity chromatography technology	Park JM (2014), Park JM (2014)	2
PARP1	3	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Hassa PO (2005), Hassa PO (2005), Hang CT (2010), Rajamohan SB (2009)	4
CHFR	5	VIM	0	affinity chromatography technology	Oh YM (2009)	1
USP7	14	UBE2D3	1	enzymatic study	Zhang ZM (2015)	1
HDAC2	1	PML	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wu WS (2001), Morey L (2008), Kraemer OH (2008), Kim YE (2015)	4
UBE2N	1	CHFR	5	two hybrid, pull down	Markson G (2009), Liu C (2013)	2
AURKA	1	UBE2N	1	pull down, affinity chromatography technology, enzymatic study	Ewart-Toland A (2003), Ewart-Toland A (2003), Briassouli P (2006)	3
UBE2D2	0	CHFR	5	two hybrid, pull down, pull down, pull down	Markson G (2009), Kang D (2002), Oh YM (2009), Chaturvedi P (2002)	4
PML	7	RELA	1	affinity chromatography technology, affinity chromatography technology	Wu WS (2003), Chen Y (2015)	2
UBE2D3	1	PCNA	0	enzymatic study	Hibbert RG (2012)	1
UBE2W	0	RNF125	0	two hybrid	Markson G (2009)	1
CHFR	5	EEF1G	0	two hybrid	Stelzl U (2005)	1
UBE2D2	0	DTX3	4	two hybrid	Markson G (2009)	1
UBE2E2	1	RNF125	0	two hybrid	Markson G (2009)	1
RNF125	0	PML	7	two hybrid	Woodsmith J (2012)	1
GRB10	4	CHFR	5	pull down	Perdereau D (2015)	1
SMARCB1	1	HDAC1	4	biochemical	Sif S (2001)	1
MCM2	3	UBE2D3	1	affinity chromatography technology	Drissi R (2015)	1
UBE2E1	1	DTX3	4	two hybrid	Markson G (2009)	1
CHFR	5	283556	0	pull down	Kang D (2002)	1
CDC20	1	HDAC1	4	affinity chromatography technology, biochemical	Yoon YM (2004), Yoon YM (2004)	2
UBE2I	0	UBE2D2	0	biochemical	Wan C (2015)	1
UBE2N	1	RNF125	0	two hybrid	Markson G (2009)	1
CHFR	5	RELA	1	affinity chromatography technology, affinity chromatography technology	Kashima L (2009), Kashima L (2009)	2
RELA	1	HDAC2	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Kiernan R (2003), Yu Z (2002), Yu Z (2002), Ito K (2001), Ito K (2000), Sun JM (2007), Adenuga D (2010), Wang H (2010), Chen TC (2014)	9
UBE2I	0	CBLC	1	two hybrid	Markson G (2009)	1
PML	7	SIN3A	13	pull down, affinity chromatography technology	Khan MM (2001), Khan MM (2001)	2
UBE2E1	1	CHFR	5	two hybrid	Markson G (2009)	1
TRIM25	5	USP7	14	affinity chromatography technology	Choudhury NR (2017)	1
UBE2I	0	AURKA	1	enzymatic study	Ban R (2011)	1
UBE2D4	0	RNF7	0	two hybrid	Markson G (2009)	1
CHFR	5	SIRT1	3	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Kim M (2016), Kim M (2016), Kim M (2016), Kim M (2016)	4
RELA	1	USP7	14	affinity chromatography technology, affinity chromatography technology, enzymatic study	Colleran A (2013), Colleran A (2013), Colleran A (2013)	3
UBE2D1	0	UBE2D2	0	biochemical	Havugimana PC (2012)	1
UBE2N	1	VIM	0	affinity chromatography technology	Boldt K (2016)	1
AURKA	1	CHFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Privette LM (2008), Oh YM (2009), Oh YM (2009)	3
MCM2	3	EEF1G	0	affinity chromatography technology	Drissi R (2015)	1
CDC20	1	MAD2L1	0	affinity chromatography technology, two hybrid, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, unspecified method, pull down, affinity chromatography technology	Zhang Y (2001), Sihn CR (2003), Luo X (2000), Sironi L (2001), DAngiolella V (2003), Kallio MJ (2002), Wassmann K (1998), Kallio M (1998), Fang G (1998), Fang G (1998), Skoufias DA (2001), Nilsson J (2008), Privette LM (2008), Stegmeier F (2007), Ho CY (2010), Ho CY (2010), Mansfeld J (2011), Gao YF (2011), Braunstein I (2007), Visconti R (2010), Ma HT (2011), Townsend K (2009), Lee YJ (2008), DAngiolella V (2003), Tang Z (2001), Tang Z (2001), Sironi L (2001), Sironi L (2001), Ge S (2009), Mapelli M (2007), Tipton AR (2011), Mondal G (2006), Mondal G (2006), Westhorpe FG (2011), De Antoni A (2005), De Antoni A (2005), Kwan PS (2013), Katayama H (2012), Fava LL (2011), Santaguida S (2011), Mapelli M (2006), Eytan E (2013), Eytan E (2013), Hyun SY (2013), Han JS (2013), Rodriguez-Bravo V (2014), Fogeron ML (2013), Wang K (2014), Eytan E (2014), Hein JB (2014), Yen AH (2010), Yen AH (2010), Di Fiore B (2015), Hein MY (2015), Voets E (2015), Lischetti T (2014), Tipton AR (2013), Boekhout M (2015), Kelly A (2014), Craney A (2016), Sedgwick GG (2016), Sedgwick GG (2016), Izawa D (2012), Izawa D (2012), Jia L (2016), Jia L (2016), Kaisari S (2017), Yang M (2008), Kim S (2010), Kim S (2010)	70
CBLC	1	UBE2D1	0	pull down	Kim M (2004)	1
CHFR	5	MCM2	3	affinity chromatography technology	Oh YM (2009)	1
SMARCB1	1	SMARCA4	19	biochemical, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, genetic interference, affinity chromatography technology, affinity chromatography technology	Sif S (2001), Sullivan EK (2001), Wang W (1996), Wang W (1996), Otsuki T (2001), Zhao K (1998), Reyes JC (1997), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Pal S (2003), Bultman SJ (2005), Gong F (2008), Medjkane S (2004), Ito T (2008), Sif S (1998), Dallas PB (1998), Tando T (2010), Bakshi R (2010), Bakshi R (2010), Mahmoudi T (2006), Mahmoudi T (2006), Bartlett C (2011), Nishimoto N (2012), Havugimana PC (2012), Wan C (2015), Shen JP (2017), Pchelintsev NA (2013), Pchelintsev NA (2013)	30
PML	7	SIRT1	3	affinity chromatography technology, pull down	Langley E (2002), Langley E (2002)	2
PML	7	AURKA	1	affinity chromatography technology, affinity chromatography technology	Xu ZX (2005), Xu ZX (2005)	2
CHFR	5	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Oh YM (2009), Oh YM (2009), Oh YM (2009), Oh YM (2009), Oh YM (2009)	5
RNF7	0	CHFR	5	two hybrid	Woodsmith J (2012)	1
PML	7	RANBP2	9	affinity chromatography technology	Satow R (2012)	1
CBLC	1	UBE2D3	1	pull down	Kim M (2004)	1
CHFR	5	PARP1	3	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kashima L (2012), Kashima L (2012), Ahel I (2008), Oh YM (2009), Liu C (2013), Brodie SA (2015), Brodie SA (2015)	7
PCNA	0	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology	Milutinovic S (2002), Milutinovic S (2002), Naryzhny SN (2004)	3
TRIM25	5	SIN3A	13	affinity chromatography technology	Choudhury NR (2017)	1
CDC20	1	AURKA	1	affinity chromatography technology, affinity chromatography technology	Farruggio DC (1999), Katayama H (2012)	2
MCM2	3	UBE2D4	0	affinity chromatography technology	Drissi R (2015)	1
HDAC1	4	SMARCA4	19	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Qiu Z (2008), Battaglioli E (2002), Hang CT (2010), DiRenzo J (2000)	4
SMARCD1	5	SMARCA4	19	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Hsiao PW (2003), Pal S (2003), Ito T (2008), Tando T (2010), Mak AB (2010), Oh J (2008), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	10
HLTF	7	PCNA	0	affinity chromatography technology, enzymatic study, enzymatic study	Unk I (2008), Masuda Y (2012), Achar YJ (2015)	3
SMARCB1	1	HDAC2	1	biochemical, biochemical	Sif S (2001), Havugimana PC (2012)	2
SIRT1	3	HDAC2	1	affinity chromatography technology	Law IK (2009)	1
UBE2D4	0	CHFR	5	two hybrid	Markson G (2009)	1
KIF22	1	CHFR	5	affinity chromatography technology, affinity chromatography technology	Maddika S (2009), Maddika S (2009)	2
UBE2N	1	TRIM25	5	two hybrid, pull down, x-ray crystallography, affinity chromatography technology	Markson G (2009), Sanchez JG (2016), Sanchez JG (2016), Choudhury NR (2017)	4
PARP1	3	HDAC2	1	affinity chromatography technology, pull down, affinity chromatography technology	Hassa PO (2005), Hassa PO (2005), Hang CT (2010)	3
SMARCA4	19	PML	7	imaging technique	Chuang YS (2011)	1
RNF125	0	CHFR	5	two hybrid	Woodsmith J (2012)	1
SMARCD1	5	CHFR	5	affinity chromatography technology, affinity chromatography technology, enzymatic study	Jung I (2012), Jung I (2012), Jung I (2012)	3
TRIM25	5	SMARCA4	19	affinity chromatography technology	Choudhury NR (2017)	1
UBE2E2	1	DTX3	4	two hybrid	Markson G (2009)	1
SMARCA4	19	SIN3A	13	biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sif S (2001), Sif S (2001), Kuzmichev A (2002), Kuzmichev A (2002), Qiu Z (2008), Xu Z (2006), Pal S (2003), Pal S (2003)	8
MCM2	3	UBE2D1	0	affinity chromatography technology	Drissi R (2015)	1
UBE2D1	0	RNF125	0	two hybrid, pull down, pull down	Markson G (2009), Bijlmakers MJ (2011), Bijlmakers MJ (2016)	3
RNF7	0	UBE2D3	1	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Tan M (2010), Kershaw NJ (2014), Raducu M (2016), Kuang P (2016), Kuang P (2016)	5
UBE2I	0	RANBP2	9	affinity chromatography technology, pull down, two hybrid, pull down, x-ray crystallography, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Zhang H (2002), Bandyopadhyay S (2010), Werner A (2012), Tatham MH (2005), Saitoh H (2002), Saitoh H (2002), Gareau JR (2012), Hein MY (2015), Sarkar K (2015), Huttlin EL (2017)	11
USP7	14	CHFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Oh YM (2007), Oh YM (2009), Oh YM (2009)	3
UBE2E3	0	USP7	14	affinity chromatography technology	Huttlin EL (2017)	1
TRIM25	5	PML	7	affinity chromatography technology	Choudhury NR (2017)	1
UBE2D4	0	RNF125	0	two hybrid	Markson G (2009)	1
C5orf24	0	CHFR	5	affinity chromatography technology	Huttlin EL (2017)	1
USP7	14	PML	7	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Sivachandran N (2010), Sarkari F (2011), Sarkari F (2011), Hein MY (2015)	4
LRP1	25	CHFR	5	affinity chromatography technology	Cal R (2013)	1
HDAC1	4	VIM	0	affinity chromatography technology	Terhune SS (2010)	1
SMARCA4	19	CHFR	5	affinity chromatography technology, affinity chromatography technology, enzymatic study	Jung I (2012), Jung I (2012), Jung I (2012)	3
AURKA	1	PLK1	0	affinity chromatography technology, biochemical	Katayama H (2008), Havugimana PC (2012)	2
SMARCB1	1	SIN3A	13	biochemical, pull down, affinity chromatography technology	Sif S (2001), Pal S (2003), Nakamura T (2002)	3
HDAC2	1	SIN3A	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang Y (2003), Fleischer TC (2003), Fleischer TC (2003), Hakimi MA (2003), Yang L (2003), Laherty CD (1997), Zhang Y (2002), Tong JK (1998), Zhang Y (2005), Nakamura T (2002), Sekhavat A (2007), Zou J (2004), Sun JM (2007), Xue Y (1998), Tsai SC (2002), Brandl A (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hsu DS (2014)	20
SIRT1	3	UBE2I	0	enzymatic study	Hsieh YL (2013)	1
USP7	14	UBE2E1	1	unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Sarkari F (2013), Sarkari F (2013), Sarkari F (2013), Sarkari F (2013), Sarkari F (2013), Wheaton K (2017)	6