PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
ELAVL1	0	SEPHS1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
SERPINH1	2	NSG2	0	two hybrid	Vinayagam A (2011)	1
ACP6	0	SLC35F6	0	two hybrid	Stelzl U (2005)	1
SUCO	1	SLC35F6	0	affinity chromatography technology	Hein MY (2015)	1
ACP5	1	SLC35F6	0	two hybrid	Stelzl U (2005)	1
MS4A7	0	SLC35F6	0	two hybrid	Stelzl U (2005)	1
ELAVL1	0	SLC35F6	0	affinity chromatography technology	Abdelmohsen K (2009)	1
NDUFA4L2	0	SLC35F6	0	two hybrid	Stelzl U (2005)	1
SEC11A	0	SLC35F6	0	two hybrid	Stelzl U (2005)	1
ATP6AP2	2	SLC35F6	0	affinity chromatography technology	Hein MY (2015)	1
KIAA0087	0	SLC35F6	0	two hybrid	Stelzl U (2005)	1
NSG2	0	SLC35F6	0	two hybrid	Stelzl U (2005)	1
SEPHS1	0	SLC35F6	0	two hybrid	Stelzl U (2005)	1
PSMG2	1	SLC35F6	0	two hybrid	Stelzl U (2005)	1
SERPINH1	2	SLC35F6	0	two hybrid	Stelzl U (2005)	1
TTC30B	2	SLC35F6	0	affinity chromatography technology	Boldt K (2016)	1
ELAVL1	0	TMEM63B	1	affinity chromatography technology	Abdelmohsen K (2009)	1
OAT	4	SLC35F6	0	two hybrid	Stelzl U (2005)	1
TMEM63B	1	SLC35F6	0	affinity chromatography technology	Hein MY (2015)	1
ELAVL1	0	SERPINH1	2	affinity chromatography technology	Abdelmohsen K (2009)	1
KRBOX4	0	SLC35F6	0	affinity chromatography technology	Hein MY (2015)	1
ALDH2	2	SLC35F6	0	two hybrid	Stelzl U (2005)	1
TCEAL4	0	SLC35F6	0	affinity chromatography technology	Hein MY (2015)	1
KIAA0232	4	SLC35F6	0	two hybrid	Stelzl U (2005)	1
TOMM40	1	SLC35F6	0	affinity chromatography technology	Hein MY (2015)	1
SERPINH1	2	TOMM40	1	biochemical	Havugimana PC (2012)	1
ATP6V1B1	4	SLC35F6	0	affinity chromatography technology	Nylandsted J (2011)	1
NES	2	SLC35F6	0	affinity chromatography technology	Hein MY (2015)	1
MBOAT1	1	SLC35F6	0	affinity chromatography technology	Hein MY (2015)	1