Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications
NFKBIA	4792	ASPIRIN	CHEMBL25		DrugBank	10553090

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
NFKBIA	rs2145623	CC + CG	adalimumab	efficacy	yes	as measured by PASI75 at 3 months. Caution this is a C/G SNP and its is unclear which strand the genotypes were measured on, since gene is on minus strand have complemented here compared to in Table 2 of paper.	Genotypes CC + CG is associated with decreased response to adalimumab or infliximab in people with Psoriasis as compared to genotype GG.	29192552	1449155510
NFKBIA	rs2145623	CC	ustekinumab	efficacy	yes	as measured by PASI75 at 4 months and adjusted for weight and FDR. Caution this is C/G SNP in gene on minus strand, it appeared from looking at other minus strand genes that all variants in the paper were measured on plus strand so results are reported as stated as in the paper and not complemented.	Genotype CC is associated with decreased response to ustekinumab in people with Psoriasis as compared to genotypes CG + GG.	27977334	1448594422
NFKBIA	rs696	T	etanercept	efficacy	no	Patients received etanercept for at least 3 months. Patients were classified as responders if they achieved a Psoriasis Area and Severity Index improvement of at least 75% after 12 weeks.	Allele T is associated with response to etanercept in people with Psoriasis as compared to allele C.	27348478	1448254981