PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
RASSF1	3	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SHC1	0	HSP90AA1	7	affinity chromatography technology	Brehme M (2009)	1
TP53	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Wang C (2003), Akakura S (2001), Peng Y (2001), Nagata Y (1999), Wang J (2011), Burch L (2004), Taipale M (2012), Fogeron ML (2013), Walerych D (2004)	9
SRC	2	GAB2	3	affinity chromatography technology	Zhao C (1999)	1
FBXO6	0	HSP90AB1	2	affinity chromatography technology	Liu B (2012)	1
CD44	1	SRC	2	affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Bourguignon LY (2001), Bourguignon LY (2001), Su YJ (2011), Zhu D (1998)	4
SH3KBP1	1	INPPL1	6	affinity chromatography technology	Havrylov S (2009)	1
MET	7	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
LATS2	1	HSP90AB1	2	affinity chromatography technology	Huntoon CJ (2010)	1
GAB1	3	MET	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schaeper U (2000), Fixman ED (1997), Fixman ED (1997)	3
GRB2	2	HSP90AA1	7	affinity chromatography technology	Brehme M (2009)	1
LRIG1	1	ERBB3	3	affinity chromatography technology	Gur G (2004)	1
SH3KBP1	1	RAF1	3	affinity chromatography technology	Sato S (2013)	1
HSP90AB1	2	SRC	2	affinity chromatography technology	Karras GI (2017)	1
RAF1	3	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K3	1	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CD44	1	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsatas D (2002), Wakahara K (2005), Wakahara K (2005), Perez A (2013)	4
RAF1	3	RANBP9	5	two hybrid, affinity chromatography technology, affinity chromatography technology	Johnson SE (2006), Atabakhsh E (2012), Atabakhsh E (2012)	3
TP53	0	RANBP9	5	two hybrid	Chen J (2008)	1
PTEN	24	CDH1	4	affinity chromatography technology	Choi BH (2014)	1
MET	7	MET	7	enzymatic study, enzymatic study	Breindel JL (2013), Smith BD (2015)	2
MAP2K5	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CTNNB1	30	SRC	2	affinity chromatography technology	Xi Y (2013)	1
TP53	0	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	CDK6	0	affinity chromatography technology, fluorescent resonance energy transfe	Varjosalo M (2013), Ivanov AA (2017)	2
HGF	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDH1	4	ERBB3	3	bioid	Guo Z (2014)	1
CD44	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	CCND2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Lin J (2001), Kehn K (2004), Kehn K (2004), Sweeney KJ (1997), Huttlin EL (2015), Huttlin EL (2017), Denicourt C (2008), Ivanov AA (2017)	8
HSP90AB1	2	HSPA4	3	biochemical, affinity chromatography technology	Wan C (2015), Reidy M (2018)	2
NF2	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KDELR2	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDH1	4	CRK	0	bioid	Guo Z (2014)	1
CRK	0	GAB1	3	affinity chromatography technology	Brehme M (2009)	1
ERBB3	3	PTEN	24	two hybrid	Yao Z (2017)	1
LGALS9	0	CTNNB1	30	affinity chromatography technology	Ewing RM (2007)	1
TERT	7	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDH1	4	PCBP1	2	bioid	Guo Z (2014)	1
GLIS2	2	RAF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	ERBB3	3	affinity chromatography technology	Liu X (2011)	1
PTEN	24	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBL	7	HSPA4	3	affinity chromatography technology	Valiya Veettil M (2011)	1
CDH1	4	NF2	1	bioid	Guo Z (2014)	1
STK11	2	STUB1	4	affinity chromatography technology	Gaude H (2012)	1
GLIS2	2	CTNNB1	30	two hybrid, affinity chromatography technology, pull down	Kim YS (2007), Kim YS (2007), Kim YS (2007)	3
GLIS2	2	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CD44	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CRK	0	SOCS1	1	pull down, two hybrid	De Sepulveda P (1999), Grossmann A (2015)	2
HSP90AA1	7	CDK4	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsutsumi S (2012), Wang H (2002), Taipale M (2012), Varjosalo M (2013), Huttlin EL (2015), Woodford MR (2016), Huttlin EL (2017)	7
MAP2K5	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PCBP1	2	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
LATS2	1	RASSF1	3	fluorescent resonance energy transfe, pull down, fluorescent resonance energy transfe	Mo XL (2015), Mo XL (2015), Ivanov AA (2017)	3
SH3KBP1	1	CRK	0	affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000)	2
CBLC	1	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SRC	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Olayioye MA (1999), Keely SJ (2000), Sato K (2000), Lee CW (2007), Jaganathan S (2011), Jaganathan S (2011), Lee IT (2010), Hitosugi T (2007), Chang CC (2012), Chang CC (2012), Tung WH (2011), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Yao Z (2017)	15
KDELR2	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CRK	0	GGA3	6	affinity chromatography technology	Parachoniak CA (2011)	1
CDK4	2	MYC	2	enzymatic study, two hybrid, fluorescent resonance energy transfe	Anders L (2011), Wang J (2011), Ivanov AA (2017)	3
HGF	1	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STUB1	4	TERT	7	pull down, affinity chromatography technology, affinity chromatography technology	Lee JH (2010), Lee JH (2010), Lee JH (2010)	3
MAP2K5	1	FZR1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	SPSB4	1	affinity chromatography technology	Wang D (2005)	1
KDELR2	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	CBLC	1	affinity chromatography technology	Takeshita K (2012)	1
RANBP9	5	RANBP10	0	affinity chromatography technology	Boldt K (2016)	1
CRK	0	SOS1	5	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Okada S (1996), Okada S (1996), Okada S (1996), Ingham RJ (1996), Brehme M (2009), Chen TC (2014)	6
HSP90AA1	7	FZR1	1	genetic interference	Srivas R (2016)	1
TERT	7	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STUB1	4	SRC	2	pull down, affinity chromatography technology, imaging technique, enzymatic study	Yang M (2011), Yang M (2011), Yang M (2011), Yang M (2011)	4
LRIG1	1	CBL	7	pull down	Gur G (2004)	1
HSP90AA1	7	STAT3	0	affinity chromatography technology	Sato N (2003)	1
EGFR	5	HSPA4	3	protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Deribe YL (2009), Deribe YL (2009), Citri A (2002), Tong J (2008), Kotlyar M (2015), Petschnigg J (2014)	6
ERBB3	3	SHC1	0	affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Jones RB (2006), Li J (2013), Hellyer NJ (2001)	5
CBLC	1	EGFR	5	affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, x-ray crystallography	Kim M (1999), Keane MM (1999), Keane MM (1999), Takeshita K (2012), Takeshita K (2012), Takeshita K (2012)	6
MET	7	SPSB3	1	affinity chromatography technology	Wang D (2005)	1
STK11	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDH1	4	GGA3	6	bioid	Guo Z (2014)	1
CHEK1	2	FZR1	1	genetic interference	Srivas R (2016)	1
HSP90AA1	7	MYC	2	affinity chromatography technology	Carystinos GD (2003)	1
PTEN	24	EGFR	5	affinity chromatography technology	Zheng J (2016)	1
CDH1	4	HSP90AB1	2	bioid	Guo Z (2014)	1
MET	7	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STAT3	0	CBL	7	two hybrid	Grossmann A (2015)	1
CDK6	0	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CRK	0	HSP90AB1	2	affinity chromatography technology	Brehme M (2009)	1
TP53	0	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EGFR	5	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ettenberg SA (1999), Tvorogov D (2002), Pennock S (2008), Umebayashi K (2008), Ng C (2008), Ng C (2008), Povlsen GK (2008), Khan EM (2008), Su X (2007), Shtiegman K (2007), Han W (2006), Visser GD (2005), Tsacoumangos A (2005), Prasad NK (2005), Gur G (2004), Kowanetz K (2004), Feshchenko EA (2004), Wu WJ (2003), Schmidt MH (2003), Bao J (2003), Rubin C (2003), Waterman H (1999), Bonaccorsi L (2007), Dey N (2011), Miraoui H (2010), Guo HB (2009), Tong J (2009), Tong J (2009), Sun Q (2010), Sanada F (2009), Rafiq K (2011), Ravid T (2004), Ravid T (2004), Duan L (2011), Duan L (2011), Haglund K (2005), Oksvold MP (2003), Oksvold MP (2003), Gui A (2012), Yang S (2006), de Melker AA (2004), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Raguz J (2007), de Melker AA (2004), Thien CB (2001), Kassenbrock CK (2004), Tarcic G (2009), Schroeder B (2012), Adachi S (2009), Shen F (2007), Mitsushima M (2006), Choi JH (2003), Burke P (2001), Tanaka S (1995), Meisner H (1995), Meisner H (1995), Kumar EA (2012), Tong J (2008), Dou H (2012), Levkowitz G (1999), Levkowitz G (1999), Bode AM (2009), Thomas C (2012), Meijer IM (2013), Chang CC (2012), Chang CC (2012), Smith CJ (2013), Gan Y (2010), Scott RP (2005), Fukazawa T (1996), Fukazawa T (1996), Fukazawa T (1996), Wang L (2013), Hong SY (2013), Sigismund S (2013), Sigismund S (2013), Sigismund S (2013), Meisner H (1997), Odintsova E (2013), Kondratov KA (2010), He Z (2014), Tong J (2014), Balaji K (2012), Kiuchi T (2014), Zhang B (2005), Waterman H (1999), Ha Thi HT (2015), Yao S (2015), Kortuem F (2015), Igloi Z (2015), Song F (2016), Song F (2016), Lin TY (2017), Conte A (2017)	96
CDH1	4	GAB1	3	bioid	Guo Z (2014)	1
HGF	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TERT	7	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBL	7	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017)	83
CHEK1	2	MET	7	genetic interference	Shen JP (2017)	1
FZR1	1	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK1	2	LATS2	1	enzymatic study, enzymatic study	Okada N (2011), Suzuki H (2013)	2
SRC	2	RANBP9	5	affinity chromatography technology, affinity chromatography technology	Dai H (2016), Dai H (2016)	2
FGFR4	6	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	SHC1	0	affinity chromatography technology	Liang Q (1998)	1
FZR1	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	RAF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	HGF	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Comoglio PM (1993), Comoglio PM (1993), Naldini L (1991), Goldoni S (2009), Ivanov AA (2017)	5
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
CDKN2B	0	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RAF1	3	CD44	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CD44	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK1	2	TP53	0	affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study, enzymatic study	Tian H (2002), Sengupta S (2004), Tian H (2002), Goudelock DM (2003), Shieh SY (2000)	5
STK11	2	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSP90AA1	7	HSPA4	3	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Kim TS (2006), Hidalgo-de-Quintana J (2008), Skarra DV (2011), Wan C (2015)	4
CDK4	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GAB2	3	MET	7	affinity chromatography technology	Schaeper U (2000)	1
CD44	1	STAT3	0	affinity chromatography technology	Su YJ (2011)	1
SOS1	5	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000)	2
EGFR	5	FBXO6	0	affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Liu B (2012)	2
STK11	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GRB2	2	SH3KBP1	1	pull down, pull down	Gout I (2000), Borinstein SC (2000)	2
CDH1	4	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Genda T (2000), Swaminathan G (2011), Shen Y (2008), Guo Z (2014)	4
CDK6	0	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSP90AA1	7	SPSB1	3	affinity chromatography technology	Taipale M (2012)	1
EGFR	5	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Citri A (2002), Yang S (2006), Shimamura T (2005), Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014)	8
RASSF1	3	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
LGALS9	0	MET	7	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RAF1	3	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	FZR1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GRB2	2	SOCS1	1	pull down	De Sepulveda P (1999)	1
EGFR	5	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Soubeyran P (2002), Szymkiewicz I (2002), Schmidt MH (2004), Schmidt MH (2003), Ronning SB (2011), Ronning SB (2011), Yang S (2006), Schmidt MH (2003)	8
TP53	0	STUB1	4	affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Muller P (2008), Stankiewicz M (2010), Tripathi V (2007), Tripathi V (2007), Esser C (2005), Lim JH (2011), Wang J (2011), Burch L (2004), Landre V (2013), Horikawa I (2014), Horikawa I (2014), Horikawa I (2014), Fraser JA (2015), Narayan V (2015), Yue X (2016), Parrales A (2016), Parrales A (2016)	17
ERBB3	3	CRK	0	unspecified method	Jones RB (2006)	1
MYC	2	RAF1	3	pull down, affinity chromatography technology, fluorescent resonance energy transfe	Alexandrov I (1997), Koch HB (2007), Ivanov AA (2017)	3
HSP90AA1	7	CHEK1	2	affinity chromatography technology, pull down, affinity chromatography technology	Ha K (2011), Arlander SJ (2006), Taipale M (2012)	3
TP53	0	SPSB1	3	affinity chromatography technology	Lunardi A (2010)	1
RASSF1	3	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	HGF	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	HSP90AB1	2	affinity chromatography technology	Fogeron ML (2013)	1
EGFR	5	RAF1	3	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
SHC1	0	HSP90AB1	2	affinity chromatography technology	Brehme M (2009)	1
CDH1	4	MET	7	affinity chromatography technology, affinity chromatography technology	Davies G (2001), Davies G (2001)	2
HGS	5	LRIG1	1	affinity chromatography technology, imaging technique	Oh YM (2014), Oh YM (2014)	2
CBLC	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	RAF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K3	1	CD44	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBLC	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBLC	1	CRK	0	pull down, two hybrid	Keane MM (1999), Grossmann A (2015)	2
INPPL1	6	MET	7	affinity chromatography technology	Sanada F (2009)	1
RAF1	3	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RAF1	3	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBL	7	EPHA2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2002), Chakraborty S (2012), Walker-Daniels J (2002), Walker-Daniels J (2002), Dutta D (2013)	5
CRK	0	INPPL1	6	affinity chromatography technology	Brehme M (2009)	1
NF2	1	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTEN	24	HSP90AB1	2	affinity chromatography technology, pull down	Maddika S (2011), Verrastro I (2015)	2
KDELR2	1	CD44	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ERBB3	3	HGS	5	affinity chromatography technology, affinity chromatography technology	Fosdahl AM (2017), Fosdahl AM (2017)	2
MAP2K5	1	CD44	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GNG12	0	MET	7	biochemical	Havugimana PC (2012)	1
EGFR	5	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Schulze WX (2006), Sakaguchi K (1998), Tong J (2009), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Burke P (2001), Katayama H (1999), Tong J (2008), Zhang L (1999), Levkowitz G (1999), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Foerster S (2013), Gotoh N (1994), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), Li J (2013), Prigent SA (1996), Prigent SA (1996), Grosse R (2000), Yao Z (2017), Wills MK (2014), Wills MK (2014), Kapoor GS (2010)	29
HSP90AA1	7	SPSB3	1	affinity chromatography technology	Taipale M (2012)	1
CDK4	2	CD44	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	PTEN	24	affinity chromatography technology, pull down, affinity chromatography technology	Song MS (2011), Song MS (2011), Choi BH (2014)	3
MAP2K3	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK6	0	MYC	2	enzymatic study, fluorescent resonance energy transfe	Anders L (2011), Ivanov AA (2017)	2
CHEK1	2	PTEN	24	genetic interference	Shen JP (2017)	1
CBLC	1	SRC	2	affinity chromatography technology, unspecified method, affinity chromatography technology, x-ray crystallography, pull down, enzymatic study	Ryan PE (2010), Takeshita K (2012), Takeshita K (2012), Takeshita K (2012), Kim M (2004), Kim M (2004)	6
FZR1	1	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	TERT	7	genetic interference, genetic interference	Xie L (2013), Xie L (2013)	2
LATS2	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KDELR2	1	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDH1	4	INPPL1	6	bioid	Guo Z (2014)	1
CDK4	2	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
MET	7	STUB1	4	affinity chromatography technology, affinity chromatography technology	Jang KW (2011), Jang KW (2011)	2
LATS2	1	CTNNB1	30	bioid, affinity chromatography technology, affinity chromatography technology, pull down	Couzens AL (2013), Li J (2013), Li J (2013), Li J (2013)	4
RASSF1	3	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K3	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	STUB1	4	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Paul I (2012), Paul I (2012), Paul I (2012), Huang H (2017)	4
NF2	1	EGFR	5	affinity chromatography technology, fluorescent resonance energy transfe	Guerrero PA (2015), Ivanov AA (2017)	2
PCBP1	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MET	7	DCN	0	affinity chromatography technology, pull down	Goldoni S (2009), Goldoni S (2009)	2
CBLC	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SOS1	5	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Qian X (2000), Foehr ED (2000), Park RK (1999), Chin H (1997), Wang Y (1999), Brehme M (2009), Brizzi MF (1996), Yu WM (2006), Klint P (1995)	9
MAP2K5	1	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STK11	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EGFR	5	MAP2K3	1	affinity chromatography technology	Tong J (2014)	1
CBLC	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EGFR	5	INPPL1	6	affinity chromatography technology, affinity chromatography technology	Pesesse X (2001), Sanada F (2009)	2
TP53	0	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLMN	2	MET	7	two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down	Grisendi S (2001), Grisendi S (2001), Grisendi S (2001), Grisendi S (2001), Grisendi S (2001), Grisendi S (2001)	6
GRB2	2	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Skolnik EY (1993), Skolnik EY (1993), Puil L (1994), Satoh T (1996), Fixman ED (1996), Fixman ED (1996), Fixman ED (1996), Ishihara H (1997), Fournier E (1999), Ravichandran KS (1994), Lamprecht R (2002), Park RK (1999), Sakaguchi K (2001), Park RK (1999), Park RK (1999), Hallak H (2001), Yokote K (1994), Saci A (2002), Zhang S (1999), Lazar DF (1994), VanderKuur J (1995), Kanai M (1997), Spivak-Kroizman T (1994), Giordano V (1997), Drobot L (2005), Erdreich-Epstein A (1997), Takahashi Y (1999), Barber DL (1997), Ahn SC (2003), Odai H (1995), Panchamoorthy G (1996), Panchamoorthy G (1996), Brehme M (2009), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Zhang L (1999), Brizzi MF (1996), Brizzi MF (1996), Liu BA (2012), Bisson N (2011), Fukazawa T (1996), Bisson N (2011), Umehara H (2002), Oksvold MP (2001), Oksvold MP (2001), Li J (2013), Li J (2013), Ueno H (1995), Prigent SA (1996), Wills MK (2014), Rausch O (1997), Ho JM (2002), Ho JM (2002), Yu WM (2006), Klint P (1995)	57
TP53	0	HSPA4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Muller P (2008), Fraser JA (2010), Sun Y (2007), Wang J (2011), Horikawa I (2014), Horikawa I (2014), Kishor A (2013)	7
RASSF1	3	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCND2	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STUB1	4	HSP90AA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, enzymatic study, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down	Zhang L (2007), Zhang M (2005), Tateishi Y (2004), Tateishi Y (2004), Connell P (2001), Ko HS (2009), Kumar P (2007), Kumar P (2007), Wang L (2011), Stankiewicz M (2010), Graf C (2010), Kundrat L (2010), Kundrat L (2010), Kundrat L (2010), Kundrat L (2010), Morishima Y (2008), Zhou P (2003), Zhang M (2008), Grelle G (2006), Kim SA (2005), Arndt V (2005), Muller P (2012), Burch L (2004), Burch L (2004), Jang KW (2011), Schuelke JP (2010), Wang Q (2012), Shimamoto S (2013), Shimamoto S (2013), Shimamoto S (2013), Gano JJ (2010), Skarra DV (2011), Yang SW (2013), Grelle G (2006), Grelle G (2006), Narayan V (2015)	36
INPPL1	6	HSP90AB1	2	affinity chromatography technology	Brehme M (2009)	1
GLIS2	2	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBL	7	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kassenbrock CK (2002), Rafiq K (2011), Rellahan BL (2003), Vantler M (2006), Shishido T (2000), Shishido T (2000), Song JJ (2010), Sanjay A (2006), Sanjay A (2006), Tanaka S (1995), Tanaka S (1995), Tanaka S (1995), Szymkiewicz I (2004), Hashimoto S (2006)	14
MAP2K5	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STUB1	4	HSPA4	3	pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down, pull down, enzymatic study, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ballinger CA (1999), Ballinger CA (1999), Ballinger CA (1999), Dai Q (2005), Tateishi Y (2004), Tateishi Y (2004), Ko HS (2009), Qian SB (2009), Kumar P (2007), Kumar P (2007), Wang L (2011), Wang L (2011), Wang L (2011), Graf C (2010), Kundrat L (2010), Matsumoto K (2011), Kundrat L (2010), Kundrat L (2010), Morishima Y (2008), Luo W (2010), Soss SE (2011), Zhou P (2003), Kalia LV (2011), Gao Y (2010), Gao Y (2010), Grelle G (2006), Rao SN (2010), Tetzlaff JE (2008), Kim SA (2005), Dai Q (2003), Zhang X (2011), Zhang X (2011), Muller P (2012), Jang KW (2011), Schuelke JP (2010), Jinwal UK (2012), Shimamoto S (2013), Shimamoto S (2013), Shimamoto S (2013), Mao RF (2013), Lee JS (2013), Lee JS (2013)	42
CASP3	0	CDH1	4	imaging technique	Chen TC (2014)	1
SOS1	5	EGFR	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Qian X (2000), Qian X (1998), Buday L (1994), Tong J (2009), Kurada BR (2009), Tong J (2008), Foerster S (2013), Tong J (2014), Kapoor GS (2010)	9
MET	7	SPSB1	3	affinity chromatography technology, affinity chromatography technology	Wang D (2005), Wang D (2005)	2
CRK	0	GRB2	2	pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Riordan SM (2000), Matsuda M (1996), Okada S (1996), Okada S (1996), Garcia-Guzman M (2000), Brehme M (2009)	6
CDH1	4	EPHA2	3	bioid	Guo Z (2014)	1
CRK	0	TP53	0	two hybrid	Grossmann A (2015)	1
TP53	0	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTEN	24	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDH1	4	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Davies G (2001), Kucerova D (2001), Oyama T (1994), Hazan RB (1997), Kinch MS (1995), Jiang MC (2002), Hazan RB (1998), Bonvini P (2001), Li Y (1998), Wendeler MW (2004), Shibata T (2003), Piedra J (2003), Oneyama C (2002), Navarro P (1993), Takahashi K (1997), Dobrosotskaya IY (2000), Dobrosotskaya IY (2000), Geng L (2000), Shibamoto S (1995), Rao RK (2002), Rao RK (2002), Huber AH (2001), Schmeiser K (1999), Pai R (2008), Tu LC (2007), Tu LC (2007), Smyth D (2012), Xue B (2005), Xue B (2005), Catimel B (2005), Huang Z (2012), Yan HX (2006), Yan HX (2006), Figueiredo J (2013), Ponce E (2014), Ponce E (2014), Ponce E (2014), Ribeiro AS (2013), Pinheiro H (2012), Geng F (2012), Lee HK (2007), Guo Z (2014)	42
PTEN	24	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	CDKN2B	0	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Rual JF (2005), Stelzl U (2005), Vinayagam A (2011), Xin X (2009), Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Ivanov AA (2017)	12
CTNNB1	30	HSP90AB1	2	affinity chromatography technology	Tian Q (2004)	1
TP53	0	STK11	2	affinity chromatography technology, fluorescent resonance energy transfe	Karuman P (2001), Ivanov AA (2017)	2
RASSF1	3	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK6	0	CD44	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SH3KBP1	1	MET	7	affinity chromatography technology	Petrelli A (2002)	1
NF2	1	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSP90AA1	7	CDK6	0	affinity chromatography technology	Taipale M (2012)	1
MAP2K5	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBL	7	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park RK (1999), Gesbert F (1998), Erdreich-Epstein A (1997), Wang Y (1999), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Brizzi MF (1996), Fukazawa T (1996)	9
RAF1	3	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GAB2	3	GAB1	3	two hybrid	van den Akker E (2004)	1
LRIG1	1	MET	7	affinity chromatography technology, affinity chromatography technology, imaging technique	Shattuck DL (2007), Oh YM (2014), Oh YM (2014)	3
MET	7	CTNNB1	30	affinity chromatography technology	Davies G (2001)	1
FBXO6	0	MET	7	affinity chromatography technology	Liu B (2012)	1
HGF	1	GLIS2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCND2	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBL	7	PTEN	24	affinity chromatography technology, affinity chromatography technology	Rodriguez S (2013), Rodriguez S (2013)	2
RASSF1	3	GLIS2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	TP53	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK1	2	FBXO6	0	affinity chromatography technology	Tu Y (2017)	1
LATS2	1	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HGS	5	SH3KBP1	1	affinity chromatography technology	Ronning SB (2011)	1
EGFR	5	CRK	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Schulze WX (2006), Hashimoto Y (1998), Hashimoto Y (1998), Katayama H (1999), Ota S (1998), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	9
NF2	1	HSPA4	3	affinity chromatography technology	Hauri S (2013)	1
MET	7	GGA3	6	affinity chromatography technology, imaging technique	Parachoniak CA (2011), Parachoniak CA (2011)	2
CBLC	1	SHC1	0	two hybrid	Vinayagam A (2011)	1
NF2	1	SOS1	5	affinity chromatography technology	Qian X (2000)	1
CDH1	4	EGFR	5	affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, bioid	Pece S (2000), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Li J (2013), Guo Z (2014)	6
KDELR2	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EPHA2	3	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FBXO6	0	PCBP1	2	affinity chromatography technology	Liu B (2012)	1
CBLC	1	TP53	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK1	2	SRC	2	genetic interference	Shen JP (2017)	1
EPHA2	3	GRB2	2	affinity chromatography technology, pull down	Pratt RL (2002), Pratt RL (2002)	2
NF2	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	FZR1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SRC	2	TP53	0	enzymatic study	Huang YF (2014)	1
CBLC	1	RAF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KDELR2	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	SPSB2	0	affinity chromatography technology	Wang D (2005)	1
RASSF1	3	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EGFR	5	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Yuan ZL (2004), Olayioye MA (1999), Lo HW (2005), Lo HW (2005), Crovello CS (1998), Jaganathan S (2011), Jaganathan S (2011), Andl CD (2004), Lo HW (2010), Foerster S (2013), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), de la Iglesia N (2008), Fan QW (2013), Fan QW (2013)	18
CBLC	1	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CASP3	0	MET	7	imaging technique	Chen TC (2014)	1
SH3KBP1	1	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000), Petrelli A (2002), Soubeyran P (2002), Soubeyran P (2002), Szymkiewicz I (2002), Borinstein SC (2000), Schmidt MH (2006), Schmidt MH (2004), Schmidt MH (2004), Verdier F (2002), Verdier F (2002), Feshchenko EA (2004), Chandra V (2010), Niiro H (2012), Feng L (2011), Havrylov S (2009), Zhang J (2009), Zhang J (2009), Ababou A (2009), Le Bras S (2007), Jozic D (2005), Kowanetz K (2004), Kowanetz K (2003), Kowanetz K (2003), Tibaldi EV (2003), Tibaldi EV (2003), Take H (2000), Take H (2000), Schroeder B (2012), Schroeder B (2012), Peruzzi G (2007), Selbach M (2006), Sato S (2013), Taipale M (2014), Taipale M (2014), Diesenberg K (2015), Petrelli A (2002), Huttlin EL (2017)	39
GLIS2	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ERBB3	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Li J (2013)	3
CDK6	0	CCND2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Lin J (2001), Sweeney KJ (1997), Varjosalo M (2013), Ivanov AA (2017)	4
SHC1	0	EPHA2	3	affinity chromatography technology, pull down	Pratt RL (2002), Pratt RL (2002)	2
SHC1	0	GAB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Boudot C (2002), Lynch DK (2002), van den Akker E (2004)	3
KDELR2	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RAF1	3	HSPA4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhu J (2005), Zhu J (2005), Zhu J (2005), da Rocha Dias S (2005)	4
LATS2	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK6	0	CTNNB1	30	imaging technique	Chen TC (2014)	1
ERBB3	3	HSP90AB1	2	affinity chromatography technology	Li J (2013)	1
EGFR	5	EPHA2	3	affinity chromatography technology	Tong J (2014)	1
MET	7	HSPA4	3	affinity chromatography technology	Jang KW (2011)	1
TP53	0	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDH1	4	SH3KBP1	1	bioid	Guo Z (2014)	1
SRC	2	MET	7	affinity chromatography technology	Rahimi N (1998)	1
RAF1	3	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SRC	2	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Narita T (2005), Schroeder B (2012)	2
PTEN	24	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSP90AA1	7	TERT	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Haendeler J (2003), Kawauchi K (2005), Holt SE (1999), Lee JH (2010), Lee JH (2010), Forsythe HL (2001)	6
CBL	7	INPPL1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vandenbroere I (2003), Prasad NK (2005), De Schutter J (2009), De Schutter J (2009), Brehme M (2009)	5
MET	7	CD44	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	SOCS1	1	affinity chromatography technology, pull down, affinity chromatography technology	Calabrese V (2009), Calabrese V (2009), Calabrese V (2009)	3
CBLC	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SRC	2	ERBB3	3	unspecified method	Jones RB (2006)	1
CBL	7	SOS1	5	affinity chromatography technology	Wang Y (1999)	1
HGF	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
LRIG1	1	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Laederich MB (2004), Gur G (2004), Stutz MA (2008)	3
MET	7	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SCGB1D1	1	MET	7	affinity chromatography technology	Huttlin EL (2017)	1
PTPRO	3	MET	7	affinity chromatography technology	Yadav L (2017)	1
HGF	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GAB1	3	SHC1	0	affinity chromatography technology, far western blotting, affinity chromatography technology	Ingham RJ (1998), Ingham RJ (1998), van den Akker E (2004)	3
NF2	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	PTEN	24	genetic interference	Shen JP (2017)	1
SHC1	0	INPPL1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wisniewski D (1999), Wisniewski D (1999), Pesesse X (2001), Habib T (1998), Brehme M (2009), Brehme M (2009)	6
RASSF1	3	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
DCN	0	EGFR	5	two hybrid, pull down, pull down	Santra M (2002), Santra M (2002), Iozzo RV (1999)	3
CBLC	1	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SHC1	0	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009), Ota S (1998), Larsson H (1999)	4
MAP2K5	1	GLIS2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SRC	2	GRB2	2	affinity chromatography technology, affinity chromatography technology	Wan KF (2003), Saci A (2002)	2
HGS	5	NF2	1	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid	Gutmann DH (2001), Scoles DR (2000), Scoles DR (2000), Scoles DR (2000), Scoles DR (2000), Sun CX (2002), Scoles DR (2002)	7
HSP90AA1	7	EPHA2	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Taipale M (2012)	2
CDK6	0	CDKN2B	0	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, two hybrid, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, fluorescent resonance energy transfe	Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013), Rolland T (2014), Huttlin EL (2015), Mo XL (2015), Huttlin EL (2017), Ivanov AA (2017)	8
NF2	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KDELR2	1	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	CRK	0	affinity chromatography technology	Oh YM (2014)	1
FZR1	1	TP53	0	enzymatic study	Gmachl M (2000)	1
HSP90AB1	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Cheng MB (2010), Gano JJ (2010), Skarra DV (2011), Kristensen AR (2012), Taipale M (2014), Taipale M (2014), Wan C (2015), Hein MY (2015)	8
MYC	2	TP53	0	affinity chromatography technology, fluorescent resonance energy transfe	Agrawal P (2010), Ivanov AA (2017)	2
RAF1	3	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	PCBP1	2	affinity chromatography technology	Fogeron ML (2013)	1
EGFR	5	HGS	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Umebayashi K (2008), Morino C (2004), Meijer IM (2013), Sun Y (2013), Ali N (2013), Tan X (2015)	6
HGS	5	MET	7	affinity chromatography technology	Oh YM (2014)	1
MET	7	STAT3	0	affinity chromatography technology	Boccaccio C (1998)	1
HSP90AA1	7	ERBB3	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Li J (2013)	2
MYC	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CRK	0	GAB2	3	affinity chromatography technology	Brehme M (2009)	1
MYC	2	SH3KBP1	1	genetic interference	Toyoshima M (2012)	1
CDK4	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBLC	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	MAP2K3	1	genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Toyoshima M (2012), Ivanov AA (2017), Ivanov AA (2017), Ivanov AA (2017)	4
PTEN	24	STUB1	4	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ahmed SF (2012), Ahmed SF (2012), Ahmed SF (2012), Yuan L (2015)	4
MET	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Jang KW (2011), Prince TL (2015)	2
RAF1	3	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CTNNB1	30	CBL	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Chitalia V (2013), Chitalia V (2013), Chitalia V (2013), Shivanna S (2015)	4
STK11	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GRB2	2	GAB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Million RP (2004), Lynch DK (2002), Zhao C (1999), Zhao C (1999), Bandyopadhyay S (2010), Brehme M (2009), Bisson N (2011), Rolland T (2014), Huttlin EL (2017), Yu WM (2006), Yu WM (2006)	11
GRB2	2	HSP90AB1	2	affinity chromatography technology	Brehme M (2009)	1
FZR1	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PCBP1	2	STUB1	4	affinity chromatography technology	Zhang MP (2017)	1
LATS2	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	PCBP1	2	affinity chromatography technology	Koch HB (2007)	1
CD44	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K3	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSP90AA1	7	SRC	2	affinity chromatography technology, affinity chromatography technology	Hutchison KA (1992), Tsutsumi S (2012)	2
RASSF1	3	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RANBP10	0	MET	7	affinity chromatography technology, pull down	Wang D (2004), Wang D (2004)	2
HGF	1	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KDELR2	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	SOCS1	1	affinity chromatography technology, affinity chromatography technology, pull down	Gui Y (2015), Gui Y (2015), Gui Y (2015)	3
TERT	7	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FGFR4	6	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDH1	4	HSP90AA1	7	affinity chromatography technology	Catimel B (2005)	1
CDH1	4	CBL	7	bioid	Guo Z (2014)	1
EGFR	5	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	6
HGF	1	RAF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBL	7	MET	7	enzymatic study, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, pull down, far western blotting, imaging technique	Petrelli A (2002), Ng C (2008), Ng C (2008), Kong-Beltran M (2006), Kong-Beltran M (2006), Peschard P (2004), Peschard P (2004), Deheuninck J (2009), Goldoni S (2009), Hill KS (2011), Sun Q (2011), Sun Q (2011), Sun Q (2011), Peschard P (2004), Chen TC (2014)	15
CCND2	2	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBLC	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	CD44	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RAF1	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stancato LF (1993), Dogan T (2008), Mollapour M (2010), Du J (2006), Maloney A (2007), Fiskus W (2007), Giommarelli C (2010), Arlander SJ (2006), ONeill E (2004), Taipale M (2012), Zhu J (2005), Schneider C (1996), Mollapour M (2014), Atabakhsh E (2012), Mitra S (2016)	15
TERT	7	HSPA4	3	pull down	Forsythe HL (2001)	1
HSP90AB1	2	MET	7	affinity chromatography technology	Prince TL (2015)	1
CDKN2B	0	CD44	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
LATS2	1	SRC	2	affinity chromatography technology	Si Y (2017)	1
EGFR	5	STUB1	4	protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Deribe YL (2009), Wang T (2014), Wang T (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Chung C (2016), Chung C (2016)	8
MAP2K3	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FBXO6	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Liu B (2012), Taipale M (2012)	2
GLIS2	2	CBLC	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HGF	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RAF1	3	STUB1	4	affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study	Dogan T (2008), Dogan T (2008), Alberti S (2004), Westhoff B (2005), Dreiseidler M (2012)	5
CDK6	0	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EGFR	5	CTNNB1	30	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hazan RB (1998), Schroeder JA (2002), Takahashi K (1997), Li J (2013)	4
HGF	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EGFR	5	GAB1	3	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, enzymatic study, affinity chromatography technology	Kameda H (2001), Tong J (2008), Kotlyar M (2015), Petschnigg J (2014), Lehr S (1999), Mueller KL (2012)	6
SHC1	0	SRC	2	pull down	Schueller AC (2008)	1
SRC	2	RAF1	3	affinity chromatography technology, pull down	Cleghon V (1994), Cleghon V (1994)	2
RAF1	3	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FGFR4	6	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RAF1	3	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK6	0	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	KDELR2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCND2	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STK11	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nony P (2003), Brajenovic M (2004), Gaude H (2012), Taipale M (2012), Huttlin EL (2017)	5
CD44	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTEN	24	HSP90AA1	7	affinity chromatography technology, genetic interference	Maddika S (2011), Shen JP (2017)	2
CRK	0	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, two hybrid	Gesbert F (1998), Husson H (1997), Ingham RJ (1996), Ingham RJ (1996), Delehanty LL (2003), Garcia-Guzman M (2000), Garcia-Guzman M (2000), Barber DL (1997), Buday L (1996), Sawasdikosol S (1996), Sawasdikosol S (1996), Thien CB (1997), van Leeuwen JE (1999), Ribon V (1996), Lottin-Divoux S (2006), Reedquist KA (1996), Brehme M (2009), Brehme M (2009), Ota S (1998), Peterson ME (2008), Liu BA (2012), Fukazawa T (1996), Umehara H (2002), Grossmann A (2015)	24
FZR1	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KDELR2	1	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CASP3	0	CTNNB1	30	imaging technique	Chen TC (2014)	1
RASSF1	3	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSP90AB1	2	STUB1	4	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
MET	7	PTEN	24	genetic interference	Shen JP (2017)	1
CCND2	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBLC	1	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
INPPL1	6	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009), Brehme M (2009), Bisson N (2011)	4
PTEN	24	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Freeman DJ (2003), Freeman DJ (2003), Zhou M (2003), Zhou M (2003), Hong SW (2013), Li Y (2008)	6
KDELR2	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SRC	2	STAT3	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down	Cao X (1996), Cao X (1996), Yin N (2004), Yin N (2004), Jaganathan S (2011), Jaganathan S (2011), Gray MJ (2005), Schreiner SJ (2002)	8
STK11	2	HSP90AB1	2	affinity chromatography technology	Huttlin EL (2017)	1
FZR1	1	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	EGFR	5	genetic interference, genetic interference	Xie L (2013), Ye H (2016)	2
PTEN	24	SOCS1	1	genetic interference	Vizeacoumar FJ (2013)	1
CEACAM21	1	SRC	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MET	7	RANBP9	5	two hybrid, pull down, affinity chromatography technology	Wang D (2002), Wang D (2002), Wang D (2002)	3
KDELR2	1	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EGFR	5	SOCS1	1	affinity chromatography technology	Xia L (2002)	1
GRB2	2	GAB1	3	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, far western blotting, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Oneyama C (2002), Lewitzky M (2001), Lewitzky M (2001), Lewitzky M (2001), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Bandyopadhyay S (2010), Ingham RJ (1998), Brehme M (2009), Fixman ED (1997), Bisson N (2011), Huttlin EL (2017), Kapoor GS (2010), Lehr S (1999)	15
MAP2K5	1	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	LATS2	1	x-ray crystallography, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology	Li Y (2015), Yin F (2013), Ivanov AA (2017), Zhu C (2018)	4
GRB2	2	SOS1	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Liu SK (1998), Oneyama C (2002), Puil L (1994), Robinson A (1996), Li N (1993), Wong A (2002), Wong A (2002), Reif K (1994), DAngelo G (1999), Nel AE (1995), Pandey P (1995), Buday L (1994), Tong XK (2000), Park RK (1999), Okada S (1996), Okada S (1996), Okada S (1996), Germani A (1999), Park RK (1999), Chin H (1997), Saci A (2002), Sastry L (1997), Spivak-Kroizman T (1994), Ingham RJ (1996), Wang Y (1999), Chu J (1998), Brehme M (2009), Houtman JC (2006), Lao DH (2006), Bisson N (2011), Wang J (2011), Ng MY (2017), Huttlin EL (2017), Kapoor GS (2010), Saito T (2004), Klint P (1995)	37
MET	7	GRB2	2	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Ponzetto C (1996), Liang Q (1998), Goldoni S (2009), Hill KS (2011)	4
PTEN	24	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Li A (2010), Li A (2010)	2
MAP2K5	1	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EPHA2	3	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PCBP1	2	MET	7	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CD44	1	NF2	1	affinity chromatography technology, unspecified method, fluorescent resonance energy transfe	Tang X (2007), Mori T (2014), Ivanov AA (2017)	3
CDK6	0	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSP90AA1	7	MAP2K5	1	affinity chromatography technology	Taipale M (2012)	1
CEACAM21	1	MET	7	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGFR	5	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marques MM (1999), Li J (2013), Li J (2013), Sharif A (2009)	4
MET	7	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GRB2	2	HGS	5	affinity chromatography technology	Bisson N (2011)	1
MET	7	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HGF	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RAF1	3	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HGF	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CRK	0	SRC	2	affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Garcia-Guzman M (2000)	2
GLIS2	2	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	SOS1	5	affinity chromatography technology	Liang Q (1998)	1
EGFR	5	MET	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li J (2013), Li L (2015), Liu X (2011)	3