PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
SIT1	1	ZAP70	5	affinity chromatography technology	Marie-Cardine A (1999)	1
KIT	4	PIK3R1	6	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique	De Sepulveda P (1999), van Dijk TB (2000), Serve H (1994), Zhu MJ (2007), Zhu MJ (2007), Yokouchi M (1997), Chen TC (2014)	7
CD4	1	UNC119	4	affinity chromatography technology, pull down	Gorska MM (2004), Gorska MM (2004)	2
RASA1	3	DOK2	2	affinity chromatography technology, affinity chromatography technology	Dunant NM (2000), Di Cristofano A (1998)	2
LCK	0	TRAT1	0	pull down	Brdicka T (2000)	1
NOTCH1	25	CBL	7	affinity chromatography technology, affinity chromatography technology	Jehn BM (2002), Platonova N (2015)	2
LCK	0	PAG1	5	pull down	Brdicka T (2000)	1
PXN	1	MAPK1	1	imaging technique	Chen TC (2014)	1
FASLG	0	PIK3R1	6	imaging technique	Chen TC (2014)	1
CD5	1	PTPN6	0	affinity chromatography technology	Perez-Villar JJ (1999)	1
HSP90AA1	7	IKBKG	0	affinity chromatography technology, affinity chromatography technology	Gano JJ (2010), Hein MY (2015)	2
CD4	1	ZAP70	5	affinity chromatography technology	Thome M (1995)	1
CD5	1	RASA1	3	affinity chromatography technology	Dennehy KM (1998)	1
LCK	0	SYK	3	affinity chromatography technology, pull down, two hybrid	Thome M (1995), Thome M (1995), Moon KD (2005)	3
PIK3R1	6	PIK3CA	8	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Woscholski R (1994), Chamberlain MD (2004), Ren SY (2005), Kamal M (2010), Sun M (2010), Hein MY (2015), Fang D (2001), Xiong Y (2009), Ivanov AA (2017)	9
SH3KBP1	1	RAF1	3	affinity chromatography technology	Sato S (2013)	1
PTK2B	6	BCAR1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Manie SN (1997), Anfosso F (2001), Astier A (1997), Takahashi T (2003)	4
NEDD9	3	BCAR1	6	affinity chromatography technology	Law SF (1999)	1
G3BP1	4	YWHAQ	0	affinity chromatography technology	Jain S (2016)	1
CD3E	0	LCK	0	affinity chromatography technology, affinity chromatography technology	Munoz P (2003), Munoz P (2003)	2
PTPN22	3	CD247	1	affinity chromatography technology	Wu J (2006)	1
SMAD2	5	CISH	1	two hybrid	Colland F (2004)	1
HSP90AA1	7	PTK2B	6	affinity chromatography technology	Taipale M (2012)	1
STAT3	0	LCK	0	two hybrid	Grossmann A (2015)	1
PXN	1	PTK2B	6	affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hiregowdara D (1997), Hiregowdara D (1997), Matsuya M (1998), Matsuya M (1998), Anfosso F (2001), Ivankovic-Dikic I (2000)	6
G3BP1	4	HSP90AA1	7	affinity chromatography technology	Jain S (2016)	1
CSNK2B	5	BRCA1	7	pull down, two hybrid, pull down	OBrien KA (1999), OBrien KA (1999), OBrien KA (1999)	3
PIK3CA	8	SMAD3	1	pull down	Richard KC (2006)	1
PXN	1	NEDD9	3	affinity chromatography technology	Zhang Z (1999)	1
LCK	0	LCK	0	enzymatic study	Cooper JC (2010)	1
LCK	0	FAS	2	pull down	Schlottmann KE (1996)	1
PTPRC	1	LCK	0	affinity chromatography technology, pull down, affinity chromatography technology	Koretzky GA (1993), Ng DH (1996), Jury EC (2004)	3
SOCS2	1	PTK2B	6	two hybrid, affinity chromatography technology, affinity chromatography technology	Lee SH (2010), Lee SH (2010), Lee SH (2010)	3
ARHGAP17	1	LCK	0	pull down	Richnau N (2001)	1
CD44	1	LCK	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Taher TE (1996), Taher TE (1996), Ilangumaran S (1998), Ilangumaran S (1998)	4
SMURF1	4	UBC	7	affinity chromatography technology, enzymatic study, pull down	Xie Y (2013), Kristariyanto YA (2015), Zhang Y (2017)	3
PXN	1	PIK3R1	6	imaging technique	Chen TC (2014)	1
CD4	1	SYK	3	affinity chromatography technology	Thome M (1995)	1
SQSTM1	0	CTNND1	4	affinity chromatography technology	Behrends C (2010)	1
PTPN6	0	LAT	0	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Matalon O (2016), Matalon O (2016), Matalon O (2016)	3
LCK	0	PIK3R1	6	pull down	Kapeller R (1994)	1
SQSTM1	0	FAS	2	affinity chromatography technology, affinity chromatography technology	Liang X (2013), Liang X (2013)	2
ZAP70	5	CD5	1	affinity chromatography technology	Gary-Gouy H (1997)	1
SH3KBP1	1	ARHGAP17	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havrylov S (2009), Wells CD (2006), Huttlin EL (2017)	3
HSP90AA1	7	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Johnson N (2013), Johnson N (2013), Ertych N (2016)	3
LCK	0	NR3C1	2	affinity chromatography technology, affinity chromatography technology	Loewenberg M (2006), Loewenberg M (2006)	2
UBC	7	LCK	0	unspecified method, x-ray crystallography	Kang J (2008), Kang J (2008)	2
PIK3R1	6	BRCA1	7	pull down	Ren SY (2005)	1
SOS1	5	LAT	0	imaging technique	Houtman JC (2006)	1
LCK	0	PI4KA	7	pull down	Prasad KV (1993)	1
PIK3R1	6	WAS	0	affinity chromatography technology, pull down	Banin S (1996), Banin S (1996)	2
HAVCR2	0	PIK3CA	8	affinity chromatography technology	Huttlin EL (2017)	1
AJUBA	2	LCK	0	two hybrid	Feng Y (2005)	1
HAVCR2	0	PIK3R1	6	affinity chromatography technology	Huttlin EL (2017)	1
SH3KBP1	1	BCAR1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000), Tibaldi EV (2003)	3
IL2RB	1	STAT3	0	pull down	Delespine-Carmagnat M (2000)	1
LCK	0	WASL	2	enzymatic study	Torres E (2006)	1
DOK2	2	LCK	0	two hybrid	Grossmann A (2015)	1
LCK	0	BRCA1	7	two hybrid	Hill SJ (2014)	1
HSP90AA1	7	STAT3	0	affinity chromatography technology	Sato N (2003)	1
MAPK1	1	RAF1	3	affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Lin YL (2000), Dougherty MK (2005), Zhu J (2005), Blaukat A (2000), Wang J (2009), Wang J (2009), Wang J (2009)	7
LCK	0	SOS1	5	unspecified method	Tran T (2005)	1
PTK2B	6	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Haglund K (2004), Haglund K (2004), Sanjay A (2001), Schmidt MH (2003)	4
BAG6	2	PI4KA	7	affinity chromatography technology	Hein MY (2015)	1
STAT3	0	CBL	7	two hybrid	Grossmann A (2015)	1
PTPN6	0	PIK3R1	6	two hybrid	Sathish JG (2001)	1
IKBKG	0	LCK	0	pull down	Fenner BJ (2010)	1
SQSTM1	0	UBC	7	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, affinity chromatography technology, unspecified method, pull down, pull down, pull down, affinity chromatography technology, imaging technique, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, imaging technique, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique	Vinayagam A (2011), Vadlamudi RK (1996), Tanji K (2012), Matsumoto G (2011), Long J (2008), Long J (2008), Najat D (2009), Najat D (2009), Hocking LJ (2004), Boh BK (2011), Long J (2010), Seibenhener ML (2004), Seibenhener ML (2004), Seibenhener ML (2004), Fenner BJ (2009), Nathan JA (2013), Ciani B (2003), Shi J (2013), Goode A (2014), Bish RA (2007), Lu K (2014), Zhou L (2014), Zhou L (2014), Vadlamudi RK (1996), Long J (2008), Cavey JR (2006), Cavey JR (2006), Kirkin V (2009), Nakayasu ES (2013), Nakayasu ES (2013), Lim J (2015), Milan E (2015), Milan E (2015), Ordureau A (2015), Wurzer B (2015), Zhang X (2017), Wang L (2017), Liu X (2017), Peng H (2017), Donohue E (2014), Nibe Y (2017), Nibe Y (2017), Govindaraju VK (2017)	43
LCK	0	WAS	0	affinity chromatography technology, enzymatic study	Nervi S (2005), Torres E (2006)	2
CD3E	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	de Aos I (1997), Alcazar I (2009)	2
CBLB	3	LCK	0	affinity chromatography technology	Kumar S (2011)	1
KHDRBS1	1	SH3KBP1	1	unspecified method, affinity chromatography technology	Asbach B (2012), Havrylov S (2009)	2
FAS	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Kleber S (2008), Kleber S (2008)	2
CD2	2	PTPRC	1	pull down	Schraven B (1990)	1
CSNK2B	5	LCK	0	two hybrid	Vinayagam A (2011)	1
PRKCQ	3	LCK	0	two hybrid	Ron D (1999)	1
SH3KBP1	1	WASL	2	affinity chromatography technology	Havrylov S (2009)	1
LAT	0	PIK3R1	6	affinity chromatography technology, pull down	Paz PE (2001), Paz PE (2001)	2
RAF1	3	CD44	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTK2B	6	RASA1	3	affinity chromatography technology, pull down, affinity chromatography technology	Chow A (2000), Chow A (2000), Zrihan-Licht S (2000)	3
PTPN22	3	LCK	0	affinity chromatography technology, affinity chromatography technology	Wu J (2006), Wu J (2006)	2
SMAD3	1	NR3C1	2	affinity chromatography technology, pull down, affinity chromatography technology, pull down	Li G (2003), Li G (2003), Song CZ (1999), Song CZ (1999)	4
BRCA1	7	UBE3A	4	pull down	Wu-Baer F (2003)	1
FAM174A	2	PI4KA	7	affinity chromatography technology	Huttlin EL (2017)	1
CD44	1	STAT3	0	affinity chromatography technology	Su YJ (2011)	1
SOS1	5	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000)	2
UBE3A	4	DLG1	2	pull down	Matsumoto Y (2006)	1
CD4	1	NR3C1	2	affinity chromatography technology, affinity chromatography technology	Loewenberg M (2006), Loewenberg M (2006)	2
STAT3	0	PIK3R1	6	two hybrid	Grossmann A (2015)	1
SIT1	1	SYK	3	affinity chromatography technology	Marie-Cardine A (1999)	1
RASA1	3	PXN	1	affinity chromatography technology	Shikata Y (1999)	1
STAT3	0	MAPK1	1	affinity chromatography technology	Lo RK (2006)	1
LCK	0	PIK3CA	8	affinity chromatography technology, pull down	Sade H (2004), Prasad KV (1993)	2
LCK	0	LAT	0	biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology	Munoz P (2003), Munoz P (2003), Jiang Y (2007), Jiang Y (2007)	4
SKAP1	0	PTPRC	1	two hybrid, affinity chromatography technology	Wu L (2002), Wu L (2002)	2
LCK	0	SKAP1	0	pull down, affinity chromatography technology	Marie-Cardine A (1997), Marie-Cardine A (1999)	2
CD44	1	PTPRC	1	biochemical	Ilangumaran S (1998)	1
SYK	3	PIK3R1	6	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Moon KD (2005), Moon KD (2005), Moon KD (2005), Moon KD (2005), Huang ZY (2006)	5
LCK	0	SOCS2	1	affinity chromatography technology	Venkitachalam S (2011)	1
LCK	0	SQSTM1	0	pull down	Joung I (1996)	1
CD38	0	CD247	1	affinity chromatography technology, biochemical	Munoz P (2003), Munoz P (2003)	2
CD2	2	LCK	0	affinity chromatography technology, pull down	Bell GM (1996), Bell GM (1996)	2
THY1	0	LCK	0	affinity chromatography technology	Thomas PM (1992)	1
LCK	0	CTNND1	4	enzymatic study	Martinez MC (2003)	1
CBLB	3	PTK2B	6	affinity chromatography technology	Fan Y (2014)	1
UBC	7	CISH	1	affinity chromatography technology, affinity chromatography technology	Jensik PJ (2015), Jensik PJ (2015)	2
CD44	1	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
SH3KBP1	1	CBLB	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down	Szymkiewicz I (2002), Szymkiewicz I (2002), Szymkiewicz I (2002), Havrylov S (2009), Moncalian G (2006), Jozic D (2005), Jozic D (2005), Kowanetz K (2003), Ceregido MA (2013), Ceregido MA (2013), Ceregido MA (2013)	11
SQSTM1	0	PIK3R1	6	far western blotting, affinity chromatography technology	Sung CK (1998), Sung CK (1998)	2
PAK2	0	LCK	0	pull down	Kaerkkaeinen S (2006)	1
CBLB	3	ZAP70	5	affinity chromatography technology, affinity chromatography technology	Zhang Z (1999), Kumar S (2011)	2
LCK	0	NOTCH1	25	affinity chromatography technology, affinity chromatography technology	Sade H (2004), Sade H (2004)	2
YWHAQ	0	CBL	7	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Pedraza-Alva G (2001), Liu YC (1996), Liu YC (1996), Melander F (2004), Subramanian RR (2001), Liu YC (1997), Liu YC (1997), Brehme M (2009)	8
CBL	7	ZAP70	5	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, x-ray crystallography	Lupher ML (1996), Meng W (1999), Wang HY (2001), Rao N (2000), Lupher ML (1997), Okabe S (2006), Zhang Z (1999), Lupher ML (1996), Dou H (2012), Dou H (2012), Gabrielsen M (2017)	11
CBL	7	PXN	1	affinity chromatography technology, affinity chromatography technology	Rafiq K (2011), Salgia R (1996)	2
SOCS2	1	SOCS1	1	affinity chromatography technology	Wu KL (2007)	1
UBC	7	G3BP1	4	affinity chromatography technology	Matsumoto M (2005)	1
LCK	0	CD55	0	imaging technique	Chen TC (2014)	1
YWHAQ	0	RAF1	3	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Ewing RM (2007), Yeung K (2000), Van Der Hoeven PC (2000), Liu YC (1996), Subramanian RR (2001), ONeill E (2004), Rajalingam K (2005), Zhu J (2005), Bonnefoy-Berard N (1995), So J (2015)	10
TRPV4	2	LCK	0	affinity chromatography technology	Xu H (2003)	1
LCK	0	SOCS1	1	affinity chromatography technology, affinity chromatography technology	Venkitachalam S (2011), Venkitachalam S (2011)	2
PTPN22	3	CBL	7	affinity chromatography technology	Cohen S (1999)	1
PIK3CA	8	SQSTM1	0	two hybrid	Wang J (2008)	1
CBL	7	PTPN6	0	affinity chromatography technology	Kant AM (2002)	1
ADAM10	2	DLG1	2	affinity chromatography technology	Marcello E (2007)	1
SMAD3	1	BRCA1	7	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dubrovska A (2005), Dubrovska A (2005), Dubrovska A (2005), Li H (2009), Li H (2009)	5
CBL	7	AXL	4	affinity chromatography technology	Valverde P (2005)	1
CSNK2B	5	BAG6	2	two hybrid	Vinayagam A (2011)	1
LAT	0	CBL	7	affinity chromatography technology	Jiang Y (2007)	1
LCK	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Loewenberg M (2006), Taipale M (2012)	2
BAG6	2	LCK	0	affinity chromatography technology, affinity chromatography technology	Rangachari M (2012), Rangachari M (2012)	2
LCK	0	PTK2B	6	affinity chromatography technology	Ganju RK (1997)	1
WAS	0	CBLB	3	affinity chromatography technology	Watanabe Y (2013)	1
HSP90AA1	7	PRKCQ	3	affinity chromatography technology	Taipale M (2012)	1
RAF1	3	LCK	0	affinity chromatography technology	Pathan NI (1996)	1
SMAD2	5	SMURF1	4	affinity chromatography technology, affinity chromatography technology, two hybrid	Komuro A (2004), Ito I (2010), Colland F (2004)	3
SYK	3	PTK2B	6	affinity chromatography technology	Ganju RK (2000)	1
SOCS1	1	PIK3R1	6	two hybrid	Grossmann A (2015)	1
LCK	0	LZTS2	4	two hybrid	Rolland T (2014)	1
AXL	4	LCK	0	far western blotting	Braunger J (1997)	1
YWHAQ	0	PRKCQ	3	affinity chromatography technology, affinity chromatography technology, far western blotting	Meller N (1996), Meller N (1996), Meller N (1996)	3
STAT3	0	KHDRBS1	1	affinity chromatography technology, affinity chromatography technology	Sanchez-Margalet V (2001), Sanchez-Margalet V (2001)	2
LCK	0	MAPK1	1	enzymatic study	Tapinos N (2005)	1
NR3C1	2	STAT3	0	pull down, affinity chromatography technology, affinity chromatography technology	Lerner L (2003), Zhang Z (1997), Wang W (2015)	3
KHDRBS1	1	LCK	0	affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology	Fusaki N (1997), Loewenberg M (2006), Tran T (2005), Nervi S (2005)	4
CD4	1	LCK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Hawash IY (2002), Foti M (2002), Bernhard OK (2004), Loewenberg M (2006), Py B (2007)	5
PIK3R1	6	SH3KBP1	1	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid	Gout I (2000), Tossidou I (2010), Borthwick EB (2004), Borthwick EB (2004)	4
PTK2B	6	NEDD9	3	affinity chromatography technology	Manie SN (1997)	1
LCK	0	G3BP1	4	enzymatic study	Rahmouni S (2005)	1
CD2	2	CD5	1	affinity chromatography technology	Carmo AM (1999)	1
PTPN6	0	PTK2B	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ganju RK (2000), Ganju RK (2000), Kumar S (1999), Kumar S (1999), Kumar S (1999)	5
SOCS3	0	SOCS2	1	affinity chromatography technology	Tannahill GM (2005)	1
PTPN6	0	CTNND1	4	affinity chromatography technology, pull down, affinity chromatography technology	Keilhack H (2000), Keilhack H (2000), Keilhack H (2000)	3
RASA1	3	G3BP1	4	affinity chromatography technology	Gallouzi IE (1998)	1
LCK	0	SMAD2	5	pull down	Richard KC (2006)	1
BCAR1	6	LCK	0	pull down	Manie SN (1997)	1
CBL	7	CBLB	3	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Rorsman C (2016)	2
DLG1	2	LCK	0	affinity chromatography technology, pull down, imaging technique	Hanada T (1997), Hanada T (1997), Chen TC (2014)	3
NOTCH1	25	MAPK1	1	affinity chromatography technology, affinity chromatography technology	Yatim A (2012), Yatim A (2012)	2
HSP90AA1	7	AXL	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Krishnamoorthy GP (2013), Krishnamoorthy GP (2013)	3
CD48	1	LCK	0	affinity chromatography technology	Hawash IY (2002)	1
UBE3A	4	UBC	7	enzymatic study, enzymatic study, pull down	Schwarz SE (1998), Ronchi VP (2013), Zhang X (2017)	3
PTPN6	0	PAG1	5	pull down	Brdicka T (2000)	1
NOTCH1	25	ADAM10	2	imaging technique	Chastagner P (2017)	1
ZAP70	5	PTPN6	0	pull down	Plas DR (1996)	1
LCK	0	UNC119	4	affinity chromatography technology, pull down	Gorska MM (2004), Gorska MM (2004)	2
KHDRBS1	1	RASA1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Sanchez-Margalet V (2001), Sanchez-Margalet V (2001), Jabado N (1998), Jabado N (1998), Koch CA (1992), Marengere LE (1992), Gold MR (1993), Darby C (1994)	8
NEDD9	3	SMAD3	1	two hybrid, pull down, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	Feng L (2004), Nourry C (2004), Feng L (2004), Feng L (2004), Liu X (2000), Liu X (2000)	6
CBLB	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavagna-Sevenier C (1998), Elly C (1999), Elly C (1999), Alcazar I (2009), Fang D (2001)	5
BRCA1	7	MAPK1	1	affinity chromatography technology, affinity chromatography technology	Yan Y (2008), Yan Y (2008)	2
5175	0	PTPN6	0	pull down, far western blotting, affinity chromatography technology, pull down	Pumphrey NJ (1999), Pumphrey NJ (1999), Hua CT (1998), Hua CT (1998)	4
PTK2B	6	SH3KBP1	1	affinity chromatography technology	Schmidt MH (2003)	1
SYK	3	PXN	1	affinity chromatography technology	Fernandez R (1998)	1
LCK	0	ZAP70	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pelosi M (1999), Thome M (1995), Lupher ML (1996)	3
SMAD3	1	SMURF1	4	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Komuro A (2004), Colland F (2004), Li Y (2017), Li Y (2017)	4
UNC119	4	LZTS2	4	affinity chromatography technology	Huttlin EL (2017)	1
SQSTM1	0	NOTCH1	25	affinity chromatography technology, affinity chromatography technology	Ahn JS (2016), Ahn JS (2016)	2
ADAM10	2	LCK	0	affinity chromatography technology	Poghosyan Z (2002)	1
CBL	7	SYK	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Lupher ML (1998), Lupher ML (1998), Bertagnolo V (2001), Melander F (2003), Macglashan D (2004), Rao N (2001), Rao N (2001), Yankee TM (1999), Saci A (2000), Moon KD (2005), Lottin-Divoux S (2006), Grossmann AH (2004), Ota S (2000), Ota S (2000), Panchamoorthy G (1996), Marcilla A (1995), Justa-Schuch D (2016)	17
CD5	1	LCK	0	affinity chromatography technology	Bamberger M (2011)	1
UHRF2	1	BCAR1	6	far western blotting	Mori T (2011)	1
CD247	1	LCK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Munoz P (2003), Munoz P (2003), Yang M (2015)	3
SMAD3	1	NOTCH1	25	pull down, affinity chromatography technology	Blokzijl A (2003), Blokzijl A (2003)	2
NOTCH1	25	PIK3CA	8	affinity chromatography technology	Sade H (2004)	1
LCK	0	SH3KBP1	1	affinity chromatography technology	Narita T (2005)	1
LCK	0	CBL	7	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Rao N (2002), Tsygankov AY (1996), Reedquist KA (1996), Nervi S (2005)	4
LCK	0	CDKAL1	2	two hybrid	Rolland T (2014)	1
PTPRC	1	CD4	1	fluorescent resonance energy transfe	Mittler RS (1991)	1
FASLG	0	LCK	0	pull down	Wenzel J (2001)	1
UBC	7	SH3KBP1	1	pull down, x-ray crystallography, pull down, x-ray crystallography, pull down, x-ray crystallography	Bezsonova I (2008), Korzhnev DM (2009), Ortega Roldan JL (2013), Ortega Roldan JL (2013), Stamenova SD (2007), Bezsonova I (2008)	6
SMAD2	5	NEDD9	3	affinity chromatography technology	Liu X (2000)	1
PTPN6	0	SYK	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ganju RK (2000), Dustin LB (1999), Dustin LB (1999)	3
SMAD3	1	PTPN6	0	affinity chromatography technology	Brown KA (2008)	1
AXL	4	PIK3R1	6	enzymatic study, affinity chromatography technology	Braunger J (1997), Weinger JG (2008)	2
SH3KBP1	1	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000), Petrelli A (2002), Soubeyran P (2002), Soubeyran P (2002), Szymkiewicz I (2002), Borinstein SC (2000), Schmidt MH (2006), Schmidt MH (2004), Schmidt MH (2004), Verdier F (2002), Verdier F (2002), Feshchenko EA (2004), Chandra V (2010), Niiro H (2012), Feng L (2011), Havrylov S (2009), Zhang J (2009), Zhang J (2009), Ababou A (2009), Le Bras S (2007), Jozic D (2005), Kowanetz K (2004), Kowanetz K (2003), Kowanetz K (2003), Tibaldi EV (2003), Tibaldi EV (2003), Take H (2000), Take H (2000), Schroeder B (2012), Schroeder B (2012), Peruzzi G (2007), Selbach M (2006), Sato S (2013), Taipale M (2014), Taipale M (2014), Diesenberg K (2015), Petrelli A (2002), Huttlin EL (2017)	39
SH2B3	2	LCK	0	affinity chromatography technology	Li Y (2000)	1
UHRF2	1	PTPRC	1	far western blotting	Mori T (2011)	1
ADAM15	2	LCK	0	affinity chromatography technology, pull down, pull down	Poghosyan Z (2002), Poghosyan Z (2002), Kaerkkaeinen S (2006)	3
SOCS3	0	YWHAQ	0	two hybrid	Grossmann A (2015)	1
ZAP70	5	LAT	0	enzymatic study, enzymatic study, imaging technique, affinity chromatography technology	Paz PE (2001), Perez-Villar JJ (2002), Houtman JC (2006), Xie JJ (2013)	4
KIT	4	SOCS1	1	two hybrid, affinity chromatography technology	De Sepulveda P (1999), De Sepulveda P (1999)	2
NR3C1	2	RAF1	3	affinity chromatography technology	Widen C (2000)	1
PIK3CA	8	SMAD2	5	pull down	Richard KC (2006)	1
LCK	0	SMAD3	1	pull down	Richard KC (2006)	1
CBL	7	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Gesbert F (1998), Gesbert F (1998), Zhang S (1999), Dufour C (2008), Feshchenko EA (2004), Kassenbrock CK (2002), Fang D (2001), Valiya Veettil M (2011), Miao H (2002), Miao H (2002), Ueno H (1998), Gelkop S (2001), Wang Y (1999), Saci A (2000), Matsuo T (1996), Matsuo T (1996), Jackson JG (2000), Meisner H (1995), Saci A (1999), Saci A (1999), Beckwith M (1996), Beckwith M (1996), Song JJ (2010), Hartley D (1996), Finkelstein LD (2000), Ren SY (2005), Hunter S (1997), Hunter S (1997), Jain SK (1997), Jain SK (1997), Swaminathan G (2007), van Leeuwen JE (1999), Ren SY (2005), Ren SY (2005), Alcazar I (2009), Liu YC (1997), Matsuo T (1996), Matsuo T (1996), Lottin-Divoux S (2006), Kitanaka A (1996), Liu YC (1997), Grossmann AH (2004), Panchamoorthy G (1996), Panchamoorthy G (1996), Chernock RD (2001), Chernock RD (2001), Fukazawa T (1995), Fukazawa T (1995), Brehme M (2009), Hakak Y (2000), Hakak Y (2000), Fukazawa T (1995), Liu Y (1999), Cerboni C (1998), Cerboni C (1998), Momose H (2003), Fukazawa T (1996), Fukazawa T (1996), Bulut GB (2013), Bulut GB (2013), Grossmann A (2015)	61
ZAP70	5	RASA1	3	affinity chromatography technology	Neumeister EN (1995)	1
SMURF1	4	LCK	0	enzymatic study	Andrews PS (2010)	1
BAG6	2	HAVCR2	0	affinity chromatography technology	Rangachari M (2012)	1
SMAD3	1	SMAD2	5	affinity chromatography technology, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Nakao A (1997), Lebrun JJ (1999), Dumont E (2003), Brown KA (2008), Brown KA (2008), Wu RY (1997), Wu RY (1997), Tang Y (2003), Tang Y (2003), Wang J (2011), Huttlin EL (2015), Huttlin EL (2017)	12
KHDRBS1	1	DLG1	2	unspecified method	Asbach B (2012)	1
CD38	0	ZAP70	5	biochemical	Munoz P (2003)	1
PTPN22	3	ZAP70	5	affinity chromatography technology, affinity chromatography technology	Wu J (2006), Wu J (2006)	2
UNC119	4	CD247	1	affinity chromatography technology, pull down	Gorska MM (2004), Gorska MM (2004)	2
5175	0	MAPK1	1	affinity chromatography technology	Ilan N (2000)	1
PIK3CA	8	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sattler M (1997), Sattler M (1997), Chernock RD (2001), Chernock RD (2001), Brehme M (2009)	5
CD247	1	TRAT1	0	affinity chromatography technology	Kirchgessner H (2001)	1
SOS1	5	PTPN6	0	affinity chromatography technology	Kon-Kozlowski M (1996)	1
PTPN6	0	LCK	0	enzymatic study, enzymatic study, pull down	Yu CL (2000), Chiang GG (2001), Lorenz U (1994)	3
KIT	4	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zeng S (2005), Brizzi MF (1996), Dong Y (2015)	3
SOCS3	0	RASA1	3	pull down, affinity chromatography technology	Cacalano NA (2001), Cacalano NA (2001)	2
CD247	1	ZAP70	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mustelin T (1995), Wang HY (2001), La Face DM (1997), Huang H (2010), Huang H (2010), Hubert P (1996), Yang M (2015)	7
CBL	7	SOS1	5	affinity chromatography technology	Wang Y (1999)	1
AJUBA	2	SQSTM1	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Feng Y (2005), Feng Y (2005), Feng Y (2005)	3
UBC	7	KHDRBS1	1	pull down	Zhang X (2017)	1
NEDD9	3	LCK	0	affinity chromatography technology	Minegishi M (1996)	1
PIK3R1	6	SOS1	5	imaging technique	Chen TC (2014)	1
SYK	3	CD3E	0	pull down	Bu JY (1995)	1
ZAP70	5	CD3E	0	pull down, affinity chromatography technology	Bu JY (1995), Hubert P (1996)	2
PIK3R1	6	CD247	1	affinity chromatography technology	Fang D (2001)	1
SMAD3	1	SQSTM1	0	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
BCAR1	6	PXN	1	affinity chromatography technology, affinity chromatography technology	Salgia R (1996), Chellaiah MA (2001)	2
LCK	0	SOCS3	0	affinity chromatography technology	Venkitachalam S (2011)	1
CD5	1	CBL	7	affinity chromatography technology, biochemical	Dennehy KM (1998), Roa NS (2013)	2
UBC	7	BRCA1	7	pull down, enzymatic study	Sobhian B (2007), Zhao GY (2007)	2
RASA1	3	SOCS1	1	affinity chromatography technology, affinity chromatography technology	Madonna S (2008), Madonna S (2008)	2
SQSTM1	0	MAPK1	1	affinity chromatography technology	Linares JF (2011)	1
PIK3R1	6	KHDRBS1	1	affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Sanchez-Margalet V (2001), Shen Z (1999), Shen Z (1999), Asbach B (2012), Asbach B (2012), Asbach B (2012), Sung CK (1994), Sung CK (1994)	8
PTPN22	3	CD3E	0	affinity chromatography technology, affinity chromatography technology	Wu J (2006), Wu J (2006)	2
BAG6	2	FAS	2	two hybrid	Wang J (2011)	1
CBL	7	UBC	7	x-ray crystallography, pull down, affinity chromatography technology, pull down, enzymatic study, pull down, enzymatic study, x-ray crystallography, pull down, pull down, enzymatic study	Peschard P (2007), Peschard P (2007), Davies GC (2004), Davies GC (2004), Kassenbrock CK (2004), Zhou ZR (2008), Kim M (2004), Dou H (2013), Liu N (2015), Buetow L (2016), Kliza K (2017)	11
PTPRC	1	CD247	1	pull down	Furukawa T (1994)	1
KIT	4	PTPN6	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Kozlowski M (1998), Kozlowski M (1998), Kozlowski M (1998), Yi T (1993), Yi T (1993)	5
CD3E	0	CD247	1	affinity chromatography technology, affinity chromatography technology, imaging technique	Munoz P (2003), Munoz P (2003), Chen TC (2014)	3
SOCS3	0	PTK2B	6	two hybrid, affinity chromatography technology	Masuhara M (1997), Zhang S (2008)	2
STAT3	0	SYK	3	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
CD2	2	CD48	1	pull down	Zhu B (2002)	1
SQSTM1	0	CD48	1	affinity chromatography technology	Milan E (2015)	1
CD4	1	HSP90AA1	7	affinity chromatography technology	Bernhard OK (2004)	1
CBL	7	SMAD3	1	affinity chromatography technology, affinity chromatography technology	Kang JM (2012), Kang JM (2012)	2
YWHAQ	0	SMURF1	4	affinity chromatography technology	Ichimura T (2013)	1
PRKCQ	3	CBL	7	enzymatic study, affinity chromatography technology	Liu Y (1999), Liu Y (1999)	2
IL2RB	1	SOCS1	1	affinity chromatography technology	Sporri B (2001)	1
SH3KBP1	1	KIT	4	affinity chromatography technology	Szymkiewicz I (2002)	1
CD38	0	LCK	0	affinity chromatography technology	Munoz P (2003)	1
WASL	2	HSP90AA1	7	pull down	Park SJ (2005)	1
SYK	3	PAG1	5	pull down	Brdicka T (2000)	1
STAT3	0	DOK2	2	two hybrid	Grossmann A (2015)	1
CD38	0	CD3E	0	affinity chromatography technology, biochemical	Munoz P (2003), Munoz P (2003)	2
SMAD2	5	KHDRBS1	1	two hybrid	Colland F (2004)	1
PXN	1	LCK	0	affinity chromatography technology	Ostergaard HL (1998)	1
RAF1	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stancato LF (1993), Dogan T (2008), Mollapour M (2010), Du J (2006), Maloney A (2007), Fiskus W (2007), Giommarelli C (2010), Arlander SJ (2006), ONeill E (2004), Taipale M (2012), Zhu J (2005), Schneider C (1996), Mollapour M (2014), Atabakhsh E (2012), Mitra S (2016)	15
BCAR1	6	PIK3R1	6	affinity chromatography technology, pull down	Li E (2000), Li E (2000)	2
CBL	7	CD247	1	affinity chromatography technology, affinity chromatography technology	Wang HY (2001), Wang HY (2001)	2
UBC	7	IKBKG	0	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, x-ray crystallography, pull down, unspecified method, x-ray crystallography, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Dynek JN (2010), Dynek JN (2010), Chiaravalli J (2011), Laplantine E (2009), Hubeau M (2011), Lo YC (2009), Ikeda F (2010), Cordier F (2009), Cordier F (2009), Cordier F (2009), Renner F (2011), Fenner BJ (2009), Fenner BJ (2009), Ivins FJ (2009), Rahighi S (2009), Rahighi S (2009), Zhu G (2007), Zhu G (2007), Niu J (2011), Keusekotten K (2013), van Wijk SJ (2013), Hooper C (2014), Wagner S (2008), Saul VV (2014), Gleason CE (2011), Komander D (2009), Kensche T (2012), Skaug B (2011), Ea CK (2006), Ea CK (2006), Lo YC (2009), Laplantine E (2009), Laplantine E (2009), Emmerich CH (2013), Dubosclard V (2015), Vincendeau M (2015), Vincendeau M (2016), Zhang X (2017), Fang R (2017), Kliza K (2017), Joo D (2016), Fang R (2017), Hauenstein AV (2017)	43
SH3KBP1	1	PAK2	0	affinity chromatography technology, far western blotting	Kurakin AV (2003), Kurakin AV (2003)	2
PTPN22	3	LZTS2	4	bioid	St-Denis N (2016)	1
G3BP1	4	CTNND1	4	affinity chromatography technology	Jain S (2016)	1
IL2RB	1	CISH	1	affinity chromatography technology, affinity chromatography technology	Aman MJ (1999), Aman MJ (1999)	2
IKBKG	0	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Martin P (2006), Zotti T (2014)	2
LCK	0	KIT	4	affinity chromatography technology	Krystal GW (1998)	1
BCAR1	6	CBL	7	affinity chromatography technology	Sawasdikosol S (1996)	1
BRCA1	7	YWHAQ	0	affinity chromatography technology	Ertych N (2016)	1
UBE3A	4	LCK	0	two hybrid, pull down	Oda H (1999), Oda H (1999)	2
LAT	0	CD247	1	affinity chromatography technology	Munoz P (2003)	1
PIK3CA	8	NEDD9	3	two hybrid	Wang J (2008)	1
FAS	2	FASLG	0	biochemical, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Gajate C (2005), Micheau O (2003), Starling GC (1997), Schneider P (1997), Legler DF (2003), Tao RH (2011), Chen TC (2014)	7
UBC	7	CBLB	3	pull down, pull down, pull down, pull down, enzymatic study	De Schutter J (2009), Fenner BJ (2009), Zhou ZR (2008), Raasi S (2005), Kim M (2004)	5
CD2	2	SH3KBP1	1	pull down, two hybrid, affinity chromatography technology, x-ray crystallography, pull down, pull down	Hutchings NJ (2003), Tibaldi EV (2003), Tibaldi EV (2003), Ceregido MA (2013), Ceregido MA (2013), Ceregido MA (2013)	6
CBLB	3	KIT	4	affinity chromatography technology	Szymkiewicz I (2002)	1
5175	0	PIK3R1	6	affinity chromatography technology	Pellegatta F (1998)	1
MAPK1	1	SMAD3	1	enzymatic study, affinity chromatography technology	Alarcon C (2009), Brown KA (2008)	2
UHRF2	1	LCK	0	far western blotting	Mori T (2011)	1
ADAM15	2	MAPK1	1	affinity chromatography technology	Zhong JL (2008)	1
CBL	7	CD38	0	fluorescent resonance energy transfe, affinity chromatography technology, fluorescent resonance energy transfe	Shen M (2009), Shen M (2008), Shen M (2008)	3
SYK	3	LAT	0	enzymatic study	Paz PE (2001)	1
PRKCQ	3	IKBKG	0	affinity chromatography technology	Lee KY (2005)	1
SIT1	1	LCK	0	affinity chromatography technology	Marie-Cardine A (1999)	1
YWHAQ	0	LCK	0	affinity chromatography technology	Heo SR (2009)	1
CTLA4	0	LCK	0	affinity chromatography technology	Miyatake S (1998)	1
WAS	0	CBL	7	affinity chromatography technology	Watanabe Y (2013)	1
RIN3	2	LCK	0	two hybrid	Grossmann A (2015)	1
BRCA1	7	KHDRBS1	1	affinity chromatography technology	Ertych N (2016)	1
NR3C1	2	HSP90AA1	7	imaging technique, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down	Jibard N (1999), Hulkko SM (2000), Kanelakis KC (2002), Hecht K (1997), de Castro M (1996), van den Berg JD (1996), Stancato LF (1996), Kovacs JJ (2005), Silverstein AM (1997), Gradin K (1994), Gano JJ (2010), Miyamoto-Sato E (2010), Mollapour M (2014), Moraes LA (2005), Wochnik GM (2004), Woodford MR (2016), Lievens S (2016), McGuire J (1994)	18
PXN	1	ADAM10	2	affinity chromatography technology	Lee JH (2013)	1
UBC	7	CD2	2	pull down	Nathan JA (2013)	1
HAVCR2	0	LCK	0	affinity chromatography technology	Rangachari M (2012)	1
ZAP70	5	PAG1	5	pull down	Brdicka T (2000)	1
LCK	0	IL2RB	1	affinity chromatography technology	Reneer MC (2011)	1
ARHGAP17	1	PIK3R1	6	pull down	Richnau N (2001)	1
LAT	0	CD3E	0	affinity chromatography technology	Munoz P (2003)	1
FASLG	0	PIK3CA	8	unspecified method	Voss M (2009)	1
LCK	0	5175	0	enzymatic study	Cao MY (1998)	1
KIT	4	PIK3CA	8	affinity chromatography technology	Furitsu T (1993)	1
LCK	0	FAM174A	2	unspecified method	Tran T (2005)	1
LCK	0	CISH	1	affinity chromatography technology	Venkitachalam S (2011)	1
LCK	0	RASA1	3	enzymatic study	Giglione C (2001)	1
CBLB	3	SYK	3	affinity chromatography technology, enzymatic study	Elly C (1999), Wirnsberger G (2016)	2
PIK3R1	6	ZAP70	5	affinity chromatography technology	Moon KD (2005)	1
SOCS3	0	IL2RB	1	pull down	Cohney SJ (1999)	1
MS4A1	1	LCK	0	affinity chromatography technology	Deans JP (1995)	1