Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
TEX10	rs7035619	A	duloxetine	efficacy	yes	Variant was suggestively significant, but did not reach genome-wide significance. Response was defined by >50% decrease in Montgomery-Asberg Depression Rating Scale (MADRS) score at the end of treatment.	Allele A is associated with increased response to duloxetine in people with Depressive Disorder, Major as compared to allele T.	29407288	1449167906
TEX10	rs7472	G	duloxetine	efficacy	yes	Variant was suggestively significant, but did not reach genome-wide significance. Response was defined by >50% decrease in Montgomery-Asberg Depression Rating Scale (MADRS) score at the end of treatment.	Allele G is associated with increased response to duloxetine in people with Depressive Disorder, Major as compared to allele A.	29407288	1449167912
TEX10	rs10124893	G	duloxetine	efficacy	yes	Variant was suggestively significant, but did not reach genome-wide significance. Response was defined by >50% decrease in Montgomery-Asberg Depression Rating Scale (MADRS) score at the end of treatment.	Allele G is associated with increased response to duloxetine in people with Depressive Disorder, Major as compared to allele A.	29407288	1449167888
TEX10	rs10989064	T	duloxetine	efficacy	yes	Variant was suggestively significant, but did not reach genome-wide significance. Response was defined by >50% decrease in Montgomery-Asberg Depression Rating Scale (MADRS) score at the end of treatment.	Allele T is associated with increased response to duloxetine in people with Depressive Disorder, Major as compared to allele C.	29407288	1449167894
TEX10	rs6479008	C	duloxetine	efficacy	yes	Variant was suggestively significant, but did not reach genome-wide significance. Response was defined by >50% decrease in Montgomery-Asberg Depression Rating Scale (MADRS) score at the end of treatment.	Allele C is associated with increased response to duloxetine in people with Depressive Disorder, Major as compared to allele A.	29407288	1449167900