Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
N6AMT1 rs2254638 G clopidogrel metabolism/PK yes This variant was associated with decreased active metabolite H4 concentration. Allele G is associated with decreased metabolism of clopidogrel as compared to genotype AA. 27981573 1448624859
N6AMT1 rs2254638 G clopidogrel efficacy yes This variant is associated with decreased H4 concentration, and decreased antiplatelet effects of clopidogrel with a higher PRU. Allele G is associated with decreased response to clopidogrel in people with Coronary Artery Disease as compared to allele A. 30487649 1450117776