Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications
MDM2	4193	CHEMBL35482	CHEMBL35482		NCI	15385570
MDM2	4193	NUTLIN-2	CHEMBL407632		DrugBank	17139284, 17016423

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
MDM2	rs1470383	A	Platinum compounds	efficacy	no	Patients were treated with cisplatin or carboplatin in combination with a third-generation drug (gemcitabine, paclitaxel, pemetrexed or vinorelbine). No significant association with overall response rate (ORR), overall survival (OS) or progression-free survival (PFS) was found for this SNP. Please note that alleles have been complemented to the plus chromosomal strand.	Allele A is not associated with response to Platinum compounds in people with Carcinoma, Non-Small-Cell Lung as compared to allele G.	29662106	1449752415