Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
SIN3A rs7166737 GG hydroxyurea efficacy yes Significance was measured between expected numbers of GG hydroxyurea responders and non-responders, and between numbers of AA hydroxyurea responders and non-responders Genotype GG is associated with decreased response to hydroxyurea in people with Thalassemia as compared to genotypes AA + AG. 27767389 1448422658