Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
NUMA1 rs10898815 GG calcium channel blockers efficacy yes Increased response as determined by a greater decrease in diastolic blood pressure but not systolic blood pressure. Please note; this gene is on the minus strand, and the alleles have been complemented from those reported in the article to give the alleles on the plus chromosome. Genotype GG is associated with increased response to calcium channel blockers in people with Hypertension as compared to genotype AA. 24192120 1183688944