PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
SMAD3	1	MCM3AP	6	two hybrid	Colland F (2004)	1
SMAD9	0	UBQLN4	2	two hybrid	Colland F (2004)	1
SMAD2	5	PAPPA	3	two hybrid	Colland F (2004)	1
SMAD9	0	TERF1	1	two hybrid	Colland F (2004)	1
HMGA2	1	SMAD9	0	affinity chromatography technology	Monzen K (2008)	1
SMAD9	0	MACO1	0	two hybrid	Colland F (2004)	1
SMAD9	0	UBA6	4	two hybrid	Colland F (2004)	1
KDM6A	8	KMT2D	30	affinity chromatography technology, affinity chromatography technology	Lee MG (2007), Kim JH (2014)	2
CEP135	2	CAMSAP1	5	bioid	Gupta GD (2015)	1
SMAD9	0	PNPLA2	2	two hybrid	Colland F (2004)	1
NAGK	4	ARID1B	80	affinity chromatography technology	Huttlin EL (2017)	1
SMAD2	5	CYP11A1	3	two hybrid	Colland F (2004)	1
SMAD9	0	MCM3AP	6	two hybrid	Colland F (2004)	1
SMAD9	0	LRP5	8	two hybrid	Colland F (2004)	1
SMAD9	0	UBQLN1	1	two hybrid	Colland F (2004)	1
SMAD9	0	KAT2B	2	affinity chromatography technology	Kahata K (2004)	1
SMAD9	0	HEY1	2	two hybrid	Colland F (2004)	1
YWHAQ	0	PKP2	4	affinity chromatography technology	Mueller J (2003)	1
SMAD9	0	ARNT	1	two hybrid	Colland F (2004)	1
SMAD2	5	KAT2A	1	affinity chromatography technology	Kahata K (2004)	1
OTUB1	0	SMAD4	9	affinity chromatography technology, pull down	Herhaus L (2013), Herhaus L (2013)	2
SMAD9	0	SMAP2	4	affinity chromatography technology	Boldt K (2016)	1
SMAD9	0	EIF3C	0	two hybrid	Colland F (2004)	1
SMAD9	0	DSTN	0	two hybrid	Colland F (2004)	1
UBQLN4	2	YWHAQ	0	two hybrid	Lim J (2006)	1
SMAD4	9	PSG9	1	two hybrid	Colland F (2004)	1
SMAD9	0	NAGK	4	two hybrid	Colland F (2004)	1
SMAD9	0	CSH1	1	two hybrid	Colland F (2004)	1
SMAD9	0	ASH2L	2	two hybrid	Colland F (2004)	1
EVC2	5	DNAJC7	2	bioid	Gupta GD (2015)	1
SMAD9	0	TINAGL1	0	two hybrid	Colland F (2004)	1
FLI1	2	SMAD3	1	two hybrid	Ravasi T (2010)	1
SMAD9	0	CHPF	1	two hybrid	Colland F (2004)	1
SMAD4	9	SMAD9	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Nishita M (1999), Li X (2015)	3
SMAD4	9	SMAD2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Moren A (2003), Wotton D (1999), Mori N (2001), Wu JW (2002), Wu JW (2002), Nakao A (1997), Wicks SJ (2000), Wu JW (2001), Chen X (1997), Hanai J (1999), Lebrun JJ (1999), Poncelet AC (2001), Razani B (2001), Razani B (2001), Wang B (2008), Moren A (2005), Kurisaki K (2003), Prunier C (2003), Kato Y (2002), Xu J (2000), Wang L (2011), He W (2006), He W (2006), Dupont S (2009), Brown JD (1999), Pardali K (2000), Fu G (2011), Chen W (2007), Gao S (2009), Lin X (2003), Seo SR (2006), Brown KA (2008), Brown KA (2008), Halder SK (2005), Barrios-Rodiles M (2005), Barrios-Rodiles M (2005), Dai F (2007), Chacko BM (2004), Chacko BM (2004), Chacko BM (2004), Wu RY (1997), Wu RY (1997), Tomita M (2004), Colland F (2004), Tang Y (2003), Ding L (2009), Fattet L (2013), Wang J (2011), Ali A (2013), Yamakawa N (2002), Yamakawa N (2002), Li X (2015), Zhou F (2014), Yang Y (2015), Yan X (2016), Zhou F (2017)	56
KDM1A	2	SMAD4	9	affinity chromatography technology	Rivero S (2015)	1
SMAD9	0	MTMR11	2	two hybrid	Colland F (2004)	1
SMAD9	0	TRIP12	20	two hybrid	Colland F (2004)	1
DSTN	0	OTUB1	0	biochemical	Havugimana PC (2012)	1
SMAD3	1	CYP11A1	3	two hybrid	Colland F (2004)	1
SMAD9	0	EXPH5	4	two hybrid	Colland F (2004)	1
SMAD9	0	SF3B1	12	two hybrid	Colland F (2004)	1
OTUB1	0	SMAD3	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Herhaus L (2013), Herhaus L (2013), Herhaus L (2013)	3
SMAD3	1	CSH2	1	two hybrid	Colland F (2004)	1
SMAD9	0	EIF3F	1	two hybrid	Colland F (2004)	1
GRN	2	PKP2	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SMAP2	4	ZNF143	0	affinity chromatography technology	Boldt K (2016)	1
SMAD2	5	PSG9	1	two hybrid	Colland F (2004)	1
TOB1	1	SMAD4	9	affinity chromatography technology	Yoshida Y (2000)	1
SMAD9	0	ABTB1	1	two hybrid	Colland F (2004)	1
OTUB1	0	DNAJC7	2	affinity chromatography technology	Scholz CC (2016)	1
SMAD7	1	HEYL	1	two hybrid	Colland F (2004)	1
SMAD9	0	SVEP1	10	two hybrid	Colland F (2004)	1
SMAD9	0	AFF1	1	two hybrid	Colland F (2004)	1
SMAD9	0	CEP135	2	two hybrid	Colland F (2004)	1
SMAD9	0	TTC37	3	two hybrid	Colland F (2004)	1
SMAD9	0	UNC45A	1	two hybrid	Colland F (2004)	1
SMAD2	5	SMAD7	1	genetic interference, pull down, affinity chromatography technology	Lebrun JJ (1999), Zhang S (2007), Yan X (2016)	3
SMAD3	1	SVEP1	10	two hybrid	Colland F (2004)	1
SMAD7	1	SMAD3	1	genetic interference, genetic interference, affinity chromatography technology, protein complementation assay	Datta PK (2000), Lebrun JJ (1999), Yan X (2016), Yan X (2016)	4
SMAD9	0	DSG4	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NOTCH1	25	KDM1A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yatim A (2012), Yatim A (2012), Yatim A (2012)	3
ACTB	8	DSTN	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
RBMS1	1	ZNF143	0	affinity chromatography technology	Boldt K (2016)	1
SMAD2	5	RNF123	11	two hybrid	Colland F (2004)	1
SMAD9	0	CXXC5	1	two hybrid	Colland F (2004)	1
EIF3F	1	EIF3C	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Havugimana PC (2012), Huttlin EL (2015), Martineau Y (2014), Wan C (2015), Huttlin EL (2017)	6
SMAD9	0	ZSCAN4	1	two hybrid	Colland F (2004)	1
SMAD9	0	PPARD	4	two hybrid	Colland F (2004)	1
SMAD9	0	RNF123	11	two hybrid	Colland F (2004)	1
SMAD9	0	TBCD	4	two hybrid	Colland F (2004)	1
SMAD9	0	RRBP1	7	two hybrid	Colland F (2004)	1
SMAD3	1	HEYL	1	two hybrid	Colland F (2004)	1
SMAD3	1	LEMD3	4	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Brown KA (2008), Gao S (2009), Huttlin EL (2015), Huttlin EL (2017)	4
LRP5	8	DKK1	1	imaging technique, affinity chromatography technology, affinity chromatography technology	Xu Q (2004), Huttlin EL (2015), Huttlin EL (2017)	3
SMAD9	0	RBMS1	1	affinity chromatography technology	Boldt K (2016)	1
SMAD9	0	DNAJA3	2	two hybrid	Colland F (2004)	1
SMAD9	0	AP2A1	1	two hybrid	Colland F (2004)	1
SMAD9	0	BAZ1A	5	two hybrid	Colland F (2004)	1
SMAD7	1	KAT2B	2	affinity chromatography technology	Monteleone G (2005)	1
SMAD9	0	SECISBP2	4	two hybrid	Colland F (2004)	1
SMAD9	0	MAN1C1	0	two hybrid	Colland F (2004)	1
SMAD7	1	CXXC5	1	two hybrid	Colland F (2004)	1
SMAD4	9	SMAD7	1	genetic interference, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Lebrun JJ (1999), Moren A (2005), Moren A (2005), Moren A (2005), Zhang S (2007), Yan X (2016)	6
SMAD9	0	SPTBN1	6	two hybrid	Colland F (2004)	1
OTUB1	0	KDM1A	2	two hybrid	Weimann M (2013)	1
SMAD9	0	SMAD7	1	affinity chromatography technology	Yan X (2016)	1
YWHAQ	0	PABPC4	2	pull down, biochemical	Meek SE (2004), Wan C (2015)	2
SMAD3	1	CXXC5	1	two hybrid	Colland F (2004)	1
NOTCH1	25	RFX1	3	affinity chromatography technology	Yatim A (2012)	1
PPARD	4	RANBP9	5	two hybrid	Albers M (2005)	1
CSH1	1	CSH2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SMAD4	9	CSH2	1	two hybrid	Colland F (2004)	1
SMAD2	5	DNAJC7	2	two hybrid	Colland F (2004)	1
SMAD9	0	CTR9	10	two hybrid	Colland F (2004)	1
SMAD9	0	E4F1	3	two hybrid	Colland F (2004)	1
SMAD9	0	PPP2R5E	4	two hybrid	Colland F (2004)	1
SMAD2	5	PSAP	3	two hybrid	Colland F (2004)	1
SMAD9	0	SNRNP70	2	two hybrid	Colland F (2004)	1
SMAD9	0	RANBP9	5	two hybrid	Colland F (2004)	1
SMAD9	0	RMND5A	0	two hybrid	Colland F (2004)	1
SMAD2	5	ZEB2	7	two hybrid	Colland F (2004)	1
HEY1	2	NOTCH1	25	genetic interference	Tang Y (2008)	1
SMAD3	1	ZNF83	1	two hybrid	Colland F (2004)	1
HMGA2	1	E4F1	3	pull down, affinity chromatography technology, far western blotting	Tessari MA (2003), Tessari MA (2003), Tessari MA (2003)	3
SMAD9	0	ZNF83	1	two hybrid	Colland F (2004)	1
SMAD9	0	PLEC	39	two hybrid	Colland F (2004)	1
SMAD9	0	CAMSAP1	5	two hybrid	Colland F (2004)	1
SMAD2	5	ARID1B	80	affinity chromatography technology	He W (2006)	1
SPTBN1	6	SMAD2	5	affinity chromatography technology	Tang Y (2003)	1
SMAD4	9	RFX1	3	two hybrid	Colland F (2004)	1
SMAD3	1	SNRNP70	2	two hybrid	Colland F (2004)	1
LMO4	1	TINAGL1	0	two hybrid	Colland F (2004)	1
SMAD9	0	DKK1	1	two hybrid	Colland F (2004)	1
SMAD3	1	KAT2B	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Prokova V (2005), Itoh S (2000), Itoh S (2000), Kahata K (2004), Dai M (2012)	5
SMAD3	1	HEY1	2	two hybrid	Colland F (2004)	1
SMAD2	5	CSH1	1	two hybrid	Colland F (2004)	1
SMAD9	0	DST	13	two hybrid	Colland F (2004)	1
SMAD9	0	ARID1B	80	two hybrid	Colland F (2004)	1
SMAD9	0	SMAD9	0	affinity chromatography technology	Nishita M (1999)	1
SMAD3	1	UBQLN4	2	two hybrid	Wang J (2011)	1
EIF3F	1	NOTCH1	25	affinity chromatography technology, imaging technique	Moretti J (2010), Moretti J (2010)	2
SMAD2	5	BAZ1A	5	two hybrid	Colland F (2004)	1
SMAD3	1	PAPPA	3	two hybrid	Colland F (2004)	1
SMAD9	0	SIL1	1	two hybrid	Colland F (2004)	1
SMAD2	5	ABTB1	1	two hybrid	Colland F (2004)	1
EVC2	5	UNC45A	1	bioid	Gupta GD (2015)	1
SMAD9	0	FLI1	2	two hybrid	Colland F (2004)	1
SMAD9	0	PSAP	3	two hybrid	Colland F (2004)	1
MTMR11	2	DNAJA3	2	affinity chromatography technology	St-Denis N (2016)	1
SMAD2	5	CSH2	1	two hybrid	Colland F (2004)	1
KDM6A	8	ASH2L	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee MG (2007), Mak AB (2010), De Santa F (2007)	3
EIF3E	1	EIF3C	0	affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Luke-Glaser S (2007), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Luke-Glaser S (2007), Huttlin EL (2017)	6
YWHAQ	0	ACTB	8	affinity chromatography technology	Pozuelo-Rubio M (2010)	1
SPTBN1	6	SMAD4	9	affinity chromatography technology, affinity chromatography technology	Tang Y (2003), Tang Y (2003)	2
EIF3F	1	EIF3E	1	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Luke-Glaser S (2007), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	6
RMND5A	0	KDM1A	2	affinity chromatography technology	Lampert F (2018)	1
SMAD9	0	PHKA2	6	two hybrid	Colland F (2004)	1
RRBP1	7	DSTN	0	affinity chromatography technology	Ewing RM (2007)	1
SMAD9	0	SMAD2	5	two hybrid	Colland F (2004)	1
RMND5A	0	PKP2	4	affinity chromatography technology	Lampert F (2018)	1
QARS	1	PLEC	39	biochemical	Wan C (2015)	1
PSMD8	1	SIL1	1	biochemical	Wan C (2015)	1
SMAD3	1	ACTB	8	affinity chromatography technology	Grimsby S (2004)	1
PPARD	4	KDM1A	2	affinity chromatography technology, two hybrid	Weimann M (2013), Weimann M (2013)	2
SMAD9	0	PIR	0	two hybrid	Colland F (2004)	1
SMAP2	4	RBMS1	1	affinity chromatography technology	Boldt K (2016)	1
SMAD3	1	NOTCH1	25	pull down, affinity chromatography technology	Blokzijl A (2003), Blokzijl A (2003)	2
SMAD9	0	ZNF592	6	two hybrid	Colland F (2004)	1
SMAD9	0	ZEB2	7	two hybrid	Colland F (2004)	1
EVC2	5	MACO1	0	bioid	Gupta GD (2015)	1
SNRNP70	2	UBQLN1	1	biochemical	Havugimana PC (2012)	1
SMAD9	0	YWHAQ	0	two hybrid	Colland F (2004)	1
SMAD2	5	LEMD3	4	affinity chromatography technology, two hybrid	Brown KA (2008), Hellemans J (2004)	2
SMAD9	0	VPS8	2	two hybrid	Colland F (2004)	1
SMAD9	0	ARHGAP9	2	two hybrid	Colland F (2004)	1
SMAD9	0	PSMD8	1	two hybrid	Colland F (2004)	1
TERF1	1	PABPC4	2	affinity chromatography technology	Giannone RJ (2010)	1
SMAD9	0	ACTB	8	two hybrid	Colland F (2004)	1
SMAD9	0	PABPC4	2	two hybrid	Colland F (2004)	1
RANBP9	5	RMND5A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kobayashi N (2007), Kobayashi N (2007), Huttlin EL (2015), Huttlin EL (2017), Boldt K (2016), Lampert F (2018)	6
SMAD9	0	ERVV-1	1	two hybrid	Colland F (2004)	1
SMAD9	0	CSH2	1	two hybrid	Colland F (2004)	1
SMAD9	0	ZNF557	3	two hybrid	Colland F (2004)	1
SMAD3	1	SMAD2	5	affinity chromatography technology, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Nakao A (1997), Lebrun JJ (1999), Dumont E (2003), Brown KA (2008), Brown KA (2008), Wu RY (1997), Wu RY (1997), Tang Y (2003), Tang Y (2003), Wang J (2011), Huttlin EL (2015), Huttlin EL (2017)	12
SMAD9	0	PELP1	3	two hybrid	Colland F (2004)	1
SMAD2	5	NAGK	4	two hybrid	Colland F (2004)	1
RBMS1	1	UBQLN1	1	biochemical	Havugimana PC (2012)	1
FLI1	2	KAT2B	2	affinity chromatography technology, affinity chromatography technology	Asano Y (2007), Asano Y (2009)	2
E4F1	3	SF3B1	12	affinity chromatography technology	Huttlin EL (2017)	1
SMAD9	0	KDM6A	8	two hybrid	Colland F (2004)	1
HEY1	2	PLEC	39	affinity chromatography technology	Lopez-Mateo I (2016)	1
SMAD9	0	CLPB	3	two hybrid	Colland F (2004)	1
SMAD9	0	VCPIP1	4	two hybrid	Colland F (2004)	1
SMAD4	9	CSH1	1	two hybrid	Colland F (2004)	1
ACTB	8	OTUB1	0	affinity chromatography technology	Juris SJ (2006)	1
TERF1	1	KDM1A	2	two hybrid	Weimann M (2013)	1
ARNT	1	HEY1	2	two hybrid	Chin MT (2000)	1
SMAD9	0	TWNK	2	two hybrid	Colland F (2004)	1
PIR	0	DSTN	0	biochemical	Wan C (2015)	1
SMAD9	0	KMT2D	30	two hybrid	Colland F (2004)	1
TOB1	1	SMAD9	0	affinity chromatography technology	Yoshida Y (2000)	1
SMAD3	1	RANBP9	5	two hybrid	Colland F (2004)	1
SMAD9	0	VSIG8	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SMAD9	0	DNAJC7	2	two hybrid	Colland F (2004)	1
SMAD3	1	KAT2A	1	affinity chromatography technology	Kahata K (2004)	1
SMAD9	0	MTMR10	0	two hybrid	Colland F (2004)	1
NOTCH1	25	SMAD9	0	affinity chromatography technology	Yatim A (2012)	1
SMAD9	0	FTL	0	two hybrid	Colland F (2004)	1
SMAD3	1	SMAD4	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Seoane J (2004), Moren A (2003), Wu JW (2002), Nakao A (1997), Hanai J (1999), Lebrun JJ (1999), Poncelet AC (2001), Jablonska E (2010), Prunier C (2003), Kato Y (2002), Kaimori A (2010), Tang LY (2011), Tang LY (2011), Dupont S (2009), Dupont S (2009), Pardali K (2000), Kardassis D (2000), Xu L (2003), Fu G (2011), Chen W (2007), Kang JM (2012), Gao S (2009), Li H (2009), Li H (2009), Brown KA (2008), Brown KA (2008), Halder SK (2005), Barrios-Rodiles M (2005), Dai F (2007), Dai F (2007), Chacko BM (2004), Chacko BM (2004), Chacko BM (2004), Stroschein SL (1999), Stroschein SL (1999), Stroschein SL (1999), Wu RY (1997), Wu RY (1997), Wu RY (1997), Wu RY (1997), Tomita M (2004), Colland F (2004), Colland F (2004), Tang Y (2003), Ding L (2009), Fattet L (2013), Wang J (2011), Xue J (2014), Ali A (2013), Gao S (2009), Yamakawa N (2002), Yamakawa N (2002), Wang G (2005), Li X (2015), Zhou F (2014), Yang Y (2015), Yan X (2016), Yan X (2016), Wu Y (2017), Wu Y (2017)	60
SMAD9	0	GRN	2	two hybrid	Colland F (2004)	1
KAT2B	2	SMAD2	5	pull down, affinity chromatography technology, affinity chromatography technology	Itoh S (2000), Kahata K (2004), Dai M (2012)	3
SMAD9	0	ASB2	1	two hybrid	Colland F (2004)	1
NAGK	4	TERF1	1	affinity chromatography technology	Huttlin EL (2017)	1
SPTBN1	6	SMAD3	1	affinity chromatography technology, affinity chromatography technology	Tang Y (2003), Tang Y (2003)	2
SMAD9	0	PKP2	4	two hybrid	Colland F (2004)	1
SMAD9	0	RFX1	3	two hybrid	Colland F (2004)	1
SMAD9	0	LMO4	1	two hybrid	Colland F (2004)	1
DNAJA3	2	KDM1A	2	affinity chromatography technology, two hybrid	Weimann M (2013), Weimann M (2013)	2
SMAD9	0	PRMT6	2	affinity chromatography technology, two hybrid	Weimann M (2013), Weimann M (2013)	2
SMAD9	0	QARS	1	two hybrid	Colland F (2004)	1
SMAD9	0	ZNF587B	0	two hybrid	Colland F (2004)	1
KMT2D	30	ASH2L	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down	Patel SR (2007), Mo R (2006), Mo R (2006), Mo R (2006), Kim JH (2014), Li Y (2016), Alicea-Velazquez NL (2016)	7
HEY1	2	ACTB	8	affinity chromatography technology	Lopez-Mateo I (2016)	1
RBMS1	1	RRBP1	7	biochemical	Havugimana PC (2012)	1
KAT2B	2	ACTB	8	affinity chromatography technology, affinity chromatography technology	Obrdlik A (2008), Obrdlik A (2008)	2
SMAD4	9	LMO4	1	two hybrid	Rolland T (2014)	1
TOB1	1	SMAD3	1	affinity chromatography technology	Xiong B (2006)	1
SMAD3	1	SMAD9	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SMAD9	0	MAN1A2	1	two hybrid	Colland F (2004)	1
SMAD2	5	PSMD8	1	two hybrid	Colland F (2004)	1
SMAD9	0	ZNF143	0	affinity chromatography technology	Boldt K (2016)	1
SMAD9	0	PAPPA	3	two hybrid	Colland F (2004)	1
TERF1	1	TBCD	4	two hybrid	Lee OH (2011)	1
SMAD2	5	SNRNP70	2	two hybrid	Colland F (2004)	1
SMAD9	0	CYP11A1	3	two hybrid	Colland F (2004)	1
SMAD9	0	KDM1A	2	affinity chromatography technology, two hybrid	Weimann M (2013), Weimann M (2013)	2
SMAD9	0	OTUB1	0	two hybrid	Colland F (2004)	1
SMAD9	0	LEMD3	4	two hybrid, affinity chromatography technology, affinity chromatography technology	Colland F (2004), Huttlin EL (2015), Huttlin EL (2017)	3
SMAD2	5	RANBP9	5	two hybrid	Colland F (2004)	1
SMAD9	0	TRIM29	2	two hybrid	Colland F (2004)	1
PRMT6	2	HMGA2	1	enzymatic study, far western blotting	Sgarra R (2006), Sgarra R (2006)	2
TERF1	1	DST	13	affinity chromatography technology	Giannone RJ (2010)	1
KDM1A	2	PELP1	3	affinity chromatography technology, pull down, imaging technique, imaging technique	Nair SS (2010), Nair SS (2010), Nair SS (2010), Nair SS (2010)	4
SMAD9	0	METAP1	0	two hybrid	Colland F (2004)	1
OTUB1	0	SMAD2	5	affinity chromatography technology, affinity chromatography technology, pull down	Herhaus L (2013), Herhaus L (2013), Herhaus L (2013)	3
DNAJA3	2	PRMT6	2	affinity chromatography technology, two hybrid	Weimann M (2013), Weimann M (2013)	2
SMAD9	0	PSG9	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UBQLN1	1	SIL1	1	two hybrid	Rolland T (2014)	1
ZNF557	3	PRMT6	2	two hybrid	Weimann M (2013)	1
UBQLN4	2	UBQLN1	1	two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology	Lim J (2006), Havugimana PC (2012), Lee DY (2013), Lee DY (2013)	4
SMAD9	0	DIAPH3	7	two hybrid	Colland F (2004)	1
SMAD3	1	ZEB2	7	affinity chromatography technology, affinity chromatography technology, two hybrid	Long J (2005), Long J (2005), Colland F (2004)	3
SMAD9	0	HEYL	1	two hybrid	Colland F (2004)	1
SMAD9	0	EVC2	5	two hybrid	Colland F (2004)	1
SMAD9	0	EIF3E	1	two hybrid	Colland F (2004)	1
SMAD4	9	SNRNP70	2	two hybrid	Colland F (2004)	1
SMAD9	0	MGAT1	1	two hybrid	Colland F (2004)	1
SMAD9	0	KAT2A	1	affinity chromatography technology	Kahata K (2004)	1
NOTCH1	25	RANBP9	5	affinity chromatography technology	Yatim A (2012)	1