PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
WDR5	2	KAT2A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang YL (2008), Huttlin EL (2015), Wang YL (2008), Huttlin EL (2017)	4
EP300	36	MAF	4	two hybrid, affinity chromatography technology, affinity chromatography technology	Chen Q (2002), Chen Q (2002), Chen Q (2002)	3
CUL4A	2	RPL4	4	affinity chromatography technology	Bennett EJ (2010)	1
UBE2I	0	EP300	36	enzymatic study, affinity chromatography technology	Girdwood D (2003), Bian XL (2017)	2
SUMO2	0	MYB	3	pull down	Saether T (2011)	1
HSPA8	4	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Du C (2017), Du C (2017)	3
KAT5	1	MYB	3	affinity chromatography technology, affinity chromatography technology	Zhao H (2012), Zhao H (2012)	2
FBXW7	2	NCOR1	9	genetic interference	Bailey ML (2015)	1
MYB	3	SKI	3	pull down, affinity chromatography technology, pull down	Nomura T (2004), Nomura T (2004), Nomura T (2004)	3
SMARCA2	17	SIN3A	13	biochemical, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Sif S (2001), Sif S (2001), Pal S (2003), Pal S (2003), Nakamura T (2002), Nakamura T (2002), Kemper JK (2004), Kemper JK (2004), Wan C (2015)	9
TRIM28	1	CEBPB	2	affinity chromatography technology, pull down	Chang CJ (1998), Chang CJ (1998)	2
GATA3	2	FBXW7	2	pull down, affinity chromatography technology	Kitagawa K (2014), Kitagawa K (2014)	2
TRIM28	1	MYB	3	pull down, pull down, affinity chromatography technology	Nomura T (2004), Nomura T (2004), Nomura T (2004)	3
UBE2I	0	TRAF6	0	enzymatic study, enzymatic study	Li Y (2013), Pham LV (2008)	2
EP300	36	PIAS1	4	pull down, affinity chromatography technology	Ledsaak M (2016), Ledsaak M (2016)	2
NCOR1	9	UBE2I	0	pull down, affinity chromatography technology	Tiefenbach J (2006), Tiefenbach J (2006)	2
MYB	3	PIAS1	4	two hybrid, pull down, pull down	Alm-Kristiansen AH (2011), Ledsaak M (2016), Ledsaak M (2016)	3
SUMO1	0	HIPK2	0	two hybrid, imaging technique, pull down	Lee BH (2003), de la Vega L (2011), de la Vega L (2011)	3
SMARCA2	17	MYB	3	pull down	Kowenz-Leutz E (1999)	1
TRAF6	0	DDB1	6	affinity chromatography technology	Antonioli M (2014)	1
SP100	4	SUMO2	0	two hybrid, two hybrid, pull down	Wang J (2011), Hecker CM (2006), Hecker CM (2006)	3
CREBBP	29	MYB	3	x-ray crystallography, pull down, genetic interference, affinity chromatography technology, pull down, pull down, enzymatic study, pull down, x-ray crystallography, pull down	Zor T (2002), Zor T (2002), Bessa M (2001), Kurahashi T (2005), Kurahashi T (2005), Sano Y (2001), Sano Y (2001), Nomura T (2004), Yang F (2006), Giri R (2013)	10
EP300	36	PARP1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Messner S (2009), Hassa PO (2005), Hassa PO (2005), Hassa PO (2005), Hassa PO (2008), Hassa PO (2008), Hassa PO (2003), Hassa PO (2003), Hassa PO (2003), Kim BK (2014), Kim BK (2014)	11
RBX1	2	MYB	3	pull down	Kanei-Ishii C (2008)	1
TRAF6	0	MYB	3	affinity chromatography technology, affinity chromatography technology	Pham LV (2008), Pham LV (2008)	2
MYB	3	KAT2B	2	imaging technique	Jin W (2011)	1
TRIM28	1	SIN3A	13	pull down	Nomura T (2004)	1
NCOR1	9	SMARCA2	17	biochemical	Havugimana PC (2012)	1
MYB	3	CUL4A	2	affinity chromatography technology	Kanei-Ishii C (2012)	1
PAX5	7	KAT2B	2	affinity chromatography technology	Perearnau A (2017)	1
NCOR1	9	SIN3A	13	pull down, affinity chromatography technology	Khan MM (2001), Farhana L (2007)	2
PML	7	CREBBP	29	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Matsuzaki K (2003), Matsuzaki K (2003), Matsuzaki K (2003), Doucas V (1999), Doucas V (1999), Zhong S (1999), Chen Y (2015)	7
CUL4A	2	RBBP5	3	affinity chromatography technology	Higa LA (2006)	1
ASH2L	2	MEN1	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yokoyama A (2004), MacConaill LE (2006), Hughes CM (2004), Hughes CM (2004), Hughes CM (2004)	5
ZMYND11	10	SMARCA2	17	affinity chromatography technology	Velasco G (2006)	1
UBE2I	0	SKI	3	pull down, affinity chromatography technology	Ding B (2012), Ding B (2012)	2
PARP1	3	UBE2I	0	two hybrid, affinity chromatography technology, pull down, enzymatic study, enzymatic study, pull down, enzymatic study	Masson M (1997), Masson M (1997), Masson M (1997), Zilio N (2013), Matafora V (2009), Zilio N (2013), Gocke CB (2005)	7
FBXW7	2	RBX1	2	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Busino L (2012), Matsumoto A (2011), Strohmaier H (2001), Ye M (2017)	4
MYB	3	WDR5	2	affinity chromatography technology	Jin S (2010)	1
CREBBP	29	NLK	1	affinity chromatography technology, enzymatic study	Kurahashi T (2005), Yasuda J (2004)	2
MAF	4	PML	7	imaging technique	Leavenworth JW (2009)	1
HLF	0	MYB	3	two hybrid	Ravasi T (2010)	1
PML	7	RBX1	2	affinity chromatography technology, enzymatic study	Shima Y (2008), Yuan WC (2011)	2
SUMO2	0	UBE2I	0	affinity chromatography technology, pull down, two hybrid, two hybrid, pull down, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, biochemical, affinity chromatography technology, affinity chromatography technology	Li T (2006), Knipscheer P (2007), Boutell C (2011), Hecker CM (2006), Hecker CM (2006), Zilio N (2013), Tatham MH (2001), Knipscheer P (2007), Ullmann R (2012), Matic I (2008), Xu Y (2014), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	14
HIPK2	0	SP100	4	affinity chromatography technology	Moeller A (2003)	1
CHD3	19	SUMO1	0	two hybrid, pull down	Minty A (2000), Goodarzi AA (2011)	2
NLK	1	MYB	3	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study	Kurahashi T (2005), Kurahashi T (2005), Kurahashi T (2005), Kanei-Ishii C (2004), Kanei-Ishii C (2004)	5
MYB	3	CEBPE	0	pull down	Verbeek W (1999)	1
STAT5A	4	MYB	3	affinity chromatography technology	Fang F (2009)	1
ASH2L	2	EP300	36	affinity chromatography technology, pull down, affinity chromatography technology	Tang Z (2013), Tang Z (2013), Tang Z (2013)	3
KAT5	1	SUMO1	0	affinity chromatography technology	Cheng Z (2008)	1
EP300	36	KAT2B	2	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Kim JH (2011), Lee M (2010), Santos-Rosa H (2003), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996), Mizuguchi Y (2012)	8
SP100	4	SUMO1	0	two hybrid, two hybrid, pull down, two hybrid	Rual JF (2005), Hecker CM (2006), Hecker CM (2006), Rolland T (2014)	4
TRIM28	1	SKI	3	pull down	Nomura T (2004)	1
PML	7	MYB	3	affinity chromatography technology, pull down	Dahle O (2004), Dahle O (2004)	2
SKI	3	RPL4	4	affinity chromatography technology	Rashidian J (2015)	1
TRIM28	1	CREBBP	29	affinity chromatography technology	Seki Y (2010)	1
CEBPB	2	EP300	36	genetic interference, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, imaging technique, affinity chromatography technology	Mink S (1997), Mink S (1997), Mink S (1997), Mink S (1997), Mink S (1997), Deng WG (2004), Deng WG (2004), Deng WG (2003)	8
SUMO2	0	HSPA8	4	pull down	Ouyang J (2009)	1
KMT2A	58	ASH2L	2	affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, biochemical, pull down	Yokoyama A (2004), Yokoyama A (2004), Yokoyama A (2004), Blobel GA (2009), Butler JS (2011), Mak AB (2010), Dharmarajan V (2012), Patel A (2014), Tang Z (2013), Li Y (2016), Alicea-Velazquez NL (2016), Weirich S (2017), Weirich S (2017)	13
HIPK2	0	EP300	36	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Aikawa Y (2006), Aikawa Y (2006), Aikawa Y (2006), Aikawa Y (2006)	4
NCOR1	9	ZMYND11	10	affinity chromatography technology	Masselink H (2000)	1
MYB	3	EP300	36	pull down, imaging technique, affinity chromatography technology, enzymatic study, pull down	Nicot C (2001), Jin W (2011), Sandberg ML (2005), Tomita A (2000), Uttarkar S (2015)	5
SMARCA2	17	KAT2B	2	affinity chromatography technology	Zhang Y (2010)	1
UBE2I	0	CREBBP	29	affinity chromatography technology, pull down, enzymatic study, two hybrid	Hsieh YL (2013), Hsieh YL (2013), Hsieh YL (2013), Liu ST (2012)	4
NCOR1	9	SKI	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Khan MM (2001), Tabata T (2009), Wu K (2003), He J (2003)	4
SMARCA2	17	EP300	36	affinity chromatography technology	Zhang Y (2010)	1
MYB	3	SIN3A	13	pull down, affinity chromatography technology, pull down	Nomura T (2004), Nomura T (2004), Nomura T (2004)	3
PIAS1	4	PML	7	affinity chromatography technology, affinity chromatography technology, enzymatic study	Rabellino A (2012), Rabellino A (2012), Rabellino A (2012)	3
UBE2I	0	PML	7	enzymatic study, pull down, enzymatic study, two hybrid, two hybrid, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, pull down	Knipscheer P (2008), Kim YE (2005), Satow R (2012), Duprez E (1999), Wang J (2011), Tatham MH (2003), Duprez E (1999), Gocke CB (2005), Lin DY (2006), Jo S (2016), Schilling EM (2017)	11
ZMYND11	10	UBE2I	0	two hybrid, affinity chromatography technology	Yu B (2009), Yu B (2009)	2
CEBPE	0	UBE2I	0	two hybrid, pull down	Chih DY (2004), Chih DY (2004)	2
CREBBP	29	WDR5	2	affinity chromatography technology	Koues OI (2009)	1
CCND3	1	CREBBP	29	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CCND3	1	MYB	3	two hybrid	Wang J (2011)	1
MYB	3	SND1	4	two hybrid, pull down	Dash AB (1996), Dash AB (1996)	2
TRIM28	1	PARP1	3	affinity chromatography technology	Quenet D (2008)	1
NCOR1	9	EP300	36	affinity chromatography technology	Cowger JJ (2006)	1
SUMO2	0	TRIM28	1	pull down	Ouyang J (2009)	1
SUMO2	0	PIAS1	4	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, pull down, pull down	Gocke CB (2008), Stehmeier P (2009), Stehmeier P (2009), Ullmann R (2012), Hecker CM (2006), Hecker CM (2006), Ullmann R (2012), Ullmann R (2012), Ouyang J (2009)	9
RBX1	2	HSPA8	4	affinity chromatography technology	Dias DC (2002)	1
NCOR1	9	CEBPB	2	affinity chromatography technology	Ki SH (2005)	1
KAT2B	2	PARP1	3	enzymatic study	Rajamohan SB (2009)	1
NLK	1	FBXW5	6	affinity chromatography technology	Kanei-Ishii C (2008)	1
SKI	3	NCL	1	affinity chromatography technology	Rashidian J (2015)	1
KMT2A	58	SMARCA2	17	affinity chromatography technology	Nakamura T (2002)	1
SUMO2	0	RPL4	4	pull down	Ouyang J (2009)	1
MYB	3	SP100	4	two hybrid	Ravasi T (2010)	1
FBXW5	6	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hu J (2008), He YJ (2006), Kanei-Ishii C (2012)	3
WDR5	2	KAT2B	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang YL (2008), Huttlin EL (2015), Huttlin EL (2017)	3
MYB	3	PAX5	7	affinity chromatography technology	Kishi H (2002)	1
NLK	1	LEF1	3	affinity chromatography technology, enzymatic study, enzymatic study, imaging technique	Ishitani T (2003), Li M (2010), Yasuda J (2003), Gupta K (2014)	4
SKI	3	HSPA8	4	affinity chromatography technology	Rashidian J (2015)	1
CUL4A	2	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
CREBBP	29	KAT5	1	affinity chromatography technology	Col E (2005)	1
PML	7	SUMO1	0	two hybrid, imaging technique, fluorescent resonance energy transfe, two hybrid, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, x-ray crystallography, fluorescent resonance energy transfe, unspecified method, two hybrid, pull down	Lin DY (2002), Cuchet-Lourenco D (2011), Percherancier Y (2009), Cuchet-Lourenco D (2012), Stehmeier P (2009), Duprez E (1999), Shen TH (2006), Shen TH (2006), Saether T (2007), Cappadocia L (2015), Cappadocia L (2015), Cappadocia L (2015), Li C (2017), Li C (2017)	14
PML	7	SP100	4	imaging technique, imaging technique, imaging technique, imaging technique, two hybrid, imaging technique	Cuchet-Lourenco D (2011), Cuchet-Lourenco D (2011), Cuchet D (2011), Negorev D (2001), Sternsdorf T (1997), Sahin U (2014)	6
NLK	1	SKI	3	affinity chromatography technology	Varjosalo M (2013)	1
DDB1	6	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down	Wang H (2006), Kapetanaki MG (2006), Hu J (2004), Ahn J (2010), Fischer ES (2011), Groisman R (2006)	6
KAT2B	2	CEBPB	2	enzymatic study, pull down	Wiper-Bergeron N (2007), Wiper-Bergeron N (2007)	2
EP300	36	PAX5	7	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	He T (2011), He T (2011), He T (2011), He T (2011)	4
SIN3A	13	SKI	3	pull down, affinity chromatography technology, affinity chromatography technology	Khan MM (2001), Inoue Y (2011), Wu K (2003)	3
KMT2A	58	NCL	1	biochemical	Havugimana PC (2012)	1
CUL4A	2	WDR5	2	affinity chromatography technology	Higa LA (2006)	1
HLF	0	CREBBP	29	two hybrid, pull down	Gradin K (2002), Gradin K (2002)	2
PML	7	KAT5	1	affinity chromatography technology, pull down	Wu Q (2009), Wu Q (2009)	2
SMARCA2	17	CHD3	19	affinity chromatography technology	Nakamura T (2002)	1
MYB	3	RBBP5	3	affinity chromatography technology	Jin S (2010)	1
ZMYND11	10	TRAF6	0	affinity chromatography technology, affinity chromatography technology	Wan J (2006), Ikeda O (2010)	2
MYB	3	MEN1	1	affinity chromatography technology	Jin S (2010)	1
MYB	3	MAF	4	pull down, two hybrid	Hedge SP (1998), Hedge SP (1998)	2
PML	7	SKI	3	affinity chromatography technology, pull down	Khan MM (2001), Khan MM (2001)	2
KMT2A	58	MEN1	1	biochemical, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Yokoyama A (2004), Yokoyama A (2004), Yokoyama A (2004), Blobel GA (2009), Bres V (2009), Terranova R (2006), Yokoyama A (2005), Yokoyama A (2005), Milne TA (2005), Milne TA (2005), Caslini C (2007)	11
CUL4A	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Angers S (2006), Jin J (2006), Wang H (2006), Kapetanaki MG (2006), Matsuda N (2005), Hu J (2004), Hu J (2004), Hu J (2004), Ahn J (2010), Maddika S (2009), Fischer ES (2011), Tan L (2007), He YJ (2006), He YJ (2006), He YJ (2006), McCall CM (2008), McCall CM (2008), Shiyanov P (1999), Bennett EJ (2010), Gastaldello S (2012), Kanei-Ishii C (2012), Hodgson AJ (2012), Kulaksiz G (2005), Wu Z (2012), Wu Z (2012), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Rao F (2014), Wan C (2015), Liu Y (2015), Zha Z (2015), Mouysset J (2015), Gao J (2015), Yang Y (2016), Yang Y (2016), Scherer PC (2016), Eichner R (2016), Mo Y (2017), Mo Y (2017), Peng Z (2016), Higa LA (2006), Ohtake F (2007)	46
MYB	3	FBXW5	6	affinity chromatography technology	Kanei-Ishii C (2012)	1
EP300	36	DDB1	6	affinity chromatography technology, affinity chromatography technology	Datta A (2001), Rapic-Otrin V (2002)	2
CEBPB	2	SMARCA2	17	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kowenz-Leutz E (1999), Kowenz-Leutz E (1999), Kowenz-Leutz E (1999), Christakos S (2007), Steinberg XP (2012), Jin J (2011)	6
SIN3A	13	CHD3	19	affinity chromatography technology	Nakamura T (2002)	1
GATA3	2	MYB	3	affinity chromatography technology	Kozuka T (2011)	1
FBXW5	6	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hu J (2008), He YJ (2006), Kanei-Ishii C (2012)	3
MAF	4	UBE2I	0	affinity chromatography technology	Leavenworth JW (2009)	1
UBE2I	0	SND1	4	enzymatic study	Matafora V (2009)	1
PML	7	WDR5	2	affinity chromatography technology	Hein MY (2015)	1
ZMYND11	10	MYB	3	pull down, two hybrid	Ladendorff NE (2001), Ladendorff NE (2001)	2
SMARCA2	17	CREBBP	29	affinity chromatography technology	Zhang Y (2010)	1
LEF1	3	STAT5A	4	affinity chromatography technology, imaging technique	Gupta K (2014), Gupta K (2014)	2
MYB	3	UPF2	2	pull down	Miyamoto-Sato E (2010)	1
FBXW7	2	SIN3A	13	affinity chromatography technology	Kourtis N (2015)	1
CEBPE	0	PIAS1	4	two hybrid, pull down, affinity chromatography technology	Chih DY (2004), Chih DY (2004), Chih DY (2004)	3
MYB	3	DDB1	6	affinity chromatography technology	Kanei-Ishii C (2012)	1
MYB	3	NCL	1	affinity chromatography technology	Ying GG (2000)	1
DDB1	6	KAT2A	1	affinity chromatography technology, pull down, affinity chromatography technology	Martinez E (2001), Martinez E (2001), Li Y (2011)	3
UBE2I	0	SP100	4	enzymatic study, pull down, two hybrid, enzymatic study, enzymatic study, enzymatic study	Knipscheer P (2008), Knipscheer P (2008), Bandyopadhyay S (2010), Pelisch F (2010), Meulmeester E (2008), Knipscheer P (2007)	6
RBBP5	3	KMT2A	58	affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, pull down	Yokoyama A (2004), Yokoyama A (2004), Yokoyama A (2004), Blobel GA (2009), Dou Y (2005), Dharmarajan V (2012), Hu D (2013), Tang Z (2013), Alicea-Velazquez NL (2016), Weirich S (2017), Weirich S (2017)	11
WDR5	2	TRAF6	0	affinity chromatography technology	Wang YY (2010)	1
HIPK2	0	FBXW7	2	affinity chromatography technology	Kanei-Ishii C (2008)	1
KAT2A	1	MYB	3	enzymatic study	Tomita A (2000)	1
SUMO1	0	MYB	3	pull down	Saether T (2011)	1
MYB	3	FBXW7	2	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kanei-Ishii C (2008), Kanei-Ishii C (2008), Kitagawa K (2010), Kitagawa K (2010)	4
MYB	3	ERC2	7	pull down	Miyamoto-Sato E (2010)	1
MEN1	1	WDR5	2	biochemical, affinity chromatography technology, affinity chromatography technology	Yokoyama A (2004), Hughes CM (2004), Hauri S (2016)	3
TRIM28	1	CHD3	19	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Stelzl U (2005), Goodarzi AA (2011), Goodarzi AA (2011), Ivanov AV (2007), Garvin AJ (2013)	5
SUMO2	0	CHD3	19	two hybrid, two hybrid, two hybrid, unspecified method	Stelzl U (2005), Vinayagam A (2011), Goehler H (2004), Garvin AJ (2013)	4
CEBPB	2	CREBBP	29	pull down	Kovacs KA (2003)	1
SUMO1	0	PIAS1	4	two hybrid, two hybrid, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, pull down, pull down	Lee BH (2003), Kahyo T (2001), Stehmeier P (2009), Stehmeier P (2009), Stehmeier P (2009), Ullmann R (2012), Ullmann R (2012), Hecker CM (2006), Hecker CM (2006), Gocke CB (2008), Ullmann R (2012), Ledsaak M (2016)	12
CUL4A	2	NCL	1	affinity chromatography technology	Bennett EJ (2010)	1
SKI	3	HIPK2	0	pull down, pull down, affinity chromatography technology	Harada J (2003), Harada J (2003), Harada J (2003)	3
CREBBP	29	SUMO1	0	x-ray crystallography, pull down	Diehl C (2016), Diehl C (2016)	2
MYB	3	NCOR1	9	pull down, affinity chromatography technology, pull down	Nomura T (2004), Nomura T (2004), Nomura T (2004)	3
MEN1	1	HSPA8	4	affinity chromatography technology	Yaguchi H (2004)	1
HIPK2	0	PML	7	affinity chromatography technology, enzymatic study, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study	de la Vega L (2011), Renner F (2010), Sung KS (2011), Sung KS (2011), Gresko E (2009), Gresko E (2009), Gresko E (2009)	7
MEN1	1	RBBP5	3	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yokoyama A (2004), MacConaill LE (2006), Hughes CM (2004), Hughes CM (2004), Hughes CM (2004)	5
HIPK2	0	PARP1	3	affinity chromatography technology, pull down, affinity chromatography technology	Choi JR (2016), Choi JR (2016), Choi JR (2016)	3
RBBP5	3	WDR5	2	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yokoyama A (2004), Lee JH (2005), Higa LA (2006), Wysocka J (2005), Wysocka J (2005), Patel SR (2007), Cho YW (2007), Avdic V (2011), Avdic V (2011), Avdic V (2011), Mo R (2006), Gan Q (2011), Mak AB (2010), Mak AB (2010), Wu MZ (2011), Huttlin EL (2015), Bailey JK (2015), Huttlin EL (2017), Carugo A (2016), Hauri S (2016)	20
MAF	4	CREBBP	29	affinity chromatography technology, affinity chromatography technology	Chen Q (2002), Chen Q (2002)	2
ASH2L	2	RBBP5	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, pull down	Yokoyama A (2004), Lee JH (2005), Lee JH (2005), Garapaty S (2009), Wysocka J (2005), Patel SR (2007), Patel SR (2007), Cho YW (2007), Cho YW (2007), Butler JS (2011), Avdic V (2011), Mo R (2006), Mo R (2006), Cao F (2010), Cao F (2010), Mak AB (2010), Mak AB (2010), Rolland T (2014), Tang Z (2013), Yu H (2011), Li Y (2016)	21
LEF1	3	EP300	36	enzymatic study, affinity chromatography technology, pull down	Hecht A (2003), Hecht A (2003), Hecht A (2003)	3
PML	7	SIN3A	13	pull down, affinity chromatography technology	Khan MM (2001), Khan MM (2001)	2
CREBBP	29	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Dohda T (2004), Dohda T (2004)	3
UBE2I	0	HIPK2	0	two hybrid, two hybrid, two hybrid, pull down, two hybrid, enzymatic study	Lee BH (2003), Bandyopadhyay S (2010), Sung KS (2005), Sung KS (2005), Hofmann TG (2005), Sung KS (2005)	6
PML	7	NCOR1	9	pull down, affinity chromatography technology, two hybrid, pull down	Khan MM (2001), Khan MM (2001), Khan MM (2001), Minucci S (2000)	4
NCOR1	9	PIAS1	4	pull down, two hybrid, affinity chromatography technology	Tiefenbach J (2006), Tiefenbach J (2006), Tiefenbach J (2006)	3
ASH2L	2	WDR5	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yokoyama A (2004), Lee JH (2005), Wysocka J (2005), McKinnell IW (2008), McKinnell IW (2008), Patel SR (2007), Butler JS (2011), Mo R (2006), Gan Q (2011), Gan Q (2011), Mak AB (2010), Mak AB (2010), Wu MZ (2011), Havugimana PC (2012), Tang Z (2013), Huttlin EL (2015), Bailey JK (2015), Huttlin EL (2017), Hauri S (2016)	19
HSPA8	4	CREBBP	29	affinity chromatography technology	Du C (2017)	1
WDR5	2	KMT2A	58	affinity chromatography technology, biochemical, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, unspecified method, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, pull down, affinity chromatography technology	Yokoyama A (2004), Yokoyama A (2004), Yokoyama A (2004), Song JJ (2008), Avdic V (2011), Paggetti J (2010), Mak AB (2010), Dharmarajan V (2012), Dharmarajan V (2012), Zhang P (2012), Senisterra G (2013), Tang Z (2013), Shinsky SA (2014), Huttlin EL (2015), Huttlin EL (2017), Alicea-Velazquez NL (2016), Weirich S (2017), Weirich S (2017), Hauri S (2016)	19
CREBBP	29	PARP1	3	enzymatic study, imaging technique	Hassa PO (2005), Chen H (2014)	2
KAT5	1	UBE2I	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cheng Z (2008), Cheng Z (2008), Cheng Z (2008)	3
EP300	36	STAT5A	4	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Pfitzner E (1998), Pfitzner E (1998), Pfitzner E (1998), Kotla S (2015)	4
HIPK2	0	MYB	3	pull down, two hybrid, affinity chromatography technology	Kurahashi T (2005), Kanei-Ishii C (2004), Kanei-Ishii C (2004)	3
EP300	36	WDR5	2	affinity chromatography technology	Tang Z (2013)	1
MYB	3	KMT2A	58	affinity chromatography technology	Jin S (2010)	1
NCOR1	9	CREBBP	29	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Cowger JJ (2006), Cowger JJ (2006), Cowger JJ (2006), Cowger JJ (2006)	4
MYB	3	PPM1K	0	two hybrid	Wang J (2011)	1
NCOR1	9	TRIM28	1	biochemical, affinity chromatography technology	Underhill C (2000), Nomura T (2004)	2
MYB	3	MYOZ2	2	two hybrid	Wang J (2011)	1
RBX1	2	CCND3	1	affinity chromatography technology	Maeda I (2001)	1
MYB	3	ASH2L	2	affinity chromatography technology	Jin S (2010)	1
EP300	36	KAT5	1	affinity chromatography technology, affinity chromatography technology	Col E (2005), Col E (2005)	2
KAT2A	1	CUL4A	2	affinity chromatography technology	Li Y (2011)	1
STAT5A	4	NLK	1	imaging technique	Gupta K (2014)	1
EP300	36	RBBP5	3	affinity chromatography technology	Tang Z (2013)	1
HIPK2	0	CREBBP	29	affinity chromatography technology, affinity chromatography technology	Hofmann TG (2002), Hofmann TG (2002)	2
DDB1	6	SIN3A	13	affinity chromatography technology, affinity chromatography technology, pull down	Ji Q (2014), Ji Q (2014), Ji Q (2014)	3
KAT2A	1	CEBPB	2	enzymatic study, pull down, affinity chromatography technology	Wiper-Bergeron N (2007), Wiper-Bergeron N (2007), Wiper-Bergeron N (2007)	3
SUMO2	0	HIPK2	0	pull down	de la Vega L (2011)	1
CREBBP	29	SND1	4	affinity chromatography technology	Vaelineva T (2005)	1
MYB	3	PARP1	3	affinity chromatography technology	Shi L (2008)	1
CREBBP	29	KAT2B	2	pull down, biochemical, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Tini M (2002), Cho H (1998), Cho H (1998), Cho H (1998), Korzus E (1998), Korzus E (1998), Korzus E (1998), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996)	10
UBE2I	0	TRIM28	1	affinity chromatography technology, pull down, enzymatic study, pull down	Liang Q (2011), Garvin AJ (2013), Ivanov AV (2007), Neo SH (2015)	4
RBBP5	3	DDB1	6	affinity chromatography technology	Higa LA (2006)	1
MYB	3	UBE2I	0	two hybrid, enzymatic study	Bies J (2002), Kanei-Ishii C (2012)	2
RPL4	4	MYB	3	affinity chromatography technology, pull down	Egoh A (2010), Egoh A (2010)	2
RPL4	4	SND1	4	biochemical	Havugimana PC (2012)	1
ZMYND11	10	PIAS1	4	two hybrid, affinity chromatography technology	Yu B (2009), Yu B (2009)	2
MYB	3	CEBPB	2	x-ray crystallography	Tahirov TH (2002)	1
KMT2A	58	CHD3	19	affinity chromatography technology	Nakamura T (2002)	1
MEN1	1	SIN3A	13	pull down, affinity chromatography technology	Kim H (2003), Kim H (2003)	2
KMT2A	58	SIN3A	13	affinity chromatography technology, affinity chromatography technology	Yokoyama A (2010), Nakamura T (2002)	2
NCL	1	RPL4	4	biochemical, affinity chromatography technology	Havugimana PC (2012), Salvetti A (2016)	2
NLK	1	HIPK2	0	two hybrid, pull down	Kanei-Ishii C (2004), Kanei-Ishii C (2004)	2
LEF1	3	MYB	3	affinity chromatography technology	Zhou F (2011)	1
RBX1	2	CUL4A	2	affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, biochemical, enzymatic study, pull down, biochemical	Dias DC (2002), Ohta T (1999), Guerrero-Santoro J (2008), Hu J (2004), Furukawa M (2002), Maddika S (2009), Tron AE (2012), Tron AE (2012), He YJ (2006), Gastaldello S (2012), Olma MH (2009), Kristensen AR (2012), Huang DT (2009), Pick E (2007), Yang Y (2016), Scherer PC (2016), Nguyen TV (2016)	17
CREBBP	29	KMT2A	58	pull down, x-ray crystallography, pull down, pull down, affinity chromatography technology, two hybrid, x-ray crystallography, pull down	Goto NK (2002), Goto NK (2002), Ernst P (2001), Ernst P (2001), Ernst P (2001), Ernst P (2001), Yang F (2006), Ramirez JA (2007)	8
UBE2I	0	CHD3	19	two hybrid	Lee BH (2003)	1
UBE2I	0	KAT2A	1	enzymatic study	Gocke CB (2005)	1
EP300	36	SUMO2	0	pull down, enzymatic study	Ullmann R (2012), Ullmann R (2012)	2
HSPA8	4	MYB	3	affinity chromatography technology	Li L (2013)	1
CHD3	19	MYB	3	affinity chromatography technology, pull down	Saether T (2007), Saether T (2007)	2
MAF	4	SIN3A	13	affinity chromatography technology	Hu HM (2007)	1
SUMO2	0	PML	7	imaging technique, two hybrid, pull down	Cuchet-Lourenco D (2011), Li C (2017), Li C (2017)	3
UBE2I	0	SUMO1	0	affinity chromatography technology, pull down, two hybrid, two hybrid, fluorescent resonance energy transfe, pull down, two hybrid, two hybrid, pull down, pull down, two hybrid, pull down, fluorescent resonance energy transfe, pull down, two hybrid, pull down, pull down, enzymatic study, enzymatic study, biochemical, affinity chromatography technology	Ewing RM (2007), Tatham MH (2003), Minty A (2000), Shen Z (1996), Song Y (2011), Knipscheer P (2007), Boutell C (2011), Gong L (1997), Gong L (1997), Hemelaar J (2004), Hecker CM (2006), Hecker CM (2006), Martin SF (2008), Everett RD (2014), Rolland T (2014), Zilio N (2013), Carbia-Nagashima A (2007), Knipscheer P (2007), Matic I (2008), Wan C (2015), Hein MY (2015)	21
UBE2I	0	PIAS1	4	two hybrid, pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down	Lee BH (2003), Sapetschnig A (2002), Kahyo T (2001), Bandyopadhyay S (2010), Driscoll JJ (2010), Kahyo T (2001), Yin Y (2012), Gocke CB (2005), van den Akker E (2005), Ogawa H (2009), Schmidt D (2002), Gibbs-Seymour I (2015)	12
UBE2I	0	RBBP5	3	enzymatic study	Nayak A (2014)	1