Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications
TET2	54790	DECITABINE	CHEMBL1201129		CKB	25224413
TET2	54790	AZACITIDINE	CHEMBL1489		CKB	21494260, 25224413

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
TET2	rs12505746	A	hydrochlorothiazide	efficacy	no	The SNP was discovered in two independent cohorts, although no SNPs reached genome wide significance. The authors then considered P<1 x10^-5 as a threshold for significance (based on the results from a Q-Q plot distribution reference line). Using this revised threshold the authors reported that this SNP was associated with a lower decrease in systolic blood pressure after hydrochlorothiazide treatment.	Allele A is associated with decreased response to hydrochlorothiazide in people with Essential hypertension as compared to allele G.	25695618	1444703568