PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
PTK2	2	JAK2	1	affinity chromatography technology, affinity chromatography technology	Zhu T (1998), Ryu H (2000)	2
HSP90AA1	7	SKP1	0	pull down	Zhang M (2008)	1
SIRT1	3	HSPA4	3	affinity chromatography technology	Law IK (2009)	1
HDAC1	4	HSPA4	3	affinity chromatography technology, affinity chromatography technology	Johnson CA (2002), Johnson CA (2002)	2
APCS	2	HES1	0	two hybrid	Vinayagam A (2011)	1
ELAVL1	0	PTK2	2	affinity chromatography technology	Abdelmohsen K (2009)	1
FANCL	0	FANCG	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Gurtan AM (2006), Singh TR (2010), Singh TR (2010), Kim JM (2008), Medhurst AL (2006), Huang Y (2014), Ali AM (2012), Ali AM (2012)	8
FANCA	5	FANCE	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Meetei AR (2003), Taniguchi T (2002), Taniguchi T (2002), Medhurst AL (2001), Medhurst AL (2001), Medhurst AL (2001), Pace P (2002), Tremblay CS (2008), Ling C (2007), Mosedale G (2005), Leveille F (2004), Thomashevski A (2004), Meetei AR (2003), Meetei AR (2003), Yan Z (2012), Polito D (2014), Ali AM (2012), Huard CC (2013), Huard CC (2013), Huard CC (2014)	20
NHLH2	0	HES1	0	affinity chromatography technology, pull down, pull down, genetic interference	Isogai E (2011), Isogai E (2011), Isogai E (2011), Isogai E (2011)	4
TLE1	6	HDAC1	4	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ahn JW (2009), Ahn JW (2009), Su L (2012), Su L (2012)	4
FANCE	6	FANCG	3	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taniguchi T (2002), Taniguchi T (2002), Medhurst AL (2001), Medhurst AL (2001), Medhurst AL (2001), Pace P (2002), Leveille F (2004), Polito D (2014)	8
HES1	0	HES1	0	affinity chromatography technology	Tremblay CS (2009)	1
FANCC	0	HSPA4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Zhang X (2004), Pang Q (2001), Pang Q (2001), Pang Q (2001)	4
HES1	0	CUL1	7	affinity chromatography technology, affinity chromatography technology	Chen F (2017), Chen F (2017)	2
HSP90AA1	7	STAT3	0	affinity chromatography technology	Sato N (2003)	1
HSP90AA1	7	PTK2	2	affinity chromatography technology	Taipale M (2012)	1
HDAC1	4	HES1	0	affinity chromatography technology	Shen Q (2005)	1
HES1	0	PARP1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kannan S (2011), Kannan S (2011), Kannan S (2011)	3
HEY2	0	HES1	0	pull down	Iso T (2001)	1
FANCF	1	FANCC	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Leveille F (2004), de Winter JP (2000), Tremblay CS (2008), Kowal P (2007), Medhurst AL (2006), Huard CC (2013), Huard CC (2014)	7
LTBR	0	CSNK1E	0	affinity chromatography technology	Huttlin EL (2015)	1
HSP90AA1	7	HSPA4	3	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Kim TS (2006), Hidalgo-de-Quintana J (2008), Skarra DV (2011), Wan C (2015)	4
CSNK1E	0	HES1	0	two hybrid	Vinayagam A (2011)	1
SIRT1	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Lin Z (2012), Hein MY (2015)	2
HEY1	2	HES1	0	affinity chromatography technology, pull down, pull down	Salat D (2015), Villaronga MA (2010), Lopez-Mateo I (2016)	3
FANCC	0	HES1	0	affinity chromatography technology	Tremblay CS (2008)	1
ELAVL1	0	APH1A	2	affinity chromatography technology	Abdelmohsen K (2009)	1
ELAVL1	0	PARP1	3	affinity chromatography technology	Abdelmohsen K (2009)	1
PTK2	2	STAT3	0	affinity chromatography technology, imaging technique	Ryu H (2000), Chen TC (2014)	2
HSP90AA1	7	SPTAN1	9	affinity chromatography technology	Falsone SF (2005)	1
FANCL	0	FANCF	1	affinity chromatography technology, affinity chromatography technology, imaging technique	Gurtan AM (2006), Medhurst AL (2006), Huang Y (2014)	3
FANCF	1	FANCG	3	affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid	Leveille F (2004), de Winter JP (2000), Gordon SM (2003), Gordon SM (2003), Medhurst AL (2001), Medhurst AL (2001), Medhurst AL (2001), Wilson JB (2010), Wilson JB (2010), Wilson JB (2008), Kowal P (2007), Medhurst AL (2006), Hussain S (2006), Leveille F (2004)	14
FANCC	0	FANCA	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Garcia-Higuera I (1999), Garcia-Higuera I (1999), de Winter JP (2000), Garcia-Higuera I (1999), McMahon LW (1999), Reuter T (2000), Thomashevski A (2004), Meetei AR (2003), Taniguchi T (2002), Otsuki T (2002), Taniguchi T (2003), Du W (2010), Tremblay CS (2008), Tremblay CS (2008), Jacquemont C (2007), Ling C (2007), Medhurst AL (2006), Meetei AR (2005), Zhang X (2004), Thomashevski A (2004), Meetei AR (2003), Meetei AR (2003), Adachi D (2002), Siddique MA (2001), Qiao F (2001), Xie Y (2000), Kuang Y (2000), Kupfer G (1999), Yan Z (2012), Ali AM (2012), Tremblay CS (2009), Huard CC (2013), Huard CC (2013), Karras GI (2017), Yamashita T (1998), Kupfer GM (1997), Kupfer GM (1997)	37
HEY2	0	HEY1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Huang CH (2013), Huang CH (2013), Huttlin EL (2015), Huttlin EL (2017), Villaronga MA (2010), Lopez-Mateo I (2016)	6
HEY2	0	HDAC1	4	pull down	Iso T (2001)	1
HES1	0	STAT3	0	affinity chromatography technology, pull down, enzymatic study	Kamakura S (2004), Kamakura S (2004), Kamakura S (2004)	3
NHLH2	0	LMO3	0	genetic interference	Isogai E (2011)	1
FANCA	5	FANCG	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, biochemical, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Garcia-Higuera I (1999), Park SJ (2004), Garcia-Higuera I (1999), Yagasaki H (2001), Gordon SM (2003), Park SJ (2004), Garcia-Higuera I (1999), Huber PA (2000), Kruyt FA (1999), Kruyt FA (1999), Reuter T (2000), Blom E (2004), Thomashevski A (2004), Waisfisz Q (1999), Waisfisz Q (1999), Gordon SM (2003), Meetei AR (2003), Taniguchi T (2002), Taniguchi T (2002), Otsuki T (2002), Medhurst AL (2001), Medhurst AL (2001), Medhurst AL (2001), Garcia-Higuera I (2000), Yan Z (2010), Taniguchi T (2003), Wilson JB (2010), Wilson JB (2010), Singh TR (2010), Collins NB (2009), Tremblay CS (2008), Wilson JB (2008), Jacquemont C (2007), Ling C (2007), Ling C (2007), Ciccia A (2007), Medhurst AL (2006), Hussain S (2006), Mi J (2004), Mi J (2004), Qiao F (2004), Qiao F (2004), Ferrer M (2004), Thomashevski A (2004), Meetei AR (2003), Meetei AR (2003), Adachi D (2002), Meetei AR (2003), Nakanishi K (2001), Qiao F (2001), Futaki M (2001), Xie Y (2000), Ren J (2001), de Winter JP (2000), Kuang Y (2000), Kuang Y (2000), Kuang Y (2000), Kuang Y (2000), Garcia-Higuera I (1999), Huang M (2011), Yan Z (2012), Yan Z (2012), Huang Y (2014), Huang Y (2014), Zhu B (2014), Ali AM (2012), Ali AM (2012), Ali AM (2012), Huttlin EL (2017), Tremblay CS (2009), Huard CC (2013), Karras GI (2017)	73
HES1	0	JAK2	1	affinity chromatography technology	Kamakura S (2004)	1
HES1	0	FANCG	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tremblay CS (2008), Tremblay CS (2008), Tremblay CS (2008), Tremblay CS (2009)	4
SPTAN1	9	FANCF	1	affinity chromatography technology	Lefferts JA (2009)	1
HES1	0	HSPA4	3	affinity chromatography technology	Tremblay CS (2008)	1
HEY2	0	SIRT1	3	affinity chromatography technology, pull down	Takata T (2003), Takata T (2003)	2
SKP1	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Staropoli JF (2003), Min KW (2003), Lisztwan J (1998), Zheng N (2002), Ohta T (1999), Bloom J (2006), Kumar R (2005), Megumi Y (2005), Wang W (2004), Read MA (2000), Wu K (2000), Tan P (1999), Mao X (2011), Lin HK (2009), Yano H (2008), Banerjee S (2010), Gao D (2010), Chua YS (2011), Zhang M (2008), Winston JT (1999), Latres E (1999), Latres E (1999), Arai T (2003), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), Emberley ED (2012), Bennett EJ (2010), Gastaldello S (2012), Michel JJ (1998), Michel JJ (1998), Michel JJ (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Furukawa M (2000), Furukawa M (2000), Liu J (2002), Liu J (2002), Liu J (2002), Yu ZK (1998), Yu ZK (1998), Postow L (2013), Cordero-Espinoza L (2013), Zhou W (2014), Zhou W (2014), Hao J (2015), Hao J (2015), Han XR (2016), Liu YQ (2015), Gorelik M (2016), Al-Yacoub N (2016), Reiterer V (2017), Hu Y (2017), Hauri S (2016), Reitsma JM (2017), Reitsma JM (2017), Chen F (2017)	59
SIRT1	3	PARP1	3	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Rajamohan SB (2009), Rajamohan SB (2009), Rajamohan SB (2009), Rajamohan SB (2009)	4
FANCG	3	SPTAN1	9	biochemical, two hybrid, affinity chromatography technology	McMahon LW (2001), Lefferts JA (2009), Lefferts JA (2009)	3
FANCA	5	FANCL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Meetei AR (2003), Yan Z (2010), Gurtan AM (2006), Singh TR (2010), Tremblay CS (2008), Kim JM (2008), Ling C (2007), Ling C (2007), Ling C (2007), Ciccia A (2007), Medhurst AL (2006), Meetei AR (2005), Huang M (2011), Yan Z (2012), Ali AM (2012), Ali AM (2012), Jang SW (2016), Takata K (2015)	18
FANCF	1	FANCE	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Leveille F (2004), Pace P (2002), Deans AJ (2009), Kowal P (2007), Gordon SM (2005), Leveille F (2004), Leveille F (2004), Bouffard F (2015)	8
ELAVL1	0	SKP1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
CUL1	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
PARP1	3	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Hassa PO (2005), Hassa PO (2005), Hang CT (2010), Rajamohan SB (2009)	4
CUL1	7	HSPA4	3	affinity chromatography technology, affinity chromatography technology	Oshikawa K (2003), Bennett EJ (2010)	2
FANCC	0	HSP90AA1	7	two hybrid	Reuter TY (2003)	1
CUL1	7	FBXL14	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017), Reitsma JM (2017)	3
CUL1	7	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
ELAVL1	0	YWHAB	1	affinity chromatography technology	Abdelmohsen K (2009)	1
HDAC6	0	GAPDH	0	affinity chromatography technology	Watson GW (2016)	1
PTK2	2	HES1	0	two hybrid	Vinayagam A (2011)	1
ELAVL1	0	HDAC6	0	affinity chromatography technology, affinity chromatography technology	Scott GK (2008), Scott GK (2008)	2
ELAVL1	0	FANCE	6	affinity chromatography technology	Abdelmohsen K (2009)	1
FANCA	5	HSP90AA1	7	two hybrid	Reuter TY (2003)	1
FANCC	0	FANCL	0	affinity chromatography technology, affinity chromatography technology	Tremblay CS (2008), Medhurst AL (2006)	2
HES1	0	TLE2	4	pull down, two hybrid	Grbavec D (1998), Grbavec D (1998)	2
FANCF	1	FANCA	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Leveille F (2004), de Winter JP (2000), Meetei AR (2003), Yan Z (2010), Tumini E (2011), Deans AJ (2009), Tremblay CS (2008), Ling C (2007), Kowal P (2007), Medhurst AL (2006), Meetei AR (2005), Leveille F (2004), Thomashevski A (2004), Meetei AR (2003), Meetei AR (2003), Adachi D (2002), Siddique MA (2001), de Winter JP (2000), Yan Z (2012), Ali AM (2012), Tremblay CS (2009), Huard CC (2013), Huard CC (2014), Karras GI (2017)	24
RUNX2	2	HES1	0	affinity chromatography technology, affinity chromatography technology, imaging technique	Shen Q (2005), Shen Q (2005), Shen Q (2005)	3
HES1	0	HSP90AA1	7	affinity chromatography technology	Tremblay CS (2008)	1
HES1	0	FANCA	5	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tremblay CS (2008), Tremblay CS (2008), Tremblay CS (2008), Tremblay CS (2008), Tremblay CS (2009)	5
HSP90AA1	7	GAPDH	0	affinity chromatography technology, biochemical	Falsone SF (2005), Wan C (2015)	2
ELAVL1	0	CSNK1E	0	affinity chromatography technology	Abdelmohsen K (2009)	1
CUL1	7	SPTAN1	9	affinity chromatography technology	Bennett EJ (2010)	1
JAK2	1	HSP90AA1	7	affinity chromatography technology	Cheng MB (2010)	1
JAK2	1	STAT3	0	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Ram PA (1997), Manea A (2010), Andl CD (2004), Kamakura S (2004), He K (2013), Kucia-Tran JA (2016), M L (2016)	7
HEY1	2	TLE1	6	affinity chromatography technology	Tremblay CS (2009)	1
PTK2	2	GAPDH	0	biochemical	Lim ST (2008)	1
HMGCL	2	HES1	0	two hybrid	Vinayagam A (2011)	1
HES1	0	TLE1	6	pull down, affinity chromatography technology, affinity chromatography technology	Buscarlet M (2008), Tremblay CS (2009), Tremblay CS (2009)	3
ELAVL1	0	HES1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
FBXL14	2	SKP1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Hauri S (2016)	2
HSP90AA1	7	FBXL14	2	affinity chromatography technology	Taipale M (2012)	1
HEY1	2	SKP1	0	affinity chromatography technology	Salat D (2015)	1
TLE1	6	TLE2	4	pull down, pull down, two hybrid	Grbavec D (1998), Grbavec D (1998), Grbavec D (1998)	3
CUL1	7	GAPDH	0	affinity chromatography technology	Bennett EJ (2010)	1
FANCC	0	SPTAN1	9	biochemical, affinity chromatography technology, affinity chromatography technology	McMahon LW (2001), McMahon LW (1999), Lefferts JA (2009)	3
NUDT3	0	HES1	0	two hybrid	Vinayagam A (2011)	1
FBXL14	2	HES1	0	affinity chromatography technology, affinity chromatography technology	Chen F (2017), Chen F (2017)	2
FANCC	0	FANCE	6	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, two hybrid, pull down, imaging technique, pull down, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gordon SM (2003), Leveille F (2004), Gordon SM (2003), Taniguchi T (2002), Medhurst AL (2001), Medhurst AL (2001), Medhurst AL (2001), Pace P (2002), Pace P (2002), Pace P (2002), Tremblay CS (2008), Leveille F (2006), Leveille F (2006), Gordon SM (2005), Gordon SM (2005), Gordon SM (2005), Brodeur I (2004), Polito D (2014), Bouffard F (2015), Huard CC (2013), Huard CC (2013), Huard CC (2014)	22
NR4A1	4	HDAC6	0	affinity chromatography technology	Rambaud J (2009)	1
FANCG	3	FANCC	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Garcia-Higuera I (1999), Tremblay CS (2008), Zhang X (2004), Qiao F (2004), Siddique MA (2001), Nakanishi K (2001), Garcia-Higuera I (1999), Huard CC (2013)	8
ELAVL1	0	HEY1	2	affinity chromatography technology	Abdelmohsen K (2009)	1
HES1	0	SIRT1	3	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Takata T (2003), Takata T (2003), Takata T (2003), Takata T (2003)	4
ELAVL1	0	SIRT1	3	affinity chromatography technology	Abdelmohsen K (2009)	1
ASGR2	1	HES1	0	two hybrid	Wang J (2011)	1
PTK2	2	PARP1	3	biochemical	Lim ST (2008)	1
HES1	0	FANCE	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tremblay CS (2008), Bouffard F (2015), Tremblay CS (2009)	3
FANCA	5	SPTAN1	9	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McMahon LW (2001), McMahon LW (1999), Sridharan D (2003), McMahon LW (1999)	4
GAPDH	0	HES1	0	two hybrid	Vinayagam A (2011)	1
NR4A1	4	STAT3	0	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
SIRT1	3	GAPDH	0	affinity chromatography technology, pull down	Kornberg MD (2010), Kornberg MD (2010)	2
SIRT1	3	TLE1	6	two hybrid, affinity chromatography technology	Ghosh HS (2007), Ghosh HS (2007)	2
HDAC6	0	HES1	0	two hybrid	Vinayagam A (2011)	1
HES1	0	LMO3	0	genetic interference, affinity chromatography technology	Isogai E (2011), Isogai E (2011)	2
HES1	0	SPTAN1	9	affinity chromatography technology	Tremblay CS (2008)	1
ELAVL1	0	NUDT3	0	affinity chromatography technology	Abdelmohsen K (2009)	1
RUNX2	2	TLE1	6	affinity chromatography technology, imaging technique	Ali SA (2010), Ali SA (2010)	2
HES1	0	FANCF	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tremblay CS (2008), Tremblay CS (2008), Tremblay CS (2008), Tremblay CS (2009)	4
YWHAB	1	HES1	0	two hybrid	Vinayagam A (2011)	1
SIRT1	3	STAT3	0	affinity chromatography technology	Lin Z (2012)	1
HES1	0	FANCL	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Tremblay CS (2008), Tremblay CS (2008), Tremblay CS (2008)	3
RUNX2	2	HDAC1	4	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, genetic interference	Lee HW (2006), Zhang Z (2012), Ali SA (2012), Ali SA (2012), Ali SA (2012)	5
HDAC6	0	JAK2	1	affinity chromatography technology	M L (2016)	1
APH1A	2	HES1	0	two hybrid	Wang J (2011)	1
FHL1	1	HES1	0	two hybrid	Vinayagam A (2011)	1
HDAC6	0	STAT3	0	affinity chromatography technology, affinity chromatography technology, imaging technique	M L (2016), M L (2016), M L (2016)	3
ELAVL1	0	STAT3	0	affinity chromatography technology	Abdelmohsen K (2009)	1
HDAC6	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Kekatpure VD (2009), Rao R (2008), Bali P (2005), Kovacs JJ (2005), New M (2013), Rao R (2012), Kovacs JJ (2005)	7
HDAC6	0	HSPA4	3	affinity chromatography technology	New M (2013)	1
HES1	0	LTBR	0	two hybrid	Wang J (2011)	1
APH1A	2	TLE1	6	two hybrid	Wang J (2011)	1
HDAC6	0	RUNX2	2	affinity chromatography technology, affinity chromatography technology	Westendorf JJ (2002), Ozaki T (2013)	2
NR4A1	4	HES1	0	two hybrid	Vinayagam A (2011)	1
HES1	0	SKP1	0	affinity chromatography technology	Chen F (2017)	1
STAT3	0	RUNX2	2	affinity chromatography technology	Fan D (2007)	1
STAT3	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Zhang Q (2005), Yuan ZL (2005), Gupta M (2011), Zhi Y (2012), Zhi Y (2012)	5