Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
CCNY rs12777960 CC adalimumab efficacy no After 20 and 30 weeks of treatment, a greater percentage of those with the CC genotype had biological response to treatment as compared to those with the AA or AC genotype. Biological response assessed using change in C-reactive protein (CRP). However, this association did not remain significant after correction for multiple testing (p=0.221) Genotype CC is associated with increased response to adalimumab in people with Crohn Disease as compared to genotypes AA + AC. 25712183 1444936520