Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
ERCC3	rs3738948	AG + GG	Platinum compounds	efficacy	yes	Additive model (100% of patients with GG achieved response, 89.3% of patients with AG genotype, 68.3% of patients with AA genotype). Platinum-based doublets consisting of cisplatin or carboplatin plus gemcitabine, vinorelbine, taxane or pemetrexed. Response defined as complete or partial response; non-response defined as stable disease or progression disease.	Genotypes AG + GG is associated with increased response to Platinum compounds in people with Carcinoma, Non-Small-Cell Lung as compared to genotype AA.	25069034	1296667136