Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
AQP1 358 DIMETHYL SULFOXIDE CHEMBL504 NCI 9374641
AQP1 358 CHEMBL395336 CHEMBL395336 activator GuideToPharmacologyInteractions
AQP1 358 SILVER CHEMBL1230866 inhibitor GuideToPharmacologyInteractions
AQP1 358 ACETAZOLAMIDE CHEMBL20 NCI 12147198
AQP1 358 GLYBURIDE CHEMBL472 NCI 14759764

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
AQP1 rs28362731 AG cisplatin efficacy no No significant association between genotype and progress-free survival, overall survival or chemotherapy response in patients with malignant mesothelioma who were treated with cisplatin-based chemotherapy. Genotype AG is not associated with response to cisplatin in people with Mesothelioma as compared to genotype GG. 30840592 1450936460
AQP1 rs1049305 CC + CG cisplatin efficacy no No significant association between genotype and progress-free survival, overall survival or chemotherapy response in patients with malignant mesothelioma who were treated with cisplatin-based chemotherapy. Genotypes CC + CG are not associated with response to cisplatin in people with Mesothelioma as compared to genotype GG. 30840592 1450936468