Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
FGFR2 2263 JNJ-42756493 CHEMBL3545376 inhibitor OncoKB, CKB, GuideToPharmacologyInteractions, CIViC 26324363, 28341788, 24122810
FGFR2 2263 CHEMBL233209 CHEMBL233209 DrugBank 17139284, 17016423
FGFR2 2263 ARQ-087 CHEMBL3545421 inhibitor TdgClinicalTrial, CKB, ChemblInteractions
FGFR2 2263 TRAFERMIN CHEMBL2108081 activator TdgClinicalTrial, TTD
FGFR2 2263 DOVITINIB CHEMBL522892 inhibitor TALC, MyCancerGenome, TdgClinicalTrial, ClearityFoundationClinicalTrial, CKB, CGI, DoCM 23908597, 23658459, 26036639, 22238366, 23443805, 18552176, 23002168, 26619011
FGFR2 2263 LENVATINIB CHEMBL1289601 inhibitor TALC
FGFR2 2263 SELUMETINIB CHEMBL1614701 CKB 19755509, 26438159
FGFR2 2263 NINTEDANIB ESYLATE CHEMBL3039504 inhibitor ChemblInteractions
FGFR2 2263 BRIVANIB ALANINATE CHEMBL270995 inhibitor ChemblInteractions
FGFR2 2263 RG-1530 CHEMBL1980391 inhibitor ChemblInteractions
FGFR2 2263 TG100-801 CHEMBL403989 inhibitor ChemblInteractions
FGFR2 2263 PALIFERMIN CHEMBL1201821 agonist, binder TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, TEND, DrugBank, TTD 10593896, 16854582, 9056643, 16390600, 11752352, 17728847, 17456767, 7499435
FGFR2 2263 AZD-4547 CHEMBL3184679 inhibitor MyCancerGenomeClinicalTrial, GuideToPharmacologyInteractions, TALC, MyCancerGenome, CIViC, CKB, ChemblInteractions 27179038, 27595477, 26936917, 27401245, 27550940, 22869148, 26294741, 25169980, 26351320
FGFR2 2263 LY-2874455 CHEMBL3545264 inhibitor GuideToPharmacologyInteractions, ChemblInteractions
FGFR2 2263 MK-2461 CHEMBL1822792 inhibitor GuideToPharmacologyInteractions
FGFR2 2263 CHEMBL315546 CHEMBL315546 DrugBank 11752352
FGFR2 2263 PONATINIB CHEMBL1171837 inhibitor TALC, MyCancerGenome, CKB, CGI, CIViC, DrugBank, DoCM 23468082, 23908597, 18552176, 22238366, 23002168, 26619011, 24550739, 26574622, 26048680
FGFR2 2263 ENMD-2076 CHEMBL482968 TdgClinicalTrial, ClearityFoundationClinicalTrial
FGFR2 2263 AEE-788 CHEMBL587723 inhibitor TTD
FGFR2 2263 PENTOSAN POLYSULFATE SODIUM CHEMBL1201516 inhibitor TTD
FGFR2 2263 PD-173074 CHEMBL189584 CKB, CIViC 18757403, 24122810, 23908597, 27179038, 26036639, 22869148
FGFR2 2263 LAPATINIB CHEMBL554 CKB 27595477
FGFR2 2263 SUNITINIB CHEMBL535 CKB 27149458
FGFR2 2263 PICTILISIB CHEMBL521851 CKB 28119489
FGFR2 2263 INFIGRATINIB CHEMBL1852688 inhibitor OncoKB, CancerCommons, GuideToPharmacologyInteractions, TALC, MyCancerGenomeClinicalTrial, CIViC, CKB, ChemblInteractions 27216979, 24122810, 27870574, 28034880, 27401245, 26036639, 26048680, 28119489, 23443805, 24563622
FGFR2 2263 NINTEDANIB CHEMBL502835 inhibitor, Inhibitor TALC, MyCancerGenome, TdgClinicalTrial, ClearityFoundationClinicalTrial, CKB, GuideToPharmacologyInteractions, DrugBank 18559524, 22238366
FGFR2 2263 REGORAFENIB CHEMBL1946170 inhibitor ChemblInteractions, DrugBank, MyCancerGenomeClinicalTrial
FGFR2 2263 XL-228 CHEMBL3545085 inhibitor TALC, MyCancerGenome
FGFR2 2263 CEDIRANIB CHEMBL491473 CKB 22238366
FGFR2 2263 ALPELISIB CHEMBL2396661 CKB 28119489
FGFR2 2263 ENMD-981693 CHEMBL52885 inhibitor ChemblInteractions
FGFR2 2263 ORANTINIB CHEMBL274654 inhibitor ChemblInteractions
FGFR2 2263 XL-999 CHEMBL3545285 inhibitor ChemblInteractions
FGFR2 2263 INTERFERON ALFA-2A CHEMBL2108508 binder TTD
FGFR2 2263 MASITINIB CHEMBL1908391 inhibitor MyCancerGenome
FGFR2 2263 TRABECTEDIN CHEMBL1224207 CKB 26036639
FGFR2 2263 BRIVANIB CHEMBL377300 inhibitor CKB, ChemblInteractions 22238366
FGFR2 2263 CETUXIMAB CHEMBL1201577 CKB 27149458
FGFR2 2263 BUPARLISIB CHEMBL2017974 CKB 28119489
FGFR2 2263 CP-459632 CHEMBL3545300 inhibitor ChemblInteractions
FGFR2 2263 LUCITANIB CHEMBL2220486 inhibitor ChemblInteractions
FGFR2 2263 BAY-1163877 CHEMBL3545361 inhibitor ChemblInteractions
FGFR2 2263 PHA-665752 CHEMBL450786 CKB 26351320
FGFR2 2263 TRAMETINIB CHEMBL2103875 CKB 27338794
FGFR2 2263 PAZOPANIB CHEMBL477772 CIViC, DoCM 24550739, 23786770
FGFR2 2263 GEFITINIB CHEMBL939 CKB 26936917
FGFR2 2263 THALIDOMIDE CHEMBL468 antagonist TdgClinicalTrial, TEND, DrugBank 20616958
FGFR2 2263 Ro-4987655 CHEMBL1614766 CKB 26438159

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID