PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
PELO	1	FANCI	1	affinity chromatography technology	Ewing RM (2007)	1
POLN	4	RBBP8	1	affinity chromatography technology	Takata K (2015)	1
MRPL22	0	WDR61	0	genetic interference	Horlbeck MA (2018)	1
POLN	4	SNAPC1	0	genetic interference	Horlbeck MA (2018)	1
ACTR10	0	PPP2R1A	8	genetic interference	Horlbeck MA (2018)	1
CDC27	2	CDC23	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Lara-Gonzalez P (2011), Tran K (2008), Dube P (2005), Fehr AR (2012), Holzmann J (2011), Lee SJ (2012), Hayes MJ (2006), Havugimana PC (2012), Vodermaier HC (2003), Tran K (2010), Wan C (2015), Hein MY (2015), Qiao R (2016), Qiao R (2016), Boldt K (2016)	18
BARD1	4	BRIP1	2	unspecified method, affinity chromatography technology	Thanassoulas A (2010), Wu W (2016)	2
HELQ	4	FANCI	1	affinity chromatography technology	Adelman CA (2013)	1
POLN	4	PALB2	3	affinity chromatography technology	Takata K (2015)	1
PELO	1	POLN	4	genetic interference	Horlbeck MA (2018)	1
FANCD2	3	RAD51	3	affinity chromatography technology, biochemical, imaging technique, pull down	Chen X (2016), Chen X (2016), Sato K (2016), Sato K (2016)	4
FANCD2	3	BRCA1	7	two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Reuter TY (2003), Vandenberg CJ (2003), Garcia-Higuera I (2001), Garcia-Higuera I (2001), Loke J (2015)	5
POLN	4	BRCA2	6	affinity chromatography technology	Takata K (2015)	1
BARD1	4	RAD51	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dong Y (2003), Dong Y (2003), Hu Y (2014)	3
RBBP8	1	FANCD2	3	affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, pull down, pull down, affinity chromatography technology, genetic interference, imaging technique, affinity chromatography technology	Yeo JE (2014), Murina O (2014), Murina O (2014), Murina O (2014), Murina O (2014), Murina O (2014), Unno J (2014), Unno J (2014), Unno J (2014), Unno J (2014), Unno J (2014), Unno J (2014)	12
ARL2	0	CENPW	1	genetic interference	Horlbeck MA (2018)	1
POLN	4	FANCA	5	affinity chromatography technology	Moldovan GL (2010)	1
ACTR10	0	POLN	4	genetic interference	Horlbeck MA (2018)	1
POLN	4	POLDIP2	1	pull down, two hybrid	Tissier A (2010), Tissier A (2010)	2
FANCA	5	FANCD2	3	affinity chromatography technology, affinity chromatography technology	Huard CC (2013), Huard CC (2013)	2
FANCD2	3	POLN	4	imaging technique, affinity chromatography technology	Park HK (2010), Moldovan GL (2010)	2
ELP4	2	POLN	4	genetic interference	Horlbeck MA (2018)	1
PALB2	3	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang F (2009), Sy SM (2009), Zhang F (2009), Zhang F (2009), Zhang F (2009), Sy SM (2009), Sy SM (2009), Sy SM (2009), Sy SM (2009), Sy SM (2009), Zhang F (2012), Johnson N (2013), Anantha RW (2013), Hill SJ (2014), Bleuyard JY (2012), Orthwein A (2015), Orthwein A (2015), Loke J (2015), Simhadri S (2014), Ma J (2012), Ma J (2012), Foo TK (2017)	22
ATR	6	FANCI	1	enzymatic study	Shigechi T (2012)	1
BRCA1	7	PCNA	0	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
BRCA1	7	RAD51	3	pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scully R (1997), Dong Y (2003), Dong Y (2003), Dong Y (2003), Wang Q (2001), Chen J (1998), Mok MT (2010), Scully R (1997), Scully R (1997), Johnson N (2013), Jung YS (2014), Jung YS (2014), Parameswaran B (2015)	13
POLN	4	BARD1	4	affinity chromatography technology	Takata K (2015)	1
BRCA2	6	PCNA	0	affinity chromatography technology	Brough R (2012)	1
BRCA1	7	RAD18	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian F (2013), Tian F (2013), Hill SJ (2014)	3
MRPL22	0	POLN	4	genetic interference	Horlbeck MA (2018)	1
RAD51	3	FANCI	1	pull down	Sato K (2016)	1
BARD1	4	WDR61	0	two hybrid	Woods NT (2012)	1
RAD51	3	FANCA	5	affinity chromatography technology	Karras GI (2017)	1
CDC27	2	WDR61	0	genetic interference	Horlbeck MA (2018)	1
FANCD2	3	BRCA2	6	imaging technique, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Wang X (2004), Wang X (2004), Hussain S (2004), Hussain S (2004), Hejna J (2008), Wilson JB (2010), Wilson JB (2010), Wilson JB (2008), Wilson JB (2008), Wang X (2004), Zhi G (2009), Zhi G (2009), Siddiqui MQ (2017), Siddiqui MQ (2017), Siddiqui MQ (2017)	15
CDC23	3	WDR61	0	genetic interference	Horlbeck MA (2018)	1
BRCA2	6	BARD1	4	pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Dong Y (2003), Dong Y (2003), Ryser S (2009), Ryser S (2009), Kumaraswamy E (2007), Greenberg RA (2006)	6
RAD51	3	RAD18	3	affinity chromatography technology, pull down, affinity chromatography technology	Huang J (2009), Huang J (2009), Chen X (2016)	3
FANCA	5	FANCG	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, biochemical, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Garcia-Higuera I (1999), Park SJ (2004), Garcia-Higuera I (1999), Yagasaki H (2001), Gordon SM (2003), Park SJ (2004), Garcia-Higuera I (1999), Huber PA (2000), Kruyt FA (1999), Kruyt FA (1999), Reuter T (2000), Blom E (2004), Thomashevski A (2004), Waisfisz Q (1999), Waisfisz Q (1999), Gordon SM (2003), Meetei AR (2003), Taniguchi T (2002), Taniguchi T (2002), Otsuki T (2002), Medhurst AL (2001), Medhurst AL (2001), Medhurst AL (2001), Garcia-Higuera I (2000), Yan Z (2010), Taniguchi T (2003), Wilson JB (2010), Wilson JB (2010), Singh TR (2010), Collins NB (2009), Tremblay CS (2008), Wilson JB (2008), Jacquemont C (2007), Ling C (2007), Ling C (2007), Ciccia A (2007), Medhurst AL (2006), Hussain S (2006), Mi J (2004), Mi J (2004), Qiao F (2004), Qiao F (2004), Ferrer M (2004), Thomashevski A (2004), Meetei AR (2003), Meetei AR (2003), Adachi D (2002), Meetei AR (2003), Nakanishi K (2001), Qiao F (2001), Futaki M (2001), Xie Y (2000), Ren J (2001), de Winter JP (2000), Kuang Y (2000), Kuang Y (2000), Kuang Y (2000), Kuang Y (2000), Garcia-Higuera I (1999), Huang M (2011), Yan Z (2012), Yan Z (2012), Huang Y (2014), Huang Y (2014), Zhu B (2014), Ali AM (2012), Ali AM (2012), Ali AM (2012), Huttlin EL (2017), Tremblay CS (2009), Huard CC (2013), Karras GI (2017)	73
BRCA2	6	RAD51	3	two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Sharan SK (1997), Lin HR (2003), Yu DS (2003), Yu DS (2003), Chen PL (1998), Chen PL (1998), Chen PL (1998), Dong Y (2003), Dong Y (2003), Dong Y (2003), Sarkisian CJ (2001), Wong AK (1997), Wong AK (1997), Katagiri T (1998), Katagiri T (1998), Pellegrini L (2002), Tarsounas M (2004), Liu J (2001), Chen J (1998), Sharan SK (1997), Marmorstein LY (1998), Ohashi A (2005), Shivji MK (2006), Xia B (2006), Xia B (2006), Badie S (2010), Liu J (2010), Carreira A (2011), Chen CF (1999), Chen CF (1999), Chen CF (1999), Lee M (2011), Esashi F (2005), Esashi F (2005), Esashi F (2005), Thorslund T (2007), Thorslund T (2007), Esashi F (2007), Brough R (2012), Zhao W (2015), Chu WK (2015), Trego KS (2016), Trego KS (2016), Trego KS (2016), Trego KS (2016), Luo K (2016)	46
ATR	6	BRCA2	6	unspecified method	Kim ST (1999)	1
BRCA2	6	FANCG	3	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Hussain S (2003), Hussain S (2003), Wilson JB (2010), Wilson JB (2010), Wilson JB (2008), Hussain S (2006), Hussain S (2006), Hussain S (2006)	8
CIT	14	POLN	4	genetic interference	Horlbeck MA (2018)	1
FANCD2	3	RAD18	3	affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, biochemical	Williams SA (2011), Williams SA (2011), Park HK (2010), Chen X (2016), Chen X (2016)	5
BRIP1	2	FANCD2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down	Clark DW (2015), Clark DW (2015), Chen X (2014), Chen X (2014), Chen X (2014)	5
POLN	4	PPP2R1A	8	genetic interference	Horlbeck MA (2018)	1
BRCA2	6	BRCA1	7	affinity chromatography technology, two hybrid, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sarkisian CJ (2001), Reuter TY (2003), Dong Y (2003), Chen J (1998), Chen J (1998), Villarroel MC (2011), Kumaraswamy E (2007), Sy SM (2009), Sy SM (2009), Sy SM (2009), Johnson N (2013), Hill SJ (2014), Loke J (2015)	13
FANCD2	3	FANCG	3	affinity chromatography technology	Wilson JB (2008)	1
PCNA	0	FANCD2	3	affinity chromatography technology, affinity chromatography technology, pull down, biochemical	Howlett NG (2009), Howlett NG (2009), Howlett NG (2009), Chen X (2016)	4
FANCI	1	FANCD2	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, imaging technique, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, pull down, pull down, affinity chromatography technology, two hybrid, two hybrid	Yuan F (2009), Ishiai M (2008), Sims AE (2007), Rego MA (2012), Longerich S (2014), Polito D (2014), Wang D (2016), Oka Y (2015), Oka Y (2015), Oka Y (2015), Oka Y (2015), Unno J (2014), Long DT (2011), Sato K (2014), Sato K (2014), Takahashi D (2014), Gwon GH (2014), Lossaint G (2013), Siddiqui MQ (2017), Inano S (2017)	20
BRIP1	2	BRCA1	7	affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, unspecified method, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, unspecified method, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Botuyan MV (2004), Botuyan MV (2004), Botuyan MV (2004), Joo WS (2002), Yu X (2003), Yu X (2003), Rodriguez M (2003), Rodriguez M (2003), Clapperton JA (2004), Clapperton JA (2004), Yu X (2003), Kim H (2007), Sobhian B (2007), Suhasini AN (2011), Xie J (2010), Peng M (2007), Peng M (2007), Gupta R (2007), Nelson AC (2010), Nelson AC (2010), Nomine Y (2008), Dohrn L (2012), Drikos I (2009), Tischkowitz M (2008), Campbell SJ (2010), Hill SJ (2014), Wu W (2016), Suhasini AN (2013), Sakasai R (2012), Guo M (2014), Ertych N (2016)	31
PALB2	3	RBBP8	1	affinity chromatography technology	Sy SM (2009)	1
HELQ	4	ATR	6	affinity chromatography technology, affinity chromatography technology	Adelman CA (2013), Adelman CA (2013)	2
PALB2	3	BRCA2	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Hayakawa T (2010), Zhang F (2009), Sy SM (2009), Zhang F (2009), Xia B (2007), Xia B (2006), Xia B (2006), Xia B (2006), Sy SM (2009), Sy SM (2009), Sy SM (2009), Sy SM (2009), Zhang F (2012), Oliver AW (2009), Oliver AW (2009), Oliver AW (2009), Anantha RW (2013), Bleuyard JY (2012), Brough R (2012), Orthwein A (2015), Trego KS (2016), Trego KS (2016), Trego KS (2016), Simhadri S (2014), Byrd PJ (2016), Park JY (2014), Park JY (2014), Ma J (2012), Ma J (2012), Luijsterburg MS (2017), Luijsterburg MS (2017), Foo TK (2017)	32
PCNA	0	RAD51	3	affinity chromatography technology, imaging technique	Chen X (2016), Sato K (2016)	2
POLN	4	HELQ	4	affinity chromatography technology, affinity chromatography technology	Moldovan GL (2010), Moldovan GL (2010)	2
BRCA1	7	RBBP8	1	unspecified method, two hybrid, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Rodriguez M (2003), Li S (1999), Li S (1999), Li S (1999), Wong AK (1998), Wong AK (1998), Li S (2000), Wu-Baer F (2001), Yu X (1998), Yu X (1998), Yu X (2000), Yu X (2000), Yu X (2000), Kim H (2007), Yu X (2006), Yu X (2006), Wu-Baer F (2010), Volcic M (2012), Wang B (2007), Wang B (2007), Furuta S (2006), Furuta S (2006), Drikos I (2009), Tischkowitz M (2008), Li S (2000), Wu-Baer F (2001), Chen L (2008), Sevcik J (2013), Johnson N (2013), Hill SJ (2014), Cruz-Garcia A (2014), Hu Y (2014), Parameswaran B (2015), Liu H (2015), Renaud E (2016)	35
RBBP8	1	PCNA	0	pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	Gu B (2009), Gu B (2009), Gu B (2009), Gu B (2009)	4
ATR	6	FANCD2	3	enzymatic study, imaging technique, enzymatic study	Ho GP (2006), Pichierri P (2004), Shigechi T (2012)	3
PALB2	3	RAD51	3	pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Dray E (2010), Hayakawa T (2010), Zhang F (2009), Zhang F (2009), Xia B (2006), Anantha RW (2013), Bleuyard JY (2012), Trego KS (2016), Trego KS (2016), Trego KS (2016), Simhadri S (2014), Park JY (2014), Park JY (2014), Ma J (2012), Ma J (2012), Luijsterburg MS (2017), Foo TK (2017), Foo TK (2017)	18
PELO	1	WDR61	0	genetic interference, genetic interference	Horlbeck MA (2018), Horlbeck MA (2018)	2
CDC23	3	POLN	4	genetic interference	Horlbeck MA (2018)	1
PCNA	0	POLDIP2	1	two hybrid, pull down, affinity chromatography technology	Liu L (2003), Liu L (2003), Liu L (2003)	3
ARL2	0	EIF4G2	7	genetic interference	Horlbeck MA (2018)	1
POLN	4	RAD51	3	affinity chromatography technology	Moldovan GL (2010)	1
POLN	4	FANCG	3	affinity chromatography technology	Moldovan GL (2010)	1
EIF4G2	7	POLN	4	genetic interference	Horlbeck MA (2018)	1
ATR	6	POLN	4	enzymatic study	Goehler T (2011)	1
ACTR10	0	CENPW	1	genetic interference	Horlbeck MA (2018)	1
PPP2R1A	8	POLDIP2	1	affinity chromatography technology	Fogeron ML (2013)	1
RAD18	3	PCNA	0	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, enzymatic study, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Song IY (2010), Inagaki A (2011), Kobayashi J (2010), Masuda Y (2010), Watanabe K (2004), Watanabe K (2004), Watanabe K (2004), Notenboom V (2007), Notenboom V (2007), Wong RP (2011), Masuda Y (2012), Unk I (2006), Tomida J (2008), Durando M (2013), Han J (2014), Han J (2014), Han J (2014), Masuda Y (2012), Masuda Y (2015), Guan J (2017)	20
ATR	6	FANCA	5	enzymatic study	Collins NB (2009)	1
POLN	4	WDR61	0	genetic interference	Horlbeck MA (2018)	1
CIT	14	PPP2R1A	8	genetic interference	Horlbeck MA (2018)	1
CDC27	2	POLN	4	genetic interference	Horlbeck MA (2018)	1
EIF4G2	7	RAD51	3	genetic interference	Horlbeck MA (2018)	1
ARL2	0	CDC27	2	genetic interference	Horlbeck MA (2018)	1
BARD1	4	RBBP8	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu X (2000), Greenberg RA (2006), Greenberg RA (2006), Greenberg RA (2006), Wu-Baer F (2010), Coleman KA (2011), Hu Y (2014)	7
ARL2	0	CDC23	3	genetic interference	Horlbeck MA (2018)	1
PCNA	0	FANCA	5	affinity chromatography technology	Geng L (2010)	1
POLN	4	BRIP1	2	affinity chromatography technology, affinity chromatography technology	Takata K (2015), Takata K (2015)	2
RAD18	3	FANCI	1	imaging technique	Williams SA (2011)	1
CDC27	2	CENPW	1	genetic interference	Horlbeck MA (2018)	1
HELQ	4	FANCD2	3	affinity chromatography technology, affinity chromatography technology	Adelman CA (2013), Adelman CA (2013)	2
ARL2	0	POLN	4	genetic interference	Horlbeck MA (2018)	1
PPP2R1A	8	RAD51	3	genetic interference	Horlbeck MA (2018)	1
ARL2	0	PPP2R1A	8	genetic interference	Horlbeck MA (2018)	1
CDC27	2	PCNA	0	affinity chromatography technology	Williamson A (2011)	1
MRPL22	0	SNAPC1	0	genetic interference	Horlbeck MA (2018)	1
POLN	4	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, imaging technique	Moldovan GL (2010), Bi X (2006), Barkley LR (2012), Park JM (2014), Park JM (2014)	5
POLN	4	RAD18	3	affinity chromatography technology, affinity chromatography technology	Bi X (2006), Barkley LR (2012)	2
POLN	4	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Takata K (2015), Takata K (2015), Takata K (2015)	3
ARL2	0	WDR61	0	genetic interference	Horlbeck MA (2018)	1
BRCA1	7	BARD1	4	two hybrid, two hybrid, pull down, pull down, pull down, pull down, imaging technique, imaging technique, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, two hybrid, pull down, pull down, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, two hybrid, x-ray crystallography, imaging technique, imaging technique, two hybrid, affinity chromatography technology, protein complementation assay, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology	Wu LC (1996), Wang Q (2001), Wang Q (2001), Mallery DL (2002), Wu-Baer F (2003), Hashizume R (2001), Fabbro M (2002), Rodriguez JA (2004), Brzovic PS (2003), Nishikawa H (2004), Dong Y (2003), Dong Y (2003), Chiba N (2001), Kleiman FE (2001), Kleiman FE (2001), Kleiman FE (2001), Wu LC (1996), Morris JR (2002), Brzovic PS (2001), Xia Y (2003), Meza JE (1999), Kentsis A (2002), Hashizume R (2001), Fabbro M (2004), Brzovic PS (2001), Yu X (1998), Jin Y (1997), Scully R (1999), Fabbro M (2004), Kleiman FE (1999), Kleiman FE (1999), Tascou S (2003), Brzovic PS (2003), Benezra M (2003), Meza JE (1999), Cantor SB (2001), Wang Q (1998), Ryser S (2009), Ryser S (2009), Nishikawa H (2009), Nishikawa H (2009), Sobhian B (2007), Harte MT (2010), Simons AM (2006), Wei L (2008), Kumaraswamy E (2007), Kumaraswamy E (2007), Dizin E (2010), Dizin E (2010), Greenberg RA (2006), Greenberg RA (2006), Greenberg RA (2006), Zhu Q (2011), Chen A (2002), Chen A (2002), Sy SM (2009), Sy SM (2009), Nelson AC (2010), Nelson AC (2010), Morris JR (2006), Brzovic PS (2001), Mok MT (2010), Au WW (2005), Ayi TC (1998), Choudhury AD (2005), Sarkar M (2008), Sarkar M (2008), Thakar A (2010), Lu Y (2012), Kentsis A (2002), Christou CM (2014), Christou CM (2014), Sevcik J (2013), Johnson N (2013), Matsuzawa A (2014), Matsuzawa A (2014), Hill SJ (2014), Hill SJ (2014), Hill SJ (2014), Starita LM (2015), Hu Y (2014), Wu W (2015), Loke J (2015), Densham RM (2016), Boukerroucha M (2015), Huttlin EL (2017), Liang Y (2017), Liang Y (2017), Liang Y (2017), Ertych N (2016), Ertych N (2016)	91
POLN	4	POLN	4	genetic interference	Horlbeck MA (2018)	1
BRCA1	7	FANCA	5	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Folias A (2002), Folias A (2002), Folias A (2002), Suhasini AN (2011)	4
CDC27	2	SNAPC1	0	genetic interference	Horlbeck MA (2018)	1
FANCI	1	BRCA2	6	two hybrid	Siddiqui MQ (2017)	1
ATR	6	BRCA1	7	pull down, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Tibbetts RS (2000), Kim ST (1999), Mu JJ (2007), Chen J (2000), Chen J (2000), Tibbetts RS (2000), Gatei M (2001), Gatei M (2001), Gatei M (2001), Tian F (2013)	10
POLN	4	FANCI	1	affinity chromatography technology	Moldovan GL (2010)	1
CENPW	1	POLN	4	genetic interference	Horlbeck MA (2018)	1