PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
TP53	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Wang C (2003), Akakura S (2001), Peng Y (2001), Nagata Y (1999), Wang J (2011), Burch L (2004), Taipale M (2012), Fogeron ML (2013), Walerych D (2004)	9
NXF1	0	BAG4	2	affinity chromatography technology	Castello A (2012)	1
BAG3	4	UBXN6	1	affinity chromatography technology	Chen Y (2013)	1
PINK1	2	TRAF6	0	affinity chromatography technology, enzymatic study	Lee HJ (2012), Murata H (2013)	2
UHRF2	1	TP53	0	far western blotting, affinity chromatography technology, affinity chromatography technology, pull down	Mori T (2011), Mori T (2011), Mori T (2011), Mori T (2011)	4
MCL1	1	BAD	1	two hybrid, unspecified method, pull down	Bae J (2001), Chen L (2005), Bae J (2001)	3
TP53	0	BAK1	0	affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Leu JI (2004), Leu JI (2004), Leu JI (2004), Gogada R (2011), Holloway A (2014), Zhang X (2016)	6
MYC	2	GSK3B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Gregory MA (2003), Gregory MA (2003), Arnold HK (2009), Zhou Z (2014)	4
FBXW11	2	BAG4	2	affinity chromatography technology	Low TY (2014)	1
UNK	3	USP9X	15	biochemical, affinity chromatography technology	Havugimana PC (2012), Murn J (2015)	2
HSP90AA1	7	SKP1	0	pull down	Zhang M (2008)	1
TRAF6	0	HSPA4	3	affinity chromatography technology, enzymatic study, affinity chromatography technology	Chen H (2006), Pridgeon JW (2004), Chen H (2006)	3
HSPA1A	0	HSPA8	4	biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012)	2
FBXW11	2	BCL2L11	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dehan E (2009), Kim TY (2014), Huttlin EL (2015), Huttlin EL (2017)	4
BCL2L1	0	PMAIP1	0	unspecified method, affinity chromatography technology, unspecified method	Chen L (2005), Oda E (2000), Kuwana T (2005)	3
MCL1	1	PRKN	1	affinity chromatography technology, affinity chromatography technology	Hollville E (2014), Hollville E (2014)	2
MYC	2	CUL1	7	affinity chromatography technology	von der Lehr N (2003)	1
MCL1	1	PRKAG1	1	affinity chromatography technology	Huttlin EL (2015)	1
AGO2	10	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Fabian MR (2009), Maniataki E (2005)	2
TRAF6	0	TP53	0	enzymatic study, affinity chromatography technology	Zhang X (2016), Zhang X (2016)	2
BAD	1	BCL2L1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, pull down	Chen L (2005), Jin Z (2005), Jin Z (2005), Strobel T (1998), Zhang H (2002), Ayllon V (2002), Komatsu K (2000), Yang E (1995), Yang E (1995), Petros AM (2000), Chattopadhyay A (2001), Iwahashi H (1997), Komatsu K (2000), Wang J (2008), Wang J (2008), Polzien L (2009), Wang J (2011), Kuwana T (2005), Zha J (1997), Zha J (1997), Zha J (1997), Rolland T (2014), Jin L (2009), Certo M (2006), Craik AC (2010), Craik AC (2010), Huttlin EL (2015), Chen TC (2014), Stegh AH (2010), Huttlin EL (2017), Schuermann A (2000)	31
MCL1	1	PRKAB1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TP53	0	BAX	3	imaging technique, affinity chromatography technology, pull down	Chen TC (2014), Kim EM (2014), Kim EM (2014)	3
CAV1	0	MAPK1	1	affinity chromatography technology	Hua H (2003)	1
BAG4	2	HSPA8	4	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Miki K (2002), Miki K (2002), Taipale M (2014), Taipale M (2014)	4
FBXW7	2	MCL1	1	enzymatic study, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Min SH (2012), Tong J (2017), Tong J (2017), Ye M (2017), Tong J (2017)	5
GSK3B	1	MCL1	1	affinity chromatography technology, enzymatic study	Ding Q (2007), Ding Q (2007)	2
PRKAA1	2	HSPA4	3	affinity chromatography technology	Al-Hakim AK (2005)	1
PRKAA1	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Al-Hakim AK (2005), Taipale M (2012), Varjosalo M (2013)	3
BCL2L1	0	BECN1	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liang XH (1998), Wang J (2008), Wang J (2008), Tang Y (2012), Noble CG (2008), Noble CG (2008), Pimkina J (2009), Pimkina J (2009), Zalckvar E (2009), Luo S (2010)	10
HSP90AA1	7	LYN	2	affinity chromatography technology	Taipale M (2012)	1
FBXW7	2	MYC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study	Thompson BJ (2007), Welcker M (2004), Welcker M (2004), Yada M (2004), Yada M (2004), Yada M (2004), Koch HB (2007), Kim BY (2010), Cho HJ (2010), Popov N (2007), Fujii M (2006), Yumimoto K (2012), Diefenbacher ME (2015), Kourtis N (2015), Kourtis N (2015), Li J (2017), Wang Y (2017), Reiterer V (2017), Chandra S (2013), Chandra S (2013), Chandra S (2013), Chandra S (2013)	22
BCL2L1	0	PINK1	2	affinity chromatography technology	Hollville E (2014)	1
GSK3B	1	UBXN6	1	two hybrid	Vinayagam A (2011)	1
BCL2L1	0	BIK	0	two hybrid, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, unspecified method	Rual JF (2005), Chen L (2005), Chen L (2005), Gillissen B (2003), Gillissen B (2003), Jiang A (2001), Kuwana T (2005), Certo M (2006)	8
BAD	1	BAX	3	affinity chromatography technology	Flores-Delgado G (2007)	1
CUL1	7	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Suzuki H (2000), Cenciarelli C (1999), Sowa ME (2009), Megumi Y (2005), Davis M (2002), Kawakami T (2001), Read MA (2000), Suzuki H (1999), Kumar KG (2007), Schweitzer K (2007), Chua YS (2011), Winston JT (1999), Winston JT (1999), Peschiaroli A (2010), Latres E (1999), Latres E (1999), Yoshida Y (2007), Bennett EJ (2010), Cui W (2012), Dehan E (2009), Busino L (2003), Chung FZ (2014), Chen ZW (2015), Kim TY (2014), Read MA (2000), Coyaud E (2015), Low TY (2014), Coyaud E (2015), He N (2005), Huttlin EL (2017), Kuang P (2016), Reitsma JM (2017), Reitsma JM (2017)	34
HSP90AA1	7	MCL1	1	genetic interference	Srivas R (2016)	1
BAX	3	CASP3	0	biochemical	Chandra D (2004)	1
PRKN	1	VDAC1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Okatsu K (2012), Sun Y (2012), Sun Y (2012), Sarraf SA (2013), Ham SJ (2016), Ham SJ (2016)	6
PRKN	1	CUL1	7	affinity chromatography technology, pull down, affinity chromatography technology	Staropoli JF (2003), Staropoli JF (2003), Gong Y (2014)	3
BCL2L1	0	HRK	0	fluorescent resonance energy transfe, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, unspecified method	Whitfield J (2003), Inohara N (1997), Inohara N (1997), Imaizumi K (1999), Imaizumi K (1999), Kuwana T (2005), Certo M (2006)	7
MYC	2	MCL1	1	genetic interference	Toyoshima M (2012)	1
HSP90AA1	7	GSK3A	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Taipale M (2012)	2
BECN1	2	TRAF6	0	affinity chromatography technology, enzymatic study	Shi CS (2010), Shi CS (2010)	2
MCL1	1	TRAF6	0	affinity chromatography technology, pull down	Choi YB (2014), Choi YB (2014)	2
HSPA4	3	RANBP6	5	biochemical	Kristensen AR (2012)	1
PIN1	0	TP53	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down	Wulf GM (2002), Wulf GM (2002), Zacchi P (2002), Zacchi P (2002), Vinayagam A (2011), Mantovani F (2007)	6
UHRF2	1	BCL2L1	0	far western blotting	Mori T (2011)	1
UHRF2	1	PIN1	0	affinity chromatography technology	Lai M (2016)	1
HSP90AA1	7	MYC	2	affinity chromatography technology	Carystinos GD (2003)	1
LYN	2	TP53	0	affinity chromatography technology, affinity chromatography technology	Ren X (2003), Ren X (2003)	2
PRKAB2	0	PRKAG1	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Cheung PC (2000), Cheung PC (2000), Behrends C (2010), Behrends C (2010), Moreno D (2009), Wang J (2011), Corominas R (2014), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	10
MCL1	1	BCL2L1	0	affinity chromatography technology	Bae J (2000)	1
BAG3	4	VDAC1	2	affinity chromatography technology	Chen Y (2013)	1
CASP3	0	FBXW11	2	affinity chromatography technology	Tan M (2006)	1
CAV1	0	ATG12	1	affinity chromatography technology, affinity chromatography technology	Chen ZH (2014), Chen ZH (2014)	2
GSK3A	1	BCL2L1	0	enzymatic study	Wang J (2012)	1
FBXW11	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Suzuki H (2000), Sowa ME (2009), Fuchs SY (1999), Tan P (1999), Bennett EJ (2010), Cui W (2012), Dehan E (2009), Busino L (2003), DAnnibale S (2014), Kim TY (2014), Coyaud E (2015), Low TY (2014), Chen TC (2014), Reitsma JM (2017)	14
FBXW7	2	GSK3B	1	affinity chromatography technology	Kwon YW (2012)	1
NXF1	0	MCL1	1	affinity chromatography technology	Castello A (2012)	1
HSPA1A	0	BECN1	2	affinity chromatography technology, affinity chromatography technology	Yang Y (2013), Yang Y (2013)	2
MYC	2	BOK	1	genetic interference	Toyoshima M (2012)	1
TRIM11	1	PRKAB2	0	affinity chromatography technology	Huttlin EL (2017)	1
PRKN	1	BECN1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Choubey V (2014), Lonskaya I (2014), Lonskaya I (2014), Lonskaya I (2014)	4
BID	1	BAK1	0	unspecified method	Holloway A (2014)	1
MCL1	1	FBXW11	2	affinity chromatography technology, affinity chromatography technology, unspecified method	Ding Q (2007), Ding Q (2007), Ding Q (2007)	3
CAV1	0	UBXN6	1	affinity chromatography technology, imaging technique	Kirchner P (2013), Kirchner P (2013)	2
BTRC	1	SKP1	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Suzuki H (2000), Strack P (2000), Margottin F (1998), Cenciarelli C (1999), Cenciarelli C (1999), Cenciarelli C (1999), Watanabe N (2004), Wu G (2003), Kawakami T (2001), Hattori K (1999), Hattori K (1999), Hattori K (1999), Kitagawa M (1999), Hart M (1999), Su Y (2008), Banerjee S (2010), Winston JT (1999), Winston JT (1999), Estrabaud E (2007), Latres E (1999), Latres E (1999), Liu J (2004), Lievens S (2009), Yoshida Y (2007), Yoshida Y (2007), Busino L (2012), Li T (2005), da Silva Almeida AC (2013), Sahasrabuddhe AA (2014), Choi BH (2014), Chong RA (2014), Kim TY (2014), Coyaud E (2015), Deng W (2015), Coyaud E (2015), Liu YQ (2015), He N (2005), Kuchay S (2017), Hauri S (2016)	40
MCL1	1	HSPA4	3	affinity chromatography technology, affinity chromatography technology	Bewley MA (2011), Stankiewicz AR (2009)	2
MAPK1	1	BCL2L11	4	affinity chromatography technology, affinity chromatography technology	He C (2014), He C (2014)	2
HSP90AA1	7	HSPA4	3	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Kim TS (2006), Hidalgo-de-Quintana J (2008), Skarra DV (2011), Wan C (2015)	4
PRKN	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Imai Y (2003), Taipale M (2012), Zanon A (2013)	3
GSK3B	1	PMAIP1	0	two hybrid	Vinayagam A (2011)	1
UBXN6	1	HSPA1A	0	affinity chromatography technology	Haines DS (2012)	1
MYC	2	PIN1	0	affinity chromatography technology, affinity chromatography technology	Arnold HK (2009), Yeh E (2004)	2
UNK	3	HUWE1	22	affinity chromatography technology	Murn J (2015)	1
NXF1	0	CAV1	0	affinity chromatography technology	Castello A (2012)	1
BID	1	BAX	3	imaging technique	Chen TC (2014)	1
C5AR2	1	MCL1	1	affinity chromatography technology	Huttlin EL (2017)	1
MCL1	1	HSPA8	4	affinity chromatography technology	Stankiewicz AR (2009)	1
CASP3	0	MCL1	1	enzymatic study	Weng C (2005)	1
MCL1	1	SERPINB7	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MCL1	1	SKP1	0	affinity chromatography technology, affinity chromatography technology	Ye M (2017), Feng C (2017)	2
BECN1	2	TP53	0	affinity chromatography technology	Verma N (2017)	1
BAK1	0	BAX	3	affinity chromatography technology, affinity chromatography technology	Sundararajan R (2001), Gogada R (2011)	2
MCL1	1	PINK1	2	affinity chromatography technology	Hollville E (2014)	1
FBXW11	2	TP53	0	affinity chromatography technology	Low TY (2014)	1
UHRF2	1	MCL1	1	far western blotting	Mori T (2011)	1
BAG3	4	BMF	0	affinity chromatography technology	Chen Y (2013)	1
UHRF2	1	SKP1	0	far western blotting	Mori T (2011)	1
CUL1	7	NXF1	0	affinity chromatography technology	Bennett EJ (2010)	1
HUWE1	22	PCNA	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Markkanen E (2011), Thompson JW (2014), Choe KN (2016), Choe KN (2016), Choe KN (2016), Choe KN (2016)	6
HUWE1	22	HSPA4	3	affinity chromatography technology, affinity chromatography technology	Bewley MA (2011), Thompson JW (2014)	2
BAG3	4	BAX	3	affinity chromatography technology	Chen Y (2013)	1
CAV1	0	MCL1	1	affinity chromatography technology, affinity chromatography technology	Chunhacha P (2012), Chunhacha P (2012)	2
HSP90AA1	7	BTRC	1	affinity chromatography technology	Taipale M (2012)	1
BAG3	4	BID	1	affinity chromatography technology, affinity chromatography technology	Chen Y (2013), Chen Y (2013)	2
LYN	2	MCL1	1	affinity chromatography technology	Zhu J (2013)	1
MCL1	1	ASPRV1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGLN3	0	SKP1	0	affinity chromatography technology	Rodriguez J (2016)	1
EDEM2	3	MCL1	1	affinity chromatography technology	Huttlin EL (2017)	1
VDAC1	2	BCL2L11	4	affinity chromatography technology	Sugiyama T (2002)	1
HUWE1	22	HSP90AA1	7	affinity chromatography technology	Thompson JW (2014)	1
CASP3	0	BTRC	1	affinity chromatography technology	Tan M (2006)	1
NXF1	0	FBXW7	2	affinity chromatography technology	Castello A (2012)	1
BAG4	2	HSP90AA1	7	affinity chromatography technology	Lau PP (2003)	1
FBXW11	2	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Suzuki H (2000), Suzuki H (2000), Sowa ME (2009), Sowa ME (2009), Coyaud E (2015), Coyaud E (2015), Coyaud E (2015), Huttlin EL (2017), Liu X (2017)	9
PIN1	0	MCL1	1	pull down, affinity chromatography technology	Li QM (2007), Li QM (2007)	2
BCL2L1	0	BMF	0	affinity chromatography technology, unspecified method, two hybrid, unspecified method	Ohgushi M (2005), Kuwana T (2005), Rolland T (2014), Certo M (2006)	4
BBC3	1	BCL2L1	0	affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, affinity chromatography technology	Chen L (2005), Kuwana T (2005), Chipuk JE (2008), Certo M (2006), Tong J (2017)	5
NXF1	0	VDAC1	2	affinity chromatography technology	Castello A (2012)	1
EGLN3	0	HSPA8	4	affinity chromatography technology	Rodriguez J (2016)	1
TP53	0	HUWE1	22	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Chen D (2005), Chen D (2005), Chen D (2005), Chen D (2005), Rolfo A (2012), Rolfo A (2012)	6
PRKAA1	2	PRKAB1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Behrends C (2010), Behrends C (2010), Al-Hakim AK (2005), Lee KM (2011), Havugimana PC (2012), Varjosalo M (2013), Qi J (2008), Launay JM (1996), Launay JM (1996), Launay JM (1996), Launay JM (1996), Dyck JR (1996), Dyck JR (1996), So J (2015), Wan C (2015), Huttlin EL (2017)	16
EGLN3	0	HSPA4	3	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	USP9X	15	affinity chromatography technology	Rodriguez J (2016)	1
BAG4	2	HSPA4	3	affinity chromatography technology	Lau PP (2003)	1
MCL1	1	BIK	0	unspecified method, pull down, unspecified method	Chen L (2005), Warr MR (2011), Certo M (2006)	3
GSK3B	1	BCL2L1	0	enzymatic study	Wang J (2012)	1
BCL2L11	4	MCL1	1	affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen L (2005), Bae J (2000), Hsu SY (1998), Wiggins CM (2010), Warr MR (2011), Sun HL (2009), Stankiewicz AR (2009), Dehan E (2009), Zhong Q (2005), Liao M (2011), Kuwana T (2005), Certo M (2006), Certo M (2006), Konopleva M (2006), Huttlin EL (2015), Knorr KL (2015), Weber A (2016), Rudner J (2011), Rudner J (2011), Huttlin EL (2017)	20
PRKAG1	1	PRKAA1	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cheung PC (2000), Behrends C (2010), Behrends C (2010), Al-Hakim AK (2005), Lee KM (2011), Varjosalo M (2013), Launay JM (1996), Launay JM (1996), Dyck JR (1996), Dyck JR (1996), Rolland T (2014), So J (2015), Huttlin EL (2015), Huttlin EL (2017)	14
MYC	2	HSPA1A	0	affinity chromatography technology	Agrawal P (2010)	1
SKP1	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Staropoli JF (2003), Min KW (2003), Lisztwan J (1998), Zheng N (2002), Ohta T (1999), Bloom J (2006), Kumar R (2005), Megumi Y (2005), Wang W (2004), Read MA (2000), Wu K (2000), Tan P (1999), Mao X (2011), Lin HK (2009), Yano H (2008), Banerjee S (2010), Gao D (2010), Chua YS (2011), Zhang M (2008), Winston JT (1999), Latres E (1999), Latres E (1999), Arai T (2003), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), Emberley ED (2012), Bennett EJ (2010), Gastaldello S (2012), Michel JJ (1998), Michel JJ (1998), Michel JJ (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Furukawa M (2000), Furukawa M (2000), Liu J (2002), Liu J (2002), Liu J (2002), Yu ZK (1998), Yu ZK (1998), Postow L (2013), Cordero-Espinoza L (2013), Zhou W (2014), Zhou W (2014), Hao J (2015), Hao J (2015), Han XR (2016), Liu YQ (2015), Gorelik M (2016), Al-Yacoub N (2016), Reiterer V (2017), Hu Y (2017), Hauri S (2016), Reitsma JM (2017), Reitsma JM (2017), Chen F (2017)	59
BAK1	0	BCL2L1	0	two hybrid, affinity chromatography technology, unspecified method, fluorescent resonance energy transfe, affinity chromatography technology, unspecified method, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Rual JF (2005), Zhang H (2002), Whitfield J (2003), Willis SN (2005), Willis SN (2005), Degterev A (2001), Venkatesan K (2009), Griffiths GJ (1999), Griffiths GJ (1999), Rudner J (2011), Rudner J (2011)	12
PMAIP1	0	BAX	3	affinity chromatography technology	Sun Y (2005)	1
BCL2L1	0	VDAC1	2	pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Weng C (2005), Shi Y (2003), Shimizu S (2000), Shimizu S (2000), Shimizu S (1999), Shimizu S (1999), Ramanathan A (2009)	7
UHRF2	1	PCNA	0	far western blotting, x-ray crystallography, unspecified method, affinity chromatography technology	Mori T (2011), Chen W (2017), Chen W (2017), Lai M (2016)	4
MCL1	1	VDAC1	2	pull down	Weng C (2005)	1
EGLN3	0	PCNA	0	affinity chromatography technology	Rodriguez J (2016)	1
MCL1	1	FLG	17	affinity chromatography technology	Huttlin EL (2015)	1
TP53	0	HSPA4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Muller P (2008), Fraser JA (2010), Sun Y (2007), Wang J (2011), Horikawa I (2014), Horikawa I (2014), Kishor A (2013)	7
CUL1	7	ECM1	1	affinity chromatography technology	Huttlin EL (2017)	1
GSK3B	1	HSP90AA1	7	enzymatic study	Muller P (2012)	1
BAX	3	MCL1	1	two hybrid, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bae J (2000), Stankiewicz AR (2009), Zhang C (2011), Czabotar PE (2011), Czabotar PE (2011), Huttlin EL (2015), Huttlin EL (2017)	7
PINK1	2	HSPA4	3	affinity chromatography technology, affinity chromatography technology	Imai Y (2010), Moriwaki Y (2008)	2
MCL1	1	BMF	0	unspecified method, unspecified method, unspecified method	Chen L (2005), Kuwana T (2005), Certo M (2006)	3
BBC3	1	MCL1	1	affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, unspecified method, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Chen L (2005), Warr MR (2011), Pervin S (2011), Kuwana T (2005), Certo M (2006), Huttlin EL (2015), Tong J (2017), Tong J (2017), Huttlin EL (2017)	9
EGLN3	0	MAPK1	1	two hybrid	Wang J (2011)	1
CUL1	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
TPT1	1	TP53	0	affinity chromatography technology	Amson R (2011)	1
UHRF2	1	BAX	3	far western blotting	Mori T (2011)	1
BCL2L1	0	TP53	0	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Vinayagam A (2011), Tang WH (2014), Saxena R (2016), Stegh AH (2010), Kim EM (2014)	5
BAG3	4	HSPA4	3	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Doong H (2003), Doong H (2003), Gentilella A (2011), Gamerdinger M (2009), Gamerdinger M (2009), Ammirante M (2010), Chen Y (2013), Chen Y (2013)	8
HSPA8	4	BAG3	4	two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Takayama S (1999), Takayama S (1999), Takayama S (1999), Gentilella A (2011), Hishiya A (2011), Chen Y (2013), Chen Y (2013), Taipale M (2014), Taipale M (2014), Rolland T (2014), Hein MY (2015)	11
CUL1	7	HSPA4	3	affinity chromatography technology, affinity chromatography technology	Oshikawa K (2003), Bennett EJ (2010)	2
HSPA4	3	BCL2L11	4	affinity chromatography technology	Ambrosini G (2009)	1
MAPK1	1	TP53	0	affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, imaging technique	Persons DL (2000), How PC (2011), Srivastav RK (2011), Fogeron ML (2013), Chen TC (2014)	5
TP53	0	SKP1	0	affinity chromatography technology	Fogeron ML (2013)	1
PIN1	0	FBXW7	2	affinity chromatography technology, affinity chromatography technology	Min SH (2012), Kourtis N (2015)	2
CUL1	7	BAG4	2	affinity chromatography technology	Bennett EJ (2010)	1
BAG3	4	MCL1	1	affinity chromatography technology, affinity chromatography technology	Boiani M (2013), Boiani M (2013)	2
MYC	2	MAPK1	1	pull down, pull down	Jin Z (2004), Gupta S (1994)	2
CASP3	0	BID	1	enzymatic study, enzymatic study	Paroni G (2001), Walsh JG (2008)	2
DAD1	0	MCL1	1	two hybrid, affinity chromatography technology	Makishima T (2000), Makishima T (2000)	2
TP53	0	HSPA8	4	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Akakura S (2001), Kaur J (1996), Fogeron ML (2013), Horikawa I (2014), Matsumoto H (1994), Matsumoto H (1994), Karras GI (2017)	7
MYC	2	GSK3A	1	affinity chromatography technology, affinity chromatography technology, pull down	Gregory MA (2003), Gregory MA (2003), Gregory MA (2003)	3
PRKAB1	0	PRKAB2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Behrends C (2010), Huttlin EL (2017)	3
CAV1	0	VDAC1	2	affinity chromatography technology	Ramirez CM (2009)	1
MCL1	1	BID	1	unspecified method, affinity chromatography technology, pull down, pull down, affinity chromatography technology, unspecified method	Chen L (2005), Weng C (2005), Weng C (2005), Warr MR (2011), Chipuk JE (2008), Certo M (2006)	6
HSP90AA1	7	FBXW11	2	affinity chromatography technology	Taipale M (2012)	1
MCL1	1	TP53	0	unspecified method, affinity chromatography technology	Lee MS (2014), Zhang X (2016)	2
MCL1	1	TNKS	12	two hybrid, affinity chromatography technology, pull down	Bae J (2003), Bae J (2003), Bae J (2003)	3
AGO2	10	BTRC	1	unspecified method	Elcheva I (2009)	1
PINK1	2	HSPA1A	0	affinity chromatography technology	Murata H (2013)	1
HSPA4	3	HSPA8	4	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical	Hidalgo-de-Quintana J (2008), Havugimana PC (2012), Taipale M (2014), Taipale M (2014), Wan C (2015)	5
AGO2	10	MCL1	1	affinity chromatography technology	Weinmann L (2009)	1
BAG3	4	TPT1	1	affinity chromatography technology, affinity chromatography technology	Chen Y (2013), Chen Y (2013)	2
MCL1	1	CUL1	7	affinity chromatography technology, affinity chromatography technology	Ye M (2017), Feng C (2017)	2
FBXO4	0	SKP1	0	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Cenciarelli C (1999), Cenciarelli C (1999), Cenciarelli C (1999), Li Y (2010), Li Y (2010), Hagens O (2006), Lee EK (2013), Tian X (2015), Huttlin EL (2017), Qie S (2017), Hauri S (2016)	12
NXF1	0	BTRC	1	affinity chromatography technology	Castello A (2012)	1
HSP90AA1	7	FBXW7	2	affinity chromatography technology	Taipale M (2012)	1
PMAIP1	0	MCL1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, unspecified method, affinity chromatography technology, affinity chromatography technology	Chen L (2005), Willis SN (2005), Warr MR (2011), Jin L (2011), Stankiewicz AR (2009), Craxton A (2012), Craxton A (2012), Boiani M (2013), Tang Y (2012), Kuwana T (2005), Certo M (2006), Knorr KL (2015), Park SH (2016)	13
TRAF6	0	VDAC1	2	affinity chromatography technology	Ewing RM (2007)	1
PINK1	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Imai Y (2010), Weihofen A (2008), Weihofen A (2008), Moriwaki Y (2008), Moriwaki Y (2008), Taipale M (2012), Ando M (2017)	7
PCNA	0	MCL1	1	affinity chromatography technology, pull down, two hybrid	Fujise K (2000), Fujise K (2000), Fujise K (2000)	3
HSP90AA1	7	BECN1	2	affinity chromatography technology	Xu C (2011)	1
BAG3	4	SKP1	0	affinity chromatography technology	Chen Y (2013)	1
TP53	0	MAPK10	0	affinity chromatography technology	Hu MC (1997)	1
RANBP6	5	MCL1	1	affinity chromatography technology	Huttlin EL (2017)	1
PRKAB1	0	PRKAG1	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cheung PC (2000), Cheung PC (2000), Behrends C (2010), Behrends C (2010), Wang J (2011), Qi J (2008), Launay JM (1996), Launay JM (1996), Launay JM (1996), Launay JM (1996), Dyck JR (1996), Dyck JR (1996), Huttlin EL (2015), Huttlin EL (2017)	14
HUWE1	22	MYC	2	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Adhikary S (2005), Adhikary S (2005), Adhikary S (2005), Koch HB (2007), Fan L (2015), Zhao X (2008)	6
MCL1	1	STARD9	12	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NXF1	0	UBXN6	1	affinity chromatography technology	Castello A (2012)	1
UHRF2	1	LYN	2	far western blotting	Mori T (2011)	1
MCL1	1	ARG1	0	affinity chromatography technology	Huttlin EL (2017)	1
NXF1	0	HSPA4	3	affinity chromatography technology	Castello A (2012)	1
FBXW11	2	GSK3B	1	two hybrid	Wallach T (2013)	1
EGLN3	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
MCL1	1	HSPA1A	0	affinity chromatography technology	Boiani M (2013)	1
MAPK1	1	VDAC1	2	imaging technique	Galli S (2009)	1
TRIM11	1	PRKAG1	1	affinity chromatography technology	Huttlin EL (2017)	1
PRKN	1	TP53	0	pull down, enzymatic study	Jung YY (2017), Jung YY (2017)	2
NXF1	0	BAG3	4	affinity chromatography technology	Castello A (2012)	1
TP53	0	AGO2	10	affinity chromatography technology	Lunardi A (2010)	1
UNK	3	HSPA4	3	affinity chromatography technology	Murn J (2015)	1
GSK3B	1	TP53	0	affinity chromatography technology, two hybrid	Watcharasit P (2002), Vinayagam A (2011)	2
FBXW11	2	BAG3	4	affinity chromatography technology	Low TY (2014)	1
PRKN	1	FBXO4	0	affinity chromatography technology	Gong Y (2014)	1
BCL2L11	4	BCL2L1	0	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, two hybrid, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen L (2005), Whitfield J (2003), OConnor L (1998), Hsu SY (1998), Ohgushi M (2005), Kuwana T (2005), Wang X (2009), Wang X (2009), Certo M (2006), Huttlin EL (2015), Weber A (2016), Rudner J (2011), Rudner J (2011), Huttlin EL (2017)	14
HSPA8	4	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down	Polanowska-Grabowska R (1997), Giommarelli C (2010), Gano JJ (2010), Skarra DV (2011), Wan C (2015), Sun L (2012)	6
MCL1	1	MCL1	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Bae J (2000), Bae J (2000), Kim JH (2009)	3
TP53	0	PCNA	0	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Banks D (2006), Banks D (2006), Hampp S (2016), Hampp S (2016)	4
CAV1	0	BID	1	affinity chromatography technology, affinity chromatography technology	Zhang M (2011), Zhang M (2011)	2
MCL1	1	HRK	0	unspecified method	Chen L (2005)	1
MCL1	1	UBXN6	1	pull down	Guo X (2017)	1
CUL1	7	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
HUWE1	22	MCL1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Warr MR (2005), Warr MR (2005), Warr MR (2011), Warr MR (2011), Pandya RK (2010), Gomez-Bougie P (2011), Gomez-Bougie P (2011), Schwickart M (2010), Schwickart M (2010), Pervin S (2011), Bewley MA (2011), Bewley MA (2011), Rolfo A (2012), Rolfo A (2012), Stankiewicz AR (2009), Zhong Q (2005), Zhong Q (2005), Liao M (2011), Thompson JW (2014), Park SH (2016), Sander B (2017)	21
ATG12	1	MCL1	1	affinity chromatography technology	Rubinstein AD (2011)	1
HSPA4	3	PRKN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Moore DJ (2008), Hampe C (2006), Tsai YC (2003), Morishima Y (2008), Kalia SK (2004), Kalia SK (2004), Imai Y (2003), Imai Y (2003)	8
MCL1	1	BAG4	2	affinity chromatography technology	Boiani M (2013)	1
FBXW7	2	CUL1	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wu G (2001), Tron AE (2012), Busino L (2012), Busino L (2012), Busino L (2012), Matsumoto A (2011), Bennett EJ (2010), Strohmaier H (2001), Davis MA (2013), JunGang Z (2012), Busino L (2003), Pierce NW (2013), Chung FZ (2014), Yumimoto K (2012), Low TY (2014), Kourtis N (2015), Gorelik M (2016), Gorelik M (2016), Huttlin EL (2017), Reiterer V (2017), Reiterer V (2017), Ye M (2017), Reitsma JM (2017)	23
HSPA1A	0	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kaur J (1996), Fogeron ML (2013), Horikawa I (2014), Matsumoto H (1994), Matsumoto H (1994)	5
MCL1	1	TRIM11	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MYC	2	SKP1	0	affinity chromatography technology, affinity chromatography technology, two hybrid	Koch HB (2007), von der Lehr N (2003), Wang J (2011)	3
MYC	2	BTRC	1	affinity chromatography technology, enzymatic study	Popov N (2010), Popov N (2010)	2
BTRC	1	TP53	0	affinity chromatography technology, affinity chromatography technology	Xia Y (2009), Verma S (2011)	2
FBXO4	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Cenciarelli C (1999), Hagens O (2006), Choo YY (2011), Liu B (2012), Jeong YT (2013), Huttlin EL (2017), Reitsma JM (2017)	8
CUL1	7	AGO2	10	affinity chromatography technology	Bennett EJ (2010)	1
BCL2L1	0	TPT1	1	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, unspecified method	Yang Y (2005), Yang Y (2005), Yang Y (2005), Yang Y (2005), Yang Y (2005)	5
GSK3A	1	MCL1	1	enzymatic study	Ding Q (2007)	1
PRKN	1	HSPA1A	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Imai Y (2002), Imai Y (2002), Imai Y (2002), Zanon A (2013)	4
HUWE1	22	PMAIP1	0	affinity chromatography technology	Gomez-Bougie P (2011)	1
PRKN	1	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kao SY (2009), Kao SY (2009), Zhu X (2017), Zhu X (2017), Zhu X (2017)	5
BTRC	1	MCL1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study	Dehan E (2009), Ding Q (2007), Ding Q (2007), Ding Q (2007), Ding Q (2007)	5
MAPK10	0	MCL1	1	enzymatic study	Li QM (2007)	1
TPT1	1	MCL1	1	affinity chromatography technology	Yang Y (2005)	1
MYC	2	TP53	0	affinity chromatography technology, fluorescent resonance energy transfe	Agrawal P (2010), Ivanov AA (2017)	2
TP53	0	FBXO4	0	affinity chromatography technology	Jin X (2009)	1
UNK	3	HSP90AA1	7	affinity chromatography technology	Murn J (2015)	1
BAG3	4	BCL2L11	4	affinity chromatography technology, affinity chromatography technology	Chen Y (2013), Chen Y (2013)	2
MCL1	1	BOK	1	two hybrid	Hsu SY (1997)	1
FBXW11	2	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Suzuki H (2000), Sowa ME (2009), Watanabe N (2004), Fuchs SY (1999), Tan P (1999), Herter JR (2002), Lievens S (2009), Lievens S (2009), DAnnibale S (2014), Kim TY (2014), Kim TY (2014), Coyaud E (2015), Low TY (2014), Hein MY (2015), Liu X (2017), Hauri S (2016)	16
GSK3B	1	HSPA4	3	enzymatic study, pull down	Muller P (2012), Kawakami F (2011)	2
FBXW11	2	HUWE1	22	affinity chromatography technology, affinity chromatography technology	Low TY (2014), Low TY (2014)	2
PRKN	1	FBXW7	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Staropoli JF (2003), Staropoli JF (2003), Staropoli JF (2003), Gong Y (2014)	4
BAX	3	HSPA4	3	affinity chromatography technology	Guo F (2005)	1
DUSP22	1	MCL1	1	affinity chromatography technology	Li X (2016)	1
MCL1	1	PRKAA1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PRKN	1	HSPA8	4	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Imai Y (2002), Imai Y (2002), Imai Y (2003), Zanon A (2013)	4
HUWE1	22	USP9X	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gomez-Bougie P (2011), Schwickart M (2010), Schwickart M (2010)	3
EGLN3	0	MCL1	1	affinity chromatography technology	Rodriguez J (2016)	1
GSK3B	1	BTRC	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Kitagawa M (1999), Gao C (2014), Gao C (2014), Gao C (2014)	4
MCL1	1	USP9X	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology	Gomez-Bougie P (2011), Gomez-Bougie P (2011), Schwickart M (2010), Schwickart M (2010), Schwickart M (2010), Zhang C (2011), Trivigno D (2012), Peddaboina C (2012)	8
HSP90AA1	7	HSPA1A	0	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Kanelakis KC (2002), Gano JJ (2010), Falsone SF (2005), Brychzy A (2003), Scholz GM (2001), Scholz GM (2001)	6
EDNRA	1	BCL2L11	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BAG3	4	CASP3	0	biochemical	Wan C (2015)	1
HSP90AA1	7	CAV1	0	affinity chromatography technology	Ji Y (2007)	1
BAX	3	VDAC1	2	pull down, pull down	Weng C (2005), Shi Y (2003)	2
MAPK1	1	GSK3B	1	affinity chromatography technology, pull down, enzymatic study	Ding Q (2005), Ding Q (2005), Ding Q (2005)	3
PRKN	1	MAPK1	1	affinity chromatography technology	Um JW (2012)	1
PINK1	2	PRKN	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, genetic interference, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, fluorescent resonance energy transfe, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Shiba K (2009), Shiba K (2009), Geisler S (2010), Um JW (2009), Um JW (2009), Xiong H (2009), Xiong H (2009), Xiong H (2009), Kondapalli C (2012), Kondapalli C (2012), Sha D (2010), Sha D (2010), Sha D (2010), Sha D (2010), Lazarou M (2013), Zheng X (2013), Fedorowicz MA (2014), Vives-Bauza C (2010), Shiba-Fukushima K (2014), Bertolin G (2015), Fiesel FC (2015), Kazlauskaite A (2015), Moore DJ (2006), Moore DJ (2006), Zhang T (2016), Klosowiak JL (2016), Gersch M (2017)	27
SKP1	0	FBXW7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology	Staropoli JF (2003), Wu G (2001), Wu G (2001), Wu G (2001), Hao B (2007), Schuelein C (2011), Busino L (2012), Busino L (2012), Busino L (2012), Matsumoto A (2011), Watanabe N (2004), Strohmaier H (2001), Choi BH (2014), Yumimoto K (2012), Kourtis N (2015), Kourtis N (2015), Hao J (2015), Tian X (2015), Liu YQ (2015), Gorelik M (2016), Gorelik M (2016), Gorelik M (2016), Yeh CH (2016), Reiterer V (2017), Reiterer V (2017), Reiterer V (2017), Kuchay S (2017), Ye M (2017)	28
HSP90AA1	7	FBXO4	0	affinity chromatography technology	Taipale M (2012)	1
BCL2L1	0	BID	1	unspecified method, unspecified method, unspecified method, imaging technique	Chen L (2005), Kuwana T (2005), Certo M (2006), Chen TC (2014)	4
TRIM11	1	PRKAB1	0	affinity chromatography technology	Huttlin EL (2017)	1
BCL2L11	4	BAX	3	affinity chromatography technology	Huttlin EL (2015)	1
CUL1	7	PCNA	0	affinity chromatography technology	Bennett EJ (2010)	1
NXF1	0	BID	1	affinity chromatography technology	Castello A (2012)	1
UNK	3	MCL1	1	affinity chromatography technology	Murn J (2015)	1
MCL1	1	FBXO4	0	affinity chromatography technology	Feng C (2017)	1
BAG3	4	HSP90AA1	7	affinity chromatography technology	Chen Y (2013)	1
EGLN3	0	VDAC1	2	affinity chromatography technology	Rodriguez J (2016)	1
BCL2L1	0	PRKN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Hollville E (2014), Hollville E (2014), Gong Y (2017), Gong Y (2017), Gong Y (2017)	5
BAG3	4	HSPA1A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Doong H (2000), Antoku K (2001), Chen Y (2013), Hein MY (2015)	4
PRKAA1	2	PRKAB2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Behrends C (2010), Behrends C (2010), Al-Hakim AK (2005), Wang J (2011), Varjosalo M (2013), Corominas R (2014), Rolland T (2014), So J (2015), Wan C (2015), Huttlin EL (2017)	10
FBXW7	2	TP53	0	affinity chromatography technology	Huttlin EL (2017)	1
BCL2L11	4	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Busino L (2012), Dehan E (2009), Dehan E (2009), Moustafa-Kamal M (2013), Moustafa-Kamal M (2013), Huttlin EL (2015), Huttlin EL (2017)	7
MCL1	1	PRKAB2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MCL1	1	BAK1	0	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Leu JI (2004), Leu JI (2004), Willis SN (2005), Willis SN (2005), Weng C (2005), Bae J (2000), Warr MR (2011), Stankiewicz AR (2009), Konopleva M (2006), Huttlin EL (2015), Knorr KL (2015), Rudner J (2011), Rudner J (2011), Zhang X (2016), Huttlin EL (2017)	15
MCL1	1	ECM1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NXF1	0	HSP90AA1	7	affinity chromatography technology	Castello A (2012)	1
MAPK1	1	MCL1	1	enzymatic study	Ding Q (2007)	1
EGLN3	0	GSK3B	1	affinity chromatography technology	Rodriguez J (2016)	1
EDNRA	1	MCL1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL1	7	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
MCL1	1	CPT2	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BCL2L1	0	BAX	3	affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Strobel T (1998), Zhang H (2002), Gillissen B (2003), Ren H (2011), Ren H (2011), Chinnaiyan AM (1997), Diaz JL (1997), Wang X (2009), Wang X (2009), Czabotar PE (2011), Czabotar PE (2011), Huttlin EL (2015), Hein MY (2015), Chen TC (2014), Tong J (2017), Huttlin EL (2017), Kim EM (2014)	17
BECN1	2	MCL1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tang Y (2012), Tang Y (2012), Germain M (2011)	3
CASP3	0	BECN1	2	enzymatic study	Luo S (2010)	1