PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
AKT1	1	SH3RF1	1	enzymatic study	Lyons TR (2007)	1
EGFR	5	APPL1	1	unspecified method	Jones RB (2006)	1
AKT2	1	PNPLA3	0	two hybrid	Wang J (2011)	1
AKT1	1	SETDB1	3	two hybrid, pull down, affinity chromatography technology	Gao H (2007), Gao H (2007), Gao H (2007)	3
CDKN1A	1	SETDB1	3	two hybrid	Vinayagam A (2011)	1
PRKDC	12	CHUK	5	enzymatic study, pull down	Liu L (1998), Liu L (1998)	2
GGA1	0	APP	1	affinity chromatography technology, pull down	Wahle T (2006), Wahle T (2006)	2
AKT2	1	SORBS2	2	two hybrid	Wang J (2011)	1
CUL1	7	RACGAP1	2	affinity chromatography technology	Bennett EJ (2010)	1
EGFR	5	AKT1	1	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
PRKDC	12	AKT2	1	enzymatic study, enzymatic study	Hresko RC (2005), Dragoi AM (2005)	2
GRK5	7	HSP90AA1	7	affinity chromatography technology	Wu Z (2012)	1
PRKDC	12	GSK3B	1	enzymatic study	Dragoi AM (2005)	1
SKI	3	AKT2	1	affinity chromatography technology	Band AM (2009)	1
AKT2	1	MTCP1	0	two hybrid	Laine J (2000)	1
UCHL1	1	AKT2	1	pull down, bioid, affinity chromatography technology	Luo Y (2018), Luo Y (2018), Luo Y (2018)	3
EGFR	5	AKT2	1	affinity chromatography technology	Tong J (2014)	1
APP	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology, pull down	Zhou F (2012), Zhou F (2012), Olah J (2011)	3
AKT2	1	GGA1	0	biochemical	Wan C (2015)	1
APP	1	SNX27	5	pull down	Ghai R (2013)	1
PRKDC	12	EIF4EBP1	1	enzymatic study	Chan DW (2000)	1
HSP90AA1	7	PRKDC	12	affinity chromatography technology	Falsone SF (2005)	1
EGFR	5	PRKCZ	5	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
AKT2	1	SNAI1	1	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Villagrasa P (2012), Villagrasa P (2012), Villagrasa P (2012), Villagrasa P (2012)	4
GRK5	7	UBE2O	5	affinity chromatography technology	Wu Z (2012)	1
VIM	0	SETDB1	3	two hybrid	Goehler H (2004)	1
AKT2	1	NAMPT	3	two hybrid	Wang J (2011)	1
EGLN1	3	HIST1H3A	3	pull down, x-ray crystallography	Musselman CA (2009), Musselman CA (2009)	2
FKBP5	0	APP	1	pull down	Olah J (2011)	1
FKBP5	0	AKT2	1	affinity chromatography technology	Luo K (2017)	1
ESR1	0	PPP2CA	7	affinity chromatography technology	Okada M (2015)	1
EGFR	5	XIAP	0	affinity chromatography technology	Yao Z (2017)	1
HSP90AA1	7	APP	1	affinity chromatography technology	Kumar P (2007)	1
AKT1	1	TTC3	1	affinity chromatography technology, enzymatic study, pull down	Suizu F (2009), Suizu F (2009), Suizu F (2009)	3
VHL	0	EGLN1	3	affinity chromatography technology, affinity chromatography technology, pull down	Foxler DE (2012), Zhang CS (2015), Zhang CS (2015)	3
VHL	0	APP	1	pull down	Olah J (2011)	1
AKT1	1	ESR1	0	enzymatic study	Campbell RA (2001)	1
CSK	3	AKT2	1	biochemical	Wan C (2015)	1
AKT1	1	UCHL1	1	affinity chromatography technology, two hybrid	Klein JB (2005), Arroyo R (2015)	2
AKT2	1	VIM	0	affinity chromatography technology, affinity chromatography technology	Zhu QS (2011), Zhu QS (2011)	2
XIAP	0	AKT1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique	Dan HC (2004), Dan HC (2004), Pramanik KC (2013), Pramanik KC (2013), Chen TC (2014)	5
WDR26	6	PIK3CB	2	affinity chromatography technology, affinity chromatography technology	Ye Y (2016), Ye Y (2016)	2
VHL	0	PPP2CA	7	affinity chromatography technology, affinity chromatography technology	Guo J (2016), Guo J (2016)	2
AKT2	1	SETDB1	3	affinity chromatography technology	Gao H (2007)	1
ESR1	0	PRKDC	12	affinity chromatography technology, affinity chromatography technology	Ju BG (2006), Tarallo R (2011)	2
AKT2	1	POLR1B	2	two hybrid	Wang J (2011)	1
SNAI1	1	HIST1H3A	3	affinity chromatography technology	Lin Y (2010)	1
AKT2	1	XIAP	0	enzymatic study	Dan HC (2004)	1
AKT1	1	GSK3B	1	pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Thimmaiah KN (2005), Drendall CI (2010), Connor MK (2005), Hunter MG (2004), Zhu QS (2011), Li L (2003), Nam SY (2010), Yang WL (2009), Zeng L (2013), Yang H (2005), Boehme KA (2008), Cross DA (1995), Hinton CV (2007), Kapoor GS (2004), Pitre A (2012), Guo J (2016)	16
AKT1	1	CSK	3	affinity chromatography technology, biochemical	Lodeiro M (2009), Wan C (2015)	2
ESR1	0	HSP90AA1	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nair SC (1996), Lee MO (2002), Fan M (2005), Tateishi Y (2004), Fiskus W (2007), Powell E (2010), Suzuki T (2011), Berry NB (2008), Sumanasekera WK (2003), Taipale M (2012), Donley C (2013), Donley C (2013), Dhamad AE (2016)	13
PSMD9	0	AKT2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
AKT2	1	GNB1	4	affinity chromatography technology	Ye Y (2016)	1
GNB1	4	WDR26	6	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sun Z (2011), Sun Z (2011), Sun Z (2011), Sun Z (2011), Sun Z (2013), Ye Y (2016)	6
RACGAP1	2	AKT2	1	affinity chromatography technology	Hein MY (2015)	1
PRKDC	12	VHL	0	genetic interference	Shen JP (2017)	1
AKT2	1	SNX27	5	two hybrid	Wang J (2011)	1
AKT1	1	SNAI1	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology	Villagrasa P (2012), Villagrasa P (2012), Villagrasa P (2012), Villagrasa P (2012)	4
TCL1A	0	AKT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, two hybrid	Laine J (2002), Laine J (2000), French SW (2002), French SW (2002), Rolland T (2014), Daakour S (2016)	6
PRKCZ	5	AKT2	1	affinity chromatography technology, affinity chromatography technology	Wang J (2008), Wang J (2008)	2
APP	1	UCHL1	1	affinity chromatography technology	Zhang M (2014)	1
EGFR	5	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Citri A (2002), Yang S (2006), Shimamura T (2005), Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014)	8
NR2F2	4	AKT2	1	affinity chromatography technology	Huttlin EL (2017)	1
PNPLA3	0	SNX27	5	two hybrid	Wang J (2011)	1
SNX27	5	APOA1	0	affinity chromatography technology	Huttlin EL (2017)	1
PPP2CA	7	CHUK	5	affinity chromatography technology	Kray AE (2005)	1
EGFR	5	SORBS2	2	protein complementation assay	Deribe YL (2009)	1
HSP90AA1	7	AKT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Haendeler J (2003), Kawauchi K (2005), Sato S (2000), Basso AD (2002), Su CH (2011), Klein JB (2005), Sun L (2012)	7
AKT1	1	AKT2	1	affinity chromatography technology	Huttlin EL (2017)	1
APP	1	UBB	4	protein complementation assay	Kajiwara Y (2010)	1
EGLN1	3	AKT2	1	affinity chromatography technology	Guo J (2016)	1
CDKN1A	1	UBB	4	affinity chromatography technology	Fogeron ML (2013)	1
CLIP3	4	AKT2	1	affinity chromatography technology, affinity chromatography technology, pull down	Ding J (2009), Ding J (2009), Ding J (2009)	3
AKT2	1	SH3RF1	1	two hybrid, pull down, enzymatic study	Figueroa C (2003), Figueroa C (2003), Lyons TR (2007)	3
SNAI1	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yook JI (2005), Zhou BP (2004), Zhou BP (2004), Wu Y (2009), Wu Y (2009), Lee JH (2017)	6
WDR26	6	AKT2	1	affinity chromatography technology, affinity chromatography technology	Ye Y (2016), Ye Y (2016)	2
AKT1	1	PIK3CB	2	biochemical	Wan C (2015)	1
CLIP3	4	AKT1	1	affinity chromatography technology, affinity chromatography technology, pull down	Ding J (2009), Ding J (2009), Ding J (2009)	3
AKT2	1	MAP3K5	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Yuan ZQ (2003), Yuan ZQ (2003), Yuan ZQ (2003)	3
CHUK	5	ESR1	0	imaging technique	Park KJ (2005)	1
AKT1	1	EIF4EBP1	1	imaging technique	Chen TC (2014)	1
AKT1	1	CDKN1A	1	pull down, enzymatic study, imaging technique, enzymatic study	Heron-Milhavet L (2006), Heron-Milhavet L (2006), Chen TC (2014), Roessig L (2001)	4
AKT1	1	TPM2	2	affinity chromatography technology	Zhu QS (2011)	1
NR2F2	4	AKT1	1	affinity chromatography technology	Huttlin EL (2017)	1
MTCP1	0	APP	1	pull down	Olah J (2011)	1
AKT1	1	RPE	3	biochemical	Wan C (2015)	1
VHL	0	AKT2	1	pull down, affinity chromatography technology	Guo J (2016), Guo J (2016)	2
AKT2	1	APP	1	pull down	Olah J (2011)	1
EGFR	5	CSK	3	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Schulze WX (2006), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
APPL1	1	UBE2O	5	two hybrid	Rolland T (2014)	1
ESR1	0	PRKCZ	5	affinity chromatography technology	Yi P (2008)	1
PDPK1	0	AKT1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Barry FA (2002), Persad S (2001), Lin K (2012), Guo J (2016), Guo J (2016)	5
GSK3B	1	HSP90AA1	7	enzymatic study	Muller P (2012)	1
VHL	0	HSP90AA1	7	affinity chromatography technology, genetic interference	Yang C (2013), Shen JP (2017)	2
HSP90AA1	7	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Huttlin EL (2015), Huttlin EL (2017)	3
GGA1	0	EIF4EBP1	1	biochemical	Wan C (2015)	1
CSK	3	PDPK1	0	two hybrid	Grossmann A (2015)	1
CUL1	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
PDPK1	0	PRKCZ	5	two hybrid, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Balendran A (2000), Hodgkinson CP (2002), Hodgkinson CP (2002), Le Good JA (1998), Le Good JA (1998), Le Good JA (1998), Balendran A (2000), Park J (1999)	8
AKT2	1	EIF4EBP1	1	biochemical	Wan C (2015)	1
EGFR	5	UCHL1	1	protein complementation assay	Deribe YL (2009)	1
CUL1	7	ESR1	0	affinity chromatography technology	Zhou W (2014)	1
HSP90AA1	7	CHUK	5	affinity chromatography technology, affinity chromatography technology	Qu X (2012), Gano JJ (2010)	2
AKT2	1	SPRR2A	2	two hybrid	Wang J (2011)	1
ESR1	0	GNB1	4	affinity chromatography technology, affinity chromatography technology	Tarallo R (2011), Han SJ (2016)	2
AKT1	1	PPP2CA	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Beaulieu JM (2008), Beaulieu JM (2008), Calvo N (2010), Calvo N (2010), Xiao L (2010), Guo J (2016), Guo J (2016), Guo J (2016)	8
GSK3B	1	AKT2	1	x-ray crystallography	Yang J (2002)	1
AP4M1	2	AKT2	1	affinity chromatography technology	Hein MY (2015)	1
PRKCZ	5	GSK3B	1	imaging technique	Chen TC (2014)	1
AKT2	1	HIST1H3A	3	enzymatic study	Villagrasa P (2012)	1
CDK3	0	FKBP5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
AKT1	1	VIM	0	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Zhu QS (2011), Zhu QS (2011), Zhu QS (2011), Zhu QS (2011)	4
PDPK1	0	APP	1	pull down	Olah J (2011)	1
AKT2	1	APOA1	0	two hybrid	Wang J (2011)	1
PDPK1	0	AKT2	1	affinity chromatography technology	Guo J (2016)	1
ABCG8	1	AKT2	1	two hybrid	Wang J (2011)	1
CUL1	7	CDKN1A	1	affinity chromatography technology	Yu ZK (1998)	1
AKT1	1	EGLN1	3	affinity chromatography technology, affinity chromatography technology	Guo J (2016), Guo J (2016)	2
GSK3B	1	XIAP	0	affinity chromatography technology	Sun M (2009)	1
PRKCZ	5	HSP90AA1	7	two hybrid, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Taipale M (2012), Taipale M (2012)	3
MTCP1	0	AKT1	1	affinity chromatography technology, affinity chromatography technology	Laine J (2002), Laine J (2000)	2
EGFR	5	APP	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
CUL1	7	CDK3	0	affinity chromatography technology	Bennett EJ (2010)	1
FKBP5	0	CHUK	5	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CUL1	7	PPP2CA	7	affinity chromatography technology	Bennett EJ (2010)	1
HSP90AA1	7	SETDB1	3	affinity chromatography technology	Taipale M (2012)	1
AKT2	1	PPP2CA	7	affinity chromatography technology, affinity chromatography technology	Guo J (2016), Guo J (2016)	2
VHL	0	SETDB1	3	affinity chromatography technology	Huttlin EL (2017)	1
AKT2	1	STEAP4	0	two hybrid	Wang J (2011)	1
AKT2	1	TTC3	1	affinity chromatography technology	Suizu F (2009)	1
MAP3K5	1	APP	1	imaging technique	Chen TC (2014)	1
CUL1	7	AKT2	1	affinity chromatography technology	Reitsma JM (2017)	1
PRKDC	12	HIST1H3A	3	imaging technique	Olsen BB (2012)	1
EGLN1	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Song D (2013), Song D (2013), Song D (2013), Song D (2014), Song D (2014)	5
PRKDC	12	AKT1	1	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, genetic interference	Feng J (2004), Feng J (2004), Feng J (2004), Dragoi AM (2005), Dragoi AM (2005), Dragoi AM (2005), Shen JP (2017)	7
AKT2	1	TCL1B	1	two hybrid	Laine J (2000)	1
GRK5	7	AKT2	1	affinity chromatography technology	Wu Z (2012)	1
EGFR	5	APOB	8	affinity chromatography technology, affinity chromatography technology	Li J (2013), Yao Z (2017)	2
PRKDC	12	PPP2CA	7	affinity chromatography technology	Douglas P (2010)	1
TMEM17	0	APPL1	1	bioid	Gupta GD (2015)	1
PLEKHO1	1	AKT2	1	pull down, affinity chromatography technology	Tokuda E (2007), Tokuda E (2007)	2
APPL1	1	PRKCZ	5	imaging technique, affinity chromatography technology	Song J (2016), Song J (2016)	2
SKI	3	WDR26	6	affinity chromatography technology	Rashidian J (2015)	1
GSK3B	1	VIM	0	two hybrid	Vinayagam A (2011)	1
APPL1	1	AKT1	1	affinity chromatography technology, two hybrid, imaging technique	Yang L (2003), Grossmann A (2015), Chen TC (2014)	3
AKT2	1	APOB	8	two hybrid	Wang J (2011)	1
AKT1	1	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, unspecified method	Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016)	5
SKI	3	PRKDC	12	affinity chromatography technology	Rashidian J (2015)	1
CSK	3	PSMD9	0	biochemical	Wan C (2015)	1
EGFR	5	PIK3CB	2	affinity chromatography technology	Foerster S (2013)	1
AKT1	1	CHUK	5	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Ozes ON (1999), Ozes ON (1999), Romashkova JA (1999), Lu Y (2005), Chen TC (2014), Takada Y (2005), Koul D (2001)	7
CDKN1A	1	APP	1	pull down	Olah J (2011)	1
GSK3B	1	EIF4EBP1	1	two hybrid	Vinayagam A (2011)	1
AKT1	1	APP	1	pull down	Olah J (2011)	1
CDK3	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Huttlin EL (2017)	4
AKT2	1	USP9Y	0	affinity chromatography technology	Huttlin EL (2017)	1
GRK5	7	PRKDC	12	affinity chromatography technology	Wu Z (2012)	1
TMEM17	0	AKT2	1	bioid	Gupta GD (2015)	1
AKT2	1	PIK3CB	2	biochemical	Wan C (2015)	1
AKT1	1	GNB1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Klein JB (2005), Xiong Y (2009), Xiong Y (2009)	3
CUL1	7	AKT1	1	affinity chromatography technology	Reitsma JM (2017)	1
EGFR	5	ESR1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hitosugi T (2007), Hitosugi T (2007), Yao Z (2017)	3
SKI	3	AKT1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Band AM (2009), Band AM (2009), Band AM (2009)	3
SKI	3	ESR1	0	affinity chromatography technology	Band AM (2011)	1
AKT2	1	CCL14	1	two hybrid	Wang J (2011)	1
TCL1B	1	APP	1	pull down	Olah J (2011)	1
AKT2	1	ESR1	0	enzymatic study, affinity chromatography technology	Sun M (2001), Sun M (2001)	2
PLEKHO1	1	AKT1	1	pull down, affinity chromatography technology	Tokuda E (2007), Tokuda E (2007)	2
FKBP5	0	AKT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mistafa O (2010), Luo K (2017), Luo K (2017)	3
CHUK	5	CUL1	7	affinity chromatography technology	Kumar A (2007)	1
PIK3CB	2	GNB1	4	affinity chromatography technology	Ye Y (2016)	1
HSP90AA1	7	AKT2	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Taipale M (2012)	2
UBE2O	5	WDR26	6	biochemical	Havugimana PC (2012)	1
UCHL1	1	HSP90AA1	7	affinity chromatography technology, pull down	Kabuta T (2008), Kabuta T (2008)	2
TCL1A	0	AKT2	1	affinity chromatography technology, two hybrid, affinity chromatography technology	Laine J (2002), Laine J (2000), Laine J (2000)	3
FSHR	2	APPL1	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Cohen BD (2004), Nechamen CA (2004), Nechamen CA (2004), Nechamen CA (2004)	4
AKT2	1	UBB	4	affinity chromatography technology	Huttlin EL (2017)	1
AKT2	1	PIK3CD	4	biochemical	Wan C (2015)	1
AKT2	1	CHUK	5	affinity chromatography technology, enzymatic study	Yuan ZQ (2002), Yuan ZQ (2002)	2
ESR1	0	FKBP5	0	pull down, affinity chromatography technology	Nair SC (1996), Dhamad AE (2016)	2
AKT2	1	RPE	3	biochemical	Wan C (2015)	1
EGFR	5	WDR26	6	affinity chromatography technology	Foerster S (2013)	1
AKT2	1	POFUT1	2	two hybrid	Wang J (2011)	1
AKT2	1	NSMCE4A	0	affinity chromatography technology	Huttlin EL (2017)	1
AKT2	1	UBE2O	5	affinity chromatography technology	Huttlin EL (2017)	1
APOA1	0	APP	1	pull down	Olah J (2011)	1
FKBP5	0	HSP90AA1	7	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Nair SC (1997), Nair SC (1997), Li J (2011), Schuelke JP (2010), Gano JJ (2010), Skarra DV (2011), Horibe T (2011), Kristensen AR (2012), Taipale M (2014), Taipale M (2014), Graumann K (2000), Ni L (2010), Luo K (2017)	13
AKT2	1	TMED2	0	two hybrid	Wang J (2011)	1
AKT1	1	TCL1B	1	affinity chromatography technology	Laine J (2000)	1
FKBP5	0	EGLN1	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
AKT2	1	TPM2	2	affinity chromatography technology	Huttlin EL (2017)	1
AKT2	1	FAT3	15	affinity chromatography technology	Huttlin EL (2017)	1
CDKN1A	1	VIM	0	two hybrid	Vinayagam A (2011)	1
HSP90AA1	7	MAP3K5	1	affinity chromatography technology	Taipale M (2012)	1
CDK3	0	APP	1	pull down	Olah J (2011)	1
FSHR	2	AKT2	1	affinity chromatography technology	Nechamen CA (2004)	1
SETDB1	3	HIST1H3A	3	enzymatic study, pull down	Vandel L (2001), Binda O (2011)	2
HSP90AA1	7	CDKN1A	1	affinity chromatography technology	Jascur T (2005)	1
CDKN1A	1	MAP3K5	1	affinity chromatography technology	Huang S (2003)	1
CDK3	0	AKT2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGFR	5	PRKDC	12	affinity chromatography technology	Foerster S (2013)	1
VHL	0	PRKCZ	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Okuda H (1999), Okuda H (1999), Schermer B (2006)	3
AKT1	1	MAP3K5	1	affinity chromatography technology, enzymatic study	Kim AH (2001), Kim AH (2001)	2
CHUK	5	PSMD9	0	affinity chromatography technology, affinity chromatography technology, genetic interference	Sahu I (2014), Sahu I (2014), Sahu I (2014)	3
PRKCZ	5	AKT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Doornbos RP (1999), Wang J (2008), Wang J (2008), Joshi J (2008), Joshi J (2008)	5
ESR1	0	CDKN1A	1	pull down, pull down, pull down, affinity chromatography technology	Fritah A (2005), Maynadier M (2008), Maynadier M (2008), Kinyamu HK (2003)	4
CDKN1A	1	AKT2	1	affinity chromatography technology, pull down	Heron-Milhavet L (2006), Heron-Milhavet L (2006)	2
AKT2	1	APPL1	1	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Mitsuuchi Y (1999), Mitsuuchi Y (1999), Mitsuuchi Y (1999), Nechamen CA (2007)	4
APOA1	0	APOB	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rutledge AC (2009), Rutledge AC (2009), Zhang J (2017), Zhang J (2017)	4
TMEM17	0	GGA1	0	bioid	Gupta GD (2015)	1
VIM	0	APP	1	pull down	Olah J (2011)	1
CUL1	7	VIM	0	affinity chromatography technology	Bennett EJ (2010)	1