PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
MDM2	2	TBP	0	pull down, pull down	Leveillard T (1997), Thut CJ (1997)	2
MAP2K7	5	JUN	0	enzymatic study	Sundarrajan M (2003)	1
EP300	36	MAF	4	two hybrid, affinity chromatography technology, affinity chromatography technology	Chen Q (2002), Chen Q (2002), Chen Q (2002)	3
ATF3	0	ATF2	1	two hybrid, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Ravasi T (2010), Reinke AW (2013), Reinke AW (2013)	3
DNMT3L	2	DDIT3	1	pull down	Pacaud R (2014)	1
ATF2	1	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
EGLN3	0	POLR2C	0	affinity chromatography technology	Rodriguez J (2016)	1
ATF4	2	BFSP2	1	two hybrid	Rolland T (2014)	1
JUN	0	APP	1	pull down	Miyamoto-Sato E (2010)	1
BATF	0	ATF2	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ATF4	2	JUN	0	pull down, two hybrid, fluorescent resonance energy transfe, fluorescent resonance energy transfe, imaging technique	Hai T (1991), Bandyopadhyay S (2010), Reinke AW (2013), Reinke AW (2013), Chen TC (2014)	5
CEBPE	0	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
CREBBP	29	NFE2L2	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Katoh Y (2001), Katoh Y (2001), Katoh Y (2001), Liu GH (2008), Liu GH (2008), Sun Z (2009), Sun Z (2009), Sun Z (2009)	8
CEBPA	0	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
MOV10	6	CKAP4	0	affinity chromatography technology	Castello A (2012)	1
MDM2	2	KAT2B	2	pull down, affinity chromatography technology, genetic interference, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Jin Y (2002), Jin Y (2002), Jin Y (2002), Jin Y (2004), Jin Y (2004), Jung CR (2010), Morgan JE (2017)	7
CEBPE	0	JUN	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
TBP	0	FOS	0	pull down, affinity chromatography technology, affinity chromatography technology	Metz R (1994), Metz R (1994), Bossis G (2005)	3
ATF4	2	TBC1D25	3	affinity chromatography technology	Huttlin EL (2017)	1
FOS	0	MAF	4	affinity chromatography technology, fluorescent resonance energy transfe	Annunziata CM (2011), Reinke AW (2013)	2
ATF4	2	GOLGA8F	0	two hybrid	Rolland T (2014)	1
BATF	0	CEBPG	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	JUNB	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
CREBBP	29	FOS	0	pull down, affinity chromatography technology, two hybrid	Fan S (2002), Bossis G (2005), Patel D (1999)	3
ATF4	2	HK3	3	two hybrid	Wang J (2011)	1
NFE2L2	1	NFE2	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
JUNB	0	EP300	36	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Narayanan K (2004), Narayanan K (2004), Narayanan K (2004), Wang CC (2007), Wang WM (2011)	5
JUN	0	TBP	0	pull down, pull down	Franklin CC (1995), Franklin CC (1995)	2
CEBPA	0	MAF	4	affinity chromatography technology	Zada AA (2006)	1
ATF4	2	ZNF226	1	two hybrid	Ravasi T (2010)	1
MAFB	1	MAF	4	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
BATF	0	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
FOSL1	0	LDOC1	0	two hybrid, two hybrid	Rual JF (2005), Venkatesan K (2009)	2
TBP	0	CREBBP	29	affinity chromatography technology	Dallas PB (1997)	1
JUN	0	BATF	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
NXF1	0	CKAP4	0	affinity chromatography technology	Castello A (2012)	1
ATF4	2	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
DNMT3L	2	ATF2	1	pull down	Pacaud R (2014)	1
JUNB	0	ATF2	1	affinity chromatography technology	Huttlin EL (2017)	1
CEBPE	0	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, pull down	Reinke AW (2013), Reinke AW (2013), Reddy KV (2003)	3
FOSL1	0	EP300	36	affinity chromatography technology, enzymatic study	Crish JF (2008), Wang WM (2011)	2
ATF4	2	390535	0	two hybrid	Rolland T (2014)	1
CREBBP	29	GTF2B	1	pull down, pull down	Tini M (2002), Fan S (2002)	2
ATF4	2	TGM2	2	two hybrid	Wang J (2011)	1
ATF4	2	GCC1	1	two hybrid	Rolland T (2014)	1
ATF2	1	FOS	0	pull down, fluorescent resonance energy transfe, fluorescent resonance energy transfe, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hai T (1991), Reinke AW (2013), Reinke AW (2013), Miyamoto-Sato E (2010), Rolland T (2014), Huttlin EL (2015), Li X (2015), Huttlin EL (2017)	8
MOV10	6	ATF4	2	affinity chromatography technology	Castello A (2012)	1
CEBPE	0	DDIT3	1	two hybrid, pull down	Chih DY (2004), Chih DY (2004)	2
JUNB	0	JUN	0	affinity chromatography technology	Huttlin EL (2017)	1
BATF3	0	JUNB	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology	Reinke AW (2013), Reinke AW (2013), Huttlin EL (2017)	3
NXF1	0	APH1A	2	affinity chromatography technology	Castello A (2012)	1
APH1A	2	ATF4	2	two hybrid	Wang J (2011)	1
HAUS7	0	ATF4	2	two hybrid	Xin X (2009)	1
DNMT3L	2	ATF4	2	pull down	Pacaud R (2014)	1
ATF2	1	CEBPA	0	two hybrid	Hong S (2004)	1
MDM2	2	RPS6	1	affinity chromatography technology	Bursac S (2012)	1
FOS	0	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ZNF212	1	ATF3	0	two hybrid	Gao J (2008)	1
BATF2	0	DDIT3	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ATF4	2	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ATF4	2	GOLGA1	0	two hybrid	Rolland T (2014)	1
EP300	36	KAT2B	2	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Kim JH (2011), Lee M (2010), Santos-Rosa H (2003), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996), Mizuguchi Y (2012)	8
FBXW11	2	PTCD3	3	affinity chromatography technology	Kim TY (2014)	1
ATF4	2	GTF2B	1	pull down	Liang G (1997)	1
NEK6	2	ATF4	2	two hybrid, pull down, enzymatic study	Vaz Meirelles G (2010), Vaz Meirelles G (2010), Vaz Meirelles G (2010)	3
GTF2B	1	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
NFE2	0	BTRC	1	two hybrid	Rolland T (2014)	1
GTF2B	1	NXF1	0	affinity chromatography technology	Yu L (1995)	1
CREBBP	29	MDM2	2	affinity chromatography technology, enzymatic study, affinity chromatography technology	Inoue Y (2011), Wang X (2004), Sanchez M (2012)	3
SHMT2	3	ATF4	2	affinity chromatography technology	Castello A (2012)	1
GABBR1	0	DDIT3	1	affinity chromatography technology, imaging technique	Sauter K (2005), Sauter K (2005)	2
ATF4	2	MPZL2	0	two hybrid	Wang J (2011)	1
GABBR2	15	ATF4	2	affinity chromatography technology	White JH (2000)	1
NLGN3	3	ATF4	2	two hybrid	Shen C (2015)	1
FOS	0	APP	1	pull down	Miyamoto-Sato E (2010)	1
BTRC	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down	Inuzuka H (2010), Inuzuka H (2010), Inuzuka H (2010)	3
BATF	0	ATF3	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DNMT3L	2	JUN	0	pull down	Pacaud R (2014)	1
CEBPE	0	CEBPG	1	two hybrid, pull down, fluorescent resonance energy transfe	Chih DY (2004), Chih DY (2004), Reinke AW (2013)	3
ATF2	1	APP	1	pull down	Olah J (2011)	1
MOV10	6	BTRC	1	affinity chromatography technology	Castello A (2012)	1
TRIB3	0	APP	1	pull down	Olah J (2011)	1
DDIT3	1	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
CEBPG	1	FOS	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
TBP	0	EP300	36	affinity chromatography technology	Dallas PB (1997)	1
FOSL1	0	TRIM24	1	two hybrid	Ravasi T (2010)	1
FBXW11	2	NFKBIA	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Suzuki H (2000), Tan P (1999), Suzuki H (1999), Suzuki H (1999), Herter JR (2002), Chong RA (2014), Herter JR (2002), Huttlin EL (2015), Huttlin EL (2017), Gazdoiu S (2007)	10
SHMT2	3	CREB3	1	affinity chromatography technology, two hybrid	Castello A (2012), Yu H (2011)	2
FOSL1	0	JUN	0	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Pognonec P (1997), Pognonec P (1997), Kumar NV (2001), Kumar NV (2001), Reinke AW (2013), Reinke AW (2013)	6
DDIT3	1	ATF3	0	affinity chromatography technology, pull down, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Chen BP (1996), Chen BP (1996), Reinke AW (2013), Reinke AW (2013)	4
NXF1	0	CREBZF	0	affinity chromatography technology	Castello A (2012)	1
ATF3	0	FOS	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ATF3	0	CREBBP	29	affinity chromatography technology, pull down	Kim HB (2010), Kim HB (2010)	2
CEBPG	1	ATF2	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
CEBPG	1	ATF4	2	fluorescent resonance energy transfe, two hybrid	Reinke AW (2013), Rolland T (2014)	2
ATF3	0	CEBPE	0	imaging technique, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Lopez AB (2007), Reinke AW (2013), Reinke AW (2013)	3
FBXW11	2	NFE2L2	1	affinity chromatography technology, affinity chromatography technology	Kim TY (2014), Low TY (2014)	2
ATF4	2	ZNF212	1	two hybrid	Gao J (2008)	1
DDIT3	1	CREBBP	29	affinity chromatography technology	Park SH (2010)	1
POLR2C	0	GTF2F2	0	affinity chromatography technology	Ayguen O (2008)	1
FBXW11	2	SHMT2	3	affinity chromatography technology	Low TY (2014)	1
FBXW11	2	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Suzuki H (2000), Suzuki H (2000), Sowa ME (2009), Sowa ME (2009), Coyaud E (2015), Coyaud E (2015), Coyaud E (2015), Huttlin EL (2017), Liu X (2017)	9
MOV10	6	CREB3	1	affinity chromatography technology	Castello A (2012)	1
EGLN3	0	EGLN2	4	affinity chromatography technology, affinity chromatography technology	Nakayama K (2007), Nakayama K (2007)	2
EP300	36	FOS	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Wang WM (2011), Pekarsky Y (2008), Wang C (2001)	3
JUNB	0	FOSL1	0	two hybrid, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Rual JF (2005), Reinke AW (2013), Reinke AW (2013)	3
CEBPE	0	LDOC1	0	two hybrid, pull down	Chih DY (2004), Chih DY (2004)	2
GABBR1	0	ATF4	2	two hybrid, affinity chromatography technology	White JH (2000), White JH (2000)	2
ATF4	2	MDM2	2	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Wang J (2011), Riscal R (2016), Riscal R (2016), Riscal R (2016)	4
CEBPA	0	JUN	0	affinity chromatography technology	Zada AA (2006)	1
SHMT2	3	APP	1	pull down	Olah J (2011)	1
JUNB	0	BATF	0	two hybrid, fluorescent resonance energy transfe, fluorescent resonance energy transfe, two hybrid, two hybrid	Wang X (1996), Reinke AW (2013), Reinke AW (2013), Rolland T (2014), Yu H (2011)	5
CREB3	1	APH1A	2	two hybrid	Yu H (2011)	1
DDIT3	1	ATF2	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
ATF3	0	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
DNMT3L	2	JUNB	0	pull down	Pacaud R (2014)	1
DDIT3	1	TRIB3	0	affinity chromatography technology, pull down	Ohoka N (2007), Ohoka N (2007)	2
FOS	0	JUNB	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Reinke AW (2013), Reinke AW (2013), Rolland T (2014), Huttlin EL (2015), Hein MY (2015), Li X (2015), Huttlin EL (2017)	7
BATF3	0	BATF	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ATF4	2	CKAP4	0	two hybrid	Wang J (2011)	1
MAF	4	NFE2L2	1	affinity chromatography technology	Liu K (2015)	1
ATF4	2	TBP	0	pull down	Liang G (1997)	1
DDIT3	1	CEBPA	0	affinity chromatography technology, two hybrid, affinity chromatography technology	Marwarha G (2016), Marwarha G (2016), Marwarha G (2016)	3
MAF	4	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
ATF3	0	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
NXF1	0	ATF4	2	affinity chromatography technology	Castello A (2012)	1
ATF3	0	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
BATF3	0	ATF3	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	BATF	0	two hybrid, fluorescent resonance energy transfe, fluorescent resonance energy transfe, two hybrid	Rual JF (2005), Reinke AW (2013), Reinke AW (2013), DeGrado-Warren J (2008)	4
ATF4	2	ATF4	2	fluorescent resonance energy transfe	Reinke AW (2013)	1
DDIT3	1	FOS	0	pull down, affinity chromatography technology, fluorescent resonance energy transfe	Ubeda M (1999), Ubeda M (1999), Reinke AW (2013)	3
EIF2A	0	APP	1	pull down	Olah J (2011)	1
DNMT3L	2	FOS	0	pull down	Pacaud R (2014)	1
CREB3	1	ATF4	2	fluorescent resonance energy transfe	Reinke AW (2013)	1
BATF2	0	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
MDM2	2	JUN	0	pull down	Miyamoto-Sato E (2010)	1
EP300	36	BTRC	1	affinity chromatography technology, affinity chromatography technology	Kimbrel EA (2009), Kimbrel EA (2009)	2
JUN	0	GTF2B	1	pull down, pull down	Franklin CC (1995), Franklin CC (1995)	2
ATF4	2	FOS	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, imaging technique	Reinke AW (2013), Reinke AW (2013), Chen TC (2014)	3
DDIT3	1	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
KAT2B	2	JUN	0	affinity chromatography technology	Tsai LN (2008)	1
EIF2A	0	RPS6	1	biochemical	Singh CR (2011)	1
GCC1	1	APP	1	pull down	Olah J (2011)	1
CEBPE	0	GTF2A1L	0	two hybrid	Ravasi T (2010)	1
JUN	0	NFE2L2	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Venugopal R (1998), Venugopal R (1998), Levy S (2010), Lee AC (2010)	4
FBXW11	2	ATF4	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Frank CL (2010), Gao D (2011), Kim TY (2014), Low TY (2014)	4
JUN	0	GTF2F2	0	pull down	Martin ML (1996)	1
ATF4	2	KAT2B	2	pull down	Cherasse Y (2007)	1
GABBR1	0	GABBR2	15	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	White JH (1998), White JH (1998), White JH (1998), Lahaie N (2016)	4
FOS	0	GTF2F2	0	pull down	Martin ML (1996)	1
CCDC106	1	ATF4	2	two hybrid, two hybrid	Stelzl U (2005), Rolland T (2014)	2
CEBPA	0	CEBPG	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
CREBBP	29	FOSL1	0	affinity chromatography technology	Tran NQ (2004)	1
FOS	0	JUN	0	pull down, two hybrid, pull down, x-ray crystallography, two hybrid, pull down, two hybrid, two hybrid, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, fluorescent resonance energy transfe, pull down, pull down, imaging technique, pull down, affinity chromatography technology, pull down, pull down, fluorescent resonance energy transfe, pull down, pull down, affinity chromatography technology, biochemical, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ito T (2001), Pognonec P (1997), Pognonec P (1997), Glover JN (1995), Yang X (1999), Nomura N (1993), Finkel T (1993), Finkel T (1993), Venugopal R (1998), Kumar NV (2001), Dumin E (2006), Bandyopadhyay S (2010), Asim M (2010), Asim M (2010), Srivastav RK (2011), Bossis G (2005), Bossis G (2005), Gupta K (2000), Bachmann M (2004), Reinke AW (2013), Miyagi M (2005), Subbaramaiah K (2007), Jang M (2012), Yamaguchi K (2005), Varjosalo M (2013), Miyamoto-Sato E (2010), Miyamoto-Sato E (2010), Varjosalo M (2013), Tang HY (2006), Marden NY (2005), Adler J (2010), Adler J (2010), Adler J (2010), Billiet L (2008), Huttlin EL (2015), Hein MY (2015), Li X (2015), Li X (2015), Huttlin EL (2017)	39
DDIT3	1	GABBR2	15	two hybrid, affinity chromatography technology, imaging technique	Sauter K (2005), Sauter K (2005), Sauter K (2005)	3
MDM2	2	ATF3	0	pull down, affinity chromatography technology, pull down, enzymatic study	Yan C (2005), Mo P (2010), Mo P (2010), Mo P (2010)	4
CEBPG	1	JUN	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
ATF4	2	POLR2C	0	two hybrid, affinity chromatography technology, pull down	De Angelis R (2003), De Angelis R (2003), De Angelis R (2003)	3
GTF2B	1	TBP	0	biochemical, pull down, x-ray crystallography, pull down, x-ray crystallography, x-ray crystallography, pull down	Scully R (1997), Scully R (1997), Bushnell DA (2004), Friedman MJ (2007), Tsai FT (2000), Bagby S (1995), Lin Y (1997)	7
NXF1	0	BTRC	1	affinity chromatography technology	Castello A (2012)	1
CREB3	1	NFE2L2	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
BATF3	0	ATF2	1	fluorescent resonance energy transfe, affinity chromatography technology	Reinke AW (2013), Huttlin EL (2017)	2
CEBPG	1	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
BATF	0	CEBPE	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
JUN	0	ATF2	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, fluorescent resonance energy transfe, fluorescent resonance energy transfe, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Newell CL (1994), Newell CL (1994), Kara CJ (1990), Hai T (1991), Fuchs SY (1999), Reinke AW (2013), Reinke AW (2013), Miyamoto-Sato E (2010), Hayakawa J (2004), Hein MY (2015), Li X (2015), Huttlin EL (2017)	12
BATF3	0	CEBPA	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ATF4	2	GPS2	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
CEBPA	0	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
HAUS7	0	CKAP4	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAFB	1	ATF4	2	fluorescent resonance energy transfe	Reinke AW (2013)	1
ATF3	0	JUNB	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology	Reinke AW (2013), Reinke AW (2013), Huttlin EL (2017)	3
ATF4	2	PTCD3	3	two hybrid	Rual JF (2005)	1
MAF	4	ATF4	2	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DDIT3	1	CREB3	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
MAFB	1	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
EP300	36	GTF2B	1	pull down	Felzien LK (1999)	1
CREBZF	0	ATF4	2	fluorescent resonance energy transfe	Reinke AW (2013)	1
EGLN2	4	ATF4	2	two hybrid, affinity chromatography technology	Hiwatashi Y (2011), Hiwatashi Y (2011)	2
NFKBIA	0	POLR2C	0	two hybrid	Wang J (2011)	1
ZNF212	1	NFKBIA	0	two hybrid	Gao J (2008)	1
BATF2	0	ATF4	2	fluorescent resonance energy transfe	Reinke AW (2013)	1
DDIT3	1	BATF3	0	fluorescent resonance energy transfe, two hybrid	Reinke AW (2013), Rolland T (2014)	2
MAF	4	CREBBP	29	affinity chromatography technology, affinity chromatography technology	Chen Q (2002), Chen Q (2002)	2
EP300	36	NFKBIA	0	affinity chromatography technology	Shin DH (2009)	1
MOV10	6	APH1A	2	affinity chromatography technology	Castello A (2012)	1
EP300	36	DDIT3	1	affinity chromatography technology, affinity chromatography technology, pull down	Jeong K (2014), Ohoka N (2007), Ohoka N (2007)	3
BATF2	0	CEBPG	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ATF4	2	APP	1	pull down	Olah J (2011)	1
CREBBP	29	JUNB	0	affinity chromatography technology	Tran NQ (2004)	1
ATF4	2	EP300	36	affinity chromatography technology, pull down, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology	Lassot I (2005), Lassot I (2005), Lassot I (2005), Deng WG (2004), Deng WG (2004), Ohoka N (2007), Deng WG (2003)	7
BATF3	0	CEBPE	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
NFE2L2	1	ATF4	2	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
EIF2A	0	NXF1	0	affinity chromatography technology	Pfeifer I (2008)	1
CREBBP	29	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Dohda T (2004), Dohda T (2004)	3
GPS2	0	EP300	36	affinity chromatography technology, affinity chromatography technology, pull down	Peng YC (2000), Peng YC (2000), Peng YC (2000)	3
ATF3	0	JUN	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Pearson AG (2003), Chen BP (1996), Hai T (1991), Filen S (2010), Reinke AW (2013), Reinke AW (2013), Hein MY (2015), Li X (2015)	8
CEBPE	0	FOS	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
DDIT3	1	JUN	0	pull down, affinity chromatography technology, fluorescent resonance energy transfe	Ubeda M (1999), Ubeda M (1999), Reinke AW (2013)	3
BATF	0	ATF4	2	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ATF4	2	GTF2A1L	0	two hybrid	Ravasi T (2010)	1
SHMT2	3	NDC80	4	affinity chromatography technology	Castello A (2012)	1
ATF2	1	FOSL1	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
ATF4	2	FOSL1	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
MAFB	1	FOS	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ATF4	2	NDC80	4	two hybrid	Rolland T (2014)	1
NFE2L2	1	TRIM24	1	two hybrid	Ravasi T (2010)	1
DISC1	6	ATF4	2	two hybrid	Morris JA (2003)	1
NFKBIA	0	ATF4	2	two hybrid	Gao J (2008)	1
CCDC106	1	APP	1	pull down	Olah J (2011)	1
MAFB	1	KAT2B	2	affinity chromatography technology	Scoville DW (2015)	1
EGLN3	0	JUN	0	affinity chromatography technology	Rodriguez J (2016)	1
BATF2	0	JUN	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
DNMT3L	2	ATF3	0	pull down	Pacaud R (2014)	1
ATF2	1	SHMT2	3	affinity chromatography technology	Lau E (2012)	1
ATF4	2	DDIT3	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe, two hybrid	Reinke AW (2013), Reinke AW (2013), DeGrado-Warren J (2008)	3
EGLN3	0	GPS2	0	affinity chromatography technology	Rodriguez J (2016)	1
BATF3	0	ATF4	2	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ATF4	2	TREX2	0	two hybrid	Rual JF (2005)	1
FBXW11	2	APP	1	affinity chromatography technology	Low TY (2014)	1
ATF4	2	JUNB	0	two hybrid	Wang J (2011)	1
CEBPG	1	CREB3	1	fluorescent resonance energy transfe	Reinke AW (2013)	1
FBXW11	2	MDM2	2	affinity chromatography technology	Inuzuka H (2010)	1
NXF1	0	LDOC1	0	two hybrid	Rolland T (2014)	1
ATF4	2	LDOC1	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
ATF4	2	LMNB1	1	two hybrid	Wang J (2011)	1
FBXW11	2	MOV10	6	affinity chromatography technology, affinity chromatography technology	Low TY (2014), Huttlin EL (2017)	2
BTRC	1	NFE2L2	1	affinity chromatography technology, bioid	Loveless TB (2015), Coyaud E (2015)	2
ATF4	2	CREBBP	29	pull down, affinity chromatography technology, imaging technique	Liang G (1997), Venza I (2001), Chen TC (2014)	3
CREBBP	29	KAT2B	2	pull down, biochemical, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Tini M (2002), Cho H (1998), Cho H (1998), Cho H (1998), Korzus E (1998), Korzus E (1998), Korzus E (1998), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996)	10
EGLN3	0	NDC80	4	affinity chromatography technology	Rodriguez J (2016)	1
ATF3	0	CEBPG	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
ASB7	1	ATF4	2	two hybrid	Wang J (2011)	1
ATF4	2	EIF2A	0	affinity chromatography technology	Gomez E (2004)	1
EGLN3	0	NFKBIA	0	affinity chromatography technology	Rodriguez J (2016)	1
TGM2	2	APP	1	pull down	Olah J (2011)	1
CREBBP	29	ATF2	1	pull down, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Sano Y (1998), Sano Y (1998), Sano Y (1998), Sano Y (1998), Deb S (2006), Merika M (1998), Johnson J (2007), Venza I (2001)	8
TBP	0	GTF2F2	0	pull down	Tang H (1996)	1
FOS	0	SRA1	0	far western blotting	Chooniedass-Kothari S (2010)	1
BATF3	0	CEBPG	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
NXF1	0	NDC80	4	affinity chromatography technology	Castello A (2012)	1
ATF4	2	RPS6	1	two hybrid	Wang J (2011)	1
CEBPG	1	DDIT3	1	two hybrid, affinity chromatography technology, two hybrid	Rual JF (2005), Hattori T (2003), Rolland T (2014)	3
BATF2	0	JUNB	0	fluorescent resonance energy transfe, fluorescent resonance energy transfe, two hybrid	Reinke AW (2013), Reinke AW (2013), Wang J (2011)	3
KAT2B	2	NFE2	0	enzymatic study	Patel JH (2004)	1
ATF4	2	TTR	0	two hybrid	Rual JF (2005)	1
MDM2	2	APP	1	pull down	Miyamoto-Sato E (2010)	1
POLR2C	0	GTF2B	1	affinity chromatography technology	Ayguen O (2008)	1
ATF4	2	ATF2	1	fluorescent resonance energy transfe, fluorescent resonance energy transfe	Reinke AW (2013), Reinke AW (2013)	2
CREB3	1	ATF3	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
BTRC	1	ATF4	2	affinity chromatography technology, two hybrid, affinity chromatography technology, x-ray crystallography, unspecified method, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid	Lassot I (2005), Lassot I (2001), Lassot I (2001), Evrard-Todeschi N (2008), Pons J (2008), Wang J (2011), Rolland T (2014), Loveless TB (2015), Loveless TB (2015), Yu H (2011)	10
NFKBIA	0	TGM2	2	affinity chromatography technology	Kumar S (2012)	1
ATF4	2	SNAP29	1	two hybrid	Wang J (2011)	1
ATF4	2	CEBPE	0	imaging technique, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Lopez AB (2007), Reinke AW (2013), Reinke AW (2013)	3
NFE2	0	ATF4	2	fluorescent resonance energy transfe	Reinke AW (2013)	1
NFE2	0	CREBBP	29	pull down, affinity chromatography technology, enzymatic study	Hung HL (2001), Hung HL (2001), Hung HL (2001)	3
EP300	36	JUN	0	pull down, biochemical, x-ray crystallography, affinity chromatography technology, pull down, enzymatic study, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Campbell KM (2002), Campbell KM (2002), Campbell KM (2002), Subbaramaiah K (2002), Duyndam MC (1999), Wang WM (2011), Deng WG (2004), Deng WG (2004), Cheng SE (2011), Cheng SE (2011), Kim BK (2014), Vries RG (2001), Deng WG (2003), Liu L (2017), Liu L (2017)	15
DNMT3L	2	FOSL1	0	pull down	Pacaud R (2014)	1
ATF4	2	GTF2F2	0	pull down	Liang G (1997)	1
JUN	0	CREB3	1	pull down	Miyamoto-Sato E (2010)	1
ATF4	2	TRIM24	1	two hybrid	Ravasi T (2010)	1
ATF4	2	ATF3	0	affinity chromatography technology, fluorescent resonance energy transfe, fluorescent resonance energy transfe	Wang Q (2009), Reinke AW (2013), Reinke AW (2013)	3
MOV10	6	CREBZF	0	affinity chromatography technology	Castello A (2012)	1
EGLN3	0	HAUS7	0	affinity chromatography technology	Rodriguez J (2016)	1
CREBBP	29	JUN	0	pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, far western blotting	Sano Y (1998), Sano Y (1998), Merika M (1998), Duyndam MC (1999), Johnson J (2007), Yamaguchi K (2005), Tsai LN (2008), Arias J (1994)	8
EP300	36	ATF2	1	biochemical	Duyndam MC (1999)	1
BTRC	1	NFKBIA	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, enzymatic study, enzymatic study, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, bioid, enzymatic study, protein complementation assay	Suzuki H (2000), Spencer E (1999), Spencer E (1999), Spencer E (1999), Suzuki H (1999), Suzuki H (1999), Kroll M (1999), Kroll M (1999), Yaron A (1998), Choi YS (2010), Banerjee S (2010), Banerjee S (2010), Banerjee S (2010), Da Silva-Ferrada E (2011), Tsuchiya Y (2010), Tsuchiya Y (2010), Keutgens A (2010), Winston JT (1999), Winston JT (1999), Winston JT (1999), Winston JT (1999), Surjit M (2012), Busino L (2012), Evrard-Todeschi N (2008), Furukawa M (2000), Kovacev J (2014), Chong RA (2014), Chong RA (2014), Shi M (2014), Shirane M (1999), Read MA (2000), Tan M (2010), Coyaud E (2015), Coyaud E (2015), Wu K (2016), Villalobos V (2010)	36
ATF4	2	MAP2K7	5	two hybrid	Wang J (2011)	1
EP300	36	MDM2	2	pull down, affinity chromatography technology, biochemical, pull down, pull down, enzymatic study, affinity chromatography technology, biochemical, enzymatic study	Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Matt T (2004), Wang X (2004), Gillotin S (2010), Kobet E (2000), Nihira NT (2017)	9
CEBPE	0	BATF2	0	fluorescent resonance energy transfe	Reinke AW (2013)	1
TBP	0	GTF2A1L	0	pull down	Upadhyaya AB (2002)	1
EGLN3	0	ATF4	2	two hybrid, affinity chromatography technology, two hybrid	Koeditz J (2007), Koeditz J (2007), Hiwatashi Y (2011)	3
EGLN3	0	CREBBP	29	affinity chromatography technology	Rodriguez J (2016)	1
BATF3	0	JUN	0	pull down, fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Iacobelli M (2000), Reinke AW (2013), Reinke AW (2013), Li X (2015), Huttlin EL (2017)	5
GTF2B	1	GTF2F2	0	pull down, pull down, biochemical	Fang SM (1996), Elsby LM (2006), Wan C (2015)	3
ATF4	2	REPS1	2	two hybrid	Wang J (2011)	1
TRIB3	0	ATF4	2	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid	Bowers AJ (2003), Bowers AJ (2003), Zhou Y (2008), Zhou Y (2008), Zhou Y (2008), Rolland T (2014)	6