PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
KPNB1	3	TRIM3	2	affinity chromatography technology, affinity chromatography technology	Mukherjee S (2016), Mukherjee S (2016)	2
7179	0	KPNB1	3	affinity chromatography technology, bioid	Yadav L (2017), Yadav L (2017)	2
KPNB1	3	NUP153	1	pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nakielny S (1999), Nakielny S (1999), Kehlenbach RH (2000), Ben-Efraim I (2001), Walther TC (2003), Ciciarello M (2010), Hein MY (2015), Hein MY (2015)	8
KPNA4	0	IPO9	8	biochemical	Wan C (2015)	1
NUP50	0	KPNA2	0	pull down, two hybrid, affinity chromatography technology	Lindsay ME (2002), Rolland T (2014), Huttlin EL (2017)	3
TERF1	1	IPO5	0	two hybrid	Lee OH (2011)	1
NUP85	6	RANBP2	9	bioid	Kim DI (2014)	1
7179	0	IPO8	9	affinity chromatography technology, bioid	Yadav L (2017), Yadav L (2017)	2
TERF1	1	KPNB1	3	pull down, affinity chromatography technology	Forwood JK (2002), Giannone RJ (2010)	2
IPO9	8	IPO7	3	biochemical	Wan C (2015)	1
7179	0	AMFR	2	affinity chromatography technology	Yadav L (2017)	1
KPNB1	3	RAE1	0	pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology	Blower MD (2005), Blower MD (2005), Blower MD (2005), Wan C (2015), Hein MY (2015)	5
KPNB1	3	IPO7	3	pull down, affinity chromatography technology	Goerlich D (1997), Hein MY (2015)	2
KPNB1	3	AMFR	2	affinity chromatography technology, affinity chromatography technology, pull down	Zhong Y (2011), Zhong Y (2011), Zhong Y (2011)	3
PPM1D	11	KPNB1	3	affinity chromatography technology, affinity chromatography technology	St-Denis N (2016), Yadav L (2017)	2
KPNA1	5	NUP50	0	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rolland T (2014), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
NUP85	6	NUP153	1	bioid, affinity chromatography technology	Kim DI (2014), Hein MY (2015)	2
NUP85	6	NUP62	1	bioid	Kim DI (2014)	1
KPNB1	3	RCC1	2	pull down, affinity chromatography technology, affinity chromatography technology	Hood FE (2007), Hein MY (2015), Huttlin EL (2017)	3
TERF1	1	KPNA2	0	affinity chromatography technology	Giannone RJ (2010)	1
NUP85	6	NUP50	0	bioid	Kim DI (2014)	1
NUP107	1	NUP62	1	affinity chromatography technology	Hein MY (2015)	1
KPNA2	0	KPNA3	0	biochemical	Wan C (2015)	1
RAN	1	NXF1	0	pull down, pull down	Shamsher MK (2002), Katahira J (1999)	2
IPO5	0	RAN	1	pull down, affinity chromatography technology, biochemical	Yaseen NR (1997), Lipowsky G (2000), Wan C (2015)	3
KPNB1	3	SMAD3	1	pull down, affinity chromatography technology	Xiao Z (2000), Xiao Z (2000)	2
KPNA3	0	IPO8	9	biochemical	Wan C (2015)	1
KPNA4	0	NUP50	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	3
NOTCH1	25	KPNB1	3	affinity chromatography technology, affinity chromatography technology	Yatim A (2012), Mukherjee S (2016)	2
EGFR	5	KPNB1	3	affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Tong J (2014)	2
TP53	0	SMN1	0	affinity chromatography technology, pull down, two hybrid	Young PJ (2002), Young PJ (2002), Vinayagam A (2011)	3
NUP107	1	NUP85	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Loiodice I (2004), Kaur S (2010), Glavy JS (2007), Wan C (2015), Kim DI (2014), Kim DI (2014), Kim DI (2014), Hein MY (2015)	8
7179	0	IPO7	3	affinity chromatography technology	Yadav L (2017)	1
NUP153	1	RAE1	0	affinity chromatography technology	Hein MY (2015)	1
KPNA3	0	NUP50	0	two hybrid	Rolland T (2014)	1
EGFR	5	RANBP1	0	affinity chromatography technology	Foerster S (2013)	1
RAN	1	KPNA4	0	affinity chromatography technology	Huttlin EL (2017)	1
CFTR	5	KPNB1	3	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
PPP1CB	9	KPNB1	3	affinity chromatography technology, bioid	Yadav L (2017), Yadav L (2017)	2
NUP153	1	KPNA2	0	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
CFTR	5	IPO7	3	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
KPNA2	0	RANBP2	9	two hybrid	Wang J (2011)	1
RAN	1	NUP62	1	affinity chromatography technology	Huttlin EL (2017)	1
TAF10	0	KPNA2	0	pull down, affinity chromatography technology	Soutoglou E (2005), Soutoglou E (2005)	2
NUP62	1	NUP153	1	pull down, affinity chromatography technology	Stochaj U (2006), Stochaj U (2006)	2
RAE1	0	NUP62	1	affinity chromatography technology	Sowa ME (2009)	1
NUP107	1	RAE1	0	affinity chromatography technology	Hein MY (2015)	1
NUP153	1	KPNA1	5	affinity chromatography technology	Hein MY (2015)	1
UBE2I	0	TAF10	0	enzymatic study	Jakobs A (2007)	1
RCC1	2	DLGAP5	2	affinity chromatography technology	Huttlin EL (2017)	1
RANBP2	9	IPO5	0	biochemical	Wan C (2015)	1
IPO5	0	IPO7	3	biochemical	Wan C (2015)	1
NXF1	0	KPNA2	0	affinity chromatography technology	Castello A (2012)	1
NXF1	0	ERBB2	6	affinity chromatography technology	Castello A (2012)	1
KPNA3	0	RCC1	2	pull down, affinity chromatography technology, affinity chromatography technology	Talcott B (2000), Huttlin EL (2015), Huttlin EL (2017)	3
NXF1	0	RCC1	2	affinity chromatography technology	Castello A (2012)	1
NUP98	5	RAE1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Pritchard CE (1999), Pritchard CE (1999), Wong RW (2008), Sowa ME (2009), Ren Y (2010), Blower MD (2005), Wong RW (2006), Funasaka T (2011), Funasaka T (2011), Funasaka T (2011), Quan B (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Salsi V (2016)	15
EGFR	5	NUP85	6	affinity chromatography technology	Foerster S (2013)	1
TP53	0	SMAD3	1	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Cordenonsi M (2003), Cordenonsi M (2003), Lu D (2013), Ali A (2013)	4
CFTR	5	IPO5	0	affinity chromatography technology	Wang X (2006)	1
KPNA1	5	DCAF8	1	affinity chromatography technology, affinity chromatography technology	Wu F (2012), Wu F (2012)	2
KPNA3	0	KPNA6	1	biochemical	Kristensen AR (2012)	1
NUP153	1	RCC1	2	affinity chromatography technology	Hein MY (2015)	1
KPNA1	5	KPNB1	3	pull down, pull down, pull down, biochemical, affinity chromatography technology, pull down	Koehler M (1999), Percipalle P (1997), Plafker SM (2000), Havugimana PC (2012), Hein MY (2015), Tsujii A (2015)	6
SMAD3	1	NUP153	1	pull down	Xu L (2003)	1
NXF1	0	RAE1	0	affinity chromatography technology, affinity chromatography technology	Bachi A (2000), Bachi A (2000)	2
TAF10	0	KPNB1	3	pull down, affinity chromatography technology	Soutoglou E (2005), Soutoglou E (2005)	2
RANBP2	9	KPNB1	3	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Yaseen NR (1999), Delphin C (1997), Ben-Efraim I (2001), Walther TC (2003), Chi NC (1996), Chi NC (1996), Hein MY (2015)	7
RCC1	2	TP53	0	two hybrid	Vinayagam A (2011)	1
PPP1CC	2	NUP153	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
IPO5	0	IPO9	8	biochemical	Wan C (2015)	1
HIST1H1C	2	KPNB1	3	affinity chromatography technology, affinity chromatography technology, pull down	Kim K (2008), Kim K (2008), Kim K (2008)	3
ING1	2	KPNB1	3	affinity chromatography technology, affinity chromatography technology	Russell MW (2008), Russell MW (2008)	2
ING1	2	KPNA2	0	affinity chromatography technology, affinity chromatography technology	Russell MW (2008), Russell MW (2008)	2
NUP62	1	KPNA1	5	pull down	Hu T (1996)	1
RCC1	2	NUSAP1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGFR	5	IPO9	8	affinity chromatography technology	Foerster S (2013)	1
NUP85	6	NUP98	5	biochemical, bioid	Wan C (2015), Kim DI (2014)	2
KPNA2	0	KPNA1	5	biochemical	Wan C (2015)	1
RCC1	2	KPNA4	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Hood FE (2007), Hood FE (2007), Huttlin EL (2015), Huttlin EL (2017)	4
PPM1D	11	KPNA2	0	affinity chromatography technology, affinity chromatography technology	St-Denis N (2016), Yadav L (2017)	2
CFTR	5	RANBP1	0	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
NOTCH1	25	IPO5	0	affinity chromatography technology	Yatim A (2012)	1
RCC1	2	RAN	1	pull down, x-ray crystallography, pull down, two hybrid, pull down, biochemical, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Steggerda SM (2000), Renault L (2001), Azuma Y (1999), Ren M (1995), Dasso M (1994), Bischoff FR (1995), Zhang C (2000), Hitakomate E (2010), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	12
ERBB2	6	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scaltriti M (2009), Shtiegman K (2007), Haslekas C (2005), Riedemann J (2007), Burke P (2001), Meijer IM (2011), Chen TC (2014), Li J (2013), Li J (2013), Caiazza F (2010), Caiazza F (2010), Sharif A (2009)	12
NXF1	0	KPNB1	3	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Zhang ZC (2011), Zhang ZC (2011), Bachi A (2000), Hein MY (2015)	4
NUP107	1	IPO7	3	affinity chromatography technology	Hein MY (2015)	1
IPO8	9	IPO9	8	biochemical	Wan C (2015)	1
KPNA3	0	KPNA4	0	biochemical	Wan C (2015)	1
CFTR	5	TP53	0	affinity chromatography technology	Pankow S (2015)	1
KPNA2	0	KPNA4	0	biochemical, biochemical	Kristensen AR (2012), Wan C (2015)	2
UBE2I	0	NUP98	5	affinity chromatography technology	Hein MY (2015)	1
NUP107	1	NUP50	0	bioid, affinity chromatography technology	Kim DI (2014), Hein MY (2015)	2
KPNB1	3	KPNA2	0	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Nagoshi E (2001), Koehler M (1999), Kutay U (1997), Hein MY (2015), Huttlin EL (2017)	5
NUP107	1	NUP98	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, bioid, affinity chromatography technology	Kaur S (2010), Glavy JS (2007), Glavy JS (2007), Wan C (2015), Kim DI (2014), Hein MY (2015)	6
SELENOS	0	AMFR	2	affinity chromatography technology, affinity chromatography technology	Ballar P (2007), Zhong Y (2011)	2
ERBB2	6	KPNB1	3	affinity chromatography technology, affinity chromatography technology	Giri DK (2005), Giri DK (2005)	2
NUP153	1	NUP98	5	affinity chromatography technology	Hein MY (2015)	1
TP53	0	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SMN1	0	KPNB1	3	affinity chromatography technology, pull down	Narayanan U (2002), Narayanan U (2002)	2
7179	0	SMN1	0	affinity chromatography technology	Yadav L (2017)	1
NUP153	1	KPNA3	0	affinity chromatography technology	Hein MY (2015)	1
NUP107	1	RAN	1	affinity chromatography technology	Hein MY (2015)	1
NUP153	1	IPO7	3	affinity chromatography technology	Hein MY (2015)	1
NUP50	0	RANBP2	9	affinity chromatography technology	Huttlin EL (2015)	1
NUP153	1	UBE2I	0	affinity chromatography technology	Hein MY (2015)	1
RAN	1	KPNA2	0	pull down	Bischoff FR (1997)	1
TRIM3	2	NOTCH1	25	affinity chromatography technology	Mukherjee S (2016)	1
PTHLH	0	KPNB1	3	pull down, x-ray crystallography, pull down	Cingolani G (2002), Cingolani G (2002), Lam MH (2001)	3
PPP1CC	2	KPNB1	3	affinity chromatography technology, bioid	Yadav L (2017), Yadav L (2017)	2
NUSAP1	0	IPO7	3	affinity chromatography technology	Huttlin EL (2015)	1
PPP1CC	2	TP53	0	affinity chromatography technology	Flores-Delgado G (2007)	1
NUP50	0	KPNB1	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lindsay ME (2002), Lindsay ME (2002), Hein MY (2015), Huttlin EL (2017)	4
PPM1D	11	NUP153	1	affinity chromatography technology	St-Denis N (2016)	1
NUP153	1	KPNA6	1	affinity chromatography technology	Hein MY (2015)	1
RAN	1	DLGAP5	2	affinity chromatography technology	Huttlin EL (2017)	1
SMAD3	1	NOTCH1	25	pull down, affinity chromatography technology	Blokzijl A (2003), Blokzijl A (2003)	2
CFTR	5	AMFR	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Morito D (2008), Ballar P (2010), Pankow S (2015)	3
NXF1	0	NUP98	5	pull down, affinity chromatography technology, pull down, pull down	Schmitt I (2001), Bachi A (2000), Levesque L (2006), Herold A (2000)	4
PPP1CC	2	NUP50	0	affinity chromatography technology, bioid	Yadav L (2017), Yadav L (2017)	2
NUP85	6	KPNB1	3	bioid, affinity chromatography technology	Kim DI (2014), Hein MY (2015)	2
CFTR	5	EGFR	5	affinity chromatography technology	Pankow S (2015)	1
NUP107	1	UBE2I	0	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
RCC1	2	RANBP2	9	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
KPNB1	3	NUP62	1	pull down, pull down, affinity chromatography technology	Ben-Efraim I (2001), Percipalle P (1997), Walther TC (2003)	3
KPNB1	3	IPO8	9	pull down, biochemical	Goerlich D (1997), Wan C (2015)	2
NUSAP1	0	KPNB1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015)	2
NUP50	0	RANBP1	0	biochemical	Wan C (2015)	1
KPNA2	0	NUP62	1	two hybrid	Rolland T (2014)	1
KPNA4	0	KPNB1	3	pull down, affinity chromatography technology, affinity chromatography technology	Koehler M (1999), Hein MY (2015), Mukherjee S (2016)	3
UBE2I	0	RAN	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
NXF1	0	RANBP2	9	affinity chromatography technology, pull down, biochemical	Bachi A (2000), Levesque L (2006), Wan C (2015)	3
PPM1D	11	KPNA3	0	affinity chromatography technology	St-Denis N (2016)	1
NUP153	1	RAN	1	pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Nakielny S (1999), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	4
IPO5	0	NUP153	1	pull down	Yaseen NR (1997)	1
UBE2I	0	CFTR	5	enzymatic study, enzymatic study	Ahner A (2013), Gong X (2016)	2
UBE2I	0	NXF1	0	affinity chromatography technology	Hein MY (2015)	1
CFTR	5	RANBP2	9	affinity chromatography technology	Pankow S (2015)	1
RANBP2	9	TP53	0	enzymatic study	Gareau JR (2012)	1
NUP107	1	NXF1	0	affinity chromatography technology	Hein MY (2015)	1
NXF1	0	IPO8	9	affinity chromatography technology	Castello A (2012)	1
CFTR	5	KPNA6	1	affinity chromatography technology	Pankow S (2015)	1
KPNB1	3	IPO9	8	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
NUSAP1	0	NUP153	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TP53	0	KPNB1	3	affinity chromatography technology, pull down	Akakura S (2001), Akakura S (2001)	2
EGFR	5	NUP153	1	affinity chromatography technology	Tong J (2014)	1
KPNA6	1	KPNA2	0	biochemical, biochemical	Kristensen AR (2012), Wan C (2015)	2
NUP107	1	KPNB1	3	affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Walther TC (2003), Kim DI (2014), Hein MY (2015), Hein MY (2015)	4
NUP62	1	RANBP2	9	pull down, affinity chromatography technology	Stochaj U (2006), Stochaj U (2006)	2
TP53	0	TAF10	0	affinity chromatography technology	Gamper AM (2008)	1
PPP1CC	2	KPNA2	0	affinity chromatography technology, bioid	Yadav L (2017), Yadav L (2017)	2
RANBP1	0	KPNB1	3	pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, pull down, affinity chromatography technology	Yaseen NR (1999), Plafker K (2000), Plafker K (2000), Ciciarello M (2010), Hieda M (1999), Chi NC (1996), Chi NC (1996), Chi NC (1997), Hein MY (2015)	9
KPNB1	3	RAN	1	far western blotting, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Kutay U (1997), Percipalle P (1997), Plafker K (2000), Ciciarello M (2010), Hieda M (1999), Hieda M (1999), Kutay U (2000), Kutay U (2000), Chi NC (1996), Chi NC (1996), Lipowsky G (2000), Chi NC (1997), Havugimana PC (2012), Goerlich D (1997), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	17
NUP50	0	KPNA6	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	3
KPNA6	1	IPO5	0	biochemical	Wan C (2015)	1
KPNA3	0	KPNB1	3	pull down, pull down, affinity chromatography technology	Koehler M (1999), Nachury MV (1998), Hein MY (2015)	3
UBE2I	0	RCC1	2	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
SELENOS	0	KPNB1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Zhong Y (2011), Zhong Y (2011), Zhong Y (2011), Zhong Y (2011)	4
ING1	2	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Leung KM (2002), Garkavtsev I (1998), Zhu Z (2009)	3
NXF1	0	NUP62	1	pull down, pull down, two hybrid, pull down, two hybrid	Levesque L (2006), Levesque L (2006), Rolland T (2014), Herold A (2000), Yu H (2011)	5
RANBP2	9	RAN	1	pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Yaseen NR (1999), Liu C (2010), Yokoyama N (1995), Yokoyama N (1995), Wang J (2011), Nishitani H (2001), Wan C (2015), Huttlin EL (2017)	8
IPO5	0	KPNA1	5	biochemical, affinity chromatography technology	Wan C (2015), Ross AE (2003)	2
RAN	1	IPO9	8	biochemical, affinity chromatography technology	Wan C (2015), Huttlin EL (2017)	2
KPNA3	0	IPO9	8	biochemical	Wan C (2015)	1
KPNB1	3	IPO5	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
KPNA4	0	TP53	0	affinity chromatography technology, pull down	Marchenko ND (2010), Marchenko ND (2010)	2
KPNA1	5	RAN	1	biochemical	Wan C (2015)	1
RAN	1	RANBP1	0	two hybrid, pull down, pull down, pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, two hybrid, pull down, biochemical, x-ray crystallography, biochemical	Ren M (1995), Steggerda SM (2000), Steggerda SM (2000), Ren M (1995), Plafker K (2000), Zolotukhin AS (1997), Bischoff FR (1995), Bompard G (2010), De Luca A (2003), Yokoyama N (1995), Kuhlmann J (1997), Havugimana PC (2012), Seewald MJ (2002), Wan C (2015)	14
EGFR	5	IPO7	3	affinity chromatography technology	Foerster S (2013)	1
TP53	0	RAE1	0	affinity chromatography technology	Fogeron ML (2013)	1
KPNB1	3	DCAF8	1	affinity chromatography technology, affinity chromatography technology	Wu F (2012), Wu F (2012)	2
NUP107	1	RANBP2	9	bioid, affinity chromatography technology	Kim DI (2014), Hein MY (2015)	2
EGFR	5	IPO8	9	affinity chromatography technology	Foerster S (2013)	1
EGFR	5	IPO5	0	affinity chromatography technology	Foerster S (2013)	1
CFTR	5	KPNA2	0	affinity chromatography technology	Pankow S (2015)	1
TRIM3	2	KPNA4	0	affinity chromatography technology	Mukherjee S (2016)	1
RANBP2	9	KPNA1	5	pull down	Yaseen NR (1999)	1
UBE2I	0	NUP85	6	affinity chromatography technology	Hein MY (2015)	1
UBE2I	0	TP53	0	two hybrid, two hybrid, two hybrid, enzymatic study, two hybrid, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Minty A (2000), Gallagher WM (1999), Shen Z (1996), Bernier-Villamor V (2002), Wang J (2008), Spektor TM (2011), Jakobs A (2007), Mohideen F (2009), Lin JY (2004), Bennett RL (2012), Heo KS (2013), Morimoto M (2003), Rodriguez MS (1999), Muller S (2000), Fernandez-Lloris R (2006), Mohan RD (2007), Brandt M (2013), Weger S (2005)	18
NXF1	0	NUP153	1	pull down, affinity chromatography technology	Herold A (2000), Hein MY (2015)	2
NUSAP1	0	RANBP2	9	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
KPNA6	1	RAN	1	biochemical	Wan C (2015)	1
NUP107	1	NUP153	1	biochemical, biochemical, bioid, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Kim DI (2014), Hein MY (2015), Hein MY (2015)	5
PPP1CB	9	PPP1CC	2	biochemical, affinity chromatography technology	Wan C (2015), Huttlin EL (2017)	2
DLGAP5	2	KPNB1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015), Yadav L (2017)	3
UBE2I	0	RANBP2	9	affinity chromatography technology, pull down, two hybrid, pull down, x-ray crystallography, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Zhang H (2002), Bandyopadhyay S (2010), Werner A (2012), Tatham MH (2005), Saitoh H (2002), Saitoh H (2002), Gareau JR (2012), Hein MY (2015), Sarkar K (2015), Huttlin EL (2017)	11
NUP98	5	KPNB1	3	pull down, pull down, pull down, biochemical, affinity chromatography technology	Moroianu J (1997), Bonifaci N (1997), Schmidt HB (2015), Wan C (2015), Hein MY (2015)	5
NUP50	0	NUP153	1	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Smitherman M (2000), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
CFTR	5	RAN	1	affinity chromatography technology	Wang X (2006)	1
NUP107	1	RCC1	2	affinity chromatography technology	Hein MY (2015)	1
TP53	0	EGFR	5	genetic interference, genetic interference	Xie L (2013), Ye H (2016)	2
RAN	1	IPO7	3	affinity chromatography technology, affinity chromatography technology, pull down, biochemical	Kutay U (2000), Lipowsky G (2000), Goerlich D (1997), Wan C (2015)	4
RANBP2	9	NUP153	1	affinity chromatography technology, affinity chromatography technology	Yokoyama N (1995), Hein MY (2015)	2
CFTR	5	IPO9	8	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
NUP153	1	KPNA4	0	affinity chromatography technology	Hein MY (2015)	1
PPM1D	11	RANBP2	9	affinity chromatography technology	St-Denis N (2016)	1
RANBP1	0	RCC1	2	biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2015), Huttlin EL (2017)	3
CFTR	5	IPO8	9	affinity chromatography technology	Pankow S (2015)	1
KPNA6	1	KPNB1	3	pull down, biochemical, affinity chromatography technology	Koehler M (1999), Havugimana PC (2012), Hein MY (2015)	3
NUP107	1	KPNA4	0	affinity chromatography technology	Hein MY (2015)	1
CFTR	5	TAF10	0	affinity chromatography technology	Pankow S (2015)	1
PPM1D	11	KPNA6	1	affinity chromatography technology	Yadav L (2017)	1
UBE2I	0	KPNB1	3	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2