PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
SIRT7	1	APP	1	pull down	Olah J (2011)	1
BRCA1	7	TUBB	3	affinity chromatography technology, affinity chromatography technology	Lotti LV (2002), Ertych N (2016)	2
MYC	2	POLH	1	genetic interference	Toyoshima M (2012)	1
POLH	1	AHNAK	15	affinity chromatography technology	Huttlin EL (2017)	1
PCNA	0	POLD2	2	pull down, pull down, far western blotting, biochemical, affinity chromatography technology, affinity chromatography technology	Lu X (2002), Lu X (2002), Lu X (2002), Shikata K (2001), Cazzalini O (2014), Hein MY (2015)	6
BRCA1	7	MYC	2	affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Li H (2002), Xiong J (2003), Xiong J (2003), Wang Q (1998), Wang Q (1998), Wang Q (1998), Harte MT (2010), Harte MT (2010), Xiong J (2003), Xiong J (2003), Zhou C (2003)	11
PALB2	3	POLH	1	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Buisson R (2014), Buisson R (2014), Buisson R (2014), Buisson R (2014)	4
POLH	1	TUBB	3	affinity chromatography technology	Yuasa MS (2006)	1
SIRT7	1	CENPF	5	affinity chromatography technology	Tsai YC (2012)	1
BRCA1	7	TUBA4A	1	affinity chromatography technology	Ertych N (2016)	1
SIRT7	1	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Tsai YC (2012), Jiang L (2017), Jiang L (2017), Jiang L (2017), Jiang L (2017), Jiang L (2017)	6
POLH	1	FRYL	12	affinity chromatography technology	Hein MY (2015)	1
MYC	2	REV1	1	genetic interference	Toyoshima M (2012)	1
HSP90AA1	7	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Johnson N (2013), Johnson N (2013), Ertych N (2016)	3
MDM2	2	UBC	7	pull down, enzymatic study, enzymatic study	Higashitsuji H (2005), Luo J (2013), Poyurovsky MV (2007)	3
RCHY1	0	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Corcoran CA (2009), Wang L (2011), Wang L (2011), Corcoran CA (2009)	4
HSP90AA1	7	APP	1	affinity chromatography technology	Kumar P (2007)	1
FANCD2	3	BRCA1	7	two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Reuter TY (2003), Vandenberg CJ (2003), Garcia-Higuera I (2001), Garcia-Higuera I (2001), Loke J (2015)	5
POLH	1	USP7	14	affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study	Qian J (2014), Qian J (2014), Qian J (2014), Qian J (2014), Qian J (2014)	5
POLH	1	BRCA1	7	affinity chromatography technology	Tian F (2013)	1
HSP90AA1	7	MYC	2	affinity chromatography technology	Carystinos GD (2003)	1
PCNA	0	PACSIN3	2	biochemical	Wan C (2015)	1
DHX16	5	LSM5	1	biochemical	Havugimana PC (2012)	1
POLI	5	REV1	1	two hybrid, two hybrid, pull down	Ohashi E (2004), Ohashi E (2009), Ohashi E (2009)	3
RAD18	3	SPRTN	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Centore RC (2012), Centore RC (2012), Ghosal G (2012), Ghosal G (2012)	4
PALB2	3	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang F (2009), Sy SM (2009), Zhang F (2009), Zhang F (2009), Zhang F (2009), Sy SM (2009), Sy SM (2009), Sy SM (2009), Sy SM (2009), Sy SM (2009), Zhang F (2012), Johnson N (2013), Anantha RW (2013), Hill SJ (2014), Bleuyard JY (2012), Orthwein A (2015), Orthwein A (2015), Loke J (2015), Simhadri S (2014), Ma J (2012), Ma J (2012), Foo TK (2017)	22
POLH	1	ACTB	8	affinity chromatography technology	Huttlin EL (2017)	1
POLH	1	UBE2B	3	affinity chromatography technology, affinity chromatography technology	Yuasa MS (2006), Yuasa MS (2006)	2
SPRTN	0	MLH1	6	affinity chromatography technology	Mosbech A (2012)	1
TUBA4A	1	TUBB	3	biochemical, biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	3
PCNA	0	REV1	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Pozo FM (2011), Pozo FM (2011), Qin Z (2013), Shim HS (2015)	4
UBC	7	UBE2B	3	affinity chromatography technology, affinity chromatography technology	Bish RA (2007), Hong JH (2015)	2
BRCA1	7	PCNA	0	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
BRCA2	6	PCNA	0	affinity chromatography technology	Brough R (2012)	1
MLH1	6	PCNA	0	far western blotting, pull down	Dzantiev L (2004), Genschel J (2017)	2
POLH	1	MLH1	6	two hybrid, pull down, affinity chromatography technology	Kanao R (2009), Kanao R (2009), Kanao R (2009)	3
BRCA1	7	RAD18	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian F (2013), Tian F (2013), Hill SJ (2014)	3
LGR4	3	UBC	7	affinity chromatography technology	Carmon KS (2014)	1
MDM2	2	TUBB	3	affinity chromatography technology	Frum R (2007)	1
POLI	5	UBC	7	two hybrid, two hybrid, far western blotting, x-ray crystallography, pull down, far western blotting	Plosky BS (2006), Plosky BS (2006), McIntyre J (2012), Bomar MG (2010), Plosky BS (2006), McIntyre J (2012)	6
POLH	1	ACTBL2	0	affinity chromatography technology	Huttlin EL (2017)	1
REV1	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Pozo FM (2011), Pozo FM (2011)	2
FANCD2	3	BRCA2	6	imaging technique, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Wang X (2004), Wang X (2004), Hussain S (2004), Hussain S (2004), Hejna J (2008), Wilson JB (2010), Wilson JB (2010), Wilson JB (2008), Wilson JB (2008), Wang X (2004), Zhi G (2009), Zhi G (2009), Siddiqui MQ (2017), Siddiqui MQ (2017), Siddiqui MQ (2017)	15
TRAIP	0	APP	1	pull down	Olah J (2011)	1
HSP90AA1	7	TUBB	3	affinity chromatography technology	Skarra DV (2011)	1
LGR4	3	TUBA1B	0	affinity chromatography technology	Carmon KS (2014)	1
UBE2B	3	PCNA	0	enzymatic study, enzymatic study	Masuda Y (2010), Watanabe K (2004)	2
NXF1	0	TUBA4A	1	affinity chromatography technology	Castello A (2012)	1
TUBB	3	MYC	2	affinity chromatography technology	Conacci-Sorrell M (2010)	1
REV1	1	BRCA1	7	affinity chromatography technology	Tian F (2013)	1
FANCD2	3	MLH1	6	affinity chromatography technology	Williams SA (2011)	1
POLH	1	RAD18	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Yuasa MS (2006), Yuasa MS (2006), Day TA (2010), Watanabe K (2004), Watanabe K (2004), Watanabe K (2004), Lin JR (2011), Durando M (2013)	8
POLH	1	DHX16	5	affinity chromatography technology	Hein MY (2015)	1
PCBP1	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BRCA2	6	POLH	1	affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Buisson R (2014), Buisson R (2014), Buisson R (2014), Buisson R (2014)	4
APP	1	MYC	2	pull down	Virok DP (2011)	1
MDM2	2	SIRT7	1	affinity chromatography technology	Nihira NT (2017)	1
POLH	1	TUBA4A	1	affinity chromatography technology	Huttlin EL (2017)	1
POLH	1	POTEI	0	affinity chromatography technology	Huttlin EL (2017)	1
WBP2	0	POLH	1	two hybrid	Lim SK (2016)	1
FANCD2	3	RAD18	3	affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, biochemical	Williams SA (2011), Williams SA (2011), Park HK (2010), Chen X (2016), Chen X (2016)	5
POLH	1	MDM2	2	affinity chromatography technology	Jung YS (2012)	1
PCBP1	2	POLH	1	affinity chromatography technology	Ren C (2014)	1
LGR4	3	POLH	1	affinity chromatography technology	Carmon KS (2014)	1
BRCA2	6	BRCA1	7	affinity chromatography technology, two hybrid, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sarkisian CJ (2001), Reuter TY (2003), Dong Y (2003), Chen J (1998), Chen J (1998), Villarroel MC (2011), Kumaraswamy E (2007), Sy SM (2009), Sy SM (2009), Sy SM (2009), Johnson N (2013), Hill SJ (2014), Loke J (2015)	13
SIRT7	1	NXF1	0	affinity chromatography technology	Tsai YC (2012)	1
PCNA	0	FANCD2	3	affinity chromatography technology, affinity chromatography technology, pull down, biochemical	Howlett NG (2009), Howlett NG (2009), Howlett NG (2009), Chen X (2016)	4
MYC	2	ACTB	8	biochemical	Park J (2002)	1
POLH	1	KNL1	5	affinity chromatography technology	Hein MY (2015)	1
POLH	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, biochemical	Sekimoto T (2010), Sekimoto T (2010), Sekimoto T (2010)	3
UBC	7	FANCD2	3	pull down, affinity chromatography technology	Rego MA (2012), Yamamoto KN (2011)	2
BRCA1	7	MLH1	6	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Cannavo E (2007), Suhasini AN (2011), Hill SJ (2014)	4
TUBA1B	0	TUBB	3	biochemical	Havugimana PC (2012)	1
MYC	2	MLH1	6	two hybrid, two hybrid, pull down, affinity chromatography technology	Mac Partlin M (2003), Mac Partlin M (2003), Mac Partlin M (2003), Mac Partlin M (2003)	4
NXF1	0	AHNAK	15	affinity chromatography technology	Castello A (2012)	1
BRCA1	7	RCHY1	0	affinity chromatography technology	Ertych N (2016)	1
USP7	14	MYC	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Tavana O (2016), Tavana O (2016), Tavana O (2016), Tavana O (2016)	4
SPRTN	0	POLH	1	affinity chromatography technology, affinity chromatography technology	Ghosal G (2012), Ghosal G (2012)	2
WBP2	0	UBC	7	two hybrid	Lim SK (2016)	1
USP7	14	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, unspecified method, biochemical, x-ray crystallography, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lu X (2007), Becker K (2007), Pereg Y (2006), Hu M (2006), Hu M (2006), Hu M (2006), Hu M (2006), Sarkari F (2010), Sarkari F (2010), Tang J (2006), Tang J (2006), Ma J (2010), Song MS (2008), Sheng Y (2006), Sheng Y (2006), Sheng Y (2006), Ye M (2015), Lim KH (2015), Reddy BA (2014), Rouge L (2016), Nihira NT (2017), Nihira NT (2017), Mungamuri SK (2016), Mungamuri SK (2016), Sun Y (2017)	25
PALB2	3	BRCA2	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Hayakawa T (2010), Zhang F (2009), Sy SM (2009), Zhang F (2009), Xia B (2007), Xia B (2006), Xia B (2006), Xia B (2006), Sy SM (2009), Sy SM (2009), Sy SM (2009), Sy SM (2009), Zhang F (2012), Oliver AW (2009), Oliver AW (2009), Oliver AW (2009), Anantha RW (2013), Bleuyard JY (2012), Brough R (2012), Orthwein A (2015), Trego KS (2016), Trego KS (2016), Trego KS (2016), Simhadri S (2014), Byrd PJ (2016), Park JY (2014), Park JY (2014), Ma J (2012), Ma J (2012), Luijsterburg MS (2017), Luijsterburg MS (2017), Foo TK (2017)	32
POLD2	2	POLH	1	two hybrid, pull down	Baldeck N (2015), Baldeck N (2015)	2
NXF1	0	UBC	7	affinity chromatography technology	Castello A (2012)	1
MLH1	6	UBC	7	affinity chromatography technology	Cannavo E (2007)	1
SIRT7	1	FRYL	12	affinity chromatography technology	Tsai YC (2012)	1
POLH	1	TUBA1B	0	affinity chromatography technology	Yuasa MS (2006)	1
FANCD2	3	REV1	1	affinity chromatography technology	Yang Y (2015)	1
RCHY1	0	UBC	7	enzymatic study	Wu G (2010)	1
UBC	7	RAD18	3	affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, pull down, pull down, pull down, pull down, pull down	Matsumoto M (2005), Fenner BJ (2009), Bish RA (2007), Rizzo AA (2014), Rizzo AA (2014), Shereda RD (2010), Shereda RD (2010), Panier S (2012), Ali AM (2012), Thach TT (2015)	10
POLH	1	CENPF	5	affinity chromatography technology	Hein MY (2015)	1
POLH	1	GTPBP2	1	affinity chromatography technology	Hein MY (2015)	1
MYC	2	TUBA4A	1	affinity chromatography technology, affinity chromatography technology	Koch HB (2007), Agrawal P (2010)	2
BRCA1	7	USP7	14	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
SIRT7	1	AHNAK	15	affinity chromatography technology	Tsai YC (2012)	1
MYC	2	MDM2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MDM2	2	HSP90AA1	7	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, biochemical, unspecified method, affinity chromatography technology	Lu TL (2010), Burch L (2004), Burch L (2004), Burch L (2004), Burch L (2004), Burch LR (2004), Okoro DR (2013)	7
POLH	1	SIRT7	1	affinity chromatography technology	Hein MY (2015)	1
MYC	2	FANCD2	3	affinity chromatography technology, imaging technique	Koch HB (2007), Panneerselvam J (2014)	2
PCNA	0	TRAIP	0	affinity chromatography technology, pull down, x-ray crystallography	Hoffmann S (2016), Hoffmann S (2016), Hoffmann S (2016)	3
RAD18	3	PCNA	0	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, enzymatic study, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Song IY (2010), Inagaki A (2011), Kobayashi J (2010), Masuda Y (2010), Watanabe K (2004), Watanabe K (2004), Watanabe K (2004), Notenboom V (2007), Notenboom V (2007), Wong RP (2011), Masuda Y (2012), Unk I (2006), Tomida J (2008), Durando M (2013), Han J (2014), Han J (2014), Han J (2014), Masuda Y (2012), Masuda Y (2015), Guan J (2017)	20
MYC	2	CENPF	5	affinity chromatography technology	Hein MY (2015)	1
UBC	7	POLH	1	pull down, two hybrid, pull down, two hybrid, pull down, affinity chromatography technology	Bienko M (2005), Plosky BS (2006), Sekimoto T (2010), Bienko M (2005), Plosky BS (2006), Ahmed-Seghir S (2015)	6
UBC	7	BRCA1	7	pull down, enzymatic study	Sobhian B (2007), Zhao GY (2007)	2
POLI	5	APP	1	pull down	Olah J (2011)	1
POLH	1	PCNA	0	two hybrid, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe, pull down, pull down, affinity chromatography technology	Haracska L (2001), Haracska L (2001), Kannouche PL (2004), Bienko M (2010), Bienko M (2010), Bienko M (2010), Bienko M (2010), Jung YS (2011), Zlatanou A (2011), Plosky BS (2006), Vidal AE (2004), Sekimoto T (2010), Hibbert RG (2012), Mosbech A (2012), Durando M (2013), Qin Z (2013), Fu D (2013), Fu D (2013), Sekimoto T (2010), Sekimoto T (2010), Sekimoto T (2010), Ahmed-Seghir S (2015), Inoue A (2014), Hedglin M (2016), Hedglin M (2016), Dai X (2016), Guan J (2017)	27
BRCA1	7	PCBP1	2	affinity chromatography technology	Ertych N (2016)	1
MDM2	2	ACTB	8	affinity chromatography technology	Jacob AG (2014)	1
SIRT7	1	DHX16	5	affinity chromatography technology	Tsai YC (2012)	1
USP7	14	RAD18	3	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Zlatanou A (2016), Zlatanou A (2016), Zlatanou A (2016), Zlatanou A (2016)	4
LGR4	3	TUBB	3	affinity chromatography technology	Carmon KS (2014)	1
PCBP1	2	APP	1	pull down	Olah J (2011)	1
POLH	1	PLD1	5	affinity chromatography technology	Hein MY (2015)	1
UBC	7	REV1	1	pull down	Pozo FM (2011)	1
MYC	2	PCBP1	2	affinity chromatography technology	Koch HB (2007)	1
RAD18	3	UBE2B	3	two hybrid, affinity chromatography technology, two hybrid, pull down, two hybrid, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down, biochemical, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Xin H (2000), Xin H (2000), Tateishi S (2000), Tateishi S (2000), Markson G (2009), Hibbert RG (2011), Inagaki A (2011), Watanabe K (2004), Huang A (2011), Huang A (2011), Huang A (2011), Notenboom V (2007), Notenboom V (2007), Song IY (2010), Tomida J (2008), Masuda Y (2010), Han J (2014), Hong JH (2015), Huttlin EL (2017), Foglizzo M (2016)	20
POLH	1	APP	1	pull down	Olah J (2011)	1
POLI	5	POLH	1	two hybrid, far western blotting, two hybrid, far western blotting, affinity chromatography technology	Kannouche P (2003), Kannouche P (2003), McIntyre J (2012), McIntyre J (2012), McIntyre J (2012)	5
RCHY1	0	POLH	1	enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Jung YS (2011), Jung YS (2011), Jung YS (2010), Jung YS (2010)	4
TUBB	3	APP	1	pull down	Olah J (2011)	1
SPRTN	0	UBC	7	pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down	Machida Y (2012), Machida Y (2012), Mosbech A (2012), Mosbech A (2012), Mosbech A (2012), Centore RC (2012), Davis EJ (2012)	7
USP7	14	UBC	7	enzymatic study, enzymatic study, unspecified method, enzymatic study, pull down	Bremm A (2010), Faesen AC (2011), Ernst A (2013), Holowaty MN (2003), Kwasna D (2018)	5
MDM2	2	APP	1	pull down	Miyamoto-Sato E (2010)	1
NXF1	0	POLH	1	affinity chromatography technology	Castello A (2012)	1
BRCA1	7	CENPF	5	affinity chromatography technology	Ertych N (2016)	1
DHX16	5	APP	1	pull down	Olah J (2011)	1
LSM5	1	POLH	1	affinity chromatography technology	Huttlin EL (2017)	1
PCNA	0	MDM2	2	affinity chromatography technology, affinity chromatography technology	Groehler AL (2010), Banks D (2006)	2
POLH	1	REV1	1	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, x-ray crystallography, two hybrid, two hybrid, pull down, two hybrid, pull down, pull down	Yuasa MS (2006), Yuasa MS (2006), Pozo FM (2011), Ohashi E (2004), Ohashi E (2004), Pozhidaeva A (2012), Pozhidaeva A (2012), Tissier A (2004), Tissier A (2004), Ohashi E (2009), Ohashi E (2009), Pustovalova Y (2012)	12
UBE2B	3	MDM2	2	affinity chromatography technology	Chen S (2012)	1
POLH	1	PACSIN3	2	affinity chromatography technology	Hein MY (2015)	1
LGR4	3	ACTB	8	affinity chromatography technology	Carmon KS (2014)	1
BRCA1	7	AHNAK	15	affinity chromatography technology	Ertych N (2016)	1
NXF1	0	HSP90AA1	7	affinity chromatography technology	Castello A (2012)	1
FANCD2	3	POLH	1	affinity chromatography technology, affinity chromatography technology, biochemical	Fu D (2013), Fu D (2013), Fu D (2013)	3
SPRTN	0	POLD2	2	affinity chromatography technology, affinity chromatography technology	Kim MS (2013), Kim MS (2013)	2
SPRTN	0	PCNA	0	imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Centore RC (2012), Centore RC (2012), Ghosal G (2012), Ghosal G (2012), Ghosal G (2012), Ghosal G (2012), Machida Y (2012), Machida Y (2012), Davis EJ (2012), Davis EJ (2012), Juhasz S (2012), Mosbech A (2012), Mosbech A (2012), Mosbech A (2012), Juhasz S (2012), Centore RC (2012)	16
TRAIP	0	POLH	1	two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique	Wallace HA (2014), Wallace HA (2014), Wallace HA (2014), Wallace HA (2014)	4
POLI	5	PCNA	0	two hybrid, x-ray crystallography, two hybrid, affinity chromatography technology, biochemical, far western blotting, affinity chromatography technology, pull down	Plosky BS (2006), Hishiki A (2008), Vidal AE (2004), Vidal AE (2004), Haracska L (2001), McIntyre J (2012), McIntyre J (2012), Boehm EM (2016)	8