Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
PON2 rs2299267 G antidepressants efficacy yes Identity of minor allele not specified, so minor allele of dbSNP used here (G). Response considered to be successful with a 50% reduction at discharge of the Hamilton Rating Scale for Depression (HRSD17). Patients measured at admission and discharge, 4-6 weeks later. Specific antidepressants not listed. Allele G is associated with decreased response to antidepressants in people with Depressive Disorder, Major as compared to allele A. 27091189 1447983326