PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
LEF1	3	E2F1	0	affinity chromatography technology	Zhou F (2008)	1
EP300	36	SMAD3	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Qiu P (2006), Furumatsu T (2005), Itoh S (2000), Akiyoshi S (1999), Abecassis L (2004), Kaimori A (2010), Janknecht R (1998), Janknecht R (1998), Nishihara A (1999), Nishihara A (1999), Furumatsu T (2005), Ghosh AK (2004), Shen X (1998), Shen X (1998), Ghosh AK (2001), Postigo AA (2003), Postigo AA (2003), Yang WS (2005), Lim JY (2012), Lim JY (2012), Jinnin M (2007), Wang G (2005)	22
SMAD1	0	PIAS4	5	two hybrid, affinity chromatography technology, two hybrid	Long J (2003), Long J (2003), Colland F (2004)	3
PIAS4	5	SMAD7	1	two hybrid, affinity chromatography technology, two hybrid	Imoto S (2003), Imoto S (2003), Colland F (2004)	3
SMAD7	1	CTNNB1	30	affinity chromatography technology, imaging technique, affinity chromatography technology	Edlund S (2005), Edlund S (2005), Tang Y (2008)	3
EP300	36	SMAD4	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology	Kim RH (2000), Luciakova K (2008), Janknecht R (1998), Chung CL (2011), Shen X (1998), Dornan D (2003), Yang Y (2015)	7
PIAS4	5	SMAD3	1	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Imoto S (2003), Long J (2003), Long J (2003), Long J (2003), Long J (2003), Long J (2003)	6
RUVBL1	2	HINT1	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Weiske J (2005), Weiske J (2005), Weiske J (2005), Weiske J (2005)	4
LEF1	3	SMAD3	1	pull down, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology	Labbe E (2000), Labbe E (2000), Cui Q (2005), Cui Q (2005), Cui Q (2005)	5
DAZAP2	1	LEF1	3	affinity chromatography technology, affinity chromatography technology	Lukas J (2009), Lukas J (2009)	2
TLE1	6	HDAC1	4	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ahn JW (2009), Ahn JW (2009), Su L (2012), Su L (2012)	4
KMT5A	2	TCF7L2	12	affinity chromatography technology, pull down, affinity chromatography technology	Li Z (2011), Li Z (2011), Li Z (2011)	3
LEF1	3	ZBTB3	3	two hybrid	Ravasi T (2010)	1
SMAD4	9	SMAD2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Moren A (2003), Wotton D (1999), Mori N (2001), Wu JW (2002), Wu JW (2002), Nakao A (1997), Wicks SJ (2000), Wu JW (2001), Chen X (1997), Hanai J (1999), Lebrun JJ (1999), Poncelet AC (2001), Razani B (2001), Razani B (2001), Wang B (2008), Moren A (2005), Kurisaki K (2003), Prunier C (2003), Kato Y (2002), Xu J (2000), Wang L (2011), He W (2006), He W (2006), Dupont S (2009), Brown JD (1999), Pardali K (2000), Fu G (2011), Chen W (2007), Gao S (2009), Lin X (2003), Seo SR (2006), Brown KA (2008), Brown KA (2008), Halder SK (2005), Barrios-Rodiles M (2005), Barrios-Rodiles M (2005), Dai F (2007), Chacko BM (2004), Chacko BM (2004), Chacko BM (2004), Wu RY (1997), Wu RY (1997), Tomita M (2004), Colland F (2004), Tang Y (2003), Ding L (2009), Fattet L (2013), Wang J (2011), Ali A (2013), Yamakawa N (2002), Yamakawa N (2002), Li X (2015), Zhou F (2014), Yang Y (2015), Yan X (2016), Zhou F (2017)	56
LEF1	3	CDX1	3	affinity chromatography technology, pull down	Beland M (2004), Beland M (2004)	2
EP300	36	E2F1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ji W (2014), Ianari A (2004), Aoki I (2012)	3
HDAC1	4	NFATC1	12	affinity chromatography technology	Nayak A (2009)	1
EP300	36	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Han Y (2008), Mayanil CS (2006), Simone C (2004), Simone C (2004), Simone C (2004), Liu Y (2012), Mizuguchi Y (2012)	7
TCF7L2	12	EP300	36	affinity chromatography technology	Shekhar MP (2006)	1
HDAC1	4	SMAD7	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Simonsson M (2005), Simonsson M (2005), Simonsson M (2005), Laganiere J (2005)	4
NOTCH1	25	DAZAP2	1	two hybrid	Daakour S (2016)	1
NLK	1	MYB	3	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study	Kurahashi T (2005), Kurahashi T (2005), Kurahashi T (2005), Kanei-Ishii C (2004), Kanei-Ishii C (2004)	5
EGLN3	0	NFATC1	12	affinity chromatography technology	Rodriguez J (2016)	1
STAT5A	4	MYB	3	affinity chromatography technology	Fang F (2009)	1
SMAD1	0	SMAD7	1	affinity chromatography technology	Yan X (2016)	1
SMAD2	5	SMAD7	1	genetic interference, pull down, affinity chromatography technology	Lebrun JJ (1999), Zhang S (2007), Yan X (2016)	3
SMAD7	1	SMAD3	1	genetic interference, genetic interference, affinity chromatography technology, protein complementation assay	Datta PK (2000), Lebrun JJ (1999), Yan X (2016), Yan X (2016)	4
LEF1	3	PRMT6	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HDAC1	4	UBTF	8	imaging technique, affinity chromatography technology, biochemical	Ali SA (2012), Ali SA (2012), Ali SA (2012)	3
MYB	3	EP300	36	pull down, imaging technique, affinity chromatography technology, enzymatic study, pull down	Nicot C (2001), Jin W (2011), Sandberg ML (2005), Tomita A (2000), Uttarkar S (2015)	5
DACT1	3	HDAC1	4	affinity chromatography technology	Gao X (2008)	1
SMAD7	1	LEF1	3	affinity chromatography technology, affinity chromatography technology	Edlund S (2005), Cui Q (2005)	2
DACT1	3	LEF1	3	affinity chromatography technology	Gao X (2008)	1
NLK	1	SMAD4	9	two hybrid, affinity chromatography technology	Wang J (2011), Varjosalo M (2013)	2
LEF1	3	HDAC1	4	affinity chromatography technology	Billin AN (2000)	1
CTNNB1	30	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vietor I (2005), Billin AN (2000), Iguchi H (2007), Iioka H (2009)	4
PITX2	1	HDAC1	4	affinity chromatography technology	Kioussi C (2002)	1
TCF7L2	12	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lukas J (2009), Idogawa M (2007), Hong CF (2009), Del Valle-Perez B (2011), Tzeng SL (2006), Tzeng SL (2006), Satow R (2012), Satow R (2012), Graham TA (2001), Sato S (2005), Mosimann C (2006), Shekhar MP (2006), Hsu MC (2007), Loregger A (2015), Hanson AJ (2012), Kuslansky Y (2016)	16
SMAD4	9	SMAD7	1	genetic interference, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Lebrun JJ (1999), Moren A (2005), Moren A (2005), Moren A (2005), Zhang S (2007), Yan X (2016)	6
DAZAP2	1	TLE1	6	two hybrid	Vinayagam A (2011)	1
CTNNB1	30	LEF1	3	affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Edlund S (2005), Grueneberg DA (2003), Behrens J (1996), Behrens J (1996), Labbe E (2000), Sierra J (2006), Gomes NP (2006), Vietor I (2005), Billin AN (2000), Fischer L (2002), Tutter AV (2001), Sadot E (2002), Feigin ME (2008), Daniels DL (2005), Porfiri E (1997), Porfiri E (1997), Hamada F (2004), Vadlamudi U (2005), Lu D (2012), Lu D (2012)	20
SMAD3	1	HDAC1	4	two hybrid, pull down	Liberati NT (2001), Akiyoshi S (1999)	2
DAZAP2	1	CTNNB1	30	affinity chromatography technology	Lukas J (2009)	1
NLK	1	TCF7L2	12	affinity chromatography technology	Ishitani T (2003)	1
LEF1	3	PITX2	1	pull down, pull down	Vadlamudi U (2005), Vadlamudi U (2005)	2
TCF7L2	12	LEF1	3	affinity chromatography technology	Jia Y (2014)	1
NLK	1	LEF1	3	affinity chromatography technology, enzymatic study, enzymatic study, imaging technique	Ishitani T (2003), Li M (2010), Yasuda J (2003), Gupta K (2014)	4
STAT5A	4	HDAC1	4	affinity chromatography technology	Xu M (2003)	1
CTNNB1	30	RNF14	2	affinity chromatography technology	Wu B (2013)	1
CTNNB1	30	FHIT	0	affinity chromatography technology, pull down, imaging technique	Weiske J (2007), Weiske J (2007), Weiske J (2007)	3
NFATC1	12	NFATC2	1	affinity chromatography technology	Gabriel CH (2016)	1
RNF14	2	LEF1	3	affinity chromatography technology	Wu B (2013)	1
SMAD3	1	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian YC (2002), Dahle O (2010), Charbonney E (2011), Zhou B (2012)	4
DAZAP2	1	TCF7L2	12	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Lukas J (2009), Lukas J (2009), Lukas J (2009), Lukas J (2009)	4
LEF1	3	FHIT	0	affinity chromatography technology	Weiske J (2007)	1
SMAD1	0	SMAD4	9	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harada J (2003), Hanai J (1999), Lopez-Rovira T (2002), Kato Y (2002), Wang L (2011), Li L (2004), Hata A (1998), Barrios-Rodiles M (2005), Wu RY (1997), Wu RY (1997), Colland F (2004), Qiu T (2007), Yan X (2016), Zhou F (2017)	14
CTNNB1	30	HINT1	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Genovese G (2012), Genovese G (2012), Weiske J (2005)	3
NLK	1	CTNNB1	30	affinity chromatography technology	Ishitani T (2003)	1
NFATC2	1	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Garcia-Rodriguez C (1998), Garcia-Rodriguez C (1998), Gabriel CH (2016), Gabriel CH (2016)	4
SMAD3	1	SMAD1	0	affinity chromatography technology, two hybrid, two hybrid	Brown KA (2008), Wu RY (1997), Wu RY (1997)	3
LEF1	3	SMAD4	9	pull down	Labbe E (2000)	1
SMAD3	1	PITX2	1	affinity chromatography technology	Lamba P (2008)	1
LEF1	3	STAT5A	4	affinity chromatography technology, imaging technique	Gupta K (2014), Gupta K (2014)	2
NOTCH1	25	LEF1	3	pull down	Ross DA (2001)	1
ALYREF	0	LEF1	3	pull down	Bruhn L (1997)	1
TCF7L2	12	PRMT6	2	affinity chromatography technology	Huttlin EL (2017)	1
SMAD3	1	NOTCH1	25	pull down, affinity chromatography technology	Blokzijl A (2003), Blokzijl A (2003)	2
EP300	36	SMAD7	1	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Groenroos E (2002), Groenroos E (2002), Groenroos E (2002), Groenroos E (2002)	4
SMAD1	0	LEF1	3	affinity chromatography technology	Cui Q (2005)	1
SMAD3	1	ZBTB3	3	two hybrid	Ravasi T (2010)	1
LEF1	3	KMT5A	2	affinity chromatography technology, pull down, affinity chromatography technology	Li Z (2011), Li Z (2011), Li Z (2011)	3
SMAD1	0	HDAC1	4	affinity chromatography technology	Takeda M (2004)	1
DPYSL2	3	LEF1	3	two hybrid	Wang J (2011)	1
TLE1	6	CTNNB1	30	pull down	Levanon D (1998)	1
EGLN3	0	LEF1	3	affinity chromatography technology	Rodriguez J (2016)	1
EP300	36	SMAD2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Wotton D (1999), Pessah M (2001), Furumatsu T (2005), Wang J (2011), Suganuma T (2002)	5
RUVBL1	2	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bauer A (1998), Bauer A (1998), Bauer A (1998), Bauer A (1998), Sierra J (2006), Gomes NP (2006), Kim JH (2007), Kim JH (2007)	8
RUVBL1	2	LEF1	3	affinity chromatography technology	Bauer A (1998)	1
EGLN3	0	CTNNB1	30	affinity chromatography technology	Rodriguez J (2016)	1
PIAS4	5	LEF1	3	two hybrid, pull down, affinity chromatography technology	Sachdev S (2001), Sachdev S (2001), Sachdev S (2001)	3
SMAD3	1	SMAD2	5	affinity chromatography technology, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Nakao A (1997), Lebrun JJ (1999), Dumont E (2003), Brown KA (2008), Brown KA (2008), Wu RY (1997), Wu RY (1997), Tang Y (2003), Tang Y (2003), Wang J (2011), Huttlin EL (2015), Huttlin EL (2017)	12
LEF1	3	EP300	36	enzymatic study, affinity chromatography technology, pull down	Hecht A (2003), Hecht A (2003), Hecht A (2003)	3
TLE1	6	TLE2	4	pull down, pull down, two hybrid	Grbavec D (1998), Grbavec D (1998), Grbavec D (1998)	3
NFATC2	1	HDAC1	4	affinity chromatography technology	Gabriel CH (2016)	1
NFATC2	1	LEF1	3	affinity chromatography technology	Gabriel CH (2016)	1
SMAD2	5	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wotton D (1999), Wotton D (1999), Takeda M (2004), Lo RS (2001)	4
EP300	36	MITF	3	affinity chromatography technology	Price ER (1998)	1
SMAD2	5	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian YC (2002), Dahle O (2010), Xi Y (2013)	3
SMAD4	9	CTNNB1	30	affinity chromatography technology	Tian YC (2002)	1
CTNNB1	30	EP300	36	genetic interference, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, genetic interference, affinity chromatography technology	Kennell JA (2003), Sun Y (2000), Sun Y (2000), Sun Y (2000), Saegusa M (2005), Daniels DL (2002), Levy L (2004), Labalette C (2004), Lee YH (2006), Zhao Y (2016)	10
LEF1	3	SMAD2	5	pull down, affinity chromatography technology, affinity chromatography technology	Labbe E (2000), Labbe E (2000), Cui Q (2005)	3
SMAD4	9	HDAC1	4	affinity chromatography technology	Takeda M (2004)	1
EP300	36	STAT5A	4	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Pfitzner E (1998), Pfitzner E (1998), Pfitzner E (1998), Kotla S (2015)	4
PIAS4	5	SMAD2	5	affinity chromatography technology, two hybrid, affinity chromatography technology	Imoto S (2003), Long J (2003), Long J (2003)	3
SMAD3	1	SMAD4	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Seoane J (2004), Moren A (2003), Wu JW (2002), Nakao A (1997), Hanai J (1999), Lebrun JJ (1999), Poncelet AC (2001), Jablonska E (2010), Prunier C (2003), Kato Y (2002), Kaimori A (2010), Tang LY (2011), Tang LY (2011), Dupont S (2009), Dupont S (2009), Pardali K (2000), Kardassis D (2000), Xu L (2003), Fu G (2011), Chen W (2007), Kang JM (2012), Gao S (2009), Li H (2009), Li H (2009), Brown KA (2008), Brown KA (2008), Halder SK (2005), Barrios-Rodiles M (2005), Dai F (2007), Dai F (2007), Chacko BM (2004), Chacko BM (2004), Chacko BM (2004), Stroschein SL (1999), Stroschein SL (1999), Stroschein SL (1999), Wu RY (1997), Wu RY (1997), Wu RY (1997), Wu RY (1997), Tomita M (2004), Colland F (2004), Colland F (2004), Tang Y (2003), Ding L (2009), Fattet L (2013), Wang J (2011), Xue J (2014), Ali A (2013), Gao S (2009), Yamakawa N (2002), Yamakawa N (2002), Wang G (2005), Li X (2015), Zhou F (2014), Yang Y (2015), Yan X (2016), Yan X (2016), Wu Y (2017), Wu Y (2017)	60
STAT5A	4	NLK	1	imaging technique	Gupta K (2014)	1
MITF	3	HINT1	0	two hybrid, affinity chromatography technology	Genovese G (2012), Genovese G (2012)	2
NFATC1	12	LEF1	3	affinity chromatography technology	Gabriel CH (2016)	1
ALYREF	0	SMAD4	9	affinity chromatography technology	Cheng H (2006)	1
EP300	36	NOTCH1	25	affinity chromatography technology, enzymatic study, affinity chromatography technology, two hybrid	Hao L (2010), Popko-Scibor AE (2011), Popko-Scibor AE (2011), Popko-Scibor AE (2011)	4
EP300	36	SMAD1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pearson KL (1999), Nakashima K (1999), Nakashima K (1999), Jeon EJ (2006), Jun JH (2010), Weng Q (2012)	6
RNF138	0	HDAC1	4	affinity chromatography technology	Han D (2016)	1
RNF138	0	TCF7L2	12	enzymatic study, affinity chromatography technology	Yamada M (2006), Yamada M (2006)	2
LEF1	3	HINT1	0	affinity chromatography technology	Weiske J (2005)	1
SMAD7	1	TCF7L2	12	affinity chromatography technology	Edlund S (2005)	1
NOTCH1	25	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, pull down	Jin YH (2009), Jin YH (2009), Jin YH (2009)	3
E2F1	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nicolas E (2000), Zhou F (2008), Peche LY (2015), Peche LY (2015)	4
LEF1	3	RNF138	0	affinity chromatography technology, enzymatic study, affinity chromatography technology	Yamada M (2006), Yamada M (2006), Han D (2016)	3
STAT5A	4	NARF	2	imaging technique	Gupta K (2014)	1
PIAS4	5	HDAC1	4	pull down	Gross M (2004)	1
TLE2	4	LEF1	3	pull down	Daniels DL (2005)	1
MITF	3	LEF1	3	two hybrid, affinity chromatography technology, pull down, pull down	Yasumoto K (2002), Yasumoto K (2002), Yasumoto K (2002), Saito H (2002)	4
LEF1	3	NARF	2	affinity chromatography technology, affinity chromatography technology, imaging technique	Gupta K (2014), Gupta K (2014), Gupta K (2014)	3
EGLN3	0	RNF138	0	affinity chromatography technology	Rodriguez J (2016)	1
PITX2	1	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, imaging technique	Kioussi C (2002), Kioussi C (2002), Chen TC (2014)	3
NOTCH1	25	HDAC1	4	affinity chromatography technology, affinity chromatography technology	Yatim A (2012), Yatim A (2012)	2
PIAS4	5	SMAD4	9	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Imoto S (2003), Long J (2003), Long J (2003), Long J (2003), Lee PS (2003)	5
TLE1	6	LEF1	3	pull down, pull down, x-ray crystallography	Levanon D (1998), Daniels DL (2005), Daniels DL (2005)	3
LEF1	3	MYB	3	affinity chromatography technology	Zhou F (2011)	1
UBTF	8	TLE1	6	affinity chromatography technology	Ali SA (2010)	1
SMAD2	5	SMAD1	0	affinity chromatography technology, two hybrid, two hybrid, fluorescent resonance energy transfe	Brown KA (2008), Wu RY (1997), Wu RY (1997), Ivanov AA (2017)	4
EP300	36	NFATC1	12	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim JH (2011), Kawamura T (2004), Kawamura T (2004), Gabriel CH (2016), Gabriel CH (2016)	5
LEF1	3	UBTF	8	affinity chromatography technology	Grueneberg DA (2003)	1