Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
GRIK3 2899 Selurampanel CHEMBL3545042 antagonist ChemblInteractions
GRIK3 2899 L-GLUTAMATE CHEMBL575060 DrugBank 1371217, 17139284, 17016423, 8622118, 11058796
GRIK3 2899 TOPIRAMATE CHEMBL220492 antagonist ChemblInteractions
GRIK3 2899 TEZAMPANEL CHEMBL14935 antagonist TdgClinicalTrial, ChemblInteractions

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
GRIK3 rs6691840 C botulinum toxin type a efficacy no No significant difference in allele frequency between responders and non-responders. Allele C is not associated with response to botulinum toxin type a in women with Migraine NOS as compared to allele A. 31014225 1451104844