Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
INVS rs10123866 G duloxetine efficacy yes Variant was suggestively significant, but did not reach genome-wide significance. Response was defined by >50% decrease in Montgomery-Asberg Depression Rating Scale (MADRS) score at the end of treatment. Allele G is associated with increased response to duloxetine in people with Depressive Disorder, Major as compared to allele A. 29407288 1449167881