PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
EED	1	MTF2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hauri S (2016), Hauri S (2016)	3
RELA	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Zhong H (2002), Zhong H (2002), Zhong H (2002), Zhong H (2002), Ashburner BP (2001), Ashburner BP (2001), OShea JM (2010), OShea JM (2010), Liu Y (2006), Cao W (2006), Hu J (2004), Hu J (2004), Sun JM (2007), Deckmann K (2012)	15
SUZ12	0	HNF4A	2	affinity chromatography technology, affinity chromatography technology	Englert NA (2015), Englert NA (2015)	2
LCOR	4	PHF1	1	affinity chromatography technology	Hauri S (2016)	1
RBBP7	1	EED	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	5
LCOR	4	EZH1	1	affinity chromatography technology	Hauri S (2016)	1
WT1	1	EZH2	4	affinity chromatography technology, affinity chromatography technology	Xu B (2011), Xu B (2011)	2
TRIM25	5	HIST1H1C	2	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
PHF19	3	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ballare C (2012), Hauri S (2016), Hauri S (2016)	3
MDM2	2	SIRT1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology	Nihira NT (2017), Nihira NT (2017), Nihira NT (2017)	3
SUZ12	0	CDK8	1	pull down, pull down	Fukasawa R (2012), Fukasawa R (2012)	2
PHF1	1	RBBP4	3	affinity chromatography technology, affinity chromatography technology	Cai L (2013), Hauri S (2016)	2
ELAVL1	0	EWSR1	2	affinity chromatography technology	Abdelmohsen K (2009)	1
EZH2	4	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	van der Vlag J (1999), van der Vlag J (1999), Caretti G (2004), Tong ZT (2012), Tong ZT (2012), Su L (2012), Su L (2012), Wan C (2015)	8
LCOR	4	MTF2	4	affinity chromatography technology	Hauri S (2016)	1
SUZ12	0	EPOP	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	3
RBBP4	3	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang Y (2003), Hakimi MA (2003), Zhang Y (2002), Tong JK (1998), Sun JM (2007), Sun JM (2007), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Wan C (2015), Hauri S (2016)	14
RELA	1	SUZ12	0	affinity chromatography technology, affinity chromatography technology	Lee ST (2011), Cao Q (2014)	2
EPOP	0	EZH1	1	affinity chromatography technology, affinity chromatography technology	Hauri S (2016), Hauri S (2016)	2
HIST1H1C	2	EED	1	pull down, affinity chromatography technology	Martin C (2006), Cao Q (2014)	2
EPOP	0	MTF2	4	affinity chromatography technology, affinity chromatography technology	Hauri S (2016), Hauri S (2016)	2
TRIM25	5	ELAVL1	0	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
ELAVL1	0	JARID2	7	affinity chromatography technology	Abdelmohsen K (2009)	1
RELA	1	EZH2	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Lee ST (2011), Lee ST (2011), Lee ST (2011), Lee ST (2011)	4
EWSR1	2	TRIM37	7	two hybrid	Rual JF (2005)	1
PHF19	3	EZH1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	3
JARID2	7	EZH1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pasini D (2010), Pasini D (2010), Hauri S (2016), Hauri S (2016)	4
MDM2	2	GTF2I	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Okoro DR (2013), Jacob AG (2014), Cetkovska K (2015), Cetkovska K (2015)	4
UBE2I	0	HDAC1	4	enzymatic study	Citro S (2013)	1
EPOP	0	HDAC2	1	affinity chromatography technology	Hauri S (2016)	1
HDAC1	4	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology	Hakimi MA (2002), Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Fischle W (2002), Johnson CA (2002), Fischle W (2001), Fischer DD (2002), Fischer DD (2002), Ashburner BP (2001), Zhang Y (1999), Tong JK (1998), Tong JK (1998), Hassig CA (1998), Hassig CA (1998), Zhang Y (1997), van der Vlag J (1999), van der Vlag J (1999), Noh EJ (2009), Noh EJ (2009), Galasinski SC (2002), Galasinski SC (2002), Galasinski SC (2002), He S (2005), Humphrey GW (2001), Park JH (2004), Park JH (2004), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Martinez FP (2012), Martinez FP (2012), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Joshi P (2013), Schnur N (2007), Schnur N (2007), Oh YM (2009), Wan C (2015), Hein MY (2015), Chen TC (2014), Huttlin EL (2017)	48
MDM2	2	EZH2	4	affinity chromatography technology, affinity chromatography technology	Wienken M (2016), Wienken M (2016)	2
JARID2	7	AEBP2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pasini D (2010), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	5
ELAVL1	0	TRIM37	7	affinity chromatography technology	Abdelmohsen K (2009)	1
EWSR1	2	SUZ12	0	two hybrid, affinity chromatography technology	Ravasi T (2010), Cao Q (2014)	2
SUZ12	0	LCOR	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Hauri S (2016)	2
UBE2I	0	GTF2I	1	enzymatic study	Gocke CB (2005)	1
CDK19	1	CTCF	15	biochemical	Havugimana PC (2012)	1
BTRC	1	EZH2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sahasrabuddhe AA (2014), Sahasrabuddhe AA (2014), Huttlin EL (2017)	3
EZH2	4	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cao Q (2014), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	6
BTRC	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down	Inuzuka H (2010), Inuzuka H (2010), Inuzuka H (2010)	3
PHF1	1	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hong Z (2008), Sarma K (2008), Hauri S (2016)	3
EZH2	4	HNF4A	2	affinity chromatography technology, affinity chromatography technology	Englert NA (2015), Englert NA (2015)	2
HNF4A	2	SIRT1	3	affinity chromatography technology	Chanda D (2010)	1
TRIM25	5	DDX5	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017), Choudhury NR (2017)	3
EED	1	EPOP	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hauri S (2016), Hauri S (2016)	3
EZH2	4	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	van der Vlag J (1999), van der Vlag J (1999), Tong ZT (2012), Tong ZT (2012), Wan C (2015)	5
PHF1	1	EZH2	4	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	OConnell S (2001), Hong Z (2008), Sarma K (2008), Cao Q (2014), Cai L (2013), Cai L (2013), Hein MY (2015), Hauri S (2016), Hauri S (2016)	9
SUZ12	0	PHF19	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cao Q (2014), Ballare C (2012), Ballare C (2012), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	6
ELAVL1	0	SUZ12	0	affinity chromatography technology, affinity chromatography technology	Abdelmohsen K (2009), Cao Q (2014)	2
EPOP	0	RBBP7	1	affinity chromatography technology, affinity chromatography technology	Hauri S (2016), Hauri S (2016)	2
MTF2	4	RBBP4	3	affinity chromatography technology, affinity chromatography technology	Hauri S (2016), Hauri S (2016)	2
EZH2	4	JARID2	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li G (2010), Li G (2010), Li G (2010), Li G (2010), Pasini D (2010), Pasini D (2010), Pasini D (2010), Cao Q (2014), Hein MY (2015), Hauri S (2016), Hauri S (2016)	11
BTRC	1	AEBP2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Loveless TB (2015), Loveless TB (2015), Huttlin EL (2017)	3
PHF1	1	HDAC1	4	affinity chromatography technology	Cai L (2013)	1
MDM2	2	RELA	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Wang J (2011), Heyne K (2013), Heyne K (2013), Heyne K (2013)	4
EED	1	AEBP2	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cao R (2004), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	6
SIRT1	3	RELA	1	affinity chromatography technology	Yang SR (2007)	1
EZH1	1	RBBP7	1	affinity chromatography technology	Hauri S (2016)	1
FBXW11	2	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Suzuki H (2000), Suzuki H (2000), Sowa ME (2009), Sowa ME (2009), Coyaud E (2015), Coyaud E (2015), Coyaud E (2015), Huttlin EL (2017), Liu X (2017)	9
SIRT1	3	SUZ12	0	affinity chromatography technology, affinity chromatography technology	Kuzmichev A (2005), OHagan HM (2011)	2
EED	1	DDX5	2	affinity chromatography technology, affinity chromatography technology	Cao Q (2014), Zhang H (2016)	2
EWSR1	2	HDAC2	1	biochemical	Havugimana PC (2012)	1
EZH1	1	MTF2	4	affinity chromatography technology, affinity chromatography technology	Hauri S (2016), Hauri S (2016)	2
PHF1	1	EED	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sarma K (2008), Cai L (2013), Hein MY (2015), Hauri S (2016), Hauri S (2016)	5
MTF2	4	SUZ12	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li G (2010), Cao Q (2014), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	5
MDM2	2	EED	1	affinity chromatography technology	Wienken M (2016)	1
UBE2I	0	MDM2	2	pull down, affinity chromatography technology, enzymatic study, unspecified method	Buschmann T (2001), Buschmann T (2001), Buschmann T (2001), Buschmann T (2001)	4
MTF2	4	26148	0	affinity chromatography technology	Hauri S (2016)	1
MTF2	4	JARID2	7	affinity chromatography technology, affinity chromatography technology	Li G (2010), Hauri S (2016)	2
RBBP7	1	MTF2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	4
RBBP4	3	RBBP7	1	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	7
26148	0	EED	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015), Hauri S (2016)	3
EED	1	RBBP4	3	biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pasini D (2004), Cao R (2004), Hein MY (2015), Hauri S (2016), Hauri S (2016)	5
LCOR	4	EZH2	4	affinity chromatography technology	Hauri S (2016)	1
FBXW11	2	ELAVL1	0	affinity chromatography technology	Low TY (2014)	1
TRIM25	5	MDM2	2	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	CTCF	15	affinity chromatography technology	Choudhury NR (2017)	1
EED	1	HNF4A	2	affinity chromatography technology, affinity chromatography technology	Englert NA (2015), Englert NA (2015)	2
EZH1	1	26148	0	affinity chromatography technology	Hauri S (2016)	1
HDAC1	4	GTF2I	1	affinity chromatography technology	Wen YD (2003)	1
ELAVL1	0	AEBP2	1	affinity chromatography technology	Abdelmohsen K (2009)	1
ELAVL1	0	BTRC	1	affinity chromatography technology, affinity chromatography technology	Chu PC (2012), Chu PC (2012)	2
FBXW11	2	EED	1	affinity chromatography technology	Huttlin EL (2017)	1
JARID2	7	HDAC2	1	affinity chromatography technology	Pasini D (2010)	1
ELAVL1	0	HDAC2	1	affinity chromatography technology	Abdelmohsen K (2009)	1
ELAVL1	0	MTF2	4	affinity chromatography technology	Abdelmohsen K (2009)	1
SUZ12	0	DDX5	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cao Q (2014), Zhang H (2016), Zhang H (2016), Zhang H (2016)	4
LCOR	4	HDAC1	4	pull down	Fernandes I (2003)	1
FBXW11	2	RELA	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim TY (2014), Coyaud E (2015), Huttlin EL (2017)	3
EWSR1	2	SIRT1	3	bioid	Elzi DJ (2014)	1
SUZ12	0	TRIM25	5	affinity chromatography technology, affinity chromatography technology	Cao Q (2014), Choudhury NR (2017)	2
HDAC2	1	SUZ12	0	biochemical, affinity chromatography technology, biochemical	Havugimana PC (2012), Pasini D (2010), Wan C (2015)	3
UBE2I	0	SUZ12	0	pull down, affinity chromatography technology	Riising EM (2008), Riising EM (2008)	2
HIST1H1C	2	AEBP2	1	pull down	Martin C (2006)	1
EED	1	GTF2I	1	affinity chromatography technology	Cao Q (2014)	1
AEBP2	1	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	3
EZH2	4	TRIM25	5	affinity chromatography technology	Cao Q (2014)	1
EZH2	4	MTF2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li G (2010), Li G (2010), Li G (2010), Cao Q (2014), Hauri S (2016), Hauri S (2016)	6
SUZ12	0	26148	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cao Q (2014), Huttlin EL (2017), Hauri S (2016)	3
EED	1	SUZ12	0	biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pasini D (2004), Cao R (2004), Margueron R (2008), Margueron R (2008), Shen X (2008), Pasini D (2008), Sarma K (2008), Pasini D (2010), Pasini D (2010), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Hein MY (2015), Chan YS (2013), Huttlin EL (2017), Zhang H (2016), Zhang H (2016), Wang X (2017), Hauri S (2016), Hauri S (2016)	22
EED	1	HDAC2	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	van der Vlag J (1999), van der Vlag J (1999), van der Vlag J (1999), van der Vlag J (1999), van der Vlag J (1999), Cao Q (2014)	6
EWSR1	2	GTF2I	1	affinity chromatography technology	Elzi DJ (2014)	1
MDM2	2	SUZ12	0	affinity chromatography technology, affinity chromatography technology	Wienken M (2016), Wienken M (2016)	2
LCOR	4	PHF19	3	affinity chromatography technology	Hauri S (2016)	1
EZH2	4	SUZ12	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Su IH (2005), Aoto T (2008), Hansen KH (2008), Li G (2010), Margueron R (2008), Margueron R (2008), Shen X (2008), Pasini D (2008), Pasini D (2008), Sarma K (2008), Xu B (2011), Xu B (2011), Avdic V (2011), Kaneko S (2010), Kaneko S (2010), Yap DB (2011), Lee ST (2011), Havugimana PC (2012), Sahasrabuddhe AA (2014), Wang L (2013), Wu L (2013), Pasini D (2010), Pasini D (2010), Pasini D (2010), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Wan C (2015), Hein MY (2015), Bhatnagar S (2014), Bhatnagar S (2014), Zhao R (2015), Wienken M (2016), Huttlin EL (2017), Zhang H (2016), Zhang H (2016), Mahara S (2016), Hauri S (2016), Hauri S (2016)	40
PHF1	1	EZH1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cai L (2013), Hauri S (2016), Hauri S (2016)	3
FBXW11	2	AEBP2	1	affinity chromatography technology, affinity chromatography technology	Kim TY (2014), Low TY (2014)	2
PHF19	3	PHF1	1	affinity chromatography technology	Hauri S (2016)	1
ELAVL1	0	PHF1	1	affinity chromatography technology	Abdelmohsen K (2009)	1
CDK19	1	WDR77	2	affinity chromatography technology, affinity chromatography technology, pull down	Tsutsui T (2013), Tsutsui T (2013), Tsutsui T (2013)	3
WT1	1	UBE2I	0	two hybrid, pull down, affinity chromatography technology	Wang ZY (1996), Wang ZY (1996), Wang ZY (1996)	3
EZH2	4	AEBP2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cao Q (2014), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	6
HIST1H1C	2	SUZ12	0	pull down, affinity chromatography technology	Martin C (2006), Cao Q (2014)	2
TRIM37	7	SUZ12	0	biochemical, affinity chromatography technology, affinity chromatography technology	Bhatnagar S (2014), Bhatnagar S (2014), Bhatnagar S (2014)	3
EED	1	CTCF	15	affinity chromatography technology	Cao Q (2014)	1
HDAC2	1	GTF2I	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hakimi MA (2003), Hakimi MA (2003), Hakimi MA (2003), Wen YD (2003)	4
BTRC	1	SUZ12	0	affinity chromatography technology, affinity chromatography technology	Sahasrabuddhe AA (2014), Huttlin EL (2017)	2
LCOR	4	EED	1	affinity chromatography technology	Hauri S (2016)	1
CDK8	1	CDK19	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EZH1	1	EZH2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Margueron R (2008), Margueron R (2008), Shen X (2008)	3
HDAC1	4	MDM2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Ito A (2002), Ito A (2002), Ito A (2002), Gaughan L (2005), Gaughan L (2005)	5
SUZ12	0	WDR77	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Furuno K (2006), Furuno K (2006), Furuno K (2006), Patel SR (2012)	4
RELA	1	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Spencer E (1999), Spencer E (1999), Coyaud E (2015), Coyaud E (2015), Huttlin EL (2017)	5
CDK8	1	WDR77	2	affinity chromatography technology, affinity chromatography technology, pull down	Tsutsui T (2013), Tsutsui T (2013), Tsutsui T (2013)	3
ELAVL1	0	RBBP4	3	affinity chromatography technology	Abdelmohsen K (2009)	1
SUZ12	0	HDAC1	4	affinity chromatography technology, biochemical	Cao Q (2014), Wan C (2015)	2
CTCF	15	SUZ12	0	affinity chromatography technology, pull down, two hybrid, pull down	Li T (2008), Li T (2008), Li T (2008), Zhang H (2011)	4
EPOP	0	RBBP4	3	affinity chromatography technology	Hauri S (2016)	1
PHF1	1	26148	0	affinity chromatography technology	Hauri S (2016)	1
RELA	1	HDAC2	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Kiernan R (2003), Yu Z (2002), Yu Z (2002), Ito K (2001), Ito K (2000), Sun JM (2007), Adenuga D (2010), Wang H (2010), Chen TC (2014)	9
HDAC1	4	DDX5	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wilson BJ (2004), Wilson BJ (2004), Guo J (2010), Jacobs AM (2007), Mooney SM (2010), Mooney SM (2010)	6
EZH1	1	EED	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Margueron R (2008), Margueron R (2008), Shen X (2008), Jones CA (1998), van Lohuizen M (1998), Wang X (2017), Hauri S (2016), Hauri S (2016)	8
EZH2	4	RBBP4	3	affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li G (2010), Kaneko S (2010), Kaneko S (2010), Cao Q (2014), Hein MY (2015), Hauri S (2016), Hauri S (2016)	7
EWSR1	2	26148	0	two hybrid	Rual JF (2005)	1
SUZ12	0	GTF2I	1	affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Cao Q (2014)	2
PHF19	3	EZH2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Boulay G (2011), Cao Q (2014), Ballare C (2012), Ballare C (2012), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	7
EZH2	4	SIRT1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Kuzmichev A (2005), Kuzmichev A (2005), OHagan HM (2011), Wan J (2015), Wan J (2015), Wan J (2015)	6
MDM2	2	HNF4A	2	affinity chromatography technology, affinity chromatography technology	Yang Z (2012), Yang Z (2012)	2
JARID2	7	SUZ12	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li G (2010), Pasini D (2010), Pasini D (2010), Pasini D (2010), Pasini D (2010), Cao Q (2014), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	9
EZH2	4	EED	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, pull down, pull down, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	van Lohuizen M (1998), van Lohuizen M (1998), van Lohuizen M (1998), van der Vlag J (1999), van der Vlag J (1999), van der Vlag J (1999), Denisenko O (1998), Denisenko O (1998), Denisenko O (1998), Denisenko O (1998), Pasini D (2004), Cao R (2004), Su IH (2005), Hansen KH (2008), Margueron R (2008), Margueron R (2008), Shen X (2008), Shen X (2008), Hernandez-Munoz I (2005), Sarma K (2008), Sarma K (2008), Han Z (2007), Avdic V (2011), Kaneko S (2010), Kaneko S (2010), Yap DB (2011), Satijn DP (2001), Satijn DP (2001), Sewalt RG (1998), Sewalt RG (1998), Sewalt RG (1998), Sewalt RG (1998), Wang L (2013), Wu L (2013), Pasini D (2010), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Wan C (2015), Hein MY (2015), Hein MY (2015), Chan YS (2013), Zhang H (2016), Zhang H (2016), Wang X (2017), Hauri S (2016), Hauri S (2016)	49
AEBP2	1	EZH1	1	affinity chromatography technology, affinity chromatography technology	Hauri S (2016), Hauri S (2016)	2
ELAVL1	0	SIRT1	3	affinity chromatography technology	Abdelmohsen K (2009)	1
WT1	1	SUZ12	0	affinity chromatography technology, affinity chromatography technology	Xu B (2011), Xu B (2011)	2
UBE2I	0	DDX5	2	enzymatic study	Matafora V (2009)	1
JARID2	7	RBBP7	1	affinity chromatography technology, affinity chromatography technology	Pasini D (2010), Hauri S (2016)	2
LCOR	4	RBBP7	1	affinity chromatography technology	Hauri S (2016)	1
TRIM25	5	BTRC	1	affinity chromatography technology	Choudhury NR (2017)	1
EZH2	4	EPOP	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hauri S (2016), Hauri S (2016)	3
LCOR	4	RBBP4	3	affinity chromatography technology	Hauri S (2016)	1
MDM2	2	DDX5	2	affinity chromatography technology	Okoro DR (2013)	1
HDAC2	1	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Hakimi MA (2003), Adenuga D (2010), Xue Y (1998), Havugimana PC (2012), Bantscheff M (2011), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Hauri S (2016)	9
SIRT1	3	EED	1	affinity chromatography technology	OHagan HM (2011)	1
EZH2	4	26148	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cao Q (2014), Hein MY (2015), Hauri S (2016)	3
SUZ12	0	RBBP4	3	pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cao R (2004), Cao R (2004), Havugimana PC (2012), Pasini D (2010), Cao Q (2014), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	8
RBM5	0	WDR77	2	two hybrid, two hybrid	Hegele A (2012), Hegele A (2012)	2
FBXW11	2	MDM2	2	affinity chromatography technology	Inuzuka H (2010)	1
TRIM37	7	EZH2	4	biochemical, affinity chromatography technology, affinity chromatography technology, imaging technique	Bhatnagar S (2014), Bhatnagar S (2014), Bhatnagar S (2014), Bhatnagar S (2014)	4
PHF19	3	RBM5	0	affinity chromatography technology	Huttlin EL (2015)	1
EED	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	van der Vlag J (1999), van der Vlag J (1999), van der Vlag J (1999), Hein MY (2015)	4
SUZ12	0	AEBP2	1	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cao R (2004), Cao R (2004), Pasini D (2010), Cao Q (2014), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	8
JARID2	7	EED	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pasini D (2010), Pasini D (2010), Hein MY (2015), Hauri S (2016), Hauri S (2016)	5
SIRT1	3	HDAC2	1	affinity chromatography technology	Law IK (2009)	1
PHF19	3	RBBP4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ballare C (2012), Hauri S (2016), Hauri S (2016)	3
FBXW11	2	SUZ12	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim TY (2014), Low TY (2014), Huttlin EL (2017)	3
EPOP	0	PHF1	1	affinity chromatography technology	Hauri S (2016)	1
TRIM25	5	WDR77	2	affinity chromatography technology	Choudhury NR (2017)	1
EZH2	4	DDX5	2	affinity chromatography technology, affinity chromatography technology	Cao Q (2014), Zhang H (2016)	2
FBXW11	2	RBM5	0	affinity chromatography technology	Low TY (2014)	1
RBBP4	3	AEBP2	1	pull down, affinity chromatography technology, affinity chromatography technology	Cao R (2004), Hauri S (2016), Hauri S (2016)	3
BTRC	1	EED	1	affinity chromatography technology	Huttlin EL (2017)	1
HDAC1	4	RBBP7	1	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yao YL (2003), Ng HH (1999), Zhang Y (1999), Zhang Y (1997), Banach-Orlowska M (2009), Humphrey GW (2001), Zhang Y (1998), Zhang Y (1998), Xue Y (1998), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Yeh HH (2015), Yeh HH (2015), Huttlin EL (2017), Hauri S (2016)	19
JARID2	7	RBBP4	3	affinity chromatography technology, affinity chromatography technology	Pasini D (2010), Hauri S (2016)	2
RBBP4	3	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Yao YL (2003), Nicolas E (2001), Nicolas E (2001), Grozinger CM (1999), You A (2001), Hassig CA (1997), Hassig CA (1997), Ng HH (1999), Zhang Y (1999), Zhang Y (2002), Hassig CA (1998), Zhang Y (1997), Banach-Orlowska M (2009), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Humphrey GW (2001), Zhang Y (1998), Zhang Y (1998), Sun JM (2007), Sun JM (2007), Karwowska-Desaulniers P (2007), Terhune SS (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Hauri S (2016)	35
PHF19	3	EED	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Boulay G (2011), Ballare C (2012), Ballare C (2012), Hein MY (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	7
SUZ12	0	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pasini D (2010), Cao Q (2014), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	6
EWSR1	2	EZH2	4	two hybrid, affinity chromatography technology	Ravasi T (2010), Cao Q (2014)	2
FBXW11	2	GTF2I	1	affinity chromatography technology	Low TY (2014)	1
EZH1	1	RBBP4	3	affinity chromatography technology	Hauri S (2016)	1
CDK19	1	SUZ12	0	two hybrid, pull down, pull down	Fukasawa R (2012), Fukasawa R (2012), Fukasawa R (2012)	3
PHF1	1	SUZ12	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hong Z (2008), Sarma K (2008), Cao Q (2014), Cai L (2013), Cai L (2013), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	8
PHF19	3	26148	0	affinity chromatography technology	Hauri S (2016)	1
EPOP	0	PHF19	3	affinity chromatography technology, affinity chromatography technology	Hauri S (2016), Hauri S (2016)	2
DDX5	2	HDAC2	1	affinity chromatography technology, affinity chromatography technology	Mooney SM (2010), Mooney SM (2010)	2
MDM2	2	WT1	1	two hybrid	Wang J (2011)	1
EZH2	4	ELAVL1	0	affinity chromatography technology	Cao Q (2014)	1
FBXW11	2	EZH2	4	affinity chromatography technology, affinity chromatography technology	Kim TY (2014), Low TY (2014)	2
TRIM25	5	RBBP4	3	affinity chromatography technology	Choudhury NR (2017)	1
EZH1	1	SUZ12	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Margueron R (2008), Margueron R (2008), Shen X (2008), Pasini D (2010), Cao Q (2014), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	8
HNF4A	2	UBE2I	0	two hybrid, enzymatic study	Albers M (2005), Zhou W (2012)	2
EED	1	ELAVL1	0	affinity chromatography technology	Cao Q (2014)	1
SIRT1	3	UBE2I	0	enzymatic study	Hsieh YL (2013)	1
SUZ12	0	RBM5	0	affinity chromatography technology, affinity chromatography technology	Cao Q (2014), Huttlin EL (2017)	2