Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
RFPL4B rs9384825 T tramadol metabolism/PK not stated The T allele was significantly associated with decreased conversion of tramadol to M1 in post-mortem cases in the discovery cohort, but this was not replicated. Note that the authors did not assess the CYP2D6 genotype/phenotype of subjects. Allele T is associated with decreased metabolism of tramadol as compared to allele C. 30971809 1451101220