PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
ERBB2	6	JAK2	1	affinity chromatography technology	Ren Z (2002)	1
CBL	7	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Valiya Veettil M (2011), Brehme M (2009)	2
SHC1	0	HSP90AA1	7	affinity chromatography technology	Brehme M (2009)	1
JAK2	1	EGFR	5	affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study	Olayioye MA (1999), Olayioye MA (1999), Jones RB (2006), He K (2013)	4
HSP90AB1	2	TUBA1A	13	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CD44	1	SRC	2	affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Bourguignon LY (2001), Bourguignon LY (2001), Su YJ (2011), Zhu D (1998)	4
HSPA8	4	TUBA1A	13	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CBL	7	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tanaka Y (2008), Tanaka Y (2008), Hoff H (2007), Chernock RD (2001), Chernock RD (2001)	5
GRB2	2	AP2M1	5	affinity chromatography technology	Blagoev B (2003)	1
CTNNB1	30	HDAC6	0	affinity chromatography technology	Li Y (2008)	1
VAV2	6	CBLB	3	two hybrid	Bustelo XR (1997)	1
PLCG1	6	SOS2	3	two hybrid, affinity chromatography technology	Scholler JK (2000), Scholler JK (2000)	2
GRB2	2	HSP90AA1	7	affinity chromatography technology	Brehme M (2009)	1
EGFR	5	APBB2	2	unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
HSPA1A	0	AR	3	affinity chromatography technology, affinity chromatography technology	Veldscholte J (1992), Ni L (2010)	2
CBLB	3	VAV1	2	affinity chromatography technology, two hybrid, pull down, far western blotting, affinity chromatography technology	Sattler M (2002), Bustelo XR (1997), Bustelo XR (1997), Bustelo XR (1997), Bustelo XR (1997)	5
ERBB3	3	CDC37	0	affinity chromatography technology	Li J (2013)	1
SRC	2	EPS8	1	enzymatic study, pull down	Maa MC (1999), Maa MC (1999)	2
HSP90AB1	2	SRC	2	affinity chromatography technology	Karras GI (2017)	1
ERBB2	6	CRK	0	unspecified method	Jones RB (2006)	1
EGFR	5	LYN	2	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Wu SL (2006), Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
PML	7	STAT1	1	affinity chromatography technology, affinity chromatography technology	Chen Y (2015), Kim YE (2015)	2
SHC1	0	AP2M1	5	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
CD44	1	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsatas D (2002), Wakahara K (2005), Wakahara K (2005), Perez A (2013)	4
ERBB2	6	PTPN11	20	affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Jones RB (2006), Yao Z (2017), Vogel W (1996)	5
PIK3R2	3	CRKL	1	far western blotting, affinity chromatography technology, affinity chromatography technology	Sattler M (1997), Sattler M (1997), Martelli MP (2001)	3
PLCG1	6	RET	3	pull down, imaging technique	Borrello MG (1996), Chen TC (2014)	2
NCK2	2	BAIAP2	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PTPN11	20	CAV1	0	affinity chromatography technology	Caselli A (2002)	1
EGFR	5	HSPA5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavictoire SJ (2003), Foerster S (2013), Li J (2013), Yao Z (2017)	4
CBL	7	NCK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Erdreich-Epstein A (1999), Miyoshi-Akiyama T (2001), Izadi KD (1998), Izadi KD (1998), Wunderlich L (1999), Shishido T (2000), Okabe S (2006), Adler CE (2000), Adler CE (2000), Buvall L (2013), Buvall L (2013), Buvall L (2013), Buvall L (2013)	13
SRC	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Burnham MR (1999), Song JJ (2010), Liu W (2010), Chen TC (2014)	4
EGFR	5	CRKL	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2008), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
PTPN12	2	SHC1	0	two hybrid, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Habib T (1994), Charest A (1996), Charest A (1996), Habib T (1994), Habib T (1994), Brehme M (2009), Li J (2013), St-Denis N (2016), St-Denis N (2016), Huttlin EL (2017)	10
CDK1	0	HSP90AA1	7	affinity chromatography technology	Garcia-Morales P (2007)	1
EGFR	5	AP2M1	5	protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Deribe YL (2009), Foerster S (2013), Li J (2013), Tong J (2014), Li J (2013)	5
TNK2	7	LYN	2	pull down, affinity chromatography technology	Chan W (2011), Chan W (2011)	2
CTNNB1	30	YWHAZ	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen CH (2012), Chen CH (2012), Tian Q (2004), Tian Q (2004), Tian Q (2004), Fang D (2007)	6
CTNNB1	30	SRC	2	affinity chromatography technology	Xi Y (2013)	1
ERBB3	3	PIK3R2	3	affinity chromatography technology, unspecified method, affinity chromatography technology	Schulze WX (2006), Jones RB (2006), Li J (2013)	3
ERCC1	1	EGFR	5	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Liccardi G (2014), Liccardi G (2014), Liccardi G (2014), Liccardi G (2014)	4
HSPA1A	0	HSPA8	4	biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012)	2
EPS15	1	CRKL	1	affinity chromatography technology	Brehme M (2009)	1
PTPN1	2	GRB2	2	pull down, pull down, affinity chromatography technology	Goldstein BJ (2000), Liu F (1996), Li X (2016)	3
EGFR	5	CAV2	0	affinity chromatography technology, two hybrid, protein complementation assay, pull down	Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Abulrob A (2004)	4
GRB2	2	VAV2	6	affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Bourguignon LY (2001)	2
EGFR	5	GAPDH	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Foerster S (2013), Wu SL (2006), Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014)	5
TNK2	7	CSK	3	affinity chromatography technology	Mahendrarajah N (2017)	1
CDH1	4	ERBB3	3	bioid	Guo Z (2014)	1
HSP90AB1	2	HSPA4	3	biochemical, affinity chromatography technology	Wan C (2015), Reidy M (2018)	2
CDH1	4	CRK	0	bioid	Guo Z (2014)	1
EPS15	1	GRB2	2	far western blotting, affinity chromatography technology, affinity chromatography technology, pull down	Schumacher C (1995), Parachoniak CA (2009), Parachoniak CA (2009), Parachoniak CA (2009)	4
CRK	0	GAB1	3	affinity chromatography technology	Brehme M (2009)	1
CBL	7	PIK3R2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Lin H (2001), Hartley D (1995), Feshchenko EA (2004), Alcazar I (2009), Brehme M (2009), Brehme M (2009), Grossmann A (2015)	7
CTTN	1	HDAC6	0	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study	Zhang X (2007), Zhang X (2007), Zhang X (2007), Kaluza D (2011), Kaluza D (2011)	5
SRC	2	CDC25A	2	enzymatic study	Liang J (2016)	1
EPS8	1	GRB2	2	two hybrid	Rolland T (2014)	1
ERBB2	6	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Scaltriti M (2009), Graus-Porta D (1997), Le XF (2005), Chen TC (2014), Ritch PS (2005)	5
CALM1	0	AR	3	affinity chromatography technology, pull down, imaging technique	Cifuentes E (2004), Cifuentes E (2004), Cifuentes E (2004)	3
ERRFI1	1	TUBA1A	13	affinity chromatography technology	Li J (2013)	1
LYN	2	PTPN6	0	pull down	Yoshida K (1999)	1
CAV2	0	NCK1	0	pull down	Lee H (2002)	1
CBL	7	HSPA4	3	affinity chromatography technology	Valiya Veettil M (2011)	1
HSPA5	0	HSPA4	3	biochemical	Havugimana PC (2012)	1
HSP90AA1	7	ERBB2	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu W (2001), Jeong JH (2008), Mollapour M (2010), Citri A (2002), Jung Y (2007), Suzuki T (2011), Tsutsumi S (2012), Taipale M (2012), Bali P (2005), Woodford MR (2016), Yan YY (2011), Yan YY (2011)	12
PTPN11	20	SOCS3	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Lehmann U (2003), Lehmann U (2003), Schmitz J (2000), Orr SJ (2007)	4
PLCG2	11	PRKCA	7	affinity chromatography technology	Wang J (2006)	1
EGFR	5	SLC3A2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wu SL (2006), Wu SL (2006), Tong J (2014), Li J (2013)	4
ERBB2	6	STAT3	0	affinity chromatography technology, unspecified method	Ren Z (2002), Jones RB (2006)	2
NCK2	2	ERBB2	6	unspecified method	Jones RB (2006)	1
MUC1	0	EGFR	5	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique, two hybrid, protein complementation assay, affinity chromatography technology, enzymatic study	Schroeder JA (2001), Li Y (2001), Li Y (2001), Pochampalli MR (2007), Merlin J (2011), Merlin J (2011), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Schroeder JA (2001)	10
PTPN6	0	PLCG2	11	affinity chromatography technology, fluorescent resonance energy transfe	Matalon O (2016), Matalon O (2016)	2
PIK3R2	3	SHC1	0	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009)	2
TUBA1A	13	YWHAZ	1	genetic interference	Srivas R (2016)	1
NCK2	2	EGFR	5	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Chen M (1998), Braverman LE (1999), Tu Y (1998), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	6
JAK2	1	SOCS3	0	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Sasaki A (2000), Sasaki A (2000), Sasaki A (1999), Sasaki A (1999), Sasaki A (1999), Masuhara M (1997), Masuhara M (1997), Monni R (2001), Haan S (2009), Babon JJ (2012), Calegari VC (2005), Calegari VC (2005), Varghese LN (2014), Kershaw NJ (2014)	14
LYN	2	CDK1	0	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Kharbanda S (1994), Kharbanda S (1994), Kharbanda S (1994), Pathan NI (1996)	4
STUB1	4	TRAF2	1	affinity chromatography technology	Jang KW (2011)	1
HSP90AA1	7	RET	3	affinity chromatography technology	Taipale M (2012)	1
HSP90AA1	7	LYN	2	affinity chromatography technology	Taipale M (2012)	1
CSK	3	SHC1	0	pull down, affinity chromatography technology	Sato K (2002), Brehme M (2009)	2
HSP90AB1	2	GAPDH	0	affinity chromatography technology, biochemical	Falsone SF (2005), Wan C (2015)	2
SH3KBP1	1	CRK	0	affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000)	2
STAT5A	4	JAK2	1	affinity chromatography technology, two hybrid, pull down, enzymatic study	Barahmand-Pour F (1998), Fujitani Y (1997), Fujitani Y (1997), Gouilleux F (1994)	4
SRC	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Olayioye MA (1999), Keely SJ (2000), Sato K (2000), Lee CW (2007), Jaganathan S (2011), Jaganathan S (2011), Lee IT (2010), Hitosugi T (2007), Chang CC (2012), Chang CC (2012), Tung WH (2011), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Yao Z (2017)	15
EGFR	5	PTPN6	0	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid	Tomic S (1995), Keilhack H (1998), Keilhack H (1998), Yao Z (2017)	4
VAV1	2	APBB2	2	affinity chromatography technology	Huttlin EL (2017)	1
CBLB	3	PLCG2	11	affinity chromatography technology	Yasuda T (2002)	1
HDAC6	0	PTPN11	20	affinity chromatography technology	M L (2016)	1
SOS2	3	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Qian X (2000), Tong J (2009), Tong J (2008), Foerster S (2013), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014)	7
GRB2	2	PIK3R1	6	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Saleem A (1995), Saleem A (1995), Wang J (1995), Wang J (1995), Wang J (1995), Bandyopadhyay S (2010), Takahashi Y (1999), Gelkop S (2001), Jain SK (1997), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Cerboni C (1998), Bisson N (2011), Bisson N (2011), Weinger JG (2008), Weinger JG (2008), Weinger JG (2008)	18
EGFR	5	AP2A1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Foerster S (2013), Tong J (2014), Li J (2013)	4
YWHAZ	1	PRKCA	7	affinity chromatography technology	Gannon-Murakami L (2002)	1
TNK2	7	HSP90AB1	2	affinity chromatography technology	Mahendrarajah N (2017)	1
GAPDH	0	AR	3	two hybrid, pull down	Koshy B (1996), Koshy B (1996)	2
GAB1	3	PTPN11	20	affinity chromatography technology, two hybrid, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Saito Y (2002), Rocchi S (1998), Ingham RJ (1998), Ingham RJ (1998), van den Akker E (2004), Kapoor GS (2004), Kapoor GS (2004), Kapoor GS (2010), Fan YX (2013)	9
CRK	0	PIK3C2B	5	affinity chromatography technology	Brehme M (2009)	1
CRK	0	RET	3	pull down, imaging technique	Bocciardi R (1997), Chen TC (2014)	2
EGFR	5	GSTP1	0	enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Okamura T (2015), Okamura T (2009), Okamura T (2009), Okamura T (2009)	4
HSPA5	0	SFN	1	biochemical	Wan C (2015)	1
CRK	0	SOS1	5	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Okada S (1996), Okada S (1996), Okada S (1996), Ingham RJ (1996), Brehme M (2009), Chen TC (2014)	6
SRC	2	RET	3	affinity chromatography technology	Melillo RM (1999)	1
CALM1	0	HSP90AA1	7	pull down	Ning YM (1995)	1
STUB1	4	SRC	2	pull down, affinity chromatography technology, imaging technique, enzymatic study	Yang M (2011), Yang M (2011), Yang M (2011), Yang M (2011)	4
EGFR	5	BAIAP2	6	two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013)	4
HSP90AA1	7	STAT3	0	affinity chromatography technology	Sato N (2003)	1
EGFR	5	HSPA4	3	protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Deribe YL (2009), Deribe YL (2009), Citri A (2002), Tong J (2008), Kotlyar M (2015), Petschnigg J (2014)	6
ERBB3	3	SHC1	0	affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Jones RB (2006), Li J (2013), Hellyer NJ (2001)	5
NCK2	2	TNK2	7	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
STAT3	0	PIK3R3	0	two hybrid	Grossmann A (2015)	1
CDH1	4	CRKL	1	bioid	Guo Z (2014)	1
CBLC	1	EGFR	5	affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, x-ray crystallography	Kim M (1999), Keane MM (1999), Keane MM (1999), Takeshita K (2012), Takeshita K (2012), Takeshita K (2012)	6
SFN	1	PIK3C2B	5	affinity chromatography technology	Benzinger A (2005)	1
CDH1	4	USP8	7	bioid	Guo Z (2014)	1
ZAP70	5	TUBA1A	13	affinity chromatography technology, affinity chromatography technology, pull down	Huby RD (1995), Huby RD (1995), Huby RD (1995)	3
CDH1	4	JUP	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Kinch MS (1995), Hazan RB (1998), Shibata T (1994), Hinck L (1994), Knudsen KA (1992), Geng F (2012), Guo Z (2014)	7
CDH1	4	HSP90AB1	2	bioid	Guo Z (2014)	1
EGFR	5	PIK3R2	3	affinity chromatography technology, unspecified method, affinity chromatography technology, two hybrid, pull down, protein complementation assay	Tong J (2009), Jones RB (2006), Foerster S (2013), Kotlyar M (2015), Gout I (1992), Petschnigg J (2014)	6
CDC25A	2	SFN	1	affinity chromatography technology	Li X (2016)	1
SH3GL2	1	CBL	7	affinity chromatography technology	Soubeyran P (2002)	1
STAT3	0	CBL	7	two hybrid	Grossmann A (2015)	1
USP8	7	GRB2	2	pull down	Kato M (2000)	1
TRAF2	1	CAV1	0	affinity chromatography technology, affinity chromatography technology	Feng X (2001), Cao H (2002)	2
PTPN6	0	PIK3R1	6	two hybrid	Sathish JG (2001)	1
CRK	0	HSP90AB1	2	affinity chromatography technology	Brehme M (2009)	1
CDH1	4	BAIAP2	6	bioid	Guo Z (2014)	1
EGFR	5	USP8	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Mizuno E (2005), Meijer IM (2013), Meijer IM (2013), Ali N (2013), Reincke M (2015), Reincke M (2015), Jeong CH (2015)	7
CRK	0	HSPA8	4	affinity chromatography technology	Brehme M (2009)	1
HDAC6	0	STUB1	4	affinity chromatography technology	Cook C (2012)	1
EGFR	5	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ettenberg SA (1999), Tvorogov D (2002), Pennock S (2008), Umebayashi K (2008), Ng C (2008), Ng C (2008), Povlsen GK (2008), Khan EM (2008), Su X (2007), Shtiegman K (2007), Han W (2006), Visser GD (2005), Tsacoumangos A (2005), Prasad NK (2005), Gur G (2004), Kowanetz K (2004), Feshchenko EA (2004), Wu WJ (2003), Schmidt MH (2003), Bao J (2003), Rubin C (2003), Waterman H (1999), Bonaccorsi L (2007), Dey N (2011), Miraoui H (2010), Guo HB (2009), Tong J (2009), Tong J (2009), Sun Q (2010), Sanada F (2009), Rafiq K (2011), Ravid T (2004), Ravid T (2004), Duan L (2011), Duan L (2011), Haglund K (2005), Oksvold MP (2003), Oksvold MP (2003), Gui A (2012), Yang S (2006), de Melker AA (2004), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Raguz J (2007), de Melker AA (2004), Thien CB (2001), Kassenbrock CK (2004), Tarcic G (2009), Schroeder B (2012), Adachi S (2009), Shen F (2007), Mitsushima M (2006), Choi JH (2003), Burke P (2001), Tanaka S (1995), Meisner H (1995), Meisner H (1995), Kumar EA (2012), Tong J (2008), Dou H (2012), Levkowitz G (1999), Levkowitz G (1999), Bode AM (2009), Thomas C (2012), Meijer IM (2013), Chang CC (2012), Chang CC (2012), Smith CJ (2013), Gan Y (2010), Scott RP (2005), Fukazawa T (1996), Fukazawa T (1996), Fukazawa T (1996), Wang L (2013), Hong SY (2013), Sigismund S (2013), Sigismund S (2013), Sigismund S (2013), Meisner H (1997), Odintsova E (2013), Kondratov KA (2010), He Z (2014), Tong J (2014), Balaji K (2012), Kiuchi T (2014), Zhang B (2005), Waterman H (1999), Ha Thi HT (2015), Yao S (2015), Kortuem F (2015), Igloi Z (2015), Song F (2016), Song F (2016), Lin TY (2017), Conte A (2017)	96
PTPN12	2	ANKS1A	3	biochemical	Kristensen AR (2012)	1
CDH1	4	GAB1	3	bioid	Guo Z (2014)	1
CBL	7	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017)	83
SRC	2	PIK3R3	0	two hybrid	Grossmann A (2015)	1
CBL	7	HSPA8	4	affinity chromatography technology	Brehme M (2009)	1
HGS	5	HSPA8	4	pull down	Pridgeon JW (2009)	1
STAT3	0	PML	7	affinity chromatography technology, pull down	Kawasaki A (2003), Kawasaki A (2003)	2
PLCG2	11	VAV1	2	affinity chromatography technology	Guo B (2000)	1
CAV1	0	HDAC6	0	affinity chromatography technology	Li Y (2008)	1
AP2M1	5	AP2A1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Brehme M (2009), Li J (2013), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	5
HSPA5	0	STUB1	4	affinity chromatography technology	Hein MY (2015)	1
SRC	2	PDCD6IP	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Schmidt MH (2005), Schmidt MH (2005), Zhou X (2010), Zhou X (2010)	4
CALM1	0	SH3GL2	1	affinity chromatography technology	Myers MD (2016)	1
ERBB3	3	VAV2	6	unspecified method	Jones RB (2006)	1
PTPN11	20	STAT5A	4	pull down, enzymatic study, affinity chromatography technology	Yu CL (2000), Yu CL (2000), Chughtai N (2002)	3
MUC1	0	ERBB2	6	affinity chromatography technology, imaging technique, affinity chromatography technology	Li Y (2003), Li Y (2003), Schroeder JA (2001)	3
EGFR	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique	Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014)	6
MUC1	0	JUP	7	affinity chromatography technology, imaging technique	Li Y (2003), Li Y (2003)	2
PLCG1	6	SOS1	5	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim MJ (2000), Kim MJ (2000), Kim MJ (2000), Kim MJ (2000), Scholler JK (2000)	5
CAV1	0	PLCG1	6	affinity chromatography technology	Boettcher JP (2010)	1
PLCG2	11	PLCG1	6	imaging technique	Chen TC (2014)	1
RET	3	CBLC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsui CC (2008), Tsui CC (2008), Kales SC (2014), Kales SC (2014)	4
CBL	7	RET	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Carniti C (2003), Carniti C (2003), Scott RP (2005)	3
PIK3R2	3	PTPN11	20	affinity chromatography technology	Brehme M (2009)	1
CBL	7	PLCG1	6	far western blotting, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique	Tvorogov D (2002), Tvorogov D (2002), Tvorogov D (2002), Graham LJ (1998), Singh AJ (2007), Rellahan BL (2003), Rellahan BL (2003), Okabe S (2006), Choi JH (2003), Choi JH (2003), Braiman A (2006), Braiman A (2006), Braiman A (2006), Chen TC (2014)	14
CBLB	3	PTPN11	20	affinity chromatography technology	Hoff H (2007)	1
SOS1	5	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hadari YR (1998), Chin H (1997), Kapoor GS (2010), Yu WM (2006)	4
UBASH3B	4	CSK	3	affinity chromatography technology	Brehme M (2009)	1
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
JAK2	1	HSP90AB1	2	affinity chromatography technology	Cheng MB (2010)	1
CRKL	1	SOS1	5	affinity chromatography technology	Hein MY (2015)	1
PIK3R1	6	JAK2	1	pull down, genetic interference	Ren SY (2005), Shen JP (2017)	2
SRC	2	PTPN1	2	enzymatic study, affinity chromatography technology	Jung EJ (1998), Ragab A (2003)	2
CDC25A	2	EGFR	5	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Wang Z (2002), Wang Z (2002), Wang Z (2002), Wang Z (2002)	4
HSP90AA1	7	BLK	4	affinity chromatography technology	Taipale M (2012)	1
SHC1	0	HSPA1A	0	affinity chromatography technology	Li J (2013)	1
PTPN11	20	STAT1	1	two hybrid	Daakour S (2016)	1
VAV1	2	PTPN6	0	pull down	Kon-Kozlowski M (1996)	1
PLCG1	6	PTPN6	0	affinity chromatography technology, affinity chromatography technology	Matalon O (2016), Matalon O (2016)	2
HSP90AA1	7	HSPA4	3	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Kim TS (2006), Hidalgo-de-Quintana J (2008), Skarra DV (2011), Wan C (2015)	4
PLCG1	6	ERBB2	6	affinity chromatography technology, biochemical, unspecified method	Peles E (1991), Arteaga CL (1991), Jones RB (2006)	3
EGFR	5	YWHAZ	1	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2009), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
CD44	1	STAT3	0	affinity chromatography technology	Su YJ (2011)	1
SOS1	5	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000)	2
ERBB2	6	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, far western blotting	Schroeder JA (2002), Bonvini P (2001), Schroeder JA (2002), Schroeder JA (2002), Kanai Y (1995), Kanai Y (1995)	6
GRB2	2	SH3KBP1	1	pull down, pull down	Gout I (2000), Borinstein SC (2000)	2
CDH1	4	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Genda T (2000), Swaminathan G (2011), Shen Y (2008), Guo Z (2014)	4
CRKL	1	GAB1	3	affinity chromatography technology, affinity chromatography technology, imaging technique	Sakkab D (2000), Sakkab D (2000), Chen TC (2014)	3
CTNNB1	30	CTNND1	4	affinity chromatography technology, affinity chromatography technology	Hazan RB (1998), Kucerova D (2001)	2
EGFR	5	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Citri A (2002), Yang S (2006), Shimamura T (2005), Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014)	8
EGFR	5	HSPA1A	0	protein complementation assay, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Deribe YL (2009), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013)	5
STAT3	0	PIK3R1	6	two hybrid	Grossmann A (2015)	1
EGFR	5	ERRFI1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tong J (2009), Pao-Chun L (2009), Tong J (2008), Foerster S (2013), Li J (2013), Tong J (2014), Li J (2013), Park E (2015), Park E (2015), Park E (2015), Park E (2015), Yao Z (2017)	12
SFN	1	CDK1	0	affinity chromatography technology	Chan TA (1999)	1
EGFR	5	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Soubeyran P (2002), Szymkiewicz I (2002), Schmidt MH (2004), Schmidt MH (2003), Ronning SB (2011), Ronning SB (2011), Yang S (2006), Schmidt MH (2003)	8
ERRFI1	1	HSPA8	4	affinity chromatography technology	Li J (2013)	1
HSPA5	0	HSP90AB1	2	biochemical	Havugimana PC (2012)	1
JAK2	1	HSPA8	4	affinity chromatography technology	Sarkar S (2001)	1
SH2D3A	3	EGFR	5	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Lu Y (1999), Lu Y (1999), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
ERBB3	3	CRK	0	unspecified method	Jones RB (2006)	1
PTPN6	0	PTPN12	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Li X (2016)	2
EGFR	5	COX2	0	affinity chromatography technology, unspecified method, affinity chromatography technology, biochemical	Tong J (2014), Boerner JL (2004), Boerner JL (2004), Boerner JL (2004)	4
JAK2	1	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Chauhan D (1995), Chauhan D (1995), Giorgetti-Peraldi S (1995), Brizzi MF (1996)	4
CDC37	0	SRC	2	pull down	Rao J (2001)	1
GRB2	2	GAPDH	0	affinity chromatography technology	Brehme M (2009)	1
SHC1	0	HSP90AB1	2	affinity chromatography technology	Brehme M (2009)	1
CTNNB1	30	JUP	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Hazan RB (1998), Kucerova D (2001), Hein MY (2015), Chen TC (2014)	4
YWHAZ	1	ERRFI1	1	affinity chromatography technology, affinity chromatography technology	Benzinger A (2005), Li J (2013)	2
EPS15	1	AP2M1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009), Li J (2013), Huttlin EL (2015), Huttlin EL (2017)	5
MUC1	0	GRB2	2	pull down, affinity chromatography technology, two hybrid	Pandey P (1995), Pandey P (1995), Bandyopadhyay S (2010)	3
CRK	0	SFN	1	affinity chromatography technology	Brehme M (2009)	1
ZAP70	5	HSPA4	3	affinity chromatography technology	Loewenberg M (2006)	1
YWHAZ	1	SFN	1	biochemical, affinity chromatography technology, affinity chromatography technology	Kristensen AR (2012), Huttlin EL (2015), Huttlin EL (2017)	3
CAV1	0	VAV2	6	affinity chromatography technology, affinity chromatography technology, pull down	Boettcher JP (2010), Boettcher JP (2010), Boettcher JP (2010)	3
PTPN11	20	CTNNB1	30	affinity chromatography technology	Ukropec JA (2000)	1
HSP90AA1	7	TUBA1A	13	affinity chromatography technology, affinity chromatography technology	Hu Y (2003), Skarra DV (2011)	2
LYN	2	SH3KBP1	1	affinity chromatography technology	Narita T (2005)	1
SH3KBP1	1	CBLB	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down	Szymkiewicz I (2002), Szymkiewicz I (2002), Szymkiewicz I (2002), Havrylov S (2009), Moncalian G (2006), Jozic D (2005), Jozic D (2005), Kowanetz K (2003), Ceregido MA (2013), Ceregido MA (2013), Ceregido MA (2013)	11
CBLC	1	CRK	0	pull down, two hybrid	Keane MM (1999), Grossmann A (2015)	2
STAT1	1	CTTN	1	biochemical	Kristensen AR (2012)	1
SHC1	0	TUBA1A	13	affinity chromatography technology	Brehme M (2009)	1
CRK	0	PIK3R3	0	affinity chromatography technology, two hybrid	Brehme M (2009), Grossmann A (2015)	2
CDH1	4	PTPN1	2	bioid	Guo Z (2014)	1
GRB2	2	YWHAZ	1	affinity chromatography technology	Bisson N (2011)	1
PIK3C2B	5	SHC1	0	pull down	Wheeler M (2001)	1
STAT5A	4	CBL	7	affinity chromatography technology, two hybrid	Dieudonne FX (2013), Grossmann A (2015)	2
CBLB	3	ZAP70	5	affinity chromatography technology, affinity chromatography technology	Zhang Z (1999), Kumar S (2011)	2
NCK2	2	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Buvall L (2013), Buvall L (2013), Huttlin EL (2015), Huttlin EL (2017)	4
PIK3R1	6	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang S (1999), Takahashi Y (1999), Craddock BL (1997), Wu CJ (2000), Wu CJ (2001), Yu WM (2006)	6
GRB2	2	PDCD6IP	3	two hybrid, two hybrid	Bandyopadhyay S (2010), Wang J (2011)	2
CBL	7	ZAP70	5	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, x-ray crystallography	Lupher ML (1996), Meng W (1999), Wang HY (2001), Rao N (2000), Lupher ML (1997), Okabe S (2006), Zhang Z (1999), Lupher ML (1996), Dou H (2012), Dou H (2012), Gabrielsen M (2017)	11
CRKL	1	PTPN11	20	affinity chromatography technology	Chin H (1997)	1
VAV1	2	EGFR	5	affinity chromatography technology, unspecified method, two hybrid, protein complementation assay	Moores SL (2000), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	4
CDH1	4	EPS15	1	bioid	Guo Z (2014)	1
CRKL	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down	Gesbert F (1998), Gelkop S (2001), Ren SY (2005)	3
LYN	2	JAK2	1	pull down	Chin H (1998)	1
MUC1	0	SOS1	5	affinity chromatography technology, affinity chromatography technology	Pandey P (1995), Schroeder JA (2001)	2
EPS15	1	CRK	0	far western blotting, pull down, affinity chromatography technology, affinity chromatography technology	Schumacher C (1995), Schumacher C (1995), Brehme M (2009), Brehme M (2009)	4
TNK2	7	CTTN	1	enzymatic study, affinity chromatography technology	Kelley LC (2012), Kelley LC (2012)	2
SRC	2	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olayioye MA (1999), Cirri P (1997), Chang YJ (2004), Chang YJ (2004)	4
ERBB3	3	HGS	5	affinity chromatography technology, affinity chromatography technology	Fosdahl AM (2017), Fosdahl AM (2017)	2
GRB2	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Bennett AM (1994), Ward AC (1998), Yin T (1997), Tang J (1997), Tang H (1999), Hadari YR (1998), Zhang S (1999), Wong L (1996), Brehme M (2009), Craddock BL (1997), Bisson N (2011), Blagoev B (2003), Bisson N (2011), Tauchi T (1995), Huttlin EL (2017), Kapoor GS (2010), Kapoor GS (2010), Vogel W (1996), Vogel W (1996), Yu WM (2006)	21
VAV1	2	ZAP70	5	pull down, affinity chromatography technology	Katzav S (1994), Huby RD (1995)	2
PRKCA	7	CBL	7	enzymatic study, affinity chromatography technology, two hybrid	Liu Y (1999), Liu Y (1999), Grossmann A (2015)	3
VAV1	2	PLCG1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Bertagnolo V (1998), Bertagnolo V (1998), Braiman A (2006), Braiman A (2006), Braiman A (2006)	5
PML	7	PLCG1	6	affinity chromatography technology, affinity chromatography technology, biochemical	Ferguson BJ (2007), Ferguson BJ (2007), Ferguson BJ (2007)	3
ERBB2	6	PTPN6	0	two hybrid, affinity chromatography technology	Yao Z (2017), Yao Z (2017)	2
HDAC6	0	ERBB2	6	protein complementation assay	Deribe YL (2009)	1
EGFR	5	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Schulze WX (2006), Sakaguchi K (1998), Tong J (2009), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Burke P (2001), Katayama H (1999), Tong J (2008), Zhang L (1999), Levkowitz G (1999), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Foerster S (2013), Gotoh N (1994), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), Li J (2013), Prigent SA (1996), Prigent SA (1996), Grosse R (2000), Yao Z (2017), Wills MK (2014), Wills MK (2014), Kapoor GS (2010)	29
SRC	2	JAK2	1	affinity chromatography technology	Liang K (2010)	1
NCK1	0	PIK3R1	6	affinity chromatography technology	Gelkop S (2001)	1
CBLC	1	SRC	2	affinity chromatography technology, unspecified method, affinity chromatography technology, x-ray crystallography, pull down, enzymatic study	Ryan PE (2010), Takeshita K (2012), Takeshita K (2012), Takeshita K (2012), Kim M (2004), Kim M (2004)	6
CDH1	4	HSPA8	4	affinity chromatography technology, bioid	Catimel B (2005), Guo Z (2014)	2
EGFR	5	HDAC6	0	affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Gao YS (2010), Deribe YL (2009), Deribe YL (2009), Deribe YL (2009), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	7
GRB2	2	PTPN6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Kon-Kozlowski M (1996), Saci A (2002)	3
GRB2	2	AP2A1	1	affinity chromatography technology	Blagoev B (2003)	1
TRAF2	1	SH3KBP1	1	affinity chromatography technology	Narita T (2005)	1
EGFR	5	ANKS1A	3	unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
HSP90AB1	2	HSPA8	4	biochemical, affinity chromatography technology	Wan C (2015), Reidy M (2018)	2
TNK2	7	AR	3	affinity chromatography technology, pull down	Mahajan NP (2007), Mahajan NP (2007)	2
ERBB2	6	GAB1	3	enzymatic study	Fan YX (2013)	1
SRC	2	USP8	7	enzymatic study	Meijer IM (2013)	1
PLCG2	11	SHC1	0	affinity chromatography technology, affinity chromatography technology	Perskvist N (2000), Boudot C (2002)	2
PTPN1	2	CAV1	0	affinity chromatography technology	Caselli A (2002)	1
CBL	7	PTPN6	0	affinity chromatography technology	Kant AM (2002)	1
SRC	2	LYN	2	unspecified method	Pirozzi G (1997)	1
HSP90AA1	7	HSPA5	0	affinity chromatography technology	Gano JJ (2010)	1
CDC37	0	HSPA8	4	affinity chromatography technology	Li J (2013)	1
AP2M1	5	GAPDH	0	affinity chromatography technology	Brehme M (2009)	1
NCK1	0	GRB2	2	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
JUP	7	ERBB2	6	far western blotting, imaging technique	Kanai Y (1995), Chen TC (2014)	2
VAV2	6	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Moores SL (2000), Tong J (2009), Duan L (2011), Duan L (2011), Tong J (2008), Tong J (2014)	6
ERBB3	3	PTPN11	20	affinity chromatography technology, two hybrid	Crovello CS (1998), Yao Z (2017)	2
PIK3R1	6	GAB1	3	pull down, affinity chromatography technology, far western blotting, two hybrid, affinity chromatography technology, far western blotting, affinity chromatography technology	Bertagnolo V (1998), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Rocchi S (1998), Ingham RJ (1998), Ingham RJ (1998), Fan YX (2013)	7
AP2M1	5	HSPA8	4	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
TUBA1A	13	PDCD6IP	3	affinity chromatography technology	Schmidt MH (2003)	1
SOS1	5	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Qian X (2000), Foehr ED (2000), Park RK (1999), Chin H (1997), Wang Y (1999), Brehme M (2009), Brizzi MF (1996), Yu WM (2006), Klint P (1995)	9
SHC4	2	GRB2	2	affinity chromatography technology	Wills MK (2014)	1
NCK2	2	NCK1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EPS8	1	SOS1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Offenhaeuser N (2004), Scita G (1999), Jeganathan N (2016)	3
PTPN1	2	JAK2	1	affinity chromatography technology, enzymatic study	Myers MP (2001), Lund IK (2005)	2
PTPN11	20	JAK2	1	pull down, enzymatic study, enzymatic study, affinity chromatography technology	Yin T (1997), Yin T (1997), Tauchi T (1996), Maegawa H (1996)	4
JAK2	1	VAV1	2	affinity chromatography technology, enzymatic study, affinity chromatography technology	Shigematsu H (1997), Shigematsu H (1997), Matsuguchi T (1995)	3
EGFR	5	UBASH3B	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kowanetz K (2004), Raguz J (2007), Raguz J (2007), Tong J (2008), Foerster S (2013), Li J (2013), Tong J (2014), Li J (2013)	8
EGFR	5	CSK	3	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Schulze WX (2006), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
EGFR	5	PIK3R3	0	unspecified method, two hybrid, imaging technique, protein complementation assay	Jones RB (2006), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014)	4
SFN	1	CTNNB1	30	affinity chromatography technology	Mancini M (2015)	1
CDC37	0	HSPA5	0	affinity chromatography technology	Li J (2013)	1
GAB1	3	PLCG1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting	Ueno E (2001), Ueno E (2001), Holgado-Madruga M (1996), Holgado-Madruga M (1996)	4
PML	7	EGFR	5	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Kuo HY (2013), Kuo HY (2013), Kuo HY (2013), Kuo HY (2013)	4
EGFR	5	TNK2	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Lin Q (2010), Pao-Chun L (2009), Shen F (2007), Howlin J (2008), Howlin J (2008), Tong J (2008), Jones S (2014), Jones S (2014), Chua BT (2010)	9
HDAC6	0	PML	7	affinity chromatography technology	Joshi P (2013)	1
GRB2	2	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Skolnik EY (1993), Skolnik EY (1993), Puil L (1994), Satoh T (1996), Fixman ED (1996), Fixman ED (1996), Fixman ED (1996), Ishihara H (1997), Fournier E (1999), Ravichandran KS (1994), Lamprecht R (2002), Park RK (1999), Sakaguchi K (2001), Park RK (1999), Park RK (1999), Hallak H (2001), Yokote K (1994), Saci A (2002), Zhang S (1999), Lazar DF (1994), VanderKuur J (1995), Kanai M (1997), Spivak-Kroizman T (1994), Giordano V (1997), Drobot L (2005), Erdreich-Epstein A (1997), Takahashi Y (1999), Barber DL (1997), Ahn SC (2003), Odai H (1995), Panchamoorthy G (1996), Panchamoorthy G (1996), Brehme M (2009), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Zhang L (1999), Brizzi MF (1996), Brizzi MF (1996), Liu BA (2012), Bisson N (2011), Fukazawa T (1996), Bisson N (2011), Umehara H (2002), Oksvold MP (2001), Oksvold MP (2001), Li J (2013), Li J (2013), Ueno H (1995), Prigent SA (1996), Wills MK (2014), Rausch O (1997), Ho JM (2002), Ho JM (2002), Yu WM (2006), Klint P (1995)	57
PIK3R1	6	SH3KBP1	1	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid	Gout I (2000), Tossidou I (2010), Borthwick EB (2004), Borthwick EB (2004)	4
PML	7	CTNNB1	30	affinity chromatography technology, pull down, affinity chromatography technology	Satow R (2012), Satow R (2012), Shtutman M (2002)	3
UBASH3B	4	CRK	0	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009)	2
ERBB2	6	VAV1	2	unspecified method	Jones RB (2006)	1
PIK3R1	6	RET	3	pull down	Besset V (2000)	1
CDH1	4	CTTN	1	bioid	Guo Z (2014)	1
PIK3C2B	5	GRB2	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wheeler M (2001), Brehme M (2009), Bisson N (2011), Huttlin EL (2017)	4
HDAC6	0	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology	New M (2013), Watson GW (2016)	2
STUB1	4	HSP90AA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, enzymatic study, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down	Zhang L (2007), Zhang M (2005), Tateishi Y (2004), Tateishi Y (2004), Connell P (2001), Ko HS (2009), Kumar P (2007), Kumar P (2007), Wang L (2011), Stankiewicz M (2010), Graf C (2010), Kundrat L (2010), Kundrat L (2010), Kundrat L (2010), Kundrat L (2010), Morishima Y (2008), Zhou P (2003), Zhang M (2008), Grelle G (2006), Kim SA (2005), Arndt V (2005), Muller P (2012), Burch L (2004), Burch L (2004), Jang KW (2011), Schuelke JP (2010), Wang Q (2012), Shimamoto S (2013), Shimamoto S (2013), Shimamoto S (2013), Gano JJ (2010), Skarra DV (2011), Yang SW (2013), Grelle G (2006), Grelle G (2006), Narayan V (2015)	36
SRC	2	ERRFI1	1	enzymatic study	Park E (2015)	1
ERBB2	6	HSPA4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Citri A (2002), Jung Y (2007), Suzuki T (2011)	3
ERBB2	6	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scaltriti M (2009), Shtiegman K (2007), Haslekas C (2005), Riedemann J (2007), Burke P (2001), Meijer IM (2011), Chen TC (2014), Li J (2013), Li J (2013), Caiazza F (2010), Caiazza F (2010), Sharif A (2009)	12
SRC	2	ERBB2	6	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Ren Z (2002), Li X (2007), Liang K (2010), Liang K (2010), Shen JP (2017)	5
ERRFI1	1	ERBB2	6	affinity chromatography technology, two hybrid	Li J (2013), Arroyo R (2015)	2
JAK2	1	ERBB3	3	unspecified method	Jones RB (2006)	1
CBL	7	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kassenbrock CK (2002), Rafiq K (2011), Rellahan BL (2003), Vantler M (2006), Shishido T (2000), Shishido T (2000), Song JJ (2010), Sanjay A (2006), Sanjay A (2006), Tanaka S (1995), Tanaka S (1995), Tanaka S (1995), Szymkiewicz I (2004), Hashimoto S (2006)	14
CDK1	0	HSPA4	3	affinity chromatography technology	Garcia-Morales P (2007)	1
AP2M1	5	CRK	0	affinity chromatography technology	Brehme M (2009)	1
MUC1	0	ERBB3	3	affinity chromatography technology	Schroeder JA (2001)	1
HSPA4	3	JUP	7	biochemical	Kristensen AR (2012)	1
ERBB3	3	CSK	3	affinity chromatography technology	Schulze WX (2006)	1
EGFR	5	EPS8	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Burke P (2001), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
STUB1	4	HSPA4	3	pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down, pull down, enzymatic study, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ballinger CA (1999), Ballinger CA (1999), Ballinger CA (1999), Dai Q (2005), Tateishi Y (2004), Tateishi Y (2004), Ko HS (2009), Qian SB (2009), Kumar P (2007), Kumar P (2007), Wang L (2011), Wang L (2011), Wang L (2011), Graf C (2010), Kundrat L (2010), Matsumoto K (2011), Kundrat L (2010), Kundrat L (2010), Morishima Y (2008), Luo W (2010), Soss SE (2011), Zhou P (2003), Kalia LV (2011), Gao Y (2010), Gao Y (2010), Grelle G (2006), Rao SN (2010), Tetzlaff JE (2008), Kim SA (2005), Dai Q (2003), Zhang X (2011), Zhang X (2011), Muller P (2012), Jang KW (2011), Schuelke JP (2010), Jinwal UK (2012), Shimamoto S (2013), Shimamoto S (2013), Shimamoto S (2013), Mao RF (2013), Lee JS (2013), Lee JS (2013)	42
CDC37	0	CTTN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Li J (2013)	3
SHC1	0	JAK2	1	pull down, pull down	VanderKuur J (1995), Giordano V (1997)	2
EGFR	5	CISH	1	unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
SOS1	5	EGFR	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Qian X (2000), Qian X (1998), Buday L (1994), Tong J (2009), Kurada BR (2009), Tong J (2008), Foerster S (2013), Tong J (2014), Kapoor GS (2010)	9
SFN	1	ANKS1A	3	affinity chromatography technology	Benzinger A (2005)	1
CRK	0	AP2A1	1	affinity chromatography technology	Brehme M (2009)	1
VAV1	2	TUBA1A	13	affinity chromatography technology, affinity chromatography technology, pull down	Huby RD (1995), Huby RD (1995), Huby RD (1995)	3
CRK	0	GRB2	2	pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Riordan SM (2000), Matsuda M (1996), Okada S (1996), Okada S (1996), Garcia-Guzman M (2000), Brehme M (2009)	6
PTPN6	0	CTNND1	4	affinity chromatography technology, pull down, affinity chromatography technology	Keilhack H (2000), Keilhack H (2000), Keilhack H (2000)	3
CBLB	3	SHC1	0	affinity chromatography technology	Lavagna-Sevenier C (1998)	1
EGFR	5	BLK	4	unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
PRKCA	7	CTNNB1	30	affinity chromatography technology	Mertz JA (2011)	1
CBL	7	BLK	4	affinity chromatography technology	Panchamoorthy G (1996)	1
EPS15	1	HSPA5	0	affinity chromatography technology	Brehme M (2009)	1
CBL	7	CBLB	3	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Rorsman C (2016)	2
CDH1	4	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Davies G (2001), Kucerova D (2001), Oyama T (1994), Hazan RB (1997), Kinch MS (1995), Jiang MC (2002), Hazan RB (1998), Bonvini P (2001), Li Y (1998), Wendeler MW (2004), Shibata T (2003), Piedra J (2003), Oneyama C (2002), Navarro P (1993), Takahashi K (1997), Dobrosotskaya IY (2000), Dobrosotskaya IY (2000), Geng L (2000), Shibamoto S (1995), Rao RK (2002), Rao RK (2002), Huber AH (2001), Schmeiser K (1999), Pai R (2008), Tu LC (2007), Tu LC (2007), Smyth D (2012), Xue B (2005), Xue B (2005), Catimel B (2005), Huang Z (2012), Yan HX (2006), Yan HX (2006), Figueiredo J (2013), Ponce E (2014), Ponce E (2014), Ponce E (2014), Ribeiro AS (2013), Pinheiro H (2012), Geng F (2012), Lee HK (2007), Guo Z (2014)	42
CBL	7	ERBB2	6	pull down, affinity chromatography technology	Zhou P (2003), Bisaro B (2016)	2
STAT3	0	LYN	2	pull down	Schreiner SJ (2002)	1
AP2M1	5	CTNND1	4	affinity chromatography technology	Li J (2013)	1
STAT1	1	STAT5A	4	imaging technique	Chen TC (2014)	1
EGF	2	ERBB2	6	pull down	Stortelers C (2002)	1
PTPN1	2	STAT3	0	enzymatic study	Lund IK (2005)	1
EGFR	5	SOCS3	0	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Xia L (2002), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
CTNNB1	30	HSP90AB1	2	affinity chromatography technology	Tian Q (2004)	1
ERBB2	6	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method	Schulze WX (2006), Bourguignon LY (2001), Olayioye MA (1998), Li X (2007), Li X (2007), Crovello CS (1998), Jones RB (2006)	7
EGFR	5	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, affinity chromatography technology, enzymatic study	Schulze WX (2006), Tomic S (1995), Crovello CS (1998), Jones RB (2006), Yao Z (2017), Kapoor GS (2010), Vogel W (1996)	7
EGFR	5	JUP	7	pull down, affinity chromatography technology, two hybrid, protein complementation assay	Hazan RB (1998), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014)	4
CDH1	4	SLC3A2	5	bioid	Guo Z (2014)	1
APBB2	2	HSPA8	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGF	2	ERBB3	3	pull down	Stortelers C (2002)	1
PIK3R3	0	PIK3R1	6	affinity chromatography technology	Huttlin EL (2017)	1
ZAP70	5	PTPN6	0	pull down	Plas DR (1996)	1
STUB1	4	HSPA8	4	pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, pull down, pull down, pull down, pull down, affinity chromatography technology, enzymatic study, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, unspecified method, affinity chromatography technology, x-ray crystallography, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, enzymatic study	Ballinger CA (1999), Ballinger CA (1999), Ballinger CA (1999), Tateishi Y (2004), Tateishi Y (2004), Jiang J (2001), Wang L (2011), Wang L (2011), Wang L (2011), Stankiewicz M (2010), Yang M (2011), Yang M (2011), Urushitani M (2004), Grelle G (2006), Kim SA (2005), Arndt V (2005), Alberti S (2004), Meacham GC (2001), Smith MC (2013), Smith MC (2013), Matsumura Y (2013), Spooner RA (2008), Taipale M (2014), Taipale M (2014), Heimdal K (2014), Grelle G (2006), Grelle G (2006), Kamynina E (2007), Zhang H (2015), Zhang H (2015), Zhang H (2015), Li P (2015), Guo Y (2016), Zhang H (2017), Pakdaman Y (2017)	35
CBL	7	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park RK (1999), Gesbert F (1998), Erdreich-Epstein A (1997), Wang Y (1999), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Brizzi MF (1996), Fukazawa T (1996)	9
TUBA1A	13	CBL	7	affinity chromatography technology	Teckchandani AM (2005)	1
CDC37	0	AR	3	pull down	Rao J (2001)	1
CBL	7	VAV1	2	affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marengere LE (1997), Marengere LE (1997), Marengere LE (1997), Marengere LE (1997), Bertagnolo V (2001), Miura-Shimura Y (2003), Simmons A (2005), Shen M (2009), Shen M (2009), Lottin-Divoux S (2006), Lottin-Divoux S (2006), Peterson ME (2008)	12
HDAC6	0	GAPDH	0	affinity chromatography technology	Watson GW (2016)	1
CDH1	4	HSPA5	0	affinity chromatography technology, bioid	Catimel B (2005), Guo Z (2014)	2
PRKCA	7	HDAC6	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology	Zhu J (2011), Zhu J (2011), Mertz JA (2011), Mertz JA (2011), Mertz JA (2011)	5
CBL	7	TRAF2	1	affinity chromatography technology	Xu L (2017)	1
CBLB	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Ettenberg SA (1999), Lavagna-Sevenier C (1998), Lavagna-Sevenier C (1998), Elly C (1999), Bandyopadhyay S (2010), Vinayagam A (2011), Bisson N (2011), Blagoev B (2003), Rolland T (2014), Huttlin EL (2017)	10
CSK	3	SRC	2	pull down	Sabe H (1994)	1
CDK1	0	HDAC6	0	affinity chromatography technology	Galindo-Moreno M (2017)	1
HSPA5	0	HDAC6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rao R (2010), Rao R (2010), New M (2013)	3
ERBB2	6	STUB1	4	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Xu W (2002), Jung Y (2007), Jung Y (2007), Zhou P (2003), Zhou P (2003), Li X (2007), Li X (2007), Xu W (2002), Bisaro B (2016)	9
CAV1	0	CSK	3	two hybrid	Cao H (2002)	1
CDH1	4	NCK1	0	bioid	Guo Z (2014)	1
AP2M1	5	CDH1	4	affinity chromatography technology	Li J (2013)	1
CBLB	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavagna-Sevenier C (1998), Elly C (1999), Elly C (1999), Alcazar I (2009), Fang D (2001)	5
CRKL	1	SHC1	0	affinity chromatography technology	Chin H (1997)	1
TNK2	7	CRKL	1	affinity chromatography technology	Mahendrarajah N (2017)	1
EGFR	5	PLCG1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tvorogov D (2002), Bedrin MS (1997), Crovello CS (1998), Choi JH (2003), Jones RB (2006), Tong J (2014), Egan JE (2002), Wu D (2009), Wu D (2009)	9
HSPA4	3	HSPA8	4	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical	Hidalgo-de-Quintana J (2008), Havugimana PC (2012), Taipale M (2014), Taipale M (2014), Wan C (2015)	5
GRB2	2	HSPA5	0	two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Brehme M (2009)	2
SFN	1	SH2D3A	3	affinity chromatography technology	Benzinger A (2005)	1
TNK2	7	CDC37	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Mahendrarajah N (2017)	2
HSPA8	4	GAPDH	0	biochemical	Wan C (2015)	1
ERBB2	6	VAV2	6	unspecified method	Jones RB (2006)	1
CBLC	1	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PIK3C2B	5	EGFR	5	pull down, two hybrid, protein complementation assay, affinity chromatography technology	Wheeler M (2001), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
HGS	5	SH3KBP1	1	affinity chromatography technology	Ronning SB (2011)	1
CBLB	3	TRAF2	1	affinity chromatography technology	Xu L (2017)	1
CTNNB1	30	AR	3	pull down, two hybrid, two hybrid, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Yang F (2002), Yang F (2002), Masiello D (2004), Song LN (2004), Amir AL (2003), Amir AL (2003), Mulholland DJ (2003), Mulholland DJ (2003), Pawlowski JE (2002), Mulholland DJ (2003), Levy L (2004)	11
EGFR	5	CRK	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Schulze WX (2006), Hashimoto Y (1998), Hashimoto Y (1998), Katayama H (1999), Ota S (1998), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	9
VAV1	2	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	Song JS (1996), Ye ZS (1994), Ye ZS (1994), Germani A (1999), Lee IS (1997)	5
CDH1	4	HSPA1A	0	bioid	Guo Z (2014)	1
JAK2	1	PLCG1	6	affinity chromatography technology	Chang YJ (2004)	1
EGFR	5	SH3GL2	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schmidt MH (2004), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Liu W (2014), Liu W (2014)	6
CBLC	1	SHC1	0	two hybrid	Vinayagam A (2011)	1
SRC	2	PTPN11	20	enzymatic study	Vogel W (1996)	1
CDH1	4	EGFR	5	affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, bioid	Pece S (2000), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Li J (2013), Guo Z (2014)	6
EGFR	5	ZAP70	5	unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
CRK	0	TUBA1A	13	affinity chromatography technology	Brehme M (2009)	1
AR	3	STAT3	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Matsuda T (2001), Ueda T (2002), Yamamoto T (2003), Yamamoto T (2003)	4
EGFR	5	STAT5A	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, enzymatic study, imaging technique	Schulze WX (2006), Schulze WX (2006), Olayioye MA (1999), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Fan QW (2013), Latha K (2013)	8
CBLB	3	PIK3R2	3	affinity chromatography technology	Alcazar I (2009)	1
HSP90AA1	7	GAPDH	0	affinity chromatography technology, biochemical	Falsone SF (2005), Wan C (2015)	2
UBASH3B	4	ERRFI1	1	affinity chromatography technology, affinity chromatography technology	Li J (2013), Li J (2013)	2
SHC1	0	PIK3R1	6	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harrison-Findik D (1995), Ren SY (2005), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Lee DY (2010)	6
CRK	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique	Gelkop S (2001), Gelkop S (2001), Garcia-Guzman M (2000), Brehme M (2009), Grossmann A (2015), Chen TC (2014)	6
JAK2	1	HSP90AA1	7	affinity chromatography technology	Cheng MB (2010)	1
ERBB2	6	PIK3R3	0	unspecified method	Jones RB (2006)	1
SHC1	0	PLCG1	6	affinity chromatography technology	Fixman ED (1996)	1
SH3KBP1	1	SH3GL2	1	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid	Soubeyran P (2002), Soubeyran P (2002), Soubeyran P (2002), Schmidt MH (2004), Schmidt MH (2004), Vinayagam A (2011)	6
EGFR	5	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Yuan ZL (2004), Olayioye MA (1999), Lo HW (2005), Lo HW (2005), Crovello CS (1998), Jaganathan S (2011), Jaganathan S (2011), Andl CD (2004), Lo HW (2010), Foerster S (2013), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), de la Iglesia N (2008), Fan QW (2013), Fan QW (2013)	18
JAK2	1	STAT3	0	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Ram PA (1997), Manea A (2010), Andl CD (2004), Kamakura S (2004), He K (2013), Kucia-Tran JA (2016), M L (2016)	7
HSP90AB1	2	TRAF2	1	imaging technique	Chen TC (2014)	1
EGFR	5	PLCG2	11	unspecified method, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014)	5
SHC1	0	STAT5A	4	affinity chromatography technology	Dinerstein-Cali H (2000)	1
EGFR	5	CDK1	0	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Tong J (2008), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014)	4
PIK3R2	3	PIK3R3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Huttlin EL (2015), Huttlin EL (2017)	3
CAV1	0	SRC	2	pull down	Li S (1996)	1
CRK	0	SOS2	3	affinity chromatography technology	Brehme M (2009)	1
SH3KBP1	1	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000), Petrelli A (2002), Soubeyran P (2002), Soubeyran P (2002), Szymkiewicz I (2002), Borinstein SC (2000), Schmidt MH (2006), Schmidt MH (2004), Schmidt MH (2004), Verdier F (2002), Verdier F (2002), Feshchenko EA (2004), Chandra V (2010), Niiro H (2012), Feng L (2011), Havrylov S (2009), Zhang J (2009), Zhang J (2009), Ababou A (2009), Le Bras S (2007), Jozic D (2005), Kowanetz K (2004), Kowanetz K (2003), Kowanetz K (2003), Tibaldi EV (2003), Tibaldi EV (2003), Take H (2000), Take H (2000), Schroeder B (2012), Schroeder B (2012), Peruzzi G (2007), Selbach M (2006), Sato S (2013), Taipale M (2014), Taipale M (2014), Diesenberg K (2015), Petrelli A (2002), Huttlin EL (2017)	39
CDH1	4	CTNND1	4	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, bioid	Daniel JM (1995), Daniel JM (1995), Ireton RC (2002), Kinch MS (1995), Hazan RB (1998), Bonne S (2003), Piedra J (2003), Piedra J (2003), Shibamoto S (1995), Shibamoto S (1995), Ohkubo T (1999), Ohkubo T (1999), Ishiyama N (2010), Ishiyama N (2010), Ishiyama N (2010), Chen Y (2009), Smyth D (2012), Del Valle-Perez B (2011), Figueiredo J (2013), Ribeiro AS (2013), Pinheiro H (2012), Guo Z (2014)	22
UBASH3B	4	CBL	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kowanetz K (2004), Kowanetz K (2004), Raguz J (2007), Hoeller D (2006), Peruzzi G (2007), Brehme M (2009)	6
NCK1	0	ERBB3	3	unspecified method	Jones RB (2006)	1
CRK	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Larsson H (1999)	2
SHC1	0	HSPA5	0	affinity chromatography technology	Brehme M (2009)	1
ZAP70	5	PLCG1	6	affinity chromatography technology, affinity chromatography technology, pull down	Nel AE (1995), Braiman A (2006), Hubert P (1996)	3
STAT3	0	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology	Gunaje JJ (2001), Spiekermann K (2001), Xia L (2002), Chen TC (2014), Li X (2015), Ghosh MK (2005), Huttlin EL (2017)	7
CBL	7	GAPDH	0	affinity chromatography technology	Feshchenko EA (2004)	1
AP2M1	5	TUBA1A	13	affinity chromatography technology	Brehme M (2009)	1
JAK2	1	PTPN6	0	affinity chromatography technology, affinity chromatography technology	Jiao H (1996), Wu DW (2000)	2
EPS15	1	HSPA8	4	affinity chromatography technology	Brehme M (2009)	1
CTNND1	4	CTTN	1	affinity chromatography technology, pull down	Martinez MC (2003), Martinez MC (2003)	2
ERBB3	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Li J (2013)	3
EGFR	5	RET	3	two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Bhinge K (2017), Bhinge K (2017)	4
CD44	1	VAV2	6	affinity chromatography technology	Bourguignon LY (2001)	1
STAT3	0	PIK3R2	3	two hybrid	Grossmann A (2015)	1
ERBB3	3	PTPN12	2	two hybrid	Yao Z (2017)	1
LYN	2	CBL	7	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Taher TE (2002), Dombrosky-Ferlan PM (1997), Kaabeche K (2004), Wu J (2008), Tanaka S (1995), Marcilla A (1995)	6
CDH1	4	STAT1	1	bioid	Guo Z (2014)	1
CBL	7	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Gesbert F (1998), Gesbert F (1998), Zhang S (1999), Dufour C (2008), Feshchenko EA (2004), Kassenbrock CK (2002), Fang D (2001), Valiya Veettil M (2011), Miao H (2002), Miao H (2002), Ueno H (1998), Gelkop S (2001), Wang Y (1999), Saci A (2000), Matsuo T (1996), Matsuo T (1996), Jackson JG (2000), Meisner H (1995), Saci A (1999), Saci A (1999), Beckwith M (1996), Beckwith M (1996), Song JJ (2010), Hartley D (1996), Finkelstein LD (2000), Ren SY (2005), Hunter S (1997), Hunter S (1997), Jain SK (1997), Jain SK (1997), Swaminathan G (2007), van Leeuwen JE (1999), Ren SY (2005), Ren SY (2005), Alcazar I (2009), Liu YC (1997), Matsuo T (1996), Matsuo T (1996), Lottin-Divoux S (2006), Kitanaka A (1996), Liu YC (1997), Grossmann AH (2004), Panchamoorthy G (1996), Panchamoorthy G (1996), Chernock RD (2001), Chernock RD (2001), Fukazawa T (1995), Fukazawa T (1995), Brehme M (2009), Hakak Y (2000), Hakak Y (2000), Fukazawa T (1995), Liu Y (1999), Cerboni C (1998), Cerboni C (1998), Momose H (2003), Fukazawa T (1996), Fukazawa T (1996), Bulut GB (2013), Bulut GB (2013), Grossmann A (2015)	61
ERBB3	3	HSP90AB1	2	affinity chromatography technology	Li J (2013)	1
CD44	1	CAV1	0	imaging technique	Su YJ (2011)	1
CSK	3	ZAP70	5	pull down	Catipovic B (1996)	1
PLCG1	6	SRC	2	affinity chromatography technology	Dhar A (1994)	1
NCK1	0	TUBA1A	13	affinity chromatography technology	Jeong DG (2007)	1
CTNND1	4	SRC	2	affinity chromatography technology	Piedra J (2003)	1
EGFR	5	CTTN	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
GRB2	2	ERRFI1	1	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Bisson N (2011), Wang J (2011), Wang J (2011), Li J (2013), Li J (2013), Ying H (2010), Huttlin EL (2017)	8
HDAC6	0	YWHAZ	1	enzymatic study	Mortenson JB (2015)	1
EGFR	5	TRAF2	1	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2008), Puliyappadamba VT (2013), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
TNK2	7	GRB2	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Satoh T (1996), Kato-Stankiewicz J (2001), Bandyopadhyay S (2010), Lin Q (2010), Lin Q (2012), Yeow-Fong L (2005), Chan W (2011), Yokoyama N (2003), Huttlin EL (2017), Mahendrarajah N (2017)	10
CDH1	4	SH3KBP1	1	bioid	Guo Z (2014)	1
LYN	2	PIK3R3	0	affinity chromatography technology, affinity chromatography technology	Zhu J (2013), Zhu J (2013)	2
HSPA8	4	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down	Polanowska-Grabowska R (1997), Giommarelli C (2010), Gano JJ (2010), Skarra DV (2011), Wan C (2015), Sun L (2012)	6
SRC	2	AR	3	affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid	Migliaccio A (2000), Unni E (2004), Powell SM (2004), Dotzlaw H (2003)	4
JAK2	1	CALM1	0	affinity chromatography technology	Garnovskaya MN (2003)	1
MUC1	0	CTNNB1	30	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Yamamoto M (1997), Li Y (2003), Li Y (1998), Li Y (1998), Schroeder JA (2003), Yamamoto M (1997), Li Y (2001), Li Y (2001), Ren J (2002), Li Y (2001), Li Y (2001)	11
EGFR	5	HSPA8	4	protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Deribe YL (2009), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), Yao Z (2017)	8
ERBB3	3	HSPA1A	0	affinity chromatography technology	Li J (2013)	1
SRC	2	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Narita T (2005), Schroeder B (2012)	2
TNK2	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mahajan NP (2005), Mahajan NP (2005), Taipale M (2012), Gao B (2013), Mahendrarajah N (2017), Mahendrarajah N (2017), Mahendrarajah N (2017)	7
AP2M1	5	HSPA1A	0	affinity chromatography technology	Li J (2013)	1
STAT1	1	TNK2	7	affinity chromatography technology	Mahendrarajah N (2017)	1
SOS1	5	PTPN6	0	affinity chromatography technology	Kon-Kozlowski M (1996)	1
PTPN6	0	CDK1	0	enzymatic study	Frank C (2004)	1
GRB2	2	RET	3	pull down, pull down, affinity chromatography technology, pull down	Borrello MG (1994), Pandey A (1995), Scott RP (2005), Besset V (2000)	4
NCK1	0	SOS1	5	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Wunderlich L (1999), Hu Q (1995), Hu Q (1995), Okada S (1996), Okada S (1996), Braverman LE (1999)	6
SRC	2	ERBB3	3	unspecified method	Jones RB (2006)	1
PTPN12	2	CSK	3	bioid	St-Denis N (2016)	1
CBL	7	SOS1	5	affinity chromatography technology	Wang Y (1999)	1
ERBB3	3	PTPN6	0	two hybrid	Yao Z (2017)	1
ZAP70	5	SHC1	0	affinity chromatography technology, enzymatic study, affinity chromatography technology	Pacini S (1998), Pacini S (1998), Jin HS (2013)	3
PLCG2	11	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Boudot C (2002), Boudot C (2002)	2
PDCD6IP	3	SH3GL2	1	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Schmidt MH (2004), Schmidt MH (2004), Ichioka F (2007), Ichioka F (2007)	4
PTPN12	2	NCK2	2	bioid	St-Denis N (2016)	1
EPS15	1	HGS	5	pull down, two hybrid, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Bean AJ (2000), Bean AJ (2000), Bache KG (2003), Roxrud I (2008), Roxrud I (2008), Yan Q (2005), Gschweitl M (2016)	7
ERBB3	3	ZAP70	5	unspecified method	Jones RB (2006)	1
SRC	2	TNK2	7	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down	Chan W (2009), Modzelewska K (2006), Chan W (2011), Chan W (2011), Chan W (2011), Yokoyama N (2003)	6
GAB1	3	SHC1	0	affinity chromatography technology, far western blotting, affinity chromatography technology	Ingham RJ (1998), Ingham RJ (1998), van den Akker E (2004)	3
EGFR	5	TUBA1A	13	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
RET	3	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Yuan ZL (2004), Hwang JH (2003), Schuringa JJ (2001), Chen TC (2014)	4
MUC1	0	CTNND1	4	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Li Y (2001), Li Y (2001), Li Y (2001), Li Y (2001)	4
VAV1	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Bertagnolo V (1998), Bertagnolo V (1998), Bertagnolo V (1998), Shigematsu H (1997), Shigematsu H (1997), Shigematsu H (1997)	6
PIK3R1	6	SOS1	5	imaging technique	Chen TC (2014)	1
HSPA5	0	HSPA1A	0	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Hein MY (2015)	3
ERBB2	6	BLK	4	unspecified method	Jones RB (2006)	1
EPS8	1	BAIAP2	6	two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Rual JF (2005), Funato Y (2004), Funato Y (2004), Rolland T (2014), Huttlin EL (2015), Grossmann A (2015), Huttlin EL (2017)	7
CDK1	0	PML	7	enzymatic study	Yuan WC (2011)	1
GRB2	2	SOS2	3	affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Scholler JK (2000), Yang SS (1995), Bandyopadhyay S (2010), Brehme M (2009), Bisson N (2011), Wang J (2011), Huttlin EL (2017)	7
SHC1	0	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009), Ota S (1998), Larsson H (1999)	4
SLC3A2	5	CD44	1	biochemical	Havugimana PC (2012)	1
LYN	2	MUC1	0	pull down, affinity chromatography technology	Li Y (2003), Li Y (2003)	2
PTPN11	20	PTPN6	0	affinity chromatography technology	Li X (2016)	1
SRC	2	GRB2	2	affinity chromatography technology, affinity chromatography technology	Wan KF (2003), Saci A (2002)	2
CRK	0	PTPN1	2	pull down	Liu F (1996)	1
SRC	2	PTPN6	0	enzymatic study	Frank C (2004)	1
YWHAZ	1	CDC25A	2	two hybrid, affinity chromatography technology, affinity chromatography technology	Wang Z (2002), Li X (2016), Huttlin EL (2017)	3
EPS15	1	TRAF2	1	affinity chromatography technology	Brehme M (2009)	1
PIK3R2	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Huttlin EL (2015), Huttlin EL (2017)	3
CD44	1	ERBB2	6	affinity chromatography technology, fluorescent resonance energy transfe	Tsatas D (2002), Ivanov AA (2017)	2
HSP90AA1	7	PRKCA	7	affinity chromatography technology	Taipale M (2012)	1
EPS8	1	SHC1	0	affinity chromatography technology, pull down	Matoskova B (1995), Matoskova B (1995)	2
MUC1	0	SRC	2	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology	Li Y (2001), Li Y (2001), Li Y (2001), Li Y (2001), Li Y (2001), Bernier AJ (2011)	6
PTPN12	2	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology	Charest A (1997), Charest A (1997), Bisson N (2011)	3
HSP90AA1	7	AR	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Veldscholte J (1992), Nemoto T (1992), Zoubeidi A (2007), DaSilva J (2009), Chymkowitch P (2011), Gibbs A (2009), Wolf SS (2007), Luo J (2015), Kwegyir-Afful AK (2015), Ni L (2010), McClurg UL (2016)	11
HSP90AB1	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Cheng MB (2010), Gano JJ (2010), Skarra DV (2011), Kristensen AR (2012), Taipale M (2014), Taipale M (2014), Wan C (2015), Hein MY (2015)	8
CALM1	0	HSPA4	3	pull down	Ning YM (1995)	1
JAK2	1	STAT1	1	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Cheng MB (2010), Cheng MB (2010), Manea A (2010), Andl CD (2004), Chang YJ (2004)	5
ERBB3	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hellyer NJ (2001), Lin J (1999), Crovello CS (1998), Graus-Porta D (1997), Jones RB (2006), Li J (2013), Servidei T (2008), Servidei T (2008), Ritch PS (2005), Tang X (2002)	10
ERBB2	6	PLCG2	11	unspecified method, imaging technique	Jones RB (2006), Chen TC (2014)	2
PIK3R2	3	HSPA8	4	affinity chromatography technology	Brehme M (2009)	1
CDH1	4	ERBB2	6	bioid	Guo Z (2014)	1
GRB2	2	HSPA8	4	affinity chromatography technology	Brehme M (2009)	1
ERBB2	6	STAT1	1	unspecified method, imaging technique	Jones RB (2006), Chen TC (2014)	2
NCK1	0	EGFR	5	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay	Tang J (1997), Li W (1992), Braverman LE (1999), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	6
EGFR	5	HGS	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Umebayashi K (2008), Morino C (2004), Meijer IM (2013), Sun Y (2013), Ali N (2013), Tan X (2015)	6
NCK2	2	ERBB3	3	unspecified method	Jones RB (2006)	1
EGFR	5	CBLB	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Schulze WX (2006), Ettenberg SA (1999), Davies GC (2006), Davies GC (2006), Tong J (2009), Ettenberg SA (2001), Tong J (2008), Levkowitz G (1999), Tong J (2014)	9
BLK	4	STAT3	0	two hybrid	Rolland T (2014)	1
HSP90AA1	7	ERBB3	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Li J (2013)	2
EGFR	5	SFN	1	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Wu SL (2006), Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Li J (2013)	5
EGFR	5	CAV1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, pull down, biochemical	Couet J (1997), Couet J (1997), Khan EM (2006), Feldman R (2009), Hua H (2003), Wu SL (2006), Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Park WY (2000), Abulrob A (2004), Abulrob A (2004)	12
ERBB2	6	SH2D3A	3	unspecified method	Jones RB (2006)	1
BLK	4	PLCG2	11	pull down	Pleiman CM (1993)	1
PTPN1	2	EGFR	5	x-ray crystallography, enzymatic study, two hybrid, protein complementation assay, affinity chromatography technology, pull down, pull down	Sarmiento M (2000), Zhang ZY (1996), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Milarski KL (1993), Milarski KL (1993)	7
CBLC	1	ZAP70	5	unspecified method	Takeshita K (2012)	1
SHC1	0	RET	3	affinity chromatography technology, pull down, affinity chromatography technology	Arighi E (1997), Arighi E (1997), Borrello MG (1994)	3
HSP90AB1	2	CDC37	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Erazo T (2013), Erazo T (2013), Taipale M (2014), Taipale M (2014), Taipale M (2014), Taipale M (2014), Hein MY (2015), Li J (2013), Karras GI (2017), Synoradzki K (2015)	10
PIK3R1	6	PLCG2	11	imaging technique	Chen TC (2014)	1
TNK2	7	NCK1	0	pull down, affinity chromatography technology	Chan W (2011), Hein MY (2015)	2
CAV1	0	AR	3	affinity chromatography technology, two hybrid, pull down	Lu ML (2001), Lu ML (2001), Lu ML (2001)	3
BLK	4	GAPDH	0	affinity chromatography technology	So J (2015)	1
CTNNB1	30	CBL	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Chitalia V (2013), Chitalia V (2013), Chitalia V (2013), Shivanna S (2015)	4
GRB2	2	HSP90AB1	2	affinity chromatography technology	Brehme M (2009)	1
SHC1	0	AP2A1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013), Huttlin EL (2017)	3
AR	3	STUB1	4	affinity chromatography technology, pull down, enzymatic study, unspecified method, two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology	DaSilva J (2009), Chymkowitch P (2011), Chymkowitch P (2011), Rees I (2006), He B (2004), He B (2004), Schuelke JP (2010), McClurg UL (2016), Wang J (2016), Wang J (2016), Wang J (2016)	11
STAT1	1	HSP90AB1	2	two hybrid	Bandyopadhyay S (2010)	1
CDK1	0	JUP	7	affinity chromatography technology	Malty RH (2017)	1
CBL	7	VAV2	6	affinity chromatography technology, affinity chromatography technology, pull down	Duan L (2011), Duan L (2011), Tartare-Deckert S (2001)	3
CBLB	3	UBASH3B	4	two hybrid	Rolland T (2014)	1
CDH1	4	YWHAZ	1	bioid	Guo Z (2014)	1
CBL	7	YWHAZ	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Robertson H (1997), Subramanian RR (2001), Wang H (1998)	3
UBASH3B	4	HSPA8	4	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
CRKL	1	STAT5A	4	affinity chromatography technology, pull down, affinity chromatography technology	Ota J (1998), Ota J (1998), Oda A (1998)	3
EGFR	5	CTNND1	4	pull down, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hazan RB (1998), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), Shrestha H (2016)	7
CTNNB1	30	TUBA1A	13	affinity chromatography technology	Tian Q (2004)	1
HSP90AA1	7	SRC	2	affinity chromatography technology, affinity chromatography technology	Hutchison KA (1992), Tsutsumi S (2012)	2
SOS2	3	SHC1	0	affinity chromatography technology, affinity chromatography technology	Qian X (2000), Brehme M (2009)	2
EGFR	5	SHC4	2	two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, pull down	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Wills MK (2014), Wills MK (2014)	5
STUB1	4	HSPA1A	0	pull down, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ballinger CA (1999), Ballinger CA (1999), Imai Y (2002), Havugimana PC (2012), Jinwal UK (2012), Yang SW (2013), Choi JR (2016), Schoenbuehler B (2016)	8
PRKCA	7	EGFR	5	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Gauthier ML (2003), Gauthier ML (2003), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
NCK1	0	APBB2	2	affinity chromatography technology	Hein MY (2015)	1
HSPA5	0	NCK1	0	affinity chromatography technology	Misra UK (2005)	1
UBASH3B	4	HSPA5	0	affinity chromatography technology	Brehme M (2009)	1
CBLB	3	NCK2	2	two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Rual JF (2005), Rolland T (2014), Huttlin EL (2015), Yu H (2011), Huttlin EL (2017)	5
CDH1	4	HSP90AA1	7	affinity chromatography technology	Catimel B (2005)	1
CDH1	4	CBL	7	bioid	Guo Z (2014)	1
EGFR	5	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	6
PLCG1	6	ERBB3	3	unspecified method	Jones RB (2006)	1
EGF	2	EGFR	5	pull down, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, x-ray crystallography, x-ray crystallography, pull down, pull down, pull down, imaging technique	Stortelers C (2002), Wong L (1999), Tong J (2009), Tong J (2008), Chen TC (2014), Gomez-Suaga P (2014), Ogiso H (2002), Ferguson KM (2003), Ferguson KM (2003), Bessman NJ (2014), Zheng Y (2015), Latha K (2013)	12
UBASH3B	4	HSP90AA1	7	affinity chromatography technology	Brehme M (2009)	1
ERBB3	3	CRKL	1	unspecified method	Jones RB (2006)	1
UBASH3B	4	HSP90AB1	2	affinity chromatography technology	Brehme M (2009)	1
ERBB2	6	CISH	1	unspecified method	Jones RB (2006)	1
ERBB2	6	PIK3R2	3	pull down, unspecified method	Gout I (1992), Jones RB (2006)	2
PLCG1	6	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Pei Z (1997), Pei Z (1997), Nel AE (1995), Scholler JK (2000), Choi JH (2005), Choi JH (2005)	6
CALM1	0	CBL	7	affinity chromatography technology, affinity chromatography technology	Singh VK (2012), Singh VK (2012)	2
ERBB3	3	PIK3R3	0	unspecified method, affinity chromatography technology	Jones RB (2006), Li J (2013)	2
CDC37	0	ERBB2	6	affinity chromatography technology	Li J (2013)	1
CDC37	0	STUB1	4	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
HSP90AA1	7	HSPA1A	0	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Kanelakis KC (2002), Gano JJ (2010), Falsone SF (2005), Brychzy A (2003), Scholz GM (2001), Scholz GM (2001)	6
CAV2	0	CAV1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Breuza L (2002), Scherer PE (1997), Scherer PE (1997), Sowa G (2008)	4
EGFR	5	STUB1	4	protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Deribe YL (2009), Wang T (2014), Wang T (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Chung C (2016), Chung C (2016)	8
SFN	1	CBL	7	affinity chromatography technology	Subramanian RR (2001)	1
ERBB3	3	HSPA5	0	affinity chromatography technology	Li J (2013)	1
SHC1	0	UBASH3B	4	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
SFN	1	ERRFI1	1	affinity chromatography technology, affinity chromatography technology	Benzinger A (2005), Benzinger A (2005)	2
EGFR	5	CDC37	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavictoire SJ (2003), Foerster S (2013), Li J (2013), Li J (2013)	4
HSPA5	0	HSPA8	4	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015)	3
CTNNB1	30	HSPA8	4	affinity chromatography technology	Tian Q (2004)	1
EGFR	5	CALM1	0	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, pull down	Li H (2004), Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Aifa S (2002)	5
GRB2	2	PIK3R2	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Brehme M (2009), Brehme M (2009), Bisson N (2011)	4
HSP90AA1	7	CAV1	0	affinity chromatography technology	Ji Y (2007)	1
EPS15	1	AP2A1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	van Delft S (1997), Kariya K (2000), Confalonieri S (2000), Brehme M (2009)	4
EGFR	5	CTNNB1	30	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hazan RB (1998), Schroeder JA (2002), Takahashi K (1997), Li J (2013)	4
JAK2	1	PTPN12	2	affinity chromatography technology	Horsch K (2001)	1
TUBA1A	13	GAPDH	0	biochemical	Kristensen AR (2012)	1
CDC37	0	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Garcia-Morales P (2007)	3
ANKS1A	3	PIK3R3	0	two hybrid	Grossmann A (2015)	1
EGFR	5	GAB1	3	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, enzymatic study, affinity chromatography technology	Kameda H (2001), Tong J (2008), Kotlyar M (2015), Petschnigg J (2014), Lehr S (1999), Mueller KL (2012)	6
SHC1	0	SRC	2	pull down	Schueller AC (2008)	1
CRK	0	HSPA5	0	affinity chromatography technology	Brehme M (2009)	1
ERBB2	6	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid	Schulze WX (2006), Wong L (1999), Olayioye MA (1998), Crovello CS (1998), Jones RB (2006), Yao Z (2017)	6
CTNNB1	30	PIK3R1	6	pull down, imaging technique	Espada J (1999), Chen TC (2014)	2
CDH1	4	SFN	1	bioid	Guo Z (2014)	1
ZAP70	5	GRB2	2	affinity chromatography technology, affinity chromatography technology	Nel AE (1995), Jin HS (2013)	2
CBLC	1	LYN	2	pull down	Keane MM (1999)	1
CDC37	0	HSPA1A	0	affinity chromatography technology	Li J (2013)	1
GSTP1	0	TRAF2	1	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, imaging technique	Wu Y (2006), Wu Y (2006), De Luca A (2014), De Luca A (2014), Chen TC (2014)	5
CRK	0	STAT5A	4	imaging technique	Chen TC (2014)	1
EGFR	5	PDCD6IP	3	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Schmidt MH (2004), Schmidt MH (2003), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
HSP90AA1	7	CDC37	0	x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Roe SM (2004), Silverstein AM (1998), Mollapour M (2010), Basso AD (2002), Tsutsumi S (2012), De Nardo D (2005), Sarkar S (2012), Gano JJ (2010), Taipale M (2012), Skarra DV (2011), Zhang H (2004), Taipale M (2014), Taipale M (2014), Mollapour M (2014), Hein MY (2015), Hein MY (2015), Li J (2013), Woodford MR (2016), Shao J (2003), Scholz GM (2001), Sun L (2012), Sun L (2012), Woodford MR (2016), Synoradzki K (2015)	24
CBL	7	CRKL	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Alsayed Y (2000), Alsayed Y (2000), Kyono WT (1998), Lin H (2001), Park RK (1998), Taher TE (2002), Sattler M (1997), Erdreich-Epstein A (1999), Erdreich-Epstein A (1999), Sattler M (1997), Sattler M (1997), Gesbert F (1998), Chin H (1997), Feshchenko EA (2004), Izadi KD (1998), de Jong R (1995), de Jong R (1995), Boussiotis VA (1997), Boussiotis VA (1997), Barber DL (1997), Uemura N (1999), Okabe S (2006), Alsayed Y (2000), Alsayed Y (2000), Brenner B (2001), van Leeuwen JE (1999), Ribon V (1996), Bhat A (1997), Bhat A (1997), Huang JY (2000), Chernock RD (2001), Chernock RD (2001), Grossmann AH (2004), Sakamoto H (2004), Nishihara T (2003), Peterson ME (2008), Fukazawa T (1996), Martelli MP (2001), Joshi S (2014), Grossmann A (2015)	40
CRK	0	CBLB	3	affinity chromatography technology, two hybrid, two hybrid	Brehme M (2009), Grossmann A (2015), Grossmann A (2015)	3
AP2M1	5	CTNNB1	30	affinity chromatography technology	Li J (2013)	1
EGFR	5	AR	3	affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique	Bonaccorsi L (2004), Bonaccorsi L (2004), Bonaccorsi L (2004), Bonaccorsi L (2004)	4
APBB2	2	TUBA1A	13	affinity chromatography technology	Huttlin EL (2015)	1
CAV1	0	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Li Y (2008), Rodriguez DA (2009)	2
HDAC6	0	TUBA1A	13	enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Matsuyama A (2002), Hubbert C (2002), Zhao Z (2010), Zhao Z (2010), New M (2013)	6
CRK	0	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, two hybrid	Gesbert F (1998), Husson H (1997), Ingham RJ (1996), Ingham RJ (1996), Delehanty LL (2003), Garcia-Guzman M (2000), Garcia-Guzman M (2000), Barber DL (1997), Buday L (1996), Sawasdikosol S (1996), Sawasdikosol S (1996), Thien CB (1997), van Leeuwen JE (1999), Ribon V (1996), Lottin-Divoux S (2006), Reedquist KA (1996), Brehme M (2009), Brehme M (2009), Ota S (1998), Peterson ME (2008), Liu BA (2012), Fukazawa T (1996), Umehara H (2002), Grossmann A (2015)	24
ERBB2	6	ANKS1A	3	unspecified method	Jones RB (2006)	1
SFN	1	USP8	7	affinity chromatography technology	Benzinger A (2005)	1
PTPN1	2	CTNNB1	30	pull down	Xu G (2002)	1
ERBB2	6	CRKL	1	unspecified method	Jones RB (2006)	1
SHC1	0	HSPA8	4	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
ERBB3	3	VAV1	2	unspecified method	Jones RB (2006)	1
NCK2	2	SOS1	5	affinity chromatography technology	Braverman LE (1999)	1
HSP90AB1	2	STUB1	4	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
GRB2	2	CTTN	1	affinity chromatography technology	Brehme M (2009)	1
HSP90AB1	2	HSPA1A	0	biochemical, affinity chromatography technology	Havugimana PC (2012), Falsone SF (2005)	2
LYN	2	SHC1	0	affinity chromatography technology	Ptasznik A (1995)	1
SRC	2	STAT3	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down	Cao X (1996), Cao X (1996), Yin N (2004), Yin N (2004), Jaganathan S (2011), Jaganathan S (2011), Gray MJ (2005), Schreiner SJ (2002)	8
HDAC6	0	JAK2	1	affinity chromatography technology	M L (2016)	1
GRB2	2	PIK3R3	0	affinity chromatography technology	Bisson N (2011)	1
GRB2	2	GAB1	3	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, far western blotting, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Oneyama C (2002), Lewitzky M (2001), Lewitzky M (2001), Lewitzky M (2001), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Bandyopadhyay S (2010), Ingham RJ (1998), Brehme M (2009), Fixman ED (1997), Bisson N (2011), Huttlin EL (2017), Kapoor GS (2010), Lehr S (1999)	15
CBLB	3	CRKL	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Elly C (1999), Elly C (1999), Grossmann A (2015)	3
ERBB2	6	PIK3R1	6	affinity chromatography technology, unspecified method	Crovello CS (1998), Jones RB (2006)	2
STAT3	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Gunaje JJ (2001), M L (2016)	2
HDAC6	0	HSPA8	4	affinity chromatography technology, affinity chromatography technology	New M (2013), Watson GW (2016)	2
CAMLG	0	EGFR	5	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tran DD (2003), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
EGFR	5	PTPN12	2	protein complementation assay, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Deribe YL (2009), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Yao Z (2017)	5
GRB2	2	SOS1	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Liu SK (1998), Oneyama C (2002), Puil L (1994), Robinson A (1996), Li N (1993), Wong A (2002), Wong A (2002), Reif K (1994), DAngelo G (1999), Nel AE (1995), Pandey P (1995), Buday L (1994), Tong XK (2000), Park RK (1999), Okada S (1996), Okada S (1996), Okada S (1996), Germani A (1999), Park RK (1999), Chin H (1997), Saci A (2002), Sastry L (1997), Spivak-Kroizman T (1994), Ingham RJ (1996), Wang Y (1999), Chu J (1998), Brehme M (2009), Houtman JC (2006), Lao DH (2006), Bisson N (2011), Wang J (2011), Ng MY (2017), Huttlin EL (2017), Kapoor GS (2010), Saito T (2004), Klint P (1995)	37
CBL	7	CSK	3	affinity chromatography technology, affinity chromatography technology	Sanjay A (2001), Brehme M (2009)	2
CAV2	0	SRC	2	pull down	Lee H (2002)	1
PTPN6	0	CAV1	0	affinity chromatography technology	Caselli A (2002)	1
YWHAZ	1	USP8	7	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Jin J (2004)	2
NCK1	0	UBASH3B	4	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
HDAC6	0	STAT3	0	affinity chromatography technology, affinity chromatography technology, imaging technique	M L (2016), M L (2016), M L (2016)	3
EGFR	5	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marques MM (1999), Li J (2013), Li J (2013), Sharif A (2009)	4
HDAC6	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Kekatpure VD (2009), Rao R (2008), Bali P (2005), Kovacs JJ (2005), New M (2013), Rao R (2012), Kovacs JJ (2005)	7
SH3KBP1	1	PDCD6IP	3	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down	Schmidt MH (2004), Rauch S (2011), Havrylov S (2009), Usami Y (2007), Ichioka F (2007), Ichioka F (2007), Schmidt MH (2005), Carlton JG (2008), Chen B (2000)	9
ERRFI1	1	SHC1	0	affinity chromatography technology, affinity chromatography technology	Li J (2013), Li J (2013)	2
HDAC6	0	HSPA4	3	affinity chromatography technology	New M (2013)	1
ERRFI1	1	HSPA1A	0	affinity chromatography technology	Li J (2013)	1
ERBB3	3	HSPA8	4	affinity chromatography technology	Li J (2013)	1
GRB2	2	HGS	5	affinity chromatography technology	Bisson N (2011)	1
CDH1	4	NCK2	2	bioid	Guo Z (2014)	1
EGFR	5	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Olayioye MA (1999), Xia L (2002), Andl CD (2004), Foerster S (2013), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	8
EPS8	1	CBL	7	two hybrid, affinity chromatography technology	Grossmann A (2015), Jeganathan N (2016)	2
NCK1	0	PIK3R3	0	two hybrid	Grossmann A (2015)	1
UBASH3B	4	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), Li J (2013), Li J (2013)	3
EGFR	5	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, x-ray crystallography, pull down, x-ray crystallography, enzymatic study, enzymatic study, pull down, fluorescent resonance energy transfe, enzymatic study, pull down, protein complementation assay, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, biochemical, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Odintsova E (2003), Guo HB (2009), Tong J (2008), Zhang X (2006), Foerster S (2013), Puliyappadamba VT (2013), Tong J (2014), Crossland S (1996), Garrett TP (2002), Ogiso H (2002), Ferguson KM (2003), Bessman NJ (2014), Bessman NJ (2014), Nishibe S (1989), Breindel JL (2013), Hwang Y (2011), Petras M (2013), Yang RY (2010), Yang RY (2010), Yang RY (2010), Yao Z (2017), Fan QW (2013), Li L (2014), Li L (2014), Fernandes H (2001), Fernandes H (2001), Cochet C (1984), Honegger AM (1989), Red Brewer M (2009), Groenen LC (1997)	30
CBL	7	PIK3R3	0	two hybrid, two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015), Grossmann A (2015)	3
PIK3R2	3	CRK	0	affinity chromatography technology, affinity chromatography technology, two hybrid	Brehme M (2009), Brehme M (2009), Grossmann A (2015)	3
PLCG2	11	LYN	2	affinity chromatography technology, pull down, affinity chromatography technology	Pleiman CM (1993), Pleiman CM (1993), Guo B (2000)	3
PTPN1	2	STAT5A	4	unspecified method	Espanel X (2002)	1
CRK	0	SRC	2	affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Garcia-Guzman M (2000)	2
GRB2	2	CRKL	1	affinity chromatography technology	Park RK (1999)	1
HDAC6	0	ERBB3	3	protein complementation assay	Deribe YL (2009)	1
GRB2	2	CSK	3	affinity chromatography technology	Bisson N (2011)	1
EPS15	1	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	van Delft S (1997), Sigismund S (2005), Bertelsen V (2011), Parachoniak CA (2009), Parachoniak CA (2009), Hoeller D (2006)	6
CRK	0	ZAP70	5	pull down	Gelkop S (1999)	1
PIK3R1	6	ZAP70	5	affinity chromatography technology	Moon KD (2005)	1
EPS15	1	USP8	7	affinity chromatography technology, enzymatic study	Mizuno E (2006), Mizuno E (2006)	2