Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications
MSH2	4436	PEMBROLIZUMAB	CHEMBL3137343		OncoKB	27718784, 25891304, 26028407, 26970723, 26800463, 25399552, 20525992, 27733243, 28212060, 25891173, 26028255, 27451390, 26952546, 25840693, 26559592, 27718847, 26406148
MSH2	4436	DURVALUMAB	CHEMBL3301587		CIViC	26674132
MSH2	4436	IPILIMUMAB	CHEMBL1789844		OncoKB	27718784, 25891304, 26028407, 26970723, 26800463, 25399552, 20525992, 27733243, 28212060, 25891173, 26028255, 27451390, 26952546, 25840693, 26559592, 27718847, 26406148
MSH2	4436	NIVOLUMAB	CHEMBL2108738		OncoKB	27718784, 25891304, 26028407, 26970723, 26800463, 25399552, 20525992, 27733243, 28212060, 25891173, 26028255, 27451390, 26952546, 25840693, 26559592, 27718847, 26406148
MSH2	4436	ATEZOLIZUMAB	CHEMBL3707227		OncoKB	27718784, 25891304, 26028407, 26970723, 26800463, 25399552, 20525992, 27733243, 28212060, 25891173, 26028255, 27451390, 26952546, 25840693, 26559592, 27718847, 26406148

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
MSH2	rs1863332	G	fluorouracil	efficacy	no	1,002 patients with gastric cancer and complete genotyping data were included; 694 had chemotherapy treatment, and 308 did not. Median follow-up time was 63.43 months, with 465 deaths (46.4%) at the end. Patients were treated with fluoropyridines, platinum-based chemotherapy, or radiotherapy combinations. Please note: the authors do not distinguish between distinct treatment regimens- simply "chemotherapy".	Allele G is not associated with response to fluorouracil, Platinum compounds and radiotherapy in people with Stomach Neoplasms as compared to allele T.	28796378	1448926630