Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
ORM1 5004 THALIDOMIDE CHEMBL468 binder DrugBank 8755512

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
ORM1 rs17650 AG + GG warfarin dosage yes ORM1 S carriers (G allele carriers) may require lower maintenance doses to achieve and maintain an optimal level of anticoagulation. This variant is evaluated along with CYP2C9 rs1057910 (*3) and VKORC1 rs7294. Genotypes AG + GG is associated with decreased dose of warfarin as compared to genotype AA. 23208322 1184483448