PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
UBE2D2	0	LRSAM1	2	two hybrid	Markson G (2009)	1
UBE2K	0	TRIM43	0	two hybrid	Markson G (2009)	1
PRKN	1	UBE2N	1	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down	Joch M (2007), Olzmann JA (2007), Chaugule VK (2011), Sha D (2010), Lim GG (2013), Durcan TM (2011), McKeon JE (2014), Sha D (2010)	8
BARD1	4	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Dong Y (2003), Dong Y (2003), Feki A (2005), Jiang J (2011), Tembe V (2015), Tembe V (2015), Tembe V (2015)	7
TRIM5	4	UBC	7	enzymatic study	Pertel T (2011)	1
LRSAM1	2	RNF111	2	two hybrid	Woodsmith J (2012)	1
UBE2K	0	UHRF2	1	two hybrid	Markson G (2009)	1
RNF2	1	RNF114	0	affinity chromatography technology	Cao Q (2014)	1
UBE2D2	0	RNF4	1	two hybrid, two hybrid, pull down, pull down, pull down, pull down	van Wijk SJ (2009), Markson G (2009), Tatham MH (2013), Erker Y (2013), Banka PA (2015), DiBello A (2016)	6
SMURF1	4	UBE2D2	0	pull down, pull down	Kristariyanto YA (2015), Andrews PS (2010)	2
UHRF2	1	TP53	0	far western blotting, affinity chromatography technology, affinity chromatography technology, pull down	Mori T (2011), Mori T (2011), Mori T (2011), Mori T (2011)	4
RNF2	1	UBE2D2	0	enzymatic study, two hybrid, pull down	Lee SJ (2001), Markson G (2009), Dou H (2012)	3
TP53	0	SENP1	0	affinity chromatography technology	Wu SY (2009)	1
UBE2K	0	MKRN2	2	two hybrid	Markson G (2009)	1
DIABLO	2	UBE2K	0	affinity chromatography technology, pull down, affinity chromatography technology	Bae Y (2010), Bae Y (2010), Bae Y (2010)	3
UBE2V1	0	TRIM5	4	two hybrid	Markson G (2009)	1
PJA1	1	UBE2K	0	pull down	Loch CM (2011)	1
UBE2I	0	TRIM63	0	two hybrid	McElhinny AS (2002)	1
WWP2	7	UBE2K	0	pull down	Sheng Y (2012)	1
DTX3L	1	RNF111	2	two hybrid	Woodsmith J (2012)	1
MAP3K1	4	UBE2K	0	enzymatic study	Charlaftis N (2014)	1
UBE2K	0	RNF2	1	two hybrid, pull down, affinity chromatography technology, two hybrid	Lee SJ (2001), Lee SJ (2001), Lee SJ (2001), Markson G (2009)	4
CCNB1	3	CDC6	0	enzymatic study	Jiang W (1999)	1
UBE2K	0	ITSN1	5	two hybrid	Vinayagam A (2011)	1
UBE2K	0	WDR61	0	biochemical	Havugimana PC (2012)	1
UBE2N	1	TRIM27	2	two hybrid, affinity chromatography technology	Napolitano LM (2011), Napolitano LM (2011)	2
UBE2D2	0	RNF167	2	two hybrid	van Wijk SJ (2009)	1
UBE2V1	0	MID1	1	two hybrid	Markson G (2009)	1
UBE2N	1	SIAH1	2	two hybrid	Markson G (2009)	1
BAG3	4	UBE2K	0	affinity chromatography technology	Chen Y (2013)	1
AMFR	2	UBC	7	pull down, pull down, imaging technique, affinity chromatography technology, enzymatic study, x-ray crystallography, pull down, x-ray crystallography, pull down, enzymatic study, enzymatic study, pull down, affinity chromatography technology	Zhong X (2004), Yang H (2010), Ying Z (2009), Jo Y (2011), Ye Y (2003), Xu Y (2012), Liu S (2012), Liu S (2012), Xu Y (2012), Morito D (2008), Flierman D (2006), Liu W (2014), Fang S (2001)	13
ANAPC11	0	UBE2D2	0	affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Chang TS (2004), Townsend K (2009), Van Voorhis VA (2014), ODonovan KJ (2010), Tang Z (2001), Tang Z (2001), Vodermaier HC (2003), Shoji S (2014), Brown NG (2014), Brown NG (2015)	10
TXN	1	UBE2V1	0	biochemical	Havugimana PC (2012)	1
UBE2D2	0	UBE2V1	0	biochemical	Havugimana PC (2012)	1
PRRG4	1	UBE2K	0	two hybrid	Wang J (2011)	1
UBE2D2	0	RNF185	1	two hybrid	Markson G (2009)	1
FZR1	1	UBE2K	0	pull down	Jin L (2008)	1
UHRF2	1	UBE2I	0	affinity chromatography technology	Oh Y (2013)	1
TMEM189-UBE2V1	0	UBE2K	0	biochemical	Wan C (2015)	1
CDC6	0	UBE2K	0	two hybrid	Wang J (2011)	1
UBE2K	0	DTX3L	1	two hybrid	Markson G (2009)	1
RBCK1	0	UBC	7	affinity chromatography technology, affinity chromatography technology, x-ray crystallography, enzymatic study, pull down, pull down, pull down, pull down, enzymatic study, pull down	Tatematsu K (2008), Yoshimoto N (2009), Sato Y (2011), Kirisako T (2006), Haas TL (2009), Yoshimoto N (2009), Sato Y (2011), Emmerich CH (2013), Emmerich CH (2013), Zhang X (2017)	10
BRCA1	7	UBE2I	0	fluorescent resonance energy transfe, enzymatic study, affinity chromatography technology, affinity chromatography technology	Morris JR (2009), Morris JR (2009), Xu J (2009), Xu J (2009)	4
IQCB1	3	RAB1A	0	affinity chromatography technology	Sang L (2011)	1
TXNDC17	0	UBE2N	1	biochemical	Havugimana PC (2012)	1
SMURF1	4	UBC	7	affinity chromatography technology, enzymatic study, pull down	Xie Y (2013), Kristariyanto YA (2015), Zhang Y (2017)	3
UBE2K	0	HNRNPA1	1	biochemical	Wan C (2015)	1
RNF32	0	MKRN3	2	two hybrid	Woodsmith J (2012)	1
RC3H2	5	UBE2D2	0	pull down	Zhang Q (2015)	1
AMFR	2	UBE2K	0	pull down	Flierman D (2006)	1
MARCH7	0	UBE2D2	0	pull down	Flach K (2014)	1
DLD	1	UBA1	1	affinity chromatography technology	Malty RH (2017)	1
TRAIP	0	RNF114	0	two hybrid	Woodsmith J (2012)	1
UBE2D2	0	RNF125	0	two hybrid	Markson G (2009)	1
TRIM43	0	TRIM27	2	two hybrid	Woodsmith J (2012)	1
AMFR	2	RNF5	0	affinity chromatography technology	Morito D (2008)	1
MDM2	2	UBC	7	pull down, enzymatic study, enzymatic study	Higashitsuji H (2005), Luo J (2013), Poyurovsky MV (2007)	3
UBE2N	1	MKRN3	2	two hybrid	Markson G (2009)	1
BRCA1	7	MKRN2	2	affinity chromatography technology	Ertych N (2016)	1
DLD	1	UBE2K	0	affinity chromatography technology	Malty RH (2017)	1
MAP3K1	4	RNF114	0	enzymatic study	Charlaftis N (2014)	1
UBE2I	0	HNRNPA1	1	biochemical	Wan C (2015)	1
UBE2K	0	BIRC8	0	two hybrid	Markson G (2009)	1
TRAIP	0	UBE2D2	0	pull down	Besse A (2007)	1
TP53	0	UBC	7	affinity chromatography technology, affinity chromatography technology	Ayroldi E (2014), Ke JY (2014)	2
WWP2	7	UBC	7	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Sheng Y (2012), Maspero E (2013), Soond SM (2013), Kristariyanto YA (2015)	4
UBE2V1	0	RNF2	1	two hybrid	Markson G (2009)	1
BRCA1	7	HNRNPL	3	affinity chromatography technology	Ertych N (2016)	1
RNF2	1	TRIM27	2	affinity chromatography technology	Hein MY (2015)	1
CBLC	1	UBE2D2	0	pull down, pull down	Ryan PE (2010), Kim M (2004)	2
RNF4	1	TRAIP	0	two hybrid	Woodsmith J (2012)	1
BRCA1	7	UBE2K	0	two hybrid, x-ray crystallography, pull down, two hybrid, pull down, pull down	Christensen DE (2009), Christensen DE (2009), Christensen DE (2009), Christensen DE (2007), David Y (2011), Shabbeer S (2013)	6
TRIM27	2	PIAS4	5	affinity chromatography technology, two hybrid	Matsuura T (2005), Matsuura T (2005)	2
UBE2D2	0	MARCH3	0	two hybrid	Markson G (2009)	1
UBE2K	0	UBC	7	enzymatic study, x-ray crystallography, x-ray crystallography, pull down, enzymatic study, enzymatic study, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Flierman D (2006), Ko S (2010), Wilson RC (2011), Wilson RC (2011), Wilson RC (2011), Sheng Y (2012), Raasi S (2005), Bishop N (2002), Rajsbaum R (2014), Chong RA (2014), Whitby FG (1998), Singh RK (2012), Cook BW (2015)	13
TRIM5	4	MAP3K1	4	affinity chromatography technology	Pertel T (2011)	1
UBE2V1	0	RNF144A	1	two hybrid	Markson G (2009)	1
HNRNPL	3	ARL15	0	affinity chromatography technology	Fei T (2017)	1
TP53	0	HNRNPL	3	affinity chromatography technology	Horikawa I (2014)	1
MDM2	2	UBE2N	1	pull down	David Y (2011)	1
UBE2K	0	ARL15	0	affinity chromatography technology	Huttlin EL (2017)	1
UBE2K	0	TRIM31	0	two hybrid	Markson G (2009)	1
BRCA1	7	UBE2D2	0	two hybrid, two hybrid, x-ray crystallography, pull down	Dynek JN (2010), Christensen DE (2009), Christensen DE (2009), Christensen DE (2009)	4
FZR1	1	PRKN	1	affinity chromatography technology, affinity chromatography technology	Lee SB (2015), Lee SB (2015)	2
UBE2D2	0	RNF111	2	two hybrid, two hybrid, pull down, pull down, pull down, pull down	van Wijk SJ (2009), Markson G (2009), Erker Y (2013), Wright JD (2016), Birkou M (2017), Birkou M (2017)	6
UBE2K	0	BIRC7	0	two hybrid	Markson G (2009)	1
UBE2K	0	RNF125	0	two hybrid	Markson G (2009)	1
FZR1	1	USP1	4	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Cataldo F (2013), Cotto-Rios XM (2011), Cotto-Rios XM (2011), Cotto-Rios XM (2011)	4
HNRNPL	3	SMURF1	4	affinity chromatography technology	Fei T (2017)	1
UBC	7	PJA1	1	affinity chromatography technology	Matsumoto M (2005)	1
UBE2K	0	RNF167	2	two hybrid	Markson G (2009)	1
UBE2K	0	MKRN3	2	two hybrid	Markson G (2009)	1
UBE2K	0	TRAIP	0	two hybrid	Markson G (2009)	1
UBE2I	0	RC3H2	5	two hybrid	Markson G (2009)	1
SMURF1	4	RNF114	0	enzymatic study	Andrews PS (2010)	1
UBE2N	1	RBCK1	0	two hybrid	Markson G (2009)	1
RC3H2	5	UBC	7	enzymatic study	Zhang Q (2015)	1
UBC	7	HNRNPL	3	affinity chromatography technology	Matsumoto M (2005)	1
ANAPC11	0	UBE2K	0	pull down, pull down, pull down	Bassermann F (2008), Rodrigo-Brenni MC (2007), Van Voorhis VA (2014)	3
UBE2N	1	MARCH7	0	two hybrid, two hybrid, pull down, two hybrid	Markson G (2009), Flach K (2014), Flach K (2014), Nathan JA (2008)	4
TYMS	0	UBE2K	0	biochemical	Havugimana PC (2012)	1
HTT	14	MID1	1	unspecified method	Krauss S (2013)	1
RING1	2	TP53	0	affinity chromatography technology	Calao M (2012)	1
BRCA1	7	UBA1	1	affinity chromatography technology	Ertych N (2016)	1
TXNDC17	0	WDR1	3	biochemical	Havugimana PC (2012)	1
MDM2	2	RNF2	1	affinity chromatography technology, affinity chromatography technology	Wen W (2013), Wen W (2013)	2
TRIM27	2	SIAH1	2	two hybrid	Rolland T (2014)	1
SMURF1	4	UBE2K	0	enzymatic study	Andrews PS (2010)	1
UBE2D2	0	TRIM2	1	two hybrid	Markson G (2009)	1
TRIM34	1	MKRN3	2	two hybrid	Woodsmith J (2012)	1
HNRNPL	3	RNF4	1	affinity chromatography technology	Fei T (2017)	1
UBE2I	0	DTX3L	1	two hybrid	Markson G (2009)	1
BIRC7	0	UBC	7	x-ray crystallography	Dou H (2012)	1
RNF111	2	MARCH7	0	two hybrid	Woodsmith J (2012)	1
BARD1	4	UBE2K	0	pull down	David Y (2011)	1
TXN	1	WDR1	3	biochemical	Havugimana PC (2012)	1
MARCH7	0	UBC	7	enzymatic study	Flierman D (2006)	1
HTT	14	UBE2K	0	two hybrid, two hybrid, pull down, two hybrid	Faber PW (1998), Kalchman MA (1996), Kalchman MA (1996), Suter B (2013)	4
UBE2I	0	RNF111	2	two hybrid, two hybrid, two hybrid	Markson G (2009), Bandyopadhyay S (2010), Rolland T (2014)	3
ZDHHC17	1	UBE2K	0	two hybrid	Butland SL (2014)	1
TRIM39	0	TP53	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhang L (2012), Zhang L (2012), Zhang L (2012)	3
DTX3	4	RNF114	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UBC	7	UBA1	1	affinity chromatography technology, unspecified method, x-ray crystallography, biochemical, affinity chromatography technology, pull down	Nicassio F (2007), Zhao B (2012), Schaefer A (2014), Schaefer A (2014), Bish RA (2007), Zhang X (2017)	6
USP1	4	DTX3	4	two hybrid	Hayes SD (2012)	1
TP53	0	PIAS4	5	two hybrid	Goehler H (2004)	1
BRCA1	7	HNRNPA1	1	affinity chromatography technology	Goina E (2008)	1
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
MAP3K1	4	RBCK1	0	enzymatic study	Charlaftis N (2014)	1
RING1	2	RNF2	1	pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cao R (2005), Gearhart MD (2006), Wang H (2004), Trojer P (2011), Gao Z (2012), Gao Z (2012), Cao Q (2014), Hein MY (2015)	8
CDC6	0	FZR1	1	pull down, enzymatic study, enzymatic study	Ke PY (2004), Petersen BO (2000), Cotto-Rios XM (2011)	3
TRIM31	0	TRIM27	2	two hybrid	Woodsmith J (2012)	1
UBE2K	0	TRAF7	11	two hybrid	Markson G (2009)	1
UBE2K	0	CCNB1	3	affinity chromatography technology	Bae Y (2010)	1
UBE2V1	0	RNF111	2	two hybrid	Markson G (2009)	1
UBE2D2	0	TRAF7	11	two hybrid	Markson G (2009)	1
UBE2N	1	BFAR	0	two hybrid	Markson G (2009)	1
BARD1	4	WDR61	0	two hybrid	Woods NT (2012)	1
AMFR	2	HTT	14	affinity chromatography technology, pull down, pull down	Yang H (2010), Yang H (2010), Yang H (2010)	3
RAB1A	0	HNRNPA1	1	biochemical	Wan C (2015)	1
RNF5	0	RNF185	1	two hybrid	Rolland T (2014)	1
NXF1	0	WWP2	7	affinity chromatography technology	Castello A (2012)	1
UBE2K	0	MARCH7	0	two hybrid, pull down, two hybrid	Markson G (2009), Flierman D (2006), Nathan JA (2008)	3
HTT	14	SIAH1	2	affinity chromatography technology	Bae BI (2006)	1
BARD1	4	UBE2D2	0	pull down	Xia Y (2003)	1
UBE2K	0	RNF111	2	two hybrid	Markson G (2009)	1
UBC	7	NEDD4L	3	x-ray crystallography, enzymatic study, enzymatic study, enzymatic study	Kamadurai HB (2009), Sheng Y (2012), Maspero E (2013), Michel MA (2015)	4
BARD1	4	PRPF40A	5	affinity chromatography technology	Woods NT (2012)	1
UBE2K	0	DZIP3	6	two hybrid	Markson G (2009)	1
ANAPC11	0	RNF111	2	two hybrid	Woodsmith J (2012)	1
NXF1	0	UBE2K	0	affinity chromatography technology	Bachi A (2000)	1
TRIM27	2	MDM2	2	affinity chromatography technology, enzymatic study	Chu Y (2011), Chu Y (2011)	2
UBE2N	1	DZIP3	6	two hybrid	Markson G (2009)	1
TRIM27	2	UHRF2	1	two hybrid	Woodsmith J (2012)	1
UBE2K	0	UBE2N	1	biochemical	Wan C (2015)	1
NEDD4L	3	UBE2K	0	pull down, pull down	Sullivan JA (2007), Sheng Y (2012)	2
UBE2D2	0	CCNB1	3	enzymatic study	Tang Z (2001)	1
SIAH1	2	UBE2I	0	two hybrid, two hybrid	Depaux A (2007), Hu G (1997)	2
BRCA1	7	PIAS4	5	imaging technique, enzymatic study, imaging technique	Galanty Y (2009), Morris JR (2009), Morris JR (2009)	3
SIAH1	2	TXN	1	two hybrid	Wang J (2011)	1
UBE2I	0	MAP3K1	4	two hybrid, pull down, affinity chromatography technology	Saltzman A (1998), Saltzman A (1998), Kubota Y (2011)	3
MAP3K1	4	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Islam MR (2010), Islam MR (2010), Chipps E (2015), Chipps E (2015), Chipps E (2015)	5
UBE2K	0	PIAS4	5	two hybrid	Goehler H (2004)	1
RNF185	1	UBC	7	affinity chromatography technology	Iioka H (2007)	1
UBE2K	0	TRIM39	0	two hybrid, two hybrid	Markson G (2009), Rolland T (2014)	2
UBE2I	0	MDM2	2	pull down, affinity chromatography technology, enzymatic study, unspecified method	Buschmann T (2001), Buschmann T (2001), Buschmann T (2001), Buschmann T (2001)	4
DDX58	3	UBC	7	pull down, pull down	Feng M (2012), Zeng W (2010)	2
UBE2D2	0	TRIM43	0	two hybrid	Markson G (2009)	1
ITCH	1	UBC	7	enzymatic study, unspecified method, enzymatic study, enzymatic study	Sheng Y (2012), Ernst A (2013), Maspero E (2013), Kristariyanto YA (2015)	4
TMEM189-UBE2V1	0	UBE2N	1	biochemical	Wan C (2015)	1
HTT	14	TP53	0	pull down, affinity chromatography technology	Steffan JS (2000), Steffan JS (2000)	2
TXN	1	UBE2K	0	biochemical	Havugimana PC (2012)	1
HTT	14	ITCH	1	imaging technique, affinity chromatography technology, affinity chromatography technology	Chhangani D (2014), Chhangani D (2014), Chhangani D (2014)	3
NUB1	2	UBE2K	0	two hybrid	Tanji K (2006)	1
UBE2N	1	UBA1	1	affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Huen MS (2008), Wu PY (2003), Wauer T (2015), Boldt K (2016)	4
HNRNPL	3	BARD1	4	affinity chromatography technology	Fei T (2017)	1
UBE2D2	0	MKRN3	2	two hybrid	Markson G (2009)	1
UBE2D2	0	TRIM35	1	two hybrid	Markson G (2009)	1
UBE2N	1	RC3H2	5	two hybrid, pull down	Markson G (2009), Zhang Q (2015)	2
UBE2K	0	TRIM2	1	two hybrid	Markson G (2009)	1
BRCA1	7	CCNB1	3	pull down, affinity chromatography technology, enzymatic study	Wang H (1997), Shabbeer S (2013), Shabbeer S (2013)	3
UBE2V1	0	UBC	7	pull down	McKenna S (2003)	1
UBC	7	ANAPC11	0	x-ray crystallography, pull down	Brown NG (2014), Brown NG (2016)	2
UBE2D2	0	TRIM27	2	two hybrid, two hybrid	Markson G (2009), Napolitano LM (2011)	2
BAG3	4	RAB1A	0	affinity chromatography technology	Chen Y (2013)	1
UBA1	1	UBE2D2	0	enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Tokgoez Z (2012), Jin J (2007), Choi JS (2014), Huang DT (2009), Kang D (2002), Kumar B (2010), Liu X (2017), Huguenin-Dezot N (2016)	8
CBLC	1	UBC	7	enzymatic study	Kim M (2004)	1
UBE2K	0	CBLC	1	two hybrid	Markson G (2009)	1
RBCK1	0	UHRF2	1	two hybrid	Woodsmith J (2012)	1
PIAS4	5	PRPF40A	5	two hybrid	Goehler H (2004)	1
RBCK1	0	MKRN2	2	two hybrid	Woodsmith J (2012)	1
HNRNPL	3	MIPOL1	1	affinity chromatography technology	Fei T (2017)	1
PRKN	1	RBCK1	0	two hybrid	Corominas R (2014)	1
ITCH	1	UBE2D2	0	pull down, pull down, pull down, pull down	Sheng Y (2012), Fang S (2001), Kristariyanto YA (2015), Riling C (2015)	4
BRCA1	7	UBE2N	1	two hybrid, x-ray crystallography, pull down, two hybrid, pull down	Christensen DE (2009), Christensen DE (2009), Christensen DE (2009), Christensen DE (2007), David Y (2011)	5
UBE2K	0	MIPOL1	1	two hybrid	Rolland T (2014)	1
HNRNPL	3	PRKN	1	affinity chromatography technology	Fei T (2017)	1
BAG3	4	HTT	14	affinity chromatography technology	Hein MY (2015)	1
UBE2K	0	TRIM35	1	two hybrid	Markson G (2009)	1
FZR1	1	ANAPC11	0	affinity chromatography technology, pull down, unspecified method	Bassermann F (2008), Vodermaier HC (2003), Vodermaier HC (2003)	3
UBE2K	0	PRPF40A	5	two hybrid	Vinayagam A (2011)	1
DTX3L	1	ITCH	1	affinity chromatography technology, pull down, pull down	Holleman J (2014), Holleman J (2014), Holleman J (2014)	3
UBE2K	0	MARCH3	0	two hybrid	Markson G (2009)	1
UBE2D2	0	TRIM39	0	two hybrid, pull down	Markson G (2009), Woodsmith J (2012)	2
UBE2D2	0	AMFR	2	two hybrid, two hybrid, pull down	van Wijk SJ (2009), Markson G (2009), Fang S (2001)	3
WWP2	7	UBE2D2	0	pull down, pull down, pull down	Sheng Y (2012), Kristariyanto YA (2015), Chaudhary N (2014)	3
NXF1	0	DZIP3	6	affinity chromatography technology	Castello A (2012)	1
UBE2V1	0	MKRN3	2	two hybrid	Markson G (2009)	1
UBE2D2	0	RING1	2	two hybrid	Markson G (2009)	1
PIAS4	5	HTT	14	pull down, two hybrid	Goehler H (2004), Goehler H (2004)	2
UBE2K	0	TP53	0	affinity chromatography technology, affinity chromatography technology, protein complementation assay	Bae Y (2013), Bae Y (2013), Bae Y (2013)	3
UBE2K	0	TRIM27	2	two hybrid	Markson G (2009)	1
RC3H2	5	UBE2V1	0	pull down	Zhang Q (2015)	1
DTX3	4	ITSN1	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UBE2D2	0	NEDD4L	3	x-ray crystallography, pull down, pull down, pull down, pull down, pull down, enzymatic study	Kamadurai HB (2009), Isasa M (2010), Sheng Y (2012), Persaud A (2009), Nazio F (2016), Todaro DR (2017), Todaro DR (2017)	7
TRIM63	0	UBE2N	1	pull down	Kim HT (2007)	1
SMURF1	4	TP53	0	affinity chromatography technology	Nie J (2010)	1
DDX58	3	RBCK1	0	affinity chromatography technology	Inn KS (2011)	1
RNF125	0	UBC	7	pull down	Giannini AL (2008)	1
UBC	7	UBE2N	1	affinity chromatography technology, enzymatic study, enzymatic study, x-ray crystallography, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down	Matsumoto M (2005), Scheper J (2010), Wu PY (2003), McKenna S (2003), Wiener R (2012), Ye Y (2003), Bish RA (2007), Juang YC (2012), Pastushok L (2007), Singh RK (2012), McKenna S (2001), McKenna S (2001)	12
UBE2K	0	RING1	2	two hybrid	Markson G (2009)	1
TP53	0	UBE2N	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Laine A (2006), Laine A (2006), Laine A (2006), Topisirovic I (2009), Topisirovic I (2009)	5
UBE2K	0	WDR1	3	biochemical	Havugimana PC (2012)	1
UBE2I	0	RNF4	1	two hybrid, two hybrid	Markson G (2009), Bandyopadhyay S (2010)	2
TRIM35	1	TRIM5	4	pull down	Li X (2006)	1
UBE2K	0	DTX3	4	two hybrid, two hybrid	Markson G (2009), Rolland T (2014)	2
UBE2D2	0	DTX3	4	two hybrid	Markson G (2009)	1
HNRNPL	3	UBE2K	0	affinity chromatography technology	Fei T (2017)	1
SMURF1	4	RBCK1	0	enzymatic study	Andrews PS (2010)	1
SIAH1	2	DLD	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UBE2D2	0	BFAR	0	two hybrid, pull down	Markson G (2009), Rong J (2011)	2
TXNDC17	0	UBE2K	0	biochemical	Havugimana PC (2012)	1
TRIM5	4	MKRN3	2	two hybrid	Woodsmith J (2012)	1
MDM2	2	MKRN3	2	two hybrid	Woodsmith J (2012)	1
SMURF1	4	HNRNPA1	1	affinity chromatography technology	Xie Y (2013)	1
RC3H2	5	UBE2K	0	pull down	Zhang Q (2015)	1
CBLC	1	ITCH	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Courbard JR (2002), Courbard JR (2002), Courbard JR (2002), Courbard JR (2002)	4
UBE2K	0	DDX58	3	enzymatic study	Arimoto K (2008)	1
UBE2I	0	WWP2	7	enzymatic study	Bawa-Khalfe T (2016)	1
UBE2D2	0	TRIM31	0	two hybrid, two hybrid	Markson G (2009), Napolitano LM (2011)	2
UBE2K	0	RNF32	0	two hybrid	Markson G (2009)	1
CBLC	1	TP53	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RNF2	1	SIAH1	2	affinity chromatography technology	Woodsmith J (2012)	1
UBE2K	0	RNF138	0	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Markson G (2009), Yamada M (2006), Yamada M (2006), Rolland T (2014), Huttlin EL (2017), Boldt K (2016)	6
UBE2I	0	UBE2K	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, biochemical	Knipscheer P (2008), Gruenwald M (2011), Pichler A (2005), Galisson F (2011), Wan C (2015)	5
UBE2D2	0	RNF138	0	two hybrid	Markson G (2009)	1
RNF111	2	UBC	7	enzymatic study	Wright JD (2016)	1
UBE2N	1	TRIM5	4	two hybrid, pull down, x-ray crystallography	Markson G (2009), Yudina Z (2015), Yudina Z (2015)	3
TRIM39	0	UBC	7	enzymatic study	Woodsmith J (2012)	1
RNF5	0	UBC	7	enzymatic study	Didier C (2003)	1
USP1	4	UBC	7	enzymatic study, pull down	Faesen AC (2011), Cohn MA (2009)	2
PRKN	1	TXN	1	affinity chromatography technology	Zanon A (2013)	1
SMURF1	4	UBE2V1	0	enzymatic study	Andrews PS (2010)	1
TXN	1	RAB1A	0	biochemical	Wan C (2015)	1
HNRNPL	3	PIAS4	5	affinity chromatography technology	Fei T (2017)	1
UBE2V1	0	UBOX5	4	two hybrid	Markson G (2009)	1
HNRNPL	3	WWP2	7	affinity chromatography technology	Fei T (2017)	1
UBE2K	0	MDM2	2	two hybrid, pull down, pull down	Bae Y (2013), Saville MK (2004), David Y (2011)	3
NXF1	0	UBC	7	affinity chromatography technology	Castello A (2012)	1
BIRC7	0	UBE2I	0	two hybrid, two hybrid	Dynek JN (2010), Dynek JN (2010)	2
UBE2K	0	REL	5	two hybrid	Rolland T (2014)	1
RNF2	1	HNRNPA1	1	affinity chromatography technology	Cao Q (2014)	1
TXN	1	TP53	0	pull down	Stoner CS (2009)	1
UBE2K	0	RNF144A	1	two hybrid	Markson G (2009)	1
TRIM39	0	UBE2N	1	pull down	Woodsmith J (2012)	1
NXF1	0	MKRN2	2	affinity chromatography technology	Huttlin EL (2017)	1
PRKN	1	TP53	0	pull down, enzymatic study	Jung YY (2017), Jung YY (2017)	2
UBE2I	0	UBE2D2	0	biochemical	Wan C (2015)	1
UBE2K	0	RNF185	1	two hybrid, affinity chromatography technology	Markson G (2009), Iioka H (2007)	2
UBE2D2	0	DDX58	3	enzymatic study	Arimoto K (2008)	1
NXF1	0	BAG3	4	affinity chromatography technology	Castello A (2012)	1
BARD1	4	UBE2N	1	pull down	David Y (2011)	1
HNRNPL	3	HTT	14	affinity chromatography technology	Fei T (2017)	1
UBE2K	0	LRSAM1	2	two hybrid	Markson G (2009)	1
UBE2N	1	RNF125	0	two hybrid	Markson G (2009)	1
UBE2N	1	RNF167	2	two hybrid	van Wijk SJ (2009)	1
MDM2	2	SMURF1	4	pull down, affinity chromatography technology, affinity chromatography technology	Nie J (2010), Nie J (2010), Nie J (2010)	3
UBE2I	0	NXF1	0	affinity chromatography technology	Hein MY (2015)	1
HTT	14	ZDHHC17	1	two hybrid, two hybrid, pull down, affinity chromatography technology, two hybrid, two hybrid	Faber PW (1998), Singaraja RR (2002), Singaraja RR (2002), Singaraja RR (2002), Suter B (2013), Butland SL (2014)	6
DIABLO	2	BIRC7	0	affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ma L (2006), Ma L (2006), Vucic D (2002), Shiozaki EN (2003), Ma L (2006), Dou H (2012), Huttlin EL (2015), Liu GH (2015), Huttlin EL (2017)	9
DLD	1	TXN	1	affinity chromatography technology	Malty RH (2017)	1
UBC	7	RNF114	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Matsumoto M (2005), Capon F (2008), Fenner BJ (2009), Fenner BJ (2009)	4
UBE2I	0	CBLC	1	two hybrid	Markson G (2009)	1
UBE2K	0	SIAH1	2	two hybrid, two hybrid	Markson G (2009), Rolland T (2014)	2
RNF5	0	UBE2N	1	pull down	Tcherpakov M (2009)	1
TXN	1	UBE2D2	0	biochemical	Havugimana PC (2012)	1
UBE2V1	0	DTX3	4	two hybrid	Markson G (2009)	1
NEDD4L	3	UBE2N	1	pull down	Herhaus L (2013)	1
UBE2K	0	RNF5	0	two hybrid, two hybrid	Markson G (2009), Rolland T (2014)	2
UBE2V1	0	UBE2K	0	biochemical	Wan C (2015)	1
RNF2	1	HNRNPL	3	affinity chromatography technology	Cao Q (2014)	1
RNF2	1	UBC	7	enzymatic study	Woodsmith J (2012)	1
PRKN	1	CCNB1	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lee SB (2015), Lee SB (2015), Lee SB (2015)	3
UBE2N	1	UBE2V1	0	biochemical, pull down, pull down, pull down, two hybrid, two hybrid, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, two hybrid, biochemical, pull down, pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Deng L (2000), Deng L (2000), Zhang M (2005), Andersen PL (2005), Andersen PL (2005), Scheper J (2010), Scheper J (2010), Scheper J (2010), Wooff J (2004), Plans V (2006), Huen MS (2008), Huen MS (2008), Havugimana PC (2012), Bohgaki M (2008), Petroski MD (2007), Sawasaki T (2008), Wan C (2015), Chen J (2015), Boldt K (2016), Zhang Y (2018)	20
TRIM63	0	UBE2D2	0	pull down	Polge C (2011)	1
NXF1	0	WDR1	3	affinity chromatography technology	Castello A (2012)	1
IQCB1	3	UBE2V1	0	affinity chromatography technology	Sang L (2011)	1
BIRC8	0	DIABLO	2	x-ray crystallography, affinity chromatography technology, affinity chromatography technology	Shin H (2005), Huttlin EL (2015), Huttlin EL (2017)	3
DTX3L	1	UBE2D2	0	affinity chromatography technology, two hybrid, pull down	Takeyama K (2003), Markson G (2009), Yan Q (2009)	3
TRIM63	0	UBE2K	0	pull down	Kim HT (2007)	1
HNRNPA1	1	NXF1	0	affinity chromatography technology	Roy R (2014)	1
UBE2K	0	TRIM5	4	two hybrid	Markson G (2009)	1
UBE2I	0	RNF185	1	two hybrid	Markson G (2009)	1
DLD	1	UBE2N	1	affinity chromatography technology	Malty RH (2017)	1
IQCB1	3	UBE2K	0	affinity chromatography technology	Sang L (2011)	1
ANAPC11	0	CCNB1	3	pull down	Frye JJ (2013)	1
NUB1	2	UBC	7	pull down, affinity chromatography technology	Nakayasu ES (2013), Nakayasu ES (2013)	2
BRCA1	7	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, biochemical, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2004), Ouchi T (1998), Dong Y (2003), Dong Y (2003), Chai YL (1999), Chai YL (1999), Zhang H (1998), Dong Y (2003), Chen Y (2006), Quaresima B (2006), Zhang H (1998), Zhang H (1998), Mark WY (2005), Jin S (2009), Jiang J (2011), Rasti M (2015), Rasti M (2015)	17
HTT	14	PRPF40A	5	two hybrid, pull down, two hybrid	Faber PW (1998), Faber PW (1998), Goehler H (2004)	3
SENP1	0	UBE2K	0	enzymatic study	Galisson F (2011)	1
PIAS4	5	UBE2I	0	two hybrid, pull down, pull down, pull down	Wang J (2011), Yamamoto H (2003), Yin Y (2012), Ryu H (2010)	4
TYMS	0	WDR1	3	biochemical	Havugimana PC (2012)	1
RNF41	2	PRKN	1	enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Yu F (2008), Zhong L (2005), Zhong L (2005), Zhong L (2005), Zhong L (2005)	5
TRAIP	0	UBOX5	4	two hybrid	Woodsmith J (2012)	1
UBC	7	BRCA1	7	pull down, enzymatic study	Sobhian B (2007), Zhao GY (2007)	2
UBE2K	0	BFAR	0	two hybrid	Markson G (2009)	1
PRKN	1	UBE2V1	0	pull down, pull down, pull down, affinity chromatography technology	Chaugule VK (2011), Durcan TM (2011), Sha D (2010), Sha D (2010)	4
FZR1	1	TP53	0	enzymatic study	Gmachl M (2000)	1
UBE2K	0	RNF41	2	two hybrid	Markson G (2009)	1
UBE2N	1	RNF111	2	affinity chromatography technology, pull down	Poulsen SL (2013), Wright JD (2016)	2
UBE2D2	0	RNF114	0	two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study	Markson G (2009), Huttlin EL (2015), Huttlin EL (2017), Lin B (2017)	4
UBE2D2	0	UHRF2	1	two hybrid	van Wijk SJ (2009)	1
RNF2	1	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Calao M (2012), Wen W (2013), Wen W (2013)	3
ITCH	1	UBE2K	0	pull down	Sheng Y (2012)	1
UBE2V1	0	DZIP3	6	two hybrid	Markson G (2009)	1
ITCH	1	ITSN1	5	fluorescent resonance energy transfe, affinity chromatography technology	Desrochers G (2015), Desrochers G (2015)	2
TRIM34	1	TRIM5	4	two hybrid, two hybrid	Zhang F (2006), Woodsmith J (2012)	2
WWP2	7	ITCH	1	affinity chromatography technology	Chaudhary N (2014)	1
TP53	0	RNF125	0	affinity chromatography technology, affinity chromatography technology, pull down	Yang L (2015), Yang L (2015), Yang L (2015)	3
UBE2N	1	MID1	1	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Markson G (2009), Napolitano LM (2011), Napolitano LM (2011), Napolitano LM (2011)	4
RNF144A	1	UBC	7	enzymatic study	Michel MA (2017)	1
BAG3	4	UBE2N	1	affinity chromatography technology	Chen Y (2013)	1
CCNB1	3	FZR1	1	pull down, enzymatic study, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, imaging technique, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Ke PY (2004), Huang NJ (2012), Pfleger CM (2001), Miller JJ (2006), Song MS (2011), Frye JJ (2013), Lau AW (2013), Brown NG (2014), Summers MK (2009), ODonovan KJ (2010), Wu T (2010), Shoji S (2014), Vodermaier HC (2003), Kim HS (2011), Lu L (2013), Yamaguchi M (2015), Brown NG (2015), Chen TC (2014), Williamson A (2011), Qiao R (2016), Brown NG (2016), Huttlin EL (2017)	22
UBE2D2	0	MID1	1	two hybrid, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, pull down	Markson G (2009), Napolitano LM (2011), Napolitano LM (2011), Napolitano LM (2011), Watkins GR (2012), Du H (2014), Schweiger S (2014)	7
FZR1	1	SMURF1	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Kannan M (2012), Kannan M (2012), Wan L (2011), Wan L (2011), Wan L (2011), Wan L (2011)	6
UBE2K	0	DDI1	1	two hybrid	Rolland T (2014)	1
DLD	1	DIABLO	2	affinity chromatography technology	Malty RH (2017)	1
UBE2V1	0	BIRC8	0	two hybrid	Markson G (2009)	1
RNF4	1	UBE2N	1	pull down, x-ray crystallography	Branigan E (2015), Branigan E (2015)	2
DDI1	1	UBC	7	pull down	Raasi S (2005)	1
TXNDC17	0	TYMS	0	biochemical	Havugimana PC (2012)	1
PRKN	1	UBC	7	enzymatic study, imaging technique, enzymatic study, fluorescent resonance energy transfe, pull down, pull down, pull down, pull down, x-ray crystallography, imaging technique, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, enzymatic study, enzymatic study, pull down, x-ray crystallography, enzymatic study	Kondapalli C (2012), Kane LA (2014), Kane LA (2014), Koyano F (2014), Zheng X (2013), Shiba-Fukushima K (2014), Shiba-Fukushima K (2014), Kumar A (2015), Kumar A (2015), Okatsu K (2015), Okatsu K (2015), Okatsu K (2015), Yamano K (2015), Fiesel FC (2015), Ordureau A (2015), Kazlauskaite A (2015), Kazlauskaite A (2015), Kumar A (2017), Kliza K (2017)	19
TP53	0	ITCH	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abedini MR (2008), Saha A (2011), Saha A (2011)	3
UBE2K	0	UBE2D2	0	biochemical	Wan C (2015)	1
UBE2K	0	TRIM34	1	two hybrid	Markson G (2009)	1
USP1	4	UBE2K	0	enzymatic study	Das DS (2017)	1
PRPF40A	5	UBE2I	0	two hybrid	Colland F (2004)	1
TRIM27	2	TP53	0	affinity chromatography technology, pull down, enzymatic study	Chu Y (2011), Chu Y (2011), Chu Y (2011)	3
DLD	1	RAB1A	0	affinity chromatography technology	Malty RH (2017)	1
UBE2I	0	MKRN3	2	two hybrid	Markson G (2009)	1
TP53	0	USP1	4	genetic interference	Xie L (2013)	1
BFAR	0	UBC	7	enzymatic study	Rong J (2011)	1
ITCH	1	UBA1	1	affinity chromatography technology	OConnor HF (2015)	1
TP53	0	NUB1	2	affinity chromatography technology, affinity chromatography technology	Liu G (2010), Liu G (2010)	2
PRKN	1	UBE2K	0	pull down	Kazlauskaite A (2014)	1
UBE2D2	0	DZIP3	6	two hybrid, pull down	Markson G (2009), Zhou W (2008)	2
UBE2K	0	RBCK1	0	two hybrid	Markson G (2009)	1
UBE2K	0	MID1	1	two hybrid	Markson G (2009)	1
BAG3	4	SENP1	0	affinity chromatography technology	Chen Y (2013)	1
MID1	1	UBC	7	affinity chromatography technology, affinity chromatography technology	Trockenbacher A (2001), Trockenbacher A (2001)	2
ZDHHC17	1	DTX3	4	two hybrid	Butland SL (2014)	1
RBCK1	0	UBE2D2	0	pull down	Kirisako T (2006)	1
MAP3K1	4	UBE2V1	0	enzymatic study	Charlaftis N (2014)	1
UBE2N	1	LRSAM1	2	two hybrid, two hybrid, two hybrid	van Wijk SJ (2009), Markson G (2009), Hakonen JE (2017)	3
BIRC7	0	UBE2D2	0	two hybrid, pull down, x-ray crystallography, pull down	Dynek JN (2010), Dou H (2012), Dou H (2012), Ma L (2006)	4
UBE2K	0	CYHR1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
UBE2V1	0	RNF185	1	two hybrid	Markson G (2009)	1
UBE2D2	0	UBC	7	x-ray crystallography, x-ray crystallography, enzymatic study, pull down, pull down	Juang YC (2012), Dou H (2012), Sheng Y (2012), Buetow L (2015), Zhang X (2017)	5
UBE2D2	0	MAP3K1	4	two hybrid	van Wijk SJ (2009)	1
IQCB1	3	MARCH7	0	affinity chromatography technology, affinity chromatography technology, pull down	Das A (2017), Das A (2017), Das A (2017)	3
PRKN	1	REL	5	two hybrid	Corominas R (2014)	1
MDM2	2	ITCH	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kubo N (2010), Kubo N (2010), Wu H (2015), Wu H (2015)	4
HNRNPA1	1	HNRNPL	3	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Close P (2012), Havugimana PC (2012), Roy R (2014), Hein MY (2015)	5
UBE2K	0	RNF4	1	two hybrid	Markson G (2009)	1
BAG3	4	UBA1	1	affinity chromatography technology	Chen Y (2013)	1
UBE2D2	0	UBOX5	4	two hybrid	Markson G (2009)	1
UBA1	1	UBE2K	0	pull down, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Seufert W (1990), Jin J (2007), Whitby FG (1998), Whitby FG (1998), Pickart CM (1994), Huguenin-Dezot N (2016)	6
UBE2D2	0	RNF5	0	two hybrid, pull down	Markson G (2009), Sakata E (2010)	2
UBE2V1	0	RNF5	0	two hybrid	Markson G (2009)	1
BARD1	4	PIAS4	5	two hybrid	Goehler H (2004)	1
UBE2K	0	UBOX5	4	two hybrid	Markson G (2009)	1
TRIM31	0	MKRN3	2	two hybrid	Woodsmith J (2012)	1
DSTYK	1	UBE2K	0	affinity chromatography technology	Ewing RM (2007)	1
UBE2I	0	TP53	0	two hybrid, two hybrid, two hybrid, enzymatic study, two hybrid, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Minty A (2000), Gallagher WM (1999), Shen Z (1996), Bernier-Villamor V (2002), Wang J (2008), Spektor TM (2011), Jakobs A (2007), Mohideen F (2009), Lin JY (2004), Bennett RL (2012), Heo KS (2013), Morimoto M (2003), Rodriguez MS (1999), Muller S (2000), Fernandez-Lloris R (2006), Mohan RD (2007), Brandt M (2013), Weger S (2005)	18
UBE2I	0	DZIP3	6	two hybrid	Markson G (2009)	1
HNRNPL	3	RNF144A	1	affinity chromatography technology	Fei T (2017)	1
UBE2I	0	TRIM27	2	two hybrid, affinity chromatography technology	Markson G (2009), Chu Y (2011)	2
HNRNPL	3	SENP1	0	affinity chromatography technology	Fei T (2017)	1
TP53	0	HNRNPA1	1	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
ITCH	1	HNRNPL	3	pull down, affinity chromatography technology	Ingham RJ (2005), Fei T (2017)	2
PRKN	1	HNRNPA1	1	affinity chromatography technology	Zanon A (2013)	1
TXN	1	TYMS	0	biochemical	Wan C (2015)	1
UBE2K	0	CASP12	1	enzymatic study	Song S (2008)	1
UBE2D2	0	BIRC8	0	two hybrid	Markson G (2009)	1
HNRNPL	3	NEDD4L	3	affinity chromatography technology	Fei T (2017)	1
LRSAM1	2	MKRN3	2	two hybrid	Woodsmith J (2012)	1
UBE2D2	0	PJA1	1	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Yu P (2002), Yu P (2002), Yu P (2002), Loch CM (2011)	4
RAB1A	0	UBE2K	0	biochemical	Wan C (2015)	1
MDM2	2	UBE2D2	0	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Iyappan S (2010), Dou H (2012), Brenkman AB (2008), Fang S (2000), Szypowska AA (2011), Okamoto K (2009), Busso CS (2009), Maguire M (2008), Sehat B (2008), Uldrijan S (2007), Yang Y (2005), Jin Y (2004), Roxburgh P (2012), Shloush J (2011), Rinaldo C (2007), Cheng Q (2009), Amson R (2011), Li X (2009), David Y (2011), Sosin AM (2012), Schumacher FR (2013), Bista M (2013), Mikawa T (2014), Lohrum MA (2001), Fang S (2001), Saville MK (2004), Rodriguez MS (1999), Auger KR (2005), Wu PY (2003), Wu H (2015), Yamauchi T (2014), Nomura K (2017), Kurokawa M (2013)	33
UBE2D2	0	SIAH1	2	two hybrid, two hybrid, pull down, pull down	van Wijk SJ (2009), Markson G (2009), Szargel R (2009), Winter M (2008)	4
BRCA1	7	BARD1	4	two hybrid, two hybrid, pull down, pull down, pull down, pull down, imaging technique, imaging technique, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, two hybrid, pull down, pull down, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, two hybrid, x-ray crystallography, imaging technique, imaging technique, two hybrid, affinity chromatography technology, protein complementation assay, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology	Wu LC (1996), Wang Q (2001), Wang Q (2001), Mallery DL (2002), Wu-Baer F (2003), Hashizume R (2001), Fabbro M (2002), Rodriguez JA (2004), Brzovic PS (2003), Nishikawa H (2004), Dong Y (2003), Dong Y (2003), Chiba N (2001), Kleiman FE (2001), Kleiman FE (2001), Kleiman FE (2001), Wu LC (1996), Morris JR (2002), Brzovic PS (2001), Xia Y (2003), Meza JE (1999), Kentsis A (2002), Hashizume R (2001), Fabbro M (2004), Brzovic PS (2001), Yu X (1998), Jin Y (1997), Scully R (1999), Fabbro M (2004), Kleiman FE (1999), Kleiman FE (1999), Tascou S (2003), Brzovic PS (2003), Benezra M (2003), Meza JE (1999), Cantor SB (2001), Wang Q (1998), Ryser S (2009), Ryser S (2009), Nishikawa H (2009), Nishikawa H (2009), Sobhian B (2007), Harte MT (2010), Simons AM (2006), Wei L (2008), Kumaraswamy E (2007), Kumaraswamy E (2007), Dizin E (2010), Dizin E (2010), Greenberg RA (2006), Greenberg RA (2006), Greenberg RA (2006), Zhu Q (2011), Chen A (2002), Chen A (2002), Sy SM (2009), Sy SM (2009), Nelson AC (2010), Nelson AC (2010), Morris JR (2006), Brzovic PS (2001), Mok MT (2010), Au WW (2005), Ayi TC (1998), Choudhury AD (2005), Sarkar M (2008), Sarkar M (2008), Thakar A (2010), Lu Y (2012), Kentsis A (2002), Christou CM (2014), Christou CM (2014), Sevcik J (2013), Johnson N (2013), Matsuzawa A (2014), Matsuzawa A (2014), Hill SJ (2014), Hill SJ (2014), Hill SJ (2014), Starita LM (2015), Hu Y (2014), Wu W (2015), Loke J (2015), Densham RM (2016), Boukerroucha M (2015), Huttlin EL (2017), Liang Y (2017), Liang Y (2017), Liang Y (2017), Ertych N (2016), Ertych N (2016)	91
BAG3	4	WDR1	3	affinity chromatography technology, affinity chromatography technology	Chen Y (2013), Chen Y (2013)	2
UBC	7	TRIM27	2	affinity chromatography technology	Matsumoto M (2005)	1
UBE2N	1	AMFR	2	two hybrid, two hybrid	van Wijk SJ (2009), Markson G (2009)	2
UBE2K	0	RNF114	0	two hybrid	Markson G (2009)	1
UHRF2	1	CCNB1	3	far western blotting, affinity chromatography technology, affinity chromatography technology	Mori T (2011), Mori T (2011), Mori T (2011)	3
UBE2N	1	BIRC8	0	two hybrid	Markson G (2009)	1
UBE2D2	0	TRIM5	4	two hybrid, pull down, pull down	Markson G (2009), Yamauchi K (2008), Xu L (2003)	3
UBE2V1	0	TRIM39	0	two hybrid	Markson G (2009)	1
PRKN	1	UBE2D2	0	pull down, pull down, pull down, pull down, pull down, pull down	Joch M (2007), Imai Y (2002), Chaugule VK (2011), Durcan TM (2011), Caulfield TR (2014), Kazlauskaite A (2014)	6
BRCA1	7	MAP3K1	4	two hybrid	Woods NT (2012)	1
RNF4	1	UBC	7	enzymatic study, enzymatic study	Groocock LM (2014), Branigan E (2015)	2