Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
GABRA4 2557 TEMAZEPAM CHEMBL967 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 18384456, 20138190
GABRA4 2557 PRIMIDONE CHEMBL856 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 10209232
GABRA4 2557 OXAZEPAM CHEMBL568 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 18384456, 11752090
GABRA4 2557 MEPHOBARBITAL CHEMBL45029 potentiator DrugBank 10209232, 21194017
GABRA4 2557 MUSCIMOL CHEMBL273481 agonist GuideToPharmacologyInteractions
GABRA4 2557 CHEMBL34155 CHEMBL34155 agonist GuideToPharmacologyInteractions
GABRA4 2557 BRETAZENIL CHEMBL366947 allosteric modulator GuideToPharmacologyInteractions
GABRA4 2557 Ro-154513 CHEMBL6597 allosteric modulator GuideToPharmacologyInteractions
GABRA4 2557 BICUCULLINE CHEMBL417990 antagonist GuideToPharmacologyInteractions
GABRA4 2557 GABAZINE CHEMBL32503 antagonist GuideToPharmacologyInteractions
GABRA4 2557 T-BUTYLBICYCLOPHOSPHOROTHIONATE CHEMBL485673 channel blocker GuideToPharmacologyInteractions
GABRA4 2557 FLUNITRAZEPAM CHEMBL13280 agonist TEND, TdgClinicalTrial, DrugBank 20638393, 17976880, 17139284, 17016423, 20858465
GABRA4 2557 BROMAZEPAM CHEMBL277062 potentiator TdgClinicalTrial, TEND, DrugBank 18384456
GABRA4 2557 NITRAZEPAM CHEMBL13209 potentiator TdgClinicalTrial, TEND, DrugBank 18384456, 11752090
GABRA4 2557 CHLORDIAZEPOXIDE HYDROCHLORIDE CHEMBL1200703 positive allosteric modulator ChemblInteractions
GABRA4 2557 GLUTETHIMIDE CHEMBL1102 ChemblInteractions
GABRA4 2557 METHYPRYLON CHEMBL1200790 positive allosteric modulator ChemblInteractions
GABRA4 2557 PRAZEPAM CHEMBL969 positive allosteric modulator ChemblInteractions
GABRA4 2557 PENTOBARBITAL SODIUM CHEMBL971 positive allosteric modulator ChemblInteractions
GABRA4 2557 ETOMIDATE CHEMBL681 ChemblInteractions
GABRA4 2557 FLURAZEPAM CHEMBL968 TdgClinicalTrial, TEND
GABRA4 2557 TOPIRAMATE CHEMBL220492 ChemblInteractions
GABRA4 2557 ISOFLURANE CHEMBL1256 positive allosteric modulator ChemblInteractions
GABRA4 2557 PHENOBARBITAL CHEMBL40 TdgClinicalTrial, TEND
GABRA4 2557 DIAZEPAM CHEMBL12 positive allosteric modulator ChemblInteractions
GABRA4 2557 ESTAZOLAM CHEMBL285674 positive allosteric modulator ChemblInteractions
GABRA4 2557 ISOGUVACINE CHEMBL39071 agonist GuideToPharmacologyInteractions
GABRA4 2557 CHEMBL274866 CHEMBL274866 allosteric modulator GuideToPharmacologyInteractions
GABRA4 2557 ZINC ION CHEMBL1236970 allosteric modulator GuideToPharmacologyInteractions
GABRA4 2557 PICROTOXIN CHEMBL1908342 channel blocker GuideToPharmacologyInteractions
GABRA4 2557 HEXOBARBITAL CHEMBL7728 potentiator TdgClinicalTrial, TEND, DrugBank 10209232
GABRA4 2557 LORAZEPAM CHEMBL580 positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND
GABRA4 2557 ESZOPICLONE CHEMBL1522 positive allosteric modulator ChemblInteractions
GABRA4 2557 CLONAZEPAM CHEMBL452 positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND
GABRA4 2557 BUTABARBITAL SODIUM CHEMBL1200982 positive allosteric modulator ChemblInteractions
GABRA4 2557 ACAMPROSATE CALCIUM CHEMBL2068724 ChemblInteractions
GABRA4 2557 METHOHEXITAL SODIUM CHEMBL30219 positive allosteric modulator ChemblInteractions
GABRA4 2557 QUAZEPAM CHEMBL1200472 positive allosteric modulator ChemblInteractions
GABRA4 2557 FLURAZEPAM HYDROCHLORIDE CHEMBL1200602 positive allosteric modulator ChemblInteractions
GABRA4 2557 HALOTHANE CHEMBL931 positive allosteric modulator ChemblInteractions
GABRA4 2557 ADIPIPLON CHEMBL2103791 partial agonist TdgClinicalTrial, ChemblInteractions
GABRA4 2557 SECOBARBITAL SODIUM CHEMBL1200903 positive allosteric modulator ChemblInteractions
GABRA4 2557 TRICLOFOS SODIUM CHEMBL1200789 ChemblInteractions
GABRA4 2557 PF-06372865 CHEMBL3707402 agonist ChemblInteractions
GABRA4 2557 RESEQUINIL CHEMBL2107801 inverse agonist ChemblInteractions
GABRA4 2557 Lorediplon CHEMBL3707317 positive allosteric modulator ChemblInteractions
GABRA4 2557 TALBUTAL CHEMBL1200802 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 10209232
GABRA4 2557 MEPROBAMATE CHEMBL979 agonist TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 19244096, 9067327
GABRA4 2557 SECOBARBITAL CHEMBL447 potentiator TdgClinicalTrial, TEND, DrugBank 10209232
GABRA4 2557 THIOPENTAL CHEMBL441 potentiator TdgClinicalTrial, TEND, DrugBank 10209232
GABRA4 2557 TRIAZOLAM CHEMBL646 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 18384456, 11752090
GABRA4 2557 ISONIPECOTIC ACID CHEMBL279998 agonist GuideToPharmacologyInteractions
GABRA4 2557 CHEMBL70176 CHEMBL70176 allosteric modulator GuideToPharmacologyInteractions
GABRA4 2557 FLUMAZENIL CHEMBL407 allosteric modulator GuideToPharmacologyInteractions, ChemblInteractions
GABRA4 2557 METHOCTRAMINE CHEMBL27673 allosteric modulator GuideToPharmacologyInteractions
GABRA4 2557 APROBARBITAL CHEMBL7863 potentiator DrugBank 10209232
GABRA4 2557 BUTETHAL CHEMBL404422 potentiator TdgClinicalTrial, TEND, DrugBank 10209232
GABRA4 2557 GANAXOLONE CHEMBL1568698 TdgClinicalTrial, DrugBank
GABRA4 2557 BUTABARBITAL CHEMBL449 TdgClinicalTrial, TEND
GABRA4 2557 METHOXYFLURANE CHEMBL1341 ChemblInteractions
GABRA4 2557 CLORAZEPATE DIPOTASSIUM CHEMBL2096631 positive allosteric modulator ChemblInteractions
GABRA4 2557 CHLORDIAZEPOXIDE CHEMBL451 positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND
GABRA4 2557 DESFLURANE CHEMBL1200733 positive allosteric modulator ChemblInteractions
GABRA4 2557 HALAZEPAM CHEMBL970 positive allosteric modulator ChemblInteractions
GABRA4 2557 PENTOBARBITAL CHEMBL448 positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND
GABRA4 2557 CLOBAZAM CHEMBL70418 positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND
GABRA4 2557 OCINAPLON CHEMBL2105199 TdgClinicalTrial
GABRA4 2557 MIDAZOLAM CHEMBL655 TdgClinicalTrial, TEND
GABRA4 2557 ETHCHLORVYNOL CHEMBL591 ChemblInteractions
GABRA4 2557 THIOPENTAL SODIUM CHEMBL738 positive allosteric modulator ChemblInteractions
GABRA4 2557 GABOXADOL CHEMBL312443 agonist TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions
GABRA4 2557 BUTALBITAL CHEMBL454 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 10209232
GABRA4 2557 METHARBITAL CHEMBL450 potentiator, positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 10209232
GABRA4 2557 AMOBARBITAL CHEMBL267894 potentiator DrugBank 10209232
GABRA4 2557 HEPTABARBITAL CHEMBL468837 potentiator DrugBank 10209232
GABRA4 2557 BARBITAL CHEMBL444 potentiator DrugBank 10209232
GABRA4 2557 ALPRAZOLAM CHEMBL661 positive allosteric modulator TdgClinicalTrial, ChemblInteractions, TEND
GABRA4 2557 ENFLURANE CHEMBL1257 ChemblInteractions
GABRA4 2557 MIDAZOLAM HYDROCHLORIDE CHEMBL1200420 positive allosteric modulator ChemblInteractions
GABRA4 2557 SEVOFLURANE CHEMBL1200694 positive allosteric modulator ChemblInteractions
GABRA4 2557 THIAMYLAL SODIUM CHEMBL1201065 positive allosteric modulator ChemblInteractions
GABRA4 2557 CLORAZEPIC ACID CHEMBL1213252 TdgClinicalTrial, TEND
GABRA4 2557 PROPOFOL CHEMBL526 positive allosteric modulator ChemblInteractions

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID