Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
ICA1	rs62435418	A	tramadol	metabolism/PK	not stated	The A allele was significantly associated with decreased conversion of tramadol to M1 in post-mortem cases in the discovery cohort, but this was not replicated. Note that the authors did not assess the CYP2D6 genotype/phenotype of subjects.	Allele A is associated with decreased metabolism of tramadol as compared to allele G.	30971809	1451101180