PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
MAGEC2	0	MNAT1	0	two hybrid	Kozakova L (2015)	1
ESR1	0	MNAT1	0	pull down, affinity chromatography technology	Talukder AH (2003), Talukder AH (2003)	2
ESR1	0	8339	0	pull down	Nalvarte I (2010)	1
CCNH	3	GTF2H4	2	biochemical	Havugimana PC (2012)	1
TP53	0	RPA1	0	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Romanova LY (2004), Romanova LY (2004), Riva F (2001), Glanzer JG (2013)	4
TRIM21	0	TRIM5	4	pull down	Li X (2006)	1
BRCA1	7	RB1	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, pull down, pull down, affinity chromatography technology, genetic interference	Aprelikova ON (1999), Fan S (2001), Fan S (2001), Fan S (2001), Yarden RI (1999), Aprelikova ON (1999), Aprelikova ON (1999), Shen JP (2017)	8
RPA1	0	MNAT1	0	affinity chromatography technology	Marechal A (2014)	1
CDK7	0	GTF2H1	0	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Rossignol M (1997), Shiekhattar R (1995), Yee A (1995), Kershnar E (1998), Reardon JT (1996), Varjosalo M (2013)	6
USP2	0	MNAT1	0	two hybrid	Hayes SD (2012)	1
RPA3	2	RPA2	0	biochemical, x-ray crystallography, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Bochkareva E (1998), Bochkareva E (2002), Havugimana PC (2012), Du Y (2009), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	7
BRCA1	7	5430	0	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Krum SA (2003), Scully R (1997), Scully R (1997), Chiba N (2001), Chiba N (2001), Krum SA (2003), Starita LM (2005), Woods NT (2012), Bennett CB (2008), Hill SJ (2014), Winton CE (2016)	11
GTF2H2	0	GTF2H4	2	affinity chromatography technology, biochemical, biochemical, pull down	Vermeulen W (2000), Havugimana PC (2012), Wan C (2015), Luo J (2015)	4
GTF2H1	0	GTF2H4	2	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
NKX3-1	2	SP1	0	two hybrid	Simmons SO (2006)	1
POU2F2	2	MNAT1	0	pull down	Inamoto S (1997)	1
GTF2H5	0	MNAT1	0	affinity chromatography technology	Hein MY (2015)	1
MNAT1	0	TRIM2	1	two hybrid	Woodsmith J (2012)	1
GTF2H3	2	GTF2H1	0	pull down, biochemical, affinity chromatography technology, pull down, biochemical, biochemical, affinity chromatography technology, pull down	Chymkowitch P (2011), Humbert S (1994), Humbert S (1994), Jawhari A (2002), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Luo J (2015)	8
USP2	0	TRIM39	0	two hybrid	Hayes SD (2012)	1
TP53	0	GTF2H4	2	far western blotting	Leveillard T (1996)	1
CDK7	0	CDK2	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Drapkin R (1996), Cheng A (2005), Xu X (1999), Higashi H (1996), Aprelikova O (1995), Moisan A (2004), Larochelle S (2012), Larochelle S (2006), Larochelle S (2006), Garrett S (2001), Garrett S (2001), Lolli G (2004), Varjosalo M (2013), So J (2015)	14
ERCC3	3	CDK7	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Giglia-Mari G (2004), Rossignol M (1997), Yee A (1995), Jeronimo C (2007), Jeronimo C (2007), Reardon JT (1996), Chen D (1999), Varjosalo M (2013), Huttlin EL (2017), Luo J (2015)	10
RPA1	0	RPA2	0	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shao RG (1999), Bochkareva E (2002), Gong Z (2011), Havugimana PC (2012), Kristensen AR (2012), Ghospurkar PL (2014), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Elia AE (2015), Elia AE (2015), Huttlin EL (2017), Feeney L (2017)	13
RPA2	0	CCNH	3	affinity chromatography technology	Marechal A (2014)	1
RNF32	0	MKRN3	2	two hybrid	Woodsmith J (2012)	1
CDK7	0	MTA1	3	affinity chromatography technology	Talukder AH (2003)	1
MNAT1	0	TRIM21	0	two hybrid	Woodsmith J (2012)	1
CDK7	0	CCNH	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down	Maekelae TP (1994), Maekelae TP (1994), Maekelae TP (1994), Maekelae TP (1994), Yee A (1995), Garber ME (2000), Garber ME (2000), Jeronimo C (2007), Reardon JT (1996), Liu J (1997), Cujec TP (1997), Epie N (2005), Bockstaele L (2006), Tassan JP (1995), Chen D (1999), Havugimana PC (2012), Poterszman A (1997), Nguyen VT (2001), Garrett S (2001), Pinhero R (2004), Varjosalo M (2013), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Luo J (2015)	25
7495	0	MNAT1	0	affinity chromatography technology	Busso D (2000)	1
TRIM14	1	RPA3	2	bioid	Tan P (2017)	1
MNAT1	0	GTF2H3	2	biochemical	Havugimana PC (2012)	1
MNAT1	0	TRIM31	0	two hybrid	Woodsmith J (2012)	1
COPS6	0	CDK2	0	affinity chromatography technology	Bennett EJ (2010)	1
MAGEE2	0	MNAT1	0	two hybrid	Kozakova L (2015)	1
ERCC3	3	CCNH	3	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Giglia-Mari G (2004), Jeronimo C (2007), Drapkin R (1996), Drapkin R (1996), Huttlin EL (2015), Huttlin EL (2017), Luo J (2015)	7
MTA1	3	MNAT1	0	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Talukder AH (2003), Talukder AH (2003), Talukder AH (2003), Talukder AH (2003), Talukder AH (2003)	5
MNAT1	0	RNF7	0	two hybrid	Woodsmith J (2012)	1
POU5F1	0	EEF1A1	0	affinity chromatography technology	Hawkins PG (2010)	1
GTF2H1	0	RPA1	0	affinity chromatography technology	Araujo SJ (2001)	1
MKRN3	2	RNF7	0	two hybrid	Woodsmith J (2012)	1
SP1	0	ESR1	0	imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Koslowski M (2009), Jin W (2008), Dong J (2006), Dong J (2006), Castet A (2006), He S (2005), He S (2005), Varshochi R (2005), Varshochi R (2005), Petz LN (2004), Li D (2007), Itoh Y (2007), Saville B (2000), Gibson LL (2005)	14
GTF2H5	0	CDK7	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Giglia-Mari G (2004), Varjosalo M (2013), Hein MY (2015)	3
EGLN3	0	ERCC3	3	affinity chromatography technology	Rodriguez J (2016)	1
ERCC3	3	GTF2H3	2	biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Giglia-Mari G (2004), Marinoni JC (1997), Jeronimo C (2007), Humbert S (1994), Humbert S (1994), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Luo J (2015)	9
ICK	1	MNAT1	0	affinity chromatography technology	Fu Z (2006)	1
MNAT1	0	HPS6	8	two hybrid	Stelzl U (2005)	1
POU2F1	5	ESR1	0	pull down	Prefontaine GG (1999)	1
TP53	0	RPA2	0	affinity chromatography technology	Li X (2015)	1
CDK2	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Shintani S (2000), Nair JS (2009), Takaki T (2004), Shen WH (2004), He W (2003), Peiretti A (2003), Harbour JW (1999), Horton LE (1997), Higashi H (1996), Delston RB (2011), Kim KS (2002), Chen W (2004), Liberal V (2012), Boyer Arnold N (2005), Dynlacht BD (1997), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Hara E (1997), Connell-Crowley L (1997), Matsuura I (2004), Chen J (1996), Gaiddon C (2003), Seo DW (2006), Zarkowska T (1997), Grimmler M (2007), Nakanishi M (1999), Pevarello P (2005), Iyer NG (2007), Chan HM (2001), Pan W (2001)	32
GTF2H1	0	MNAT1	0	biochemical, biochemical, pull down	Kershnar E (1998), Havugimana PC (2012), Luo J (2015)	3
MNAT1	0	BRCA1	7	affinity chromatography technology, two hybrid	Moisan A (2004), Woodsmith J (2012)	2
MAGEE2	0	TRIM31	0	affinity chromatography technology	Kozakova L (2015)	1
MNAT1	0	SFR1	0	biochemical	Wan C (2015)	1
POU5F1	0	MNAT1	0	pull down	Inamoto S (1997)	1
5430	0	GTF2H4	2	biochemical, pull down	Scully R (1997), Scully R (1997)	2
CDK2	0	TRIM21	0	affinity chromatography technology	Neganova I (2011)	1
GTF2H1	0	RPA2	0	affinity chromatography technology	Araujo SJ (2001)	1
TRIM34	1	MKRN3	2	two hybrid	Woodsmith J (2012)	1
RPA2	0	COPS6	0	two hybrid	Stelzl U (2005)	1
USP2	0	TRIM9	3	two hybrid	Hayes SD (2012)	1
NKX3-1	2	MNAT1	0	two hybrid	Wang X (2008)	1
CDK7	0	BRCA1	7	affinity chromatography technology	Moisan A (2004)	1
SP1	0	MNAT1	0	affinity chromatography technology	Chuang JY (2012)	1
MNAT1	0	RNF32	0	two hybrid	Woodsmith J (2012)	1
BRCA1	7	POU2F1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Fan W (2002), Hosey AM (2007), Hosey AM (2007), Harte MT (2010)	4
TRIM39	0	TP53	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhang L (2012), Zhang L (2012), Zhang L (2012)	3
TP53	0	GTF2H1	0	pull down, pull down, pull down, pull down, far western blotting, pull down, x-ray crystallography	Xiao H (1994), Di Lello P (2008), Okuda M (2008), Leveillard T (1996), Leveillard T (1996), Di Lello P (2006), Di Lello P (2006)	7
CCNH	3	MNAT1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, biochemical, affinity chromatography technology	Ewing RM (2007), Talukder AH (2003), Bockstaele L (2006), Havugimana PC (2012), Pinhero R (2004), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	8
USP2	0	TRIM5	4	two hybrid	Hayes SD (2012)	1
GTF2H5	0	GTF2H1	0	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
SUPT5H	2	CCNH	3	pull down	Garber ME (2000)	1
MNAT1	0	MKRN3	2	two hybrid	Woodsmith J (2012)	1
CCNH	3	MTA1	3	affinity chromatography technology	Talukder AH (2003)	1
SIRT6	2	SUPT5H	2	affinity chromatography technology	Simeoni F (2013)	1
CDK2	0	TP53	0	enzymatic study, enzymatic study, imaging technique	Luciani MG (2000), Tsai CH (2009), Chen TC (2014)	3
EGLN3	0	5430	0	affinity chromatography technology	Rodriguez J (2016)	1
5430	0	RPA1	0	affinity chromatography technology	Fousteri M (2006)	1
BRCA1	7	RPA1	0	affinity chromatography technology, imaging technique, affinity chromatography technology	Suhasini AN (2011), Mok MT (2010), Tian F (2013)	3
RPA1	0	CCNH	3	affinity chromatography technology	Marechal A (2014)	1
TP53	0	MTA1	3	pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Yao YL (2003), Li DQ (2010), Moon HE (2007), Moon HE (2007), Li DQ (2009), Li DQ (2009)	6
TRIM21	0	TRIM39	0	two hybrid, two hybrid	Woodsmith J (2012), Rolland T (2014)	2
CDK7	0	ESR1	0	enzymatic study	Chen D (2000)	1
BRCA1	7	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2003), Maor S (2007), Maor S (2007), Abramovitch S (2003)	4
GTF2H1	0	CCNH	3	biochemical, biochemical, affinity chromatography technology	Shiekhattar R (1995), Kershnar E (1998), Araujo SJ (2001)	3
TRIM14	1	COPS6	0	bioid	Tan P (2017)	1
RPA3	2	CDK7	0	affinity chromatography technology	Marechal A (2014)	1
MNAT1	0	GTF2H2	0	affinity chromatography technology, pull down	Drapkin R (1996), Luo J (2015)	2
MNAT1	0	COPS6	0	two hybrid	Stelzl U (2005)	1
MNAT1	0	5430	0	enzymatic study, enzymatic study	Larochelle S (2006), Lolli G (2004)	2
CDK7	0	MNAT1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down	Talukder AH (2003), Yee A (1995), Jeronimo C (2007), Busso D (2000), Cujec TP (1997), Tassan JP (1995), Chen D (1999), Havugimana PC (2012), Varjosalo M (2013), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Luo J (2015)	13
CDK7	0	GTF2H3	2	affinity chromatography technology, pull down, affinity chromatography technology	Jeronimo C (2007), Chymkowitch P (2011), Varjosalo M (2013)	3
EGLN3	0	MNAT1	0	affinity chromatography technology	Rodriguez J (2016)	1
ERCC3	3	ERCC2	4	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down	Giglia-Mari G (2004), Marinoni JC (1997), Drapkin R (1994), Iyer N (1996), Iyer N (1996), Havugimana PC (2012), Stehling O (2012), Luo J (2015), Luo J (2015)	9
SP1	0	RB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Singh J (2002), Chang YC (2001), Opitz OG (2000)	3
ERCC2	4	GTF2H1	0	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Drapkin R (1994), Rossignol M (1997), Seroz T (2000), Luo J (2015), Luo J (2015)	5
GTF2H5	0	ERCC2	4	affinity chromatography technology	Hein MY (2015)	1
ERCC2	4	MNAT1	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down	Busso D (2000), Havugimana PC (2012), Huttlin EL (2015), Huttlin EL (2017), Luo J (2015)	5
EGLN3	0	HPS6	8	affinity chromatography technology	Rodriguez J (2016)	1
MNAT1	0	RNF41	2	two hybrid	Woodsmith J (2012)	1
MNAT1	0	TRIM9	3	two hybrid	Woodsmith J (2012)	1
TP53	0	ERCC3	3	pull down, affinity chromatography technology, pull down, pull down, pull down	Wang XW (1995), Wang XW (1995), Qadri I (2002), Qadri I (2002), Leveillard T (1996)	5
RB1	2	GTF2H1	0	biochemical	Havugimana PC (2012)	1
ERCC3	3	GTF2H1	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Giglia-Mari G (2004), Marinoni JC (1997), Rossignol M (1997), Jeronimo C (2007), Drapkin R (1996), Araujo SJ (2001), Havugimana PC (2012), Maru Y (1999), Wan C (2015), Huttlin EL (2017), Luo J (2015), Luo J (2015)	12
RPA2	0	GTF2H3	2	affinity chromatography technology	Marechal A (2014)	1
GTF2H3	2	GTF2H2	0	pull down, affinity chromatography technology, pull down, biochemical, biochemical, affinity chromatography technology, pull down	Chymkowitch P (2011), Kellenberger E (2005), Jawhari A (2002), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Luo J (2015)	7
ICK	1	TP53	0	affinity chromatography technology	Varjosalo M (2013)	1
TP53	0	EEF1A1	0	affinity chromatography technology	Fogeron ML (2013)	1
GTF2H1	0	5430	0	enzymatic study, biochemical, enzymatic study	Moisan A (2004), Yankulov K (1999), Parada CA (1996)	3
EGLN3	0	MCM7	5	affinity chromatography technology	Rodriguez J (2016)	1
CDK2	0	ESR1	0	enzymatic study, affinity chromatography technology	Zhou W (2014), Zhou W (2014)	2
CDK7	0	SUPT5H	2	enzymatic study, pull down, enzymatic study	Garber ME (2000), Garber ME (2000), Larochelle S (2006)	3
MNAT1	0	GTF2H4	2	biochemical	Havugimana PC (2012)	1
RPA3	2	EEF1A1	0	affinity chromatography technology	Marechal A (2014)	1
BRCA1	7	SUPT5H	2	affinity chromatography technology, affinity chromatography technology	Bennett CB (2008), Bennett CB (2008)	2
CDK7	0	ERCC2	4	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Reardon JT (1996), Havugimana PC (2012), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	5
GTF2H2	0	GTF2H5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Giglia-Mari G (2004), Vermeulen W (2000), Giglia-Mari G (2006), Hein MY (2015), Huttlin EL (2017)	5
8339	0	MNAT1	0	bioid	Lambert JP (2015)	1
EGLN3	0	CDK2	0	affinity chromatography technology	Rodriguez J (2016)	1
TRIM17	5	TRIM39	0	two hybrid, two hybrid, two hybrid	Rual JF (2005), Woodsmith J (2012), Rolland T (2014)	3
TP53	0	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Borellini F (1993), Jin W (2008), Dhar SK (2006), Lagger G (2003), Lagger G (2003), Lagger G (2003), Lagger G (2003), Sengupta S (2005), Sengupta S (2005), Lin RK (2010), Kim HA (2011), Sawaya BE (1998), St Clair S (2004), Innocente SA (2005), Innocente SA (2005), Ohlsson C (1998), Kong X (2013), Bocangel D (2009), Bocangel D (2009)	19
MCM7	5	RB1	2	two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Sterner JM (1998), Sterner JM (1998), Sterner JM (1998), Liu P (2006), Gladden AB (2003)	5
RPA2	0	LRIF1	3	two hybrid	Stelzl U (2005)	1
TRIM5	4	MKRN3	2	two hybrid	Woodsmith J (2012)	1
CCNH	3	BRCA1	7	affinity chromatography technology	Moisan A (2004)	1
CDK2	0	MNAT1	0	affinity chromatography technology	Varjosalo M (2013)	1
EGLN3	0	BRCA1	7	affinity chromatography technology	Rodriguez J (2016)	1
CDK7	0	MCM7	5	affinity chromatography technology	Wang Y (2000)	1
ERCC3	3	GTF2H2	0	biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down	Giglia-Mari G (2004), Marinoni JC (1997), Jeronimo C (2007), Humbert S (1994), Humbert S (1994), Wan C (2015), Huttlin EL (2017), Luo J (2015), Luo J (2015)	9
5430	0	PCIF1	0	pull down, affinity chromatography technology, affinity chromatography technology	Fan H (2003), Fan H (2003), Hein MY (2015)	3
MNAT1	0	TRIM17	5	two hybrid	Woodsmith J (2012)	1
ERCC3	3	GTF2H4	2	biochemical, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, pull down	Giglia-Mari G (2004), Marinoni JC (1997), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Luo J (2015), Luo J (2015)	7
MNAT1	0	RBM48	1	two hybrid	Stelzl U (2005)	1
EGLN3	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
MDM4	0	TP53	0	enzymatic study, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, protein complementation assay, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, fluorescent resonance energy transfe, pull down	Badciong JC (2002), Shvarts A (1997), Shvarts A (1997), Tang Y (2008), Okamoto K (2005), Chen L (2005), Wang X (2001), Ohtsubo C (2009), Zdzalik M (2010), Singh RK (2007), Kim S (2010), Li M (2011), Li M (2011), David Y (2011), de Graaf P (2003), Wade M (2012), Wade M (2012), Wade M (2012), Stad R (2000), Stad R (2000), Bernal F (2010), Bernal F (2010), Bernal F (2010), Bernal F (2010), Miller KR (2010), Zuckerman V (2009), Kallen J (2009), Czarna A (2009), Czarna A (2009), Popowicz GM (2008), Hu B (2007), Sharp DA (1999), Li C (2002), Di Conza G (2012), Mancini F (2009), Mancini F (2009), Wu S (2012), Shan B (2012), Wu S (2012), Wu S (2012), Ranaweera RS (2013), Bista M (2013), Bista M (2013), Wang CL (2014), Wang CL (2014), Rallapalli R (1999), Chang YS (2013), Chang YS (2013), Tan BX (2014), Huttlin EL (2015), Sanchez MC (2010), Sanchez MC (2010), Li YC (2014), Li X (2015), Chen X (2015), Chen L (2015), Chen L (2015), Chen L (2015), Wei X (2016), Wei X (2016), Xie X (2016), Huttlin EL (2017), Borcherds W (2017), Shangary S (2008), Ivanov AA (2017), Mancini F (2016)	66
DMAP1	2	MNAT1	0	affinity chromatography technology, two hybrid	Kang BG (2007), Kang BG (2007)	2
TRIM14	1	MNAT1	0	two hybrid	Tan P (2017)	1
GTF2H5	0	ERCC3	3	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Giglia-Mari G (2004), Giglia-Mari G (2004), Giglia-Mari G (2006), Hein MY (2015), Huttlin EL (2017), Luo J (2015)	6
MNAT1	0	BEX3	0	two hybrid	Wang J (2011)	1
BRCA1	7	GTF2H4	2	biochemical	Scully R (1997)	1
SIRT6	2	EEF1A1	0	affinity chromatography technology	Simeoni F (2013)	1
8339	0	LRIF1	3	bioid	Lambert JP (2015)	1
RB1	2	TP53	0	affinity chromatography technology, pull down	Delston RB (2011), Sommer MH (1994)	2
MNAT1	0	MDM4	0	two hybrid	Woodsmith J (2012)	1
CDK2	0	SP1	0	enzymatic study	Fojas de Borja P (2001)	1
CDK7	0	GTF2H4	2	affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Varjosalo M (2013)	2
CDK2	0	RPA1	0	enzymatic study	Pan ZQ (1993)	1
RPA3	2	GTF2H3	2	affinity chromatography technology	Marechal A (2014)	1
RPA2	0	CDK7	0	affinity chromatography technology, biochemical	Marechal A (2014), Wan C (2015)	2
TP53	0	CCNH	3	far western blotting, affinity chromatography technology	Schneider E (1998), Schneider E (1998)	2
MNAT1	0	TRIM26	1	two hybrid	Woodsmith J (2012)	1
MDM4	0	RB1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Uchida C (2006), Uchida C (2006), Zhang H (2015), Zhang H (2015)	4
CDK2	0	EEF1A1	0	affinity chromatography technology	Neganova I (2011)	1
TP53	0	ESR1	0	pull down, affinity chromatography technology, affinity chromatography technology	Liu G (2000), Duong V (2007), Saxena R (2016)	3
CCNH	3	CDK2	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu X (1999), Higashi H (1996), Garrett S (2001), Lolli G (2004), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
CCNH	3	MCM7	5	affinity chromatography technology	Wang Y (2000)	1
MTA1	3	ESR1	0	affinity chromatography technology, pull down, pull down, pull down, pull down, pull down	Kumar R (2002), Kumar R (2002), Kumar R (2002), Mazumdar A (2001), Singh RR (2006), Mishra SK (2003)	6
5430	0	ERCC3	3	affinity chromatography technology	Fousteri M (2006)	1
SUPT5H	2	5430	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology	Kim JB (1999), Wada T (1998), Kang H (2011), Kang H (2011), Havugimana PC (2012), Yamaguchi Y (2002), Yamaguchi Y (1999), Yamaguchi Y (1999), Bennett CB (2008), Wan C (2015), Hein MY (2015)	11
GTF2H5	0	CCNH	3	affinity chromatography technology	Hein MY (2015)	1
RB1	2	MNAT1	0	pull down	Wu L (2001)	1
CDK7	0	TP53	0	enzymatic study, affinity chromatography technology, enzymatic study, pull down	Ko LJ (1997), Schneider E (1998), Lu H (1997), Lu H (1997)	4
SIRT6	2	MNAT1	0	affinity chromatography technology	Huttlin EL (2017)	1
5430	0	MCM7	5	affinity chromatography technology, biochemical	Kang H (2011), Yankulov K (1999)	2
TP53	0	ERCC2	4	pull down, far western blotting, pull down	Wang XW (1995), Leveillard T (1996), Leveillard T (1996)	3
CCNH	3	ESR1	0	affinity chromatography technology	Talukder AH (2003)	1
RPA3	2	RPA1	0	biochemical, x-ray crystallography, affinity chromatography technology, biochemical, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology	Bochkareva E (1998), Bochkareva E (2002), Gong Z (2011), Havugimana PC (2012), Du Y (2009), Wan C (2015), Hein MY (2015), Elia AE (2015)	8
BRCA1	7	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, biochemical, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2004), Ouchi T (1998), Dong Y (2003), Dong Y (2003), Chai YL (1999), Chai YL (1999), Zhang H (1998), Dong Y (2003), Chen Y (2006), Quaresima B (2006), Zhang H (1998), Zhang H (1998), Mark WY (2005), Jin S (2009), Jiang J (2011), Rasti M (2015), Rasti M (2015)	17
TP53	0	MNAT1	0	pull down, affinity chromatography technology	Ko LJ (1997), Ko LJ (1997)	2
EGLN3	0	RPA3	2	affinity chromatography technology	Rodriguez J (2016)	1
GTF2H2	0	CDK7	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vermeulen W (2000), Jeronimo C (2007), Varjosalo M (2013)	3
TRIM14	1	RPA1	0	bioid	Tan P (2017)	1
MDM4	0	USP2	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Allende-Vega N (2010), Allende-Vega N (2010), Wang CL (2014), Wang CL (2014), Wang CL (2014)	5
RPA3	2	MNAT1	0	affinity chromatography technology	Marechal A (2014)	1
CDK2	0	MCM7	5	affinity chromatography technology	Neganova I (2011)	1
TRIM34	1	TRIM5	4	two hybrid, two hybrid	Zhang F (2006), Woodsmith J (2012)	2
MNAT1	0	TRIML1	2	two hybrid	Woodsmith J (2012)	1
GTF2H3	2	7495	0	pull down	Jawhari A (2002)	1
USP2	0	TRIM21	0	two hybrid	Hayes SD (2012)	1
CCNH	3	5430	0	enzymatic study, biochemical, enzymatic study	Chen R (2004), Nekhai S (1997), Lolli G (2004)	3
GTF2H5	0	GTF2H4	2	affinity chromatography technology, affinity chromatography technology, pull down	Hein MY (2015), Huttlin EL (2017), Luo J (2015)	3
MNAT1	0	TRIM34	1	two hybrid	Woodsmith J (2012)	1
RPA2	0	EEF1A1	0	two hybrid, affinity chromatography technology	Stelzl U (2005), Marechal A (2014)	2
PCIF1	0	MNAT1	0	affinity chromatography technology	Hein MY (2015)	1
POU2F2	2	ESR1	0	pull down	Prefontaine GG (1999)	1
ESR1	0	5430	0	affinity chromatography technology, imaging technique, imaging technique, pull down	Ambrosino C (2010), Zhang H (2006), Zhang H (2006), Nalvarte I (2010)	4
MNAT1	0	SUPT5H	2	enzymatic study	Larochelle S (2006)	1
BRCA1	7	USP2	0	two hybrid, two hybrid	Woods NT (2012), Hayes SD (2012)	2
ERCC2	4	GTF2H2	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Coin F (1998), Coin F (1998), Vermeulen W (2000), Dubaele S (2003), Luo J (2015)	5
ERCC3	3	MNAT1	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Giglia-Mari G (2004), Jeronimo C (2007), Drapkin R (1996), Drapkin R (1996), Huttlin EL (2017), Luo J (2015), Luo J (2015)	7
GTF2H5	0	GTF2H3	2	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
CDK2	0	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study	Ruffner H (1999), Ruffner H (1999), Ruffner H (1999), Wang H (1997), Chen Y (1996)	5
CCNH	3	ERCC2	4	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Drapkin R (1996), Havugimana PC (2012), Huttlin EL (2015), Huttlin EL (2017)	4
BRCA1	7	ESR1	0	imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Zheng L (2001), Fan S (2001), Fan S (2001), Kawai H (2002), Fan S (2002), Fan S (2002), Nakuci E (2006), Wang C (2005), Wang C (2005), Dizin E (2010), Dizin E (2010), Ma Y (2010), Ma Y (2010), Fan S (2001), Ma YX (2005), Ma YX (2005), Ma YX (2005), Ma Y (2007), Ma Y (2007), Kawai H (2002), Jung YS (2014), Kawai H (2002), Kawai H (2002)	23
MNAT1	0	MCM7	5	two hybrid, pull down, affinity chromatography technology	Wang Y (2000), Wang Y (2000), Wang Y (2000)	3
USP2	0	TRIM34	1	two hybrid	Hayes SD (2012)	1
MNAT1	0	EEF1A1	0	two hybrid	Stelzl U (2005)	1
POU2F1	5	MNAT1	0	pull down, two hybrid	Inamoto S (1997), Inamoto S (1997)	2
TRIM31	0	MKRN3	2	two hybrid	Woodsmith J (2012)	1
RPA1	0	CDK7	0	affinity chromatography technology	Marechal A (2014)	1
MNAT1	0	TRIM5	4	two hybrid	Woodsmith J (2012)	1
RPA3	2	CCNH	3	affinity chromatography technology	Marechal A (2014)	1
MNAT1	0	TRIM39	0	two hybrid	Woodsmith J (2012)	1
SP1	0	POU2F1	5	two hybrid, pull down, pull down, pull down, affinity chromatography technology	Stroem AC (1996), Stroem AC (1996), Gunther M (2000), Lim K (2009), Lim K (2009)	5
RPA1	0	GTF2H3	2	affinity chromatography technology	Marechal A (2014)	1
GTF2H1	0	ESR1	0	enzymatic study, pull down	Chen D (2000), Chen D (2000)	2
LRIF1	3	ESR1	0	pull down	Li HJ (2007)	1
RPA2	0	RBM48	1	two hybrid	Stelzl U (2005)	1
CDK7	0	5430	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, biochemical, enzymatic study, enzymatic study, enzymatic study	Drapkin R (1996), Gegonne A (2008), Moisan A (2004), Pinhero R (2004), Ramanathan Y (2001), Larochelle S (2012), Larochelle S (2006), Nekhai S (1997), Pinhero R (2004), Rovnak J (2012), Lolli G (2004)	11
5430	0	CDK2	0	biochemical	Nekhai S (1997)	1
MKRN3	2	MDM4	0	two hybrid	Woodsmith J (2012)	1
RPA1	0	EEF1A1	0	affinity chromatography technology	Marechal A (2014)	1
8339	0	BRCA1	7	bioid	Lambert JP (2015)	1
MCM7	5	RPA1	0	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
GTF2H3	2	GTF2H4	2	pull down, biochemical, biochemical, affinity chromatography technology, pull down	Jawhari A (2002), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Luo J (2015)	5
GTF2H2	0	GTF2H1	0	affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid, biochemical, pull down	Vermeulen W (2000), Humbert S (1994), Humbert S (1994), Wang J (2011), Wan C (2015), Luo J (2015)	6
7495	0	GTF2H4	2	pull down, pull down	Jawhari A (2002), Jawhari A (2002)	2
MNAT1	0	LRIF1	3	two hybrid	Stelzl U (2005)	1
EEF1A1	0	5430	0	biochemical	Wan C (2015)	1
RPA2	0	MNAT1	0	affinity chromatography technology	Marechal A (2014)	1
GTF2H2	0	CCNH	3	affinity chromatography technology	Vermeulen W (2000)	1
GTF2H3	2	ERCC2	4	pull down	Chymkowitch P (2011)	1