PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
AP2B1	3	AP2M1	5	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Rual JF (2005), Brehme M (2009), Li J (2013), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	6
IRS2	6	DVL2	5	affinity chromatography technology, affinity chromatography technology	Geng Y (2014), Geng Y (2014)	2
NTRK1	1	EPN1	4	affinity chromatography technology	Emdal KB (2015)	1
ITGA4	4	EPS15	1	affinity chromatography technology	Byron A (2012)	1
XPO1	8	PHGDH	4	affinity chromatography technology	Kirli K (2015)	1
PTPN12	2	EPN1	4	biochemical	Kristensen AR (2012)	1
EPS15	1	EPN3	2	affinity chromatography technology	Ko G (2010)	1
GTSE1	3	AP2M1	5	affinity chromatography technology	Hein MY (2015)	1
NTRK1	1	UBC	7	affinity chromatography technology	Emdal KB (2015)	1
RNF11	0	AP2M1	5	affinity chromatography technology	Poulsen SL (2013)	1
RNF11	0	EPS15	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Li H (2004), Kostaras E (2012), Kostaras E (2014)	3
EGFR	5	AP2M1	5	protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Deribe YL (2009), Foerster S (2013), Li J (2013), Tong J (2014), Li J (2013)	5
NTRK1	1	IRS2	6	affinity chromatography technology	Emdal KB (2015)	1
MOV10	6	AP2A2	3	affinity chromatography technology	Castello A (2012)	1
UBQLN2	0	UBC	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chang L (2015), Hjerpe R (2016), Hjerpe R (2016)	3
EPN1	4	ERBB3	3	affinity chromatography technology	Szymanska M (2016)	1
SLC6A3	6	EPS15	1	affinity chromatography technology	Sorkina T (2006)	1
SMAD5	2	PTPN12	2	two hybrid	Colland F (2004)	1
SMURF1	4	XPO1	8	affinity chromatography technology	Tajima Y (2003)	1
EPN1	4	PLEKHB2	4	two hybrid	Rolland T (2014)	1
SMURF1	4	EPN1	4	enzymatic study	Andrews PS (2010)	1
FBXO25	1	PHGDH	4	affinity chromatography technology	Teixeira FR (2010)	1
EPN1	4	CRMP1	0	two hybrid	Stelzl U (2005)	1
MAP3K1	4	NOTCH1	25	enzymatic study, affinity chromatography technology	Ahn JS (2016), Ahn JS (2016)	2
ITGA4	4	CLTC	12	affinity chromatography technology	Byron A (2012)	1
NTRK1	1	CDK1	0	affinity chromatography technology	Emdal KB (2015)	1
RNF11	0	AP2B1	3	affinity chromatography technology	Poulsen SL (2013)	1
RNF11	0	EPN1	4	two hybrid	Colland F (2004)	1
FBXO25	1	EGFR	5	enzymatic study	Teixeira FR (2013)	1
NTRK1	1	PTPN12	2	affinity chromatography technology	Emdal KB (2015)	1
NOTCH1	25	EPN1	4	affinity chromatography technology	Sorensen EB (2010)	1
AP2M1	5	EPS15L1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li J (2013), Huttlin EL (2015), Huttlin EL (2017)	3
NTRK1	1	UBQLN2	0	affinity chromatography technology	Emdal KB (2015)	1
EPN1	4	BCAR1	6	biochemical	Kristensen AR (2012)	1
BCAR1	6	PTPN12	2	affinity chromatography technology, pull down, pull down, enzymatic study, pull down, affinity chromatography technology, pull down, affinity chromatography technology, bioid	Lin Y (2003), Garton AJ (1997), Garton AJ (1997), Garton AJ (1997), Cote JF (1998), Cote JF (1998), Garton AJ (1996), Garton AJ (1996), St-Denis N (2016)	9
EHD2	3	EPN1	4	affinity chromatography technology	Ko G (2010)	1
SMURF1	4	UBC	7	affinity chromatography technology, enzymatic study, pull down	Xie Y (2013), Kristariyanto YA (2015), Zhang Y (2017)	3
NTRK1	1	AP2A2	3	affinity chromatography technology	Emdal KB (2015)	1
GTSE1	3	PHGDH	4	affinity chromatography technology	Hein MY (2015)	1
NTRK1	1	CLTC	12	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	EHD1	5	affinity chromatography technology	Tong J (2014)	1
EPN1	4	CLTC	12	affinity chromatography technology, affinity chromatography technology	Drake MT (2000), Hein MY (2015)	2
FZD8	2	LRP6	3	affinity chromatography technology, pull down	Semenov M (2005), Semenov MV (2001)	2
SCNN1A	1	SCNN1G	2	affinity chromatography technology	Buck TM (2017)	1
AP2M1	5	UBC	7	affinity chromatography technology, pull down	Brehme M (2009), Zhang X (2017)	2
AP1M2	2	AP1B1	6	affinity chromatography technology, biochemical, affinity chromatography technology	Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	3
EPN1	4	AP2A2	3	affinity chromatography technology, pull down	Chen H (1998), Chen H (1998)	2
EGFR	5	AP2A1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Foerster S (2013), Tong J (2014), Li J (2013)	4
CLTC	12	AP2A2	3	pull down, two hybrid, affinity chromatography technology	McMahon HT (1997), Knuehl C (2006), Hein MY (2015)	3
AP2M1	5	EHD2	3	pull down	Park SY (2004)	1
ERBB3	3	AP1M2	2	affinity chromatography technology	Li J (2013)	1
FN1	17	AP2A1	1	affinity chromatography technology	Humphries JD (2009)	1
UBC	7	EPN1	4	pull down, pull down, pull down, pull down	Fenner BJ (2009), Nathan JA (2013), Hawryluk MJ (2006), Zhang X (2017)	4
ITGA4	4	AP2A1	1	affinity chromatography technology	Byron A (2012)	1
GTSE1	3	AP1B1	6	affinity chromatography technology	Hein MY (2015)	1
KDR	4	PTPN12	2	two hybrid	Yao Z (2017)	1
EHD1	5	EPN3	2	affinity chromatography technology	Ko G (2010)	1
SCNN1G	2	EPN1	4	affinity chromatography technology, pull down	Wang H (2006), Wang H (2006)	2
EPS15	1	REPS2	1	affinity chromatography technology, far western blotting	Nakashima S (1999), Nakashima S (1999)	2
NXF1	0	CLTC	12	affinity chromatography technology	Castello A (2012)	1
SLC25A41	0	EPS15	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGFR	5	EPN1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sigismund S (2005), Bertelsen V (2011), Kazazic M (2009)	3
NOTCH1	25	DAZAP2	1	two hybrid	Daakour S (2016)	1
PLPPR2	1	EPN1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
AP2B1	3	EPN1	4	biochemical	Kristensen AR (2012)	1
FLVCR2	0	EPN1	4	affinity chromatography technology	Huttlin EL (2017)	1
AP2M1	5	AP2A1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Brehme M (2009), Li J (2013), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	5
XPO1	8	EPN1	4	affinity chromatography technology	Kirli K (2015)	1
EGFR	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique	Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014)	6
ITGA4	4	AP2B1	3	affinity chromatography technology	Byron A (2012)	1
EGFR	5	AP1M2	2	affinity chromatography technology	Foerster S (2013)	1
GTSE1	3	RALBP1	2	affinity chromatography technology	Hein MY (2015)	1
VCAM1	2	UBC	7	affinity chromatography technology	Humphries JD (2009)	1
RALBP1	2	EPN1	4	affinity chromatography technology, affinity chromatography technology	Rosse C (2003), Coon BG (2010)	2
EGFR	5	AP2A2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Tong J (2014), Li J (2013)	3
RNF11	0	UBQLN2	0	two hybrid	Colland F (2004)	1
FBXO25	1	EPN1	4	enzymatic study	Teixeira FR (2013)	1
NTRK1	1	XPO1	8	affinity chromatography technology	Emdal KB (2015)	1
MAP3K1	4	DVL2	5	affinity chromatography technology	Zhang Y (2000)	1
SCNN1B	1	EPN1	4	affinity chromatography technology, pull down	Wang H (2006), Wang H (2006)	2
NTRK1	1	AP1B1	6	affinity chromatography technology	Emdal KB (2015)	1
GTSE1	3	CLTC	12	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
NXF1	0	FLVCR2	0	affinity chromatography technology	Castello A (2012)	1
XPO1	8	AP2A1	1	affinity chromatography technology	Kirli K (2015)	1
EPS15	1	AP2B1	3	affinity chromatography technology	Brehme M (2009)	1
EPS15	1	AP2M1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009), Li J (2013), Huttlin EL (2015), Huttlin EL (2017)	5
SMURF1	4	CLTC	12	affinity chromatography technology	Xie Y (2013)	1
AP2B1	3	AP1M2	2	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Rual JF (2005), Rual JF (2005), Rolland T (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	6
EPN1	4	EPN3	2	imaging technique, affinity chromatography technology, affinity chromatography technology	Ko G (2010), Huttlin EL (2015), Huttlin EL (2017)	3
GTSE1	3	AP2A2	3	affinity chromatography technology	Hein MY (2015)	1
ITGA4	4	AP2M1	5	affinity chromatography technology	Byron A (2012)	1
AP2A1	1	AP2A2	3	biochemical	Havugimana PC (2012)	1
NTRK1	1	EPS15	1	affinity chromatography technology	Emdal KB (2015)	1
AP2M1	5	DVL2	5	two hybrid	Rual JF (2005)	1
ITGA4	4	XPO1	8	affinity chromatography technology	Byron A (2012)	1
EHD1	5	AP2A1	1	pull down	Rotem-Yehudar R (2001)	1
NXF1	0	XPO1	8	affinity chromatography technology	Bachi A (2000)	1
VCAM1	2	CLTC	12	affinity chromatography technology	Humphries JD (2009)	1
UBC	7	AP2A2	3	pull down	Zhang X (2017)	1
FN1	17	PHGDH	4	affinity chromatography technology	Humphries JD (2009)	1
GAS2L1	2	EPN1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SCNN1A	1	EPN1	4	affinity chromatography technology, pull down	Wang H (2006), Wang H (2006)	2
EGFR	5	AP2B1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Tong J (2014), Li J (2013)	3
OCLN	1	EPS15	1	affinity chromatography technology	Murakami T (2009)	1
GTSE1	3	AP2A1	1	affinity chromatography technology	Hein MY (2015)	1
MOV10	6	EPN1	4	affinity chromatography technology	Castello A (2012)	1
SLC25A41	0	EPN1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DAZAP2	1	MED31	0	two hybrid	Vinayagam A (2011)	1
IRS2	6	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Argetsinger LS (1996), Verdier F (1997), Kim B (1998), Hamer I (2002), Calegari VC (2005), Tzatsos A (2009), Ren W (2013), Hein MY (2015)	8
TMEM17	0	OCLN	1	bioid	Gupta GD (2015)	1
EPN3	2	SMURF1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
AP2M1	5	AP2A2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Brehme M (2009), Li J (2013), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	5
RALBP1	2	REPS2	1	affinity chromatography technology, pull down, affinity chromatography technology	Ikeda M (1998), Ikeda M (1998), Huttlin EL (2017)	3
TMEM17	0	EPN1	4	bioid	Gupta GD (2015)	1
IRS2	6	EPN1	4	affinity chromatography technology, affinity chromatography technology	Fukushima T (2015), Fukushima T (2015)	2
AP1B1	6	AP2M1	5	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Page LJ (1995), Brehme M (2009), Li J (2013), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	6
RALBP1	2	GTF3A	5	affinity chromatography technology	Rosse C (2003)	1
RNF11	0	SMURF1	4	two hybrid	Colland F (2004)	1
SCNN1B	1	SCNN1G	2	protein complementation assay	Faria D (2012)	1
TMEM17	0	AP1B1	6	bioid	Gupta GD (2015)	1
MAP3K1	4	PLEKHB2	4	enzymatic study	Charlaftis N (2014)	1
EPS15	1	TFAP2A	1	pull down, pull down	Benmerah A (1998), Chi S (2008)	2
NTRK1	1	EPS15L1	1	affinity chromatography technology	Emdal KB (2015)	1
GTSE1	3	AP2B1	3	affinity chromatography technology	Hein MY (2015)	1
NTRK1	1	AP2A1	1	affinity chromatography technology	Emdal KB (2015)	1
EPN1	4	AP1B1	6	affinity chromatography technology	Mills IG (2003)	1
NXF1	0	EPS15L1	1	affinity chromatography technology	Castello A (2012)	1
UBC	7	AP2A1	1	pull down	Zhang X (2017)	1
DLL1	3	EPN1	4	affinity chromatography technology, affinity chromatography technology	Meloty-Kapella L (2012), Meloty-Kapella L (2012)	2
FN1	17	ITGA4	4	affinity chromatography technology	Humphries JD (2009)	1
AP1M2	2	EHD2	3	pull down	Park SY (2004)	1
EGFR	5	FN1	17	protein complementation assay	Deribe YL (2009)	1
AP2A1	1	AP2B1	3	biochemical	Wan C (2015)	1
FN1	17	CDK1	0	affinity chromatography technology	Humphries JD (2009)	1
MAP3K1	4	EPN1	4	enzymatic study	Charlaftis N (2014)	1
VCAM1	2	AP2B1	3	affinity chromatography technology	Humphries JD (2009)	1
EPN1	4	EPS15L1	1	affinity chromatography technology	Chen H (1998)	1
VCAM1	2	EPS15	1	affinity chromatography technology	Humphries JD (2009)	1
CLTC	12	AP2B1	3	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Slepnev VI (2000), Knuehl C (2006), Knuehl C (2006), Hein MY (2015)	4
EPN1	4	MED31	0	two hybrid	Stelzl U (2005)	1
NTRK1	1	PIK3R1	6	affinity chromatography technology	Emdal KB (2015)	1
UBQLN2	0	EPN1	4	affinity chromatography technology	NDiaye EN (2008)	1
PHGDH	4	EPN1	4	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CDK1	0	REPS2	1	enzymatic study	Kariya K (2000)	1
EPN1	4	CEP126	0	two hybrid	Stelzl U (2005)	1
SMAD5	2	SMURF1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, two hybrid, two hybrid, enzymatic study	Lu K (2008), Komuro A (2004), Ebisawa T (2001), Nie J (2010), Alarcon C (2009), Murakami G (2003), Sangadala S (2007), Sangadala S (2007), Sangadala S (2007), Haag J (2006), Colland F (2004), Lu K (2008)	12
XPO1	8	GTSE1	3	affinity chromatography technology	Kirli K (2015)	1
NTRK1	1	CRMP1	0	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	MAP3K1	4	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	DVL2	5	affinity chromatography technology	Emdal KB (2015)	1
ITGA4	4	CDK1	0	affinity chromatography technology	Byron A (2012)	1
AP2M1	5	REPS2	1	affinity chromatography technology	Huttlin EL (2017)	1
UBC	7	AP2B1	3	pull down	Zhang X (2017)	1
NTRK1	1	EGFR	5	affinity chromatography technology	Emdal KB (2015)	1
CLTC	12	EPS15	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Chi S (2008)	2
SLC2A14	2	EPN1	4	affinity chromatography technology	Huttlin EL (2017)	1
EGFR	5	PHGDH	4	affinity chromatography technology	Foerster S (2013)	1
FBXO25	1	UBQLN2	0	enzymatic study	Teixeira FR (2013)	1
LAPTM5	3	EPN1	4	two hybrid	Colland F (2004)	1
NXF1	0	EPN1	4	affinity chromatography technology	Castello A (2012)	1
XPO1	8	SMAD5	2	affinity chromatography technology	Kirli K (2015)	1
CLTC	12	AP1B1	6	pull down	McMahon HT (1997)	1
AP1M2	2	SCNN1B	1	affinity chromatography technology	Wang H (2006)	1
GTSE1	3	EPN1	4	affinity chromatography technology	Hein MY (2015)	1
FN1	17	AP2A2	3	affinity chromatography technology	Humphries JD (2009)	1
AP1M2	2	SCNN1A	1	affinity chromatography technology	Wang H (2006)	1
VCAM1	2	AP2M1	5	affinity chromatography technology	Humphries JD (2009)	1
EPS15	1	AP1B1	6	affinity chromatography technology, affinity chromatography technology	Mills IG (2003), Brehme M (2009)	2
EGFR	5	CDK1	0	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Tong J (2008), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014)	4
SLC25A41	0	AP2M1	5	affinity chromatography technology	Huttlin EL (2015)	1
NXF1	0	UBC	7	affinity chromatography technology	Castello A (2012)	1
XPO1	8	EPS15L1	1	affinity chromatography technology	Kirli K (2015)	1
EPN1	4	KDR	4	affinity chromatography technology, affinity chromatography technology	Pasula S (2012), Pasula S (2012)	2
ITGA4	4	EPN1	4	affinity chromatography technology	Byron A (2012)	1
AP2A2	3	AP1B1	6	biochemical	Wan C (2015)	1
EPS15	1	UBC	7	pull down, pull down, affinity chromatography technology, pull down, pull down, pull down	Woelk T (2006), De Schutter J (2009), Brehme M (2009), Hoeller D (2006), Zhang X (2017), Kristariyanto YA (2017)	6
ERBB3	3	PTPN12	2	two hybrid	Yao Z (2017)	1
EHD1	5	CLTC	12	pull down, biochemical	Rotem-Yehudar R (2001), Wan C (2015)	2
FN1	17	UBC	7	affinity chromatography technology	Humphries JD (2009)	1
EHD1	5	EPN1	4	affinity chromatography technology	Ko G (2010)	1
XPO1	8	AP1B1	6	affinity chromatography technology	Kirli K (2015)	1
AP2A1	1	EPN1	4	affinity chromatography technology, affinity chromatography technology	Kariya K (2000), Kariya K (2000)	2
EGFR	5	XPO1	8	affinity chromatography technology	Foerster S (2013)	1
RALBP1	2	EPN3	2	affinity chromatography technology	Coon BG (2010)	1
NTRK1	1	PHGDH	4	affinity chromatography technology	Emdal KB (2015)	1
UBC	7	DAZAP2	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
EPN1	4	FLT4	5	affinity chromatography technology	Liu X (2014)	1
MOV10	6	UBC	7	affinity chromatography technology	Castello A (2012)	1
NOTCH1	25	DLL1	3	pull down	Shimizu K (2000)	1
VCAM1	2	ITGA4	4	affinity chromatography technology, affinity chromatography technology	Humphries JD (2009), Byron A (2012)	2
FN1	17	AP2B1	3	affinity chromatography technology	Humphries JD (2009)	1
TFAP2A	1	AP1M2	2	affinity chromatography technology	Keyel PA (2008)	1
FBXO25	1	XPO1	8	affinity chromatography technology	Teixeira FR (2010)	1
EGFR	5	AP1B1	6	affinity chromatography technology, affinity chromatography technology	Tong J (2014), Li J (2013)	2
UBC	7	PHGDH	4	affinity chromatography technology	Matsumoto M (2005)	1
FN1	17	CLTC	12	affinity chromatography technology	Humphries JD (2009)	1
NXF1	0	AP2A2	3	affinity chromatography technology	Castello A (2012)	1
EPN1	4	LRP6	3	affinity chromatography technology	Chang B (2015)	1
XPO1	8	DVL2	5	affinity chromatography technology	Kirli K (2015)	1
ERBB3	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hellyer NJ (2001), Lin J (1999), Crovello CS (1998), Graus-Porta D (1997), Jones RB (2006), Li J (2013), Servidei T (2008), Servidei T (2008), Ritch PS (2005), Tang X (2002)	10
DAZAP2	1	EPN1	4	two hybrid	Rolland T (2014)	1
SLC6A3	6	EPN1	4	affinity chromatography technology	Sorkina T (2006)	1
XPO1	8	AP2B1	3	affinity chromatography technology	Kirli K (2015)	1
EPN1	4	GTF3A	5	affinity chromatography technology	Rosse C (2003)	1
AP2M1	5	CLTC	12	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Hein MY (2015)	2
EPN1	4	REPS2	1	affinity chromatography technology, far western blotting, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology	Morinaka K (1999), Morinaka K (1999), Morinaka K (1999), Sugiyama S (2005), Kariya K (2000), Kariya K (2000)	6
EPN1	4	SMAD5	2	biochemical	Havugimana PC (2012)	1
TMEM17	0	LRP6	3	bioid	Gupta GD (2015)	1
SLC25A41	0	AP2A1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UBQLN2	0	EPS15	1	affinity chromatography technology	NDiaye EN (2008)	1
AP2A1	1	AP1B1	6	biochemical	Wan C (2015)	1
TMEM17	0	NOTCH1	25	bioid	Gupta GD (2015)	1
AP2A1	1	RALBP1	2	affinity chromatography technology, affinity chromatography technology	Kariya K (2000), Huttlin EL (2017)	2
EHD2	3	CLTC	12	biochemical	Wan C (2015)	1
VCAM1	2	EPN1	4	affinity chromatography technology	Humphries JD (2009)	1
DAZAP2	1	PLEKHB2	4	two hybrid	Rolland T (2014)	1
EGFR	5	UBC	7	affinity chromatography technology, affinity chromatography technology	Tong J (2009), Bishop N (2002)	2
AP2A1	1	REPS2	1	affinity chromatography technology, affinity chromatography technology	Kariya K (2000), Kariya K (2000)	2
EPN1	4	FZD7	1	affinity chromatography technology	Chang B (2015)	1
AP1M2	2	SCNN1G	2	affinity chromatography technology	Wiemuth D (2007)	1
XPO1	8	ARRDC1	4	affinity chromatography technology	Kirli K (2015)	1
FN1	17	EPS15	1	affinity chromatography technology	Humphries JD (2009)	1
BCAR1	6	PIK3R1	6	affinity chromatography technology, pull down	Li E (2000), Li E (2000)	2
EPS15	1	AP2A2	3	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Bean AJ (2000), Roxrud I (2008), Brehme M (2009), Shimada A (2016)	4
XPO1	8	MAP3K1	4	affinity chromatography technology	Kirli K (2015)	1
SLC25A41	0	RALBP1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
XPO1	8	IRS2	6	affinity chromatography technology	Kirli K (2015)	1
TFAP2A	1	EPN1	4	affinity chromatography technology, pull down	Sugiyama S (2005), Hawryluk MJ (2006)	2
TMEM17	0	EPS15	1	bioid	Gupta GD (2015)	1
EPS15	1	AP2A1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	van Delft S (1997), Kariya K (2000), Confalonieri S (2000), Brehme M (2009)	4
VCAM1	2	XPO1	8	affinity chromatography technology	Humphries JD (2009)	1
MOV10	6	EPS15L1	1	affinity chromatography technology	Castello A (2012)	1
GTSE1	3	EPS15	1	affinity chromatography technology	Hein MY (2015)	1
TFAP2A	1	AP2B1	3	affinity chromatography technology	Keyel PA (2008)	1
XPO1	8	AP2M1	5	affinity chromatography technology	Kirli K (2015)	1
EPN1	4	AP1M2	2	affinity chromatography technology	Wang H (2006)	1
AP2M1	5	RALBP1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
LDLRAD4	1	EPN1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FN1	17	XPO1	8	affinity chromatography technology	Humphries JD (2009)	1
MOV10	6	MED31	0	affinity chromatography technology	Castello A (2012)	1
FN1	17	EPN1	4	affinity chromatography technology	Humphries JD (2009)	1
SCNN1B	1	SCNN1A	1	protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Faria D (2012), Faria D (2012), Faria D (2012), Buck TM (2017)	4
EGFR	5	IRS2	6	affinity chromatography technology	Tong J (2008)	1
TMEM17	0	PIK3R1	6	bioid	Gupta GD (2015)	1
ARRDC1	4	EPN1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FBXO25	1	KDR	4	enzymatic study	Teixeira FR (2013)	1
EPN1	4	DVL2	5	affinity chromatography technology, affinity chromatography technology	Chang B (2015), Chang B (2015)	2
AP2M1	5	EPN1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PIK3R1	6	EPN1	4	affinity chromatography technology	Bulut GB (2013)	1
LAPTM5	3	EPN3	2	two hybrid	Colland F (2004)	1
LDLRAD4	1	SMURF1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
VCAM1	2	CDK1	0	affinity chromatography technology	Humphries JD (2009)	1
RNF11	0	EPN3	2	two hybrid	Colland F (2004)	1
SMURF1	4	UBQLN2	0	enzymatic study	Andrews PS (2010)	1
RNF11	0	UBC	7	two hybrid, two hybrid	Li H (2004), Colland F (2004)	2
NTRK1	1	EHD1	5	affinity chromatography technology	Emdal KB (2015)	1
VCAM1	2	AP2A1	1	affinity chromatography technology	Humphries JD (2009)	1
NTRK1	1	AP2B1	3	affinity chromatography technology	Emdal KB (2015)	1
FN1	17	AP2M1	5	affinity chromatography technology	Humphries JD (2009)	1
UBC	7	LAPTM5	3	pull down	Pak Y (2006)	1
ITGA4	4	UBC	7	affinity chromatography technology	Byron A (2012)	1
EGFR	5	PTPN12	2	protein complementation assay, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Deribe YL (2009), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Yao Z (2017)	5
EGFR	5	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marques MM (1999), Li J (2013), Li J (2013), Sharif A (2009)	4
LAPTM5	3	EPS15	1	two hybrid	Colland F (2004)	1
AP2A2	3	AP2B1	3	biochemical	Wan C (2015)	1
EPN1	4	EPS15	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology	Chen H (1998), Chen H (1998), Hoeller D (2006), Ko G (2010), Sugiyama S (2005), Huang JH (2008)	6
TADA2B	3	EPN1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
OCLN	1	EPN1	4	affinity chromatography technology	Murakami T (2009)	1
RNF11	0	AP2A1	1	affinity chromatography technology	Poulsen SL (2013)	1
XPO1	8	EPS15	1	affinity chromatography technology	Kirli K (2015)	1
EHD2	3	EPN3	2	affinity chromatography technology	Ko G (2010)	1
CLTC	12	AP2A1	1	affinity chromatography technology	Hein MY (2015)	1
UBC	7	EPS15L1	1	pull down	Zhang X (2017)	1
EPN3	2	PHGDH	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDK1	0	EPN1	4	enzymatic study	Kariya K (2000)	1
EPS15	1	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	van Delft S (1997), Sigismund S (2005), Bertelsen V (2011), Parachoniak CA (2009), Parachoniak CA (2009), Hoeller D (2006)	6
EPN1	4	FZD8	2	affinity chromatography technology	Chang B (2015)	1
NTRK1	1	MOV10	6	affinity chromatography technology	Emdal KB (2015)	1