PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
KIAA0753	1	HAUS6	5	bioid	Gupta GD (2015)	1
CEP44	2	HAUS8	2	bioid	Gupta GD (2015)	1
HAUS7	0	HAUS8	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RAB5C	2	HAUS5	0	affinity chromatography technology	Hein MY (2015)	1
CEP162	3	HAUS6	5	bioid	Gupta GD (2015)	1
MED4	2	NIN	4	bioid	Lambert JP (2015)	1
SYCE3	0	NIN	4	affinity chromatography technology	Huttlin EL (2017)	1
CEP250	4	SPICE1	2	affinity chromatography technology	Fogeron ML (2013)	1
ODF2	1	KIAA0753	1	bioid	Gupta GD (2015)	1
MED4	2	HAUS6	5	bioid	Lambert JP (2015)	1
CEP120	5	MED4	2	bioid	Gupta GD (2015)	1
MED4	2	KIAA0753	1	bioid, bioid	Lambert JP (2015), Gupta GD (2015)	2
KIAA0753	1	POC5	5	bioid, bioid	Firat-Karalar EN (2014), Gupta GD (2015)	2
CDC16	2	HAUS5	0	affinity chromatography technology	Huttlin EL (2017)	1
OFD1	3	HAUS8	2	bioid	Gupta GD (2015)	1
XPO1	8	HAUS5	0	affinity chromatography technology	Kirli K (2015)	1
HAUS2	2	HAUS8	2	affinity chromatography technology	Hein MY (2015)	1
USP43	1	HAUS5	0	affinity chromatography technology	Hein MY (2015)	1
NINL	1	HAUS7	0	bioid	Gupta GD (2015)	1
CEP128	1	HAUS5	0	bioid	Gupta GD (2015)	1
CNTRL	5	HAUS2	2	bioid	Gupta GD (2015)	1
CEP120	5	HAUS5	0	bioid	Gupta GD (2015)	1
CNTRL	5	HAUS8	2	bioid	Gupta GD (2015)	1
CEP89	2	HAUS8	2	bioid	Gupta GD (2015)	1
NIN	4	HAUS5	0	bioid	Gupta GD (2015)	1
CDC16	2	HAUS8	2	affinity chromatography technology	Huttlin EL (2017)	1
HAUS7	0	HAUS5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CEP89	2	MED4	2	bioid	Gupta GD (2015)	1
SPICE1	2	HAUS6	5	bioid	Gupta GD (2015)	1
MED4	2	PCM1	5	bioid, affinity chromatography technology, affinity chromatography technology, bioid	Lambert JP (2015), Lambert JP (2015), Gupta GD (2015), Gupta GD (2015)	4
CCDC8	1	PCM1	5	affinity chromatography technology	Hanson D (2014)	1
POC5	5	MED4	2	bioid	Gupta GD (2015)	1
SYCE3	0	SASS6	1	affinity chromatography technology	Huttlin EL (2017)	1
CNTRL	5	HAUS6	5	bioid	Gupta GD (2015)	1
KIAA0753	1	CEP44	2	bioid	Gupta GD (2015)	1
CEP120	5	HAUS6	5	bioid	Gupta GD (2015)	1
RFXANK	0	HAUS5	0	affinity chromatography technology	Huttlin EL (2017)	1
IL17RA	3	HAUS5	0	affinity chromatography technology	Huttlin EL (2017)	1
NTRK1	1	OFD1	3	affinity chromatography technology	Emdal KB (2015)	1
NIN	4	HAUS6	5	bioid	Gupta GD (2015)	1
HAUS2	2	HAUS6	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uehara R (2009), Uehara R (2009), Fogeron ML (2013), Hein MY (2015)	4
YAE1D1	1	HAUS5	0	two hybrid	Vinayagam A (2011)	1
SASS6	1	HAUS5	0	bioid	Gupta GD (2015)	1
SPICE1	2	HAUS7	0	bioid	Gupta GD (2015)	1
CEP89	2	HAUS6	5	bioid	Gupta GD (2015)	1
CEP44	2	HAUS7	0	bioid	Gupta GD (2015)	1
OFD1	3	HAUS2	2	bioid	Gupta GD (2015)	1
SPICE1	2	PCM1	5	affinity chromatography technology, bioid, bioid, affinity chromatography technology	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Huttlin EL (2017)	4
ODF2	1	HAUS7	0	bioid	Gupta GD (2015)	1
SPICE1	2	HAUS5	0	bioid	Gupta GD (2015)	1
CEP128	1	NINL	1	bioid	Gupta GD (2015)	1
HAUS2	2	HAUS7	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
PCM1	5	CEP120	5	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
CEP128	1	CEP120	5	bioid	Gupta GD (2015)	1
NTRK1	1	XPO1	8	affinity chromatography technology	Emdal KB (2015)	1
CEP162	3	OFD1	3	affinity chromatography technology, affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
ILK	0	XPO1	8	affinity chromatography technology	So J (2015)	1
SASS6	1	OFD1	3	bioid	Gupta GD (2015)	1
CNTRL	5	KIAA0753	1	bioid	Gupta GD (2015)	1
SPICE1	2	CEP44	2	bioid	Gupta GD (2015)	1
CEP128	1	PCM1	5	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
CCDC8	1	XPO1	8	affinity chromatography technology	Hanson D (2014)	1
HAUS5	0	HAUS6	5	affinity chromatography technology, two hybrid, affinity chromatography technology	Uehara R (2009), Uehara R (2009), Uehara R (2009)	3
SYCE3	0	HAUS2	2	affinity chromatography technology	Huttlin EL (2017)	1
CEP128	1	SPICE1	2	bioid	Gupta GD (2015)	1
NIN	4	HAUS7	0	bioid	Gupta GD (2015)	1
PCM1	5	KIAA0753	1	affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
HAUS2	2	HAUS5	0	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Hein MY (2015)	2
CDC16	2	HAUS6	5	affinity chromatography technology	Huttlin EL (2017)	1
EGLN3	0	HAUS2	2	affinity chromatography technology	Rodriguez J (2016)	1
NIN	4	PCM1	5	bioid	Gupta GD (2015)	1
SASS6	1	HAUS8	2	bioid	Gupta GD (2015)	1
EGLN3	0	XPO1	8	affinity chromatography technology	Rodriguez J (2016)	1
PCM1	5	HAUS6	5	bioid	Gupta GD (2015)	1
CEP250	4	PCM1	5	affinity chromatography technology	Fogeron ML (2013)	1
PCM1	5	HAUS5	0	bioid	Gupta GD (2015)	1
CEP63	2	CEP44	2	bioid	Gupta GD (2015)	1
POC5	5	HAUS7	0	bioid	Gupta GD (2015)	1
NINL	1	HAUS6	5	bioid	Gupta GD (2015)	1
HAUS8	2	HAUS6	5	affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology	Uehara R (2009), Uehara R (2009), Uehara R (2009), Uehara R (2009)	4
OFD1	3	NIN	4	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
ILK	0	HAUS5	0	affinity chromatography technology	Varjosalo M (2013)	1
HAUS7	0	HAUS6	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uehara R (2009), Uehara R (2009), Huttlin EL (2015), Huttlin EL (2017)	4
NINL	1	HAUS5	0	bioid	Gupta GD (2015)	1
EGLN3	0	HAUS5	0	affinity chromatography technology	Rodriguez J (2016)	1
CEP128	1	CEP162	3	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
SASS6	1	HAUS6	5	bioid	Gupta GD (2015)	1
RGS2	2	HAUS5	0	two hybrid	Vinayagam A (2011)	1
CEP89	2	HAUS5	0	bioid	Gupta GD (2015)	1
PCM1	5	HAUS8	2	bioid	Gupta GD (2015)	1
NINL	1	CEP162	3	bioid	Gupta GD (2015)	1
XPO1	8	HAUS8	2	affinity chromatography technology	Kirli K (2015)	1
CNTRL	5	HAUS7	0	bioid	Gupta GD (2015)	1
CEP162	3	CEP120	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	5
CEP63	2	CEP128	1	bioid, bioid, bioid	Firat-Karalar EN (2014), Gupta GD (2015), Gupta GD (2015)	3
PCM1	5	CEP89	2	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
CDC16	2	HAUS7	0	affinity chromatography technology	Huttlin EL (2017)	1
SPICE1	2	KIAA0753	1	bioid	Gupta GD (2015)	1
XPO1	8	HAUS7	0	affinity chromatography technology	Kirli K (2015)	1
XPO1	8	HAUS2	2	affinity chromatography technology	Kirli K (2015)	1
XPO1	8	HAUS6	5	affinity chromatography technology	Kirli K (2015)	1
SPICE1	2	HAUS8	2	bioid	Gupta GD (2015)	1
XPO1	8	POC5	5	affinity chromatography technology	Kirli K (2015)	1
CEP89	2	HAUS7	0	bioid	Gupta GD (2015)	1
ODF2	1	OFD1	3	bioid	Gupta GD (2015)	1
CEP128	1	OFD1	3	bioid, affinity chromatography technology	Gupta GD (2015), Hein MY (2015)	2
OFD1	3	HAUS6	5	bioid	Gupta GD (2015)	1
CEP162	3	HAUS8	2	bioid	Gupta GD (2015)	1
ODF2	1	HAUS6	5	bioid	Gupta GD (2015)	1
CEP63	2	SPICE1	2	bioid	Firat-Karalar EN (2014)	1
SPICE1	2	HAUS2	2	bioid	Gupta GD (2015)	1
CEP128	1	CEP89	2	bioid	Gupta GD (2015)	1
C6orf141	1	HAUS5	0	affinity chromatography technology	Huttlin EL (2017)	1
EGLN3	0	NIN	4	affinity chromatography technology	Rodriguez J (2016)	1
POC5	5	OFD1	3	bioid	Gupta GD (2015)	1
CEP128	1	MED4	2	bioid	Gupta GD (2015)	1
CNTRL	5	NIN	4	bioid	Gupta GD (2015)	1
EGLN3	0	ILK	0	affinity chromatography technology	Rodriguez J (2016)	1
CEP162	3	KIAA0753	1	affinity chromatography technology, affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
OFD1	3	PCM1	5	affinity chromatography technology, affinity chromatography technology, bioid, bioid, affinity chromatography technology	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Hein MY (2015)	5
CEP63	2	HAUS5	0	bioid	Gupta GD (2015)	1
XPO1	8	YAE1D1	1	affinity chromatography technology	Kirli K (2015)	1
ODF2	1	HAUS8	2	bioid	Gupta GD (2015)	1
OFD1	3	HAUS5	0	bioid	Gupta GD (2015)	1
NTRK1	1	PCM1	5	affinity chromatography technology	Emdal KB (2015)	1
POC5	5	HAUS2	2	bioid	Gupta GD (2015)	1
HAUS2	2	PCM1	5	affinity chromatography technology, bioid, affinity chromatography technology	Fogeron ML (2013), Gupta GD (2015), Hein MY (2015)	3
NINL	1	PCM1	5	bioid	Gupta GD (2015)	1
CNTRL	5	PCM1	5	bioid	Gupta GD (2015)	1
SPICE1	2	OFD1	3	bioid, affinity chromatography technology	Gupta GD (2015), Hein MY (2015)	2
MED4	2	OFD1	3	bioid	Lambert JP (2015)	1
CRYL1	0	HAUS5	0	affinity chromatography technology	Huttlin EL (2017)	1
CEP128	1	KIAA0753	1	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
SYCE3	0	CNTRL	5	affinity chromatography technology	Huttlin EL (2017)	1
CEP128	1	HAUS2	2	bioid	Gupta GD (2015)	1
ODF2	1	HAUS5	0	bioid	Gupta GD (2015)	1
SASS6	1	HAUS7	0	bioid	Gupta GD (2015)	1
CCDC8	1	HAUS5	0	affinity chromatography technology	Hanson D (2014)	1
SYCE3	0	HAUS5	0	affinity chromatography technology	Huttlin EL (2017)	1
PCM1	5	ODF2	1	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
LRIF1	3	HAUS5	0	affinity chromatography technology	Hein MY (2015)	1
NTRK1	1	RAB5C	2	affinity chromatography technology	Emdal KB (2015)	1
CEP162	3	SPICE1	2	affinity chromatography technology, affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	4
CEP44	2	HAUS6	5	bioid	Gupta GD (2015)	1
POC5	5	PCM1	5	bioid	Gupta GD (2015)	1
NINL	1	OFD1	3	bioid	Gupta GD (2015)	1
ODF2	1	CEP120	5	bioid	Gupta GD (2015)	1
CEP128	1	HAUS7	0	bioid	Gupta GD (2015)	1
MED4	2	HAUS2	2	bioid	Lambert JP (2015)	1
POC5	5	NIN	4	bioid	Gupta GD (2015)	1
CEP63	2	NIN	4	bioid	Firat-Karalar EN (2014)	1
CEP63	2	KIAA0753	1	bioid, bioid, affinity chromatography technology, bioid	Firat-Karalar EN (2014), Firat-Karalar EN (2014), Firat-Karalar EN (2014), Gupta GD (2015)	4
CEP128	1	CEP44	2	bioid	Gupta GD (2015)	1
CEP120	5	HAUS2	2	bioid	Gupta GD (2015)	1
NTRK1	1	HAUS6	5	affinity chromatography technology	Emdal KB (2015)	1
CEP120	5	OFD1	3	bioid	Gupta GD (2015)	1
KIAA0753	1	OFD1	3	bioid, bioid, bioid, affinity chromatography technology	Firat-Karalar EN (2014), Gupta GD (2015), Gupta GD (2015), Hein MY (2015)	4
NINL	1	CEP89	2	bioid	Gupta GD (2015)	1
C6orf141	1	OFD1	3	affinity chromatography technology	Huttlin EL (2017)	1
CNTRL	5	ODF2	1	bioid	Gupta GD (2015)	1
CEP63	2	OFD1	3	bioid, bioid, bioid	Firat-Karalar EN (2014), Gupta GD (2015), Gupta GD (2015)	3
MED4	2	HAUS5	0	bioid	Lambert JP (2015)	1
CEP162	3	CEP89	2	bioid	Gupta GD (2015)	1
CCDC8	1	RAB5C	2	affinity chromatography technology	Hanson D (2014)	1
CEP63	2	HAUS8	2	bioid	Gupta GD (2015)	1
KIAA0753	1	HAUS5	0	bioid	Gupta GD (2015)	1
KIAA0753	1	CEP120	5	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
NIN	4	HAUS8	2	bioid	Gupta GD (2015)	1
SASS6	1	HAUS2	2	bioid	Gupta GD (2015)	1
CEP128	1	HAUS6	5	bioid	Gupta GD (2015)	1
CEP89	2	OFD1	3	bioid	Gupta GD (2015)	1
HAUS8	2	HAUS5	0	two hybrid	Uehara R (2009)	1
MED4	2	HAUS7	0	bioid	Lambert JP (2015)	1
NINL	1	SASS6	1	bioid	Gupta GD (2015)	1
CEP128	1	HAUS8	2	bioid	Gupta GD (2015)	1
CEP120	5	HAUS8	2	bioid	Gupta GD (2015)	1
EGLN3	0	CCDC8	1	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	PCM1	5	affinity chromatography technology	Rodriguez J (2016)	1
CEP44	2	HAUS5	0	bioid	Gupta GD (2015)	1
POC5	5	CEP128	1	bioid	Gupta GD (2015)	1
CEP44	2	OFD1	3	bioid	Gupta GD (2015)	1
CEP128	1	CNTRL	5	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
C6orf141	1	HAUS7	0	affinity chromatography technology	Huttlin EL (2017)	1
CEP63	2	HAUS6	5	bioid	Gupta GD (2015)	1
MED4	2	HAUS8	2	bioid	Lambert JP (2015)	1
CEP162	3	HAUS2	2	bioid	Gupta GD (2015)	1
CEP63	2	MED4	2	bioid	Gupta GD (2015)	1
CNTRL	5	OFD1	3	bioid	Gupta GD (2015)	1
CEP250	4	CCDC8	1	affinity chromatography technology	Fogeron ML (2013)	1
POC5	5	HAUS6	5	bioid	Gupta GD (2015)	1
NINL	1	HAUS2	2	bioid	Gupta GD (2015)	1
CEP120	5	HAUS7	0	bioid	Gupta GD (2015)	1
OFD1	3	HAUS7	0	bioid	Gupta GD (2015)	1
PCM1	5	CEP63	2	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
CEP162	3	HAUS7	0	bioid	Gupta GD (2015)	1
CEP162	3	HAUS5	0	bioid	Gupta GD (2015)	1
PCM1	5	HAUS7	0	bioid	Gupta GD (2015)	1
KIAA0753	1	HAUS8	2	bioid	Gupta GD (2015)	1
IL17RA	3	LRIF1	3	affinity chromatography technology	Huttlin EL (2017)	1
CNTRL	5	MED4	2	bioid	Gupta GD (2015)	1
XPO1	8	SPICE1	2	affinity chromatography technology	Kirli K (2015)	1
TMOD4	0	HAUS5	0	affinity chromatography technology	Huttlin EL (2017)	1
RGS2	2	NINL	1	two hybrid, affinity chromatography technology	Rual JF (2005), Huttlin EL (2017)	2
ODF2	1	CEP44	2	bioid	Gupta GD (2015)	1
CNTRL	5	HAUS5	0	bioid	Gupta GD (2015)	1
CEP120	5	SPICE1	2	bioid, bioid, affinity chromatography technology	Gupta GD (2015), Gupta GD (2015), Huttlin EL (2017)	3
C6orf141	1	HAUS6	5	affinity chromatography technology	Huttlin EL (2017)	1
KIAA0753	1	HAUS2	2	bioid	Gupta GD (2015)	1
CNTRL	5	CEP89	2	bioid	Gupta GD (2015)	1
MED4	2	CEP162	3	bioid, affinity chromatography technology, bioid	Lambert JP (2015), Gupta GD (2015), Gupta GD (2015)	3
CEP89	2	KIAA0753	1	bioid	Gupta GD (2015)	1
CNKSR1	2	HAUS5	0	affinity chromatography technology	Huttlin EL (2017)	1
SASS6	1	MED4	2	bioid	Gupta GD (2015)	1
CEP128	1	NIN	4	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
NTRK1	1	HAUS5	0	affinity chromatography technology	Emdal KB (2015)	1
POC5	5	HAUS5	0	bioid	Gupta GD (2015)	1
CEP128	1	ODF2	1	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
PCM1	5	CEP162	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	5
EGLN3	0	HAUS7	0	affinity chromatography technology	Rodriguez J (2016)	1
CEP250	4	NINL	1	affinity chromatography technology	Fogeron ML (2013)	1
MED4	2	SPICE1	2	bioid, bioid	Lambert JP (2015), Gupta GD (2015)	2
CCDC8	1	OFD1	3	affinity chromatography technology	Hanson D (2014)	1
NINL	1	KIAA0753	1	bioid	Gupta GD (2015)	1
CEP250	4	HAUS5	0	affinity chromatography technology	Fogeron ML (2013)	1
SASS6	1	PCM1	5	bioid	Gupta GD (2015)	1
CEP89	2	HAUS2	2	bioid	Gupta GD (2015)	1
CNTRL	5	CEP162	3	bioid	Gupta GD (2015)	1
CEP63	2	HAUS7	0	bioid	Gupta GD (2015)	1
MED4	2	ODF2	1	bioid, bioid	Lambert JP (2015), Gupta GD (2015)	2
POC5	5	HAUS8	2	bioid	Gupta GD (2015)	1
EGLN3	0	HAUS6	5	affinity chromatography technology	Rodriguez J (2016)	1