PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
MYO5C	8	LIMA1	4	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
TP53	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Wang C (2003), Akakura S (2001), Peng Y (2001), Nagata Y (1999), Wang J (2011), Burch L (2004), Taipale M (2012), Fogeron ML (2013), Walerych D (2004)	9
MYH9	19	PPP1CB	9	affinity chromatography technology	Hein MY (2015)	1
MYO19	0	CAPZA2	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
CDKN1A	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology	Ono T (2000), McKenzie PP (2003), McKenzie PP (2003), Law BK (2002), Harper JW (1993), Harper JW (1993), Yam CH (1999), Selma Dagtas A (2010), Naderi S (2005), Varshochi R (2005), Jeong JH (2010), Hsu SP (2008), Scholz A (2003), Peiretti A (2003), Peiretti A (2003), Derjuga A (2001), Kim YB (2000), Park US (2000), Kim WH (2000), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Bendjennat M (2003), Zheleva DI (2002), Mandal M (1998), Bao GC (2006), Mattock H (2001), Chen Z (2002), Chen J (1996), Chen J (1996), Levkau B (1998), Levkau B (1998), Ramachandran N (2004), Lacy ER (2005), Akagi M (1996), Zhao J (1998), Zhang Y (1999), Poon RY (1998), Gorospe M (1996), Varjosalo M (2013), Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Hall JR (2014), Hein MY (2015), Hein MY (2015), Chen TC (2014), Hukkelhoven E (2012), Huttlin EL (2017), Roessig L (2001)	51
MYO19	0	FLNA	10	affinity chromatography technology	Hein MY (2015)	1
MDM2	2	DAPK3	5	unspecified method, enzymatic study, imaging technique	Burch LR (2004), Burch LR (2004), Felten A (2012)	3
MYH9	19	LIMA1	4	affinity chromatography technology	Hein MY (2015)	1
CDK2	0	SYNPO	5	affinity chromatography technology	Hein MY (2015)	1
SYNPO	5	CAPZA2	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
CNTRL	5	DAPK3	5	bioid	Gupta GD (2015)	1
AATF	0	TSG101	1	imaging technique, imaging technique	Felten A (2012), Felten A (2012)	2
FLNA	10	MYH9	19	biochemical, affinity chromatography technology	Havugimana PC (2012), Hein MY (2015)	2
LIMA1	4	IQGAP1	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
NEDD4L	3	ULK1	8	affinity chromatography technology, affinity chromatography technology, enzymatic study	Nazio F (2016), Nazio F (2016), Nazio F (2016)	3
TP53	0	CDC14A	4	two hybrid, affinity chromatography technology, pull down	Li L (2000), Li L (2000), Li L (2000)	3
AR	3	DAPK3	5	imaging technique, imaging technique	Felten A (2012), Felten A (2012)	2
CNTRL	5	CEP170	4	bioid	Gupta GD (2015)	1
LIMA1	4	FLNA	10	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
CDK2	0	RPL34	2	affinity chromatography technology	Neganova I (2011)	1
CHEK2	2	TP53	0	affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Louria-Hayon I (2003), Shieh SY (2000), Bjorling-Poulsen M (2005), Hirao A (2000), Adams CJ (2008)	5
CDK2	0	PPP1CB	9	affinity chromatography technology	Hein MY (2015)	1
DAXX	5	TP53	0	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, unspecified method	Tang J (2006), Kim EJ (2003), Kim EJ (2003), Kim EJ (2003), Ohiro Y (2003), Ohiro Y (2003), Ohiro Y (2003), Ohiro Y (2003), Wethkamp N (2011), Zhao LY (2004), Zhao LY (2004), Zhao LY (2004), Gostissa M (2004), Gostissa M (2004), Gostissa M (2004), Gostissa M (2004), Gostissa M (2004), Zhao LY (2004), Zhao LY (2004), Zhang H (2013), Zhang H (2013), Chen TC (2014), Li Z (2017)	23
AR	3	TSG101	1	two hybrid, imaging technique, imaging technique	Hittelman AB (1999), Felten A (2012), Felten A (2012)	3
MYO19	0	SYNPO	5	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
KIF2B	2	CEP170	4	affinity chromatography technology	Huttlin EL (2017)	1
CEP128	1	CEP170	4	bioid	Gupta GD (2015)	1
TP53	0	FLNA	10	affinity chromatography technology	Horikawa I (2014)	1
PPP1CB	9	CAPZA2	1	affinity chromatography technology	Hein MY (2015)	1
MYO19	0	MYO5C	8	affinity chromatography technology	Hein MY (2015)	1
AK3	1	DAPK3	5	two hybrid	Wang J (2011)	1
CEP104	4	DAPK3	5	bioid	Gupta GD (2015)	1
RAD21	3	DAPK3	5	two hybrid, affinity chromatography technology	Panigrahi AK (2011), Panigrahi AK (2011)	2
MYO18A	7	SYNPO	5	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
GPS2	0	TP53	0	affinity chromatography technology, pull down	Peng YC (2001), Peng YC (2001)	2
MYO18A	7	MYH9	19	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
MYH9	19	PAWR	2	affinity chromatography technology	Hein MY (2015)	1
FLNA	10	DAPK3	5	affinity chromatography technology	Hein MY (2015)	1
CEP128	1	NINL	1	bioid	Gupta GD (2015)	1
TSG101	1	IQGAP1	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Morita E (2007), Morita E (2007), Morita E (2007)	3
CDK2	0	LIMA1	4	affinity chromatography technology	Hein MY (2015)	1
IQGAP1	1	MYO5C	8	affinity chromatography technology	Hein MY (2015)	1
TSG101	1	MDM2	2	affinity chromatography technology, affinity chromatography technology	Li L (2001), Cheng TH (2007)	2
MYO19	0	DAPK3	5	affinity chromatography technology	Hein MY (2015)	1
CDK2	0	MYH9	19	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Hein MY (2015)	2
PCM1	5	CEP170	4	affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
CEP128	1	TP53	0	bioid	Gupta GD (2015)	1
CDKN1A	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe, affinity chromatography technology, imaging technique	Zhang Z (2004), Zhang Z (2004), Zhang Z (2004), Jin Y (2003), Jin Y (2003), Wang B (2010), Xu H (2010), Xu H (2010), Frum R (2007), Chen TC (2014)	10
CEP128	1	PCM1	5	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
NINL	1	TP53	0	bioid	Gupta GD (2015)	1
MYO18A	7	MYO5C	8	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
DAPK3	5	CDKN1A	1	unspecified method, enzymatic study	Burch LR (2004), Burch LR (2004)	2
CAPZA2	1	MYO5C	8	biochemical, affinity chromatography technology, affinity chromatography technology	Wan C (2015), Hein MY (2015), Hein MY (2015)	3
MYO19	0	MYH9	19	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
IQGAP1	1	CAPZA2	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
MYO5C	8	FLNA	10	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
MEAF6	0	DAPK3	5	affinity chromatography technology	Huttlin EL (2017)	1
PAWR	2	DAPK3	5	affinity chromatography technology, two hybrid, enzymatic study, enzymatic study	Kawai T (2003), Kawai T (2003), Kawai T (2003), Burch LR (2004)	4
TP53	0	LIMA1	4	affinity chromatography technology	Horikawa I (2014)	1
TSG101	1	TP53	0	affinity chromatography technology, affinity chromatography technology	Li L (2001), Li L (2001)	2
MYO18A	7	LIMA1	4	affinity chromatography technology	Hein MY (2015)	1
DAPK3	5	PRKCZ	5	pull down	Cariou B (2002)	1
CDK2	0	TP53	0	enzymatic study, enzymatic study, imaging technique	Luciani MG (2000), Tsai CH (2009), Chen TC (2014)	3
SYNPO	5	FLNA	10	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
HSP90AA1	7	DAPK3	5	affinity chromatography technology	Taipale M (2012)	1
CEP128	1	PAWR	2	bioid	Gupta GD (2015)	1
DAXX	5	TSG101	1	affinity chromatography technology, affinity chromatography technology	Muromoto R (2004), Muromoto R (2004)	2
MYO19	0	LIMA1	4	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
MYO19	0	IQGAP1	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
NINL	1	CEP170	4	bioid	Gupta GD (2015)	1
NINL	1	DAPK3	5	bioid	Gupta GD (2015)	1
CHEK2	2	MDM2	2	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study	Pereg Y (2006), Kass EM (2009), Kass EM (2009), Bjorling-Poulsen M (2005), Bjorling-Poulsen M (2005), Bjorling-Poulsen M (2005), Bjorling-Poulsen M (2005)	7
MYH9	19	SYNPO	5	affinity chromatography technology	Hein MY (2015)	1
CDK2	0	IQGAP1	1	affinity chromatography technology	Neganova I (2011)	1
UBE2D3	1	DAPK3	5	affinity chromatography technology	Ohbayashi N (2008)	1
NINL	1	GPS2	0	bioid	Gupta GD (2015)	1
MYO18A	7	DAPK3	5	affinity chromatography technology	Hein MY (2015)	1
CAPZA2	1	DAPK3	5	affinity chromatography technology	Hein MY (2015)	1
PPP1CB	9	MYO19	0	affinity chromatography technology	Hein MY (2015)	1
TSG101	1	DAPK3	5	imaging technique	Felten A (2012)	1
RAD21	3	HSP90AA1	7	affinity chromatography technology	Panigrahi AK (2011)	1
MYO5C	8	SYNPO	5	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
TP53	0	IQGAP1	1	affinity chromatography technology	Fogeron ML (2013)	1
HSP90AA1	7	MYH9	19	affinity chromatography technology	Falsone SF (2005)	1
IQGAP1	1	SYNPO	5	affinity chromatography technology	Hein MY (2015)	1
IQGAP1	1	PPP1CB	9	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
LIMA1	4	SYNPO	5	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
PCM1	5	DAPK3	5	bioid	Gupta GD (2015)	1
NINL	1	PCM1	5	bioid	Gupta GD (2015)	1
AATF	0	NEDD4L	3	two hybrid	Wang J (2011)	1
CNTRL	5	PCM1	5	bioid	Gupta GD (2015)	1
PRKCZ	5	HSP90AA1	7	two hybrid, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Taipale M (2012), Taipale M (2012)	3
DAXX	5	AR	3	two hybrid, pull down, affinity chromatography technology, pull down	Lin DY (2004), Lin DY (2004), Lin DY (2004), Sun S (2016)	4
CEP128	1	DAPK3	5	bioid	Gupta GD (2015)	1
AATF	0	DAPK3	5	imaging technique	Felten A (2012)	1
TP53	0	CDKN1A	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique	Tian H (2002), Vinayagam A (2011), Kinyamu HK (2003), Giono LE (2007), Chen TC (2014)	5
MDM2	2	UBE2D3	1	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Yadavilli S (2009), Nie J (2010), Minsky N (2004), Wang X (2011), Sionov RV (2001), Oh W (2010), Zhu Y (2009), Latini P (2011), Jung CR (2010), David Y (2011), Ye B (2013), Cheng Q (2014), Saville MK (2004), Yamauchi T (2014), Jin M (2017)	15
CEP170	4	DAPK3	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SYNPO	5	DAPK3	5	affinity chromatography technology	Hein MY (2015)	1
GPS2	0	DAPK3	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GRB14	1	PRKCZ	5	affinity chromatography technology	Cariou B (2002)	1
HSP90AA1	7	FLNA	10	affinity chromatography technology	Falsone SF (2005)	1
AATF	0	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	De Nicola F (2007), De Nicola F (2007), De Nicola F (2014)	3
ULK1	8	DAPK3	5	affinity chromatography technology	Tang HW (2011)	1
PRKCZ	5	PAWR	2	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Diaz-Meco MT (1996), Diaz-Meco MT (1996), Diaz-Meco MT (1996), Diaz-Meco MT (1996), Diaz-Meco MT (1996), Chang S (2002)	6
DAPK3	5	DAPK3	5	enzymatic study, enzymatic study, enzymatic study	Burch LR (2004), Felten A (2012), Sawasaki T (2008)	3
MYH9	19	CAPZA2	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
DAPK3	5	RPL34	2	two hybrid	Wang J (2011)	1
IQGAP1	1	MYO18A	7	affinity chromatography technology	Hein MY (2015)	1
MDM2	2	HSP90AA1	7	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, biochemical, unspecified method, affinity chromatography technology	Lu TL (2010), Burch L (2004), Burch L (2004), Burch L (2004), Burch L (2004), Burch LR (2004), Okoro DR (2013)	7
KLHDC3	1	DAPK3	5	affinity chromatography technology	Huttlin EL (2017)	1
LIMA1	4	DAPK3	5	affinity chromatography technology	Hein MY (2015)	1
CAPZA2	1	LIMA1	4	affinity chromatography technology	Hein MY (2015)	1
AR	3	AATF	0	imaging technique, imaging technique	Felten A (2012), Felten A (2012)	2
DAPK3	5	TP53	0	enzymatic study	Burch LR (2004)	1
CEP104	4	CEP170	4	bioid	Gupta GD (2015)	1
HSP90AA1	7	AR	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Veldscholte J (1992), Nemoto T (1992), Zoubeidi A (2007), DaSilva J (2009), Chymkowitch P (2011), Gibbs A (2009), Wolf SS (2007), Luo J (2015), Kwegyir-Afful AK (2015), Ni L (2010), McClurg UL (2016)	11
KIF2B	2	DAPK3	5	affinity chromatography technology	Huttlin EL (2017)	1
DAPK3	5	CHEK2	2	enzymatic study	Burch LR (2004)	1
DAXX	5	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method	Ivanchuk SM (2008), Ivanchuk SM (2008), Tang J (2006), Tang J (2006), Tang J (2006), Song MS (2008), Zhao LY (2004), Tang J (2013), Tang J (2013), Zhao LY (2004), Zhang H (2013), Zhang H (2013), Li Z (2017)	13
CDK2	0	DAPK3	5	affinity chromatography technology	Hein MY (2015)	1
DAPK3	5	DAXX	5	affinity chromatography technology, affinity chromatography technology	Kawai T (2003), Kawai T (2003)	2
TNFRSF8	2	DAPK3	5	affinity chromatography technology	Huttlin EL (2017)	1
NEDD4L	3	DAPK3	5	enzymatic study	Persaud A (2009)	1
AR	3	TP53	0	genetic interference	Shenk JL (2001)	1
CEP128	1	CNTRL	5	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
CHEK2	2	CDC14A	4	genetic interference	Srivas R (2016)	1
MYO18A	7	CAPZA2	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
UBE2D3	1	NEDD4L	3	pull down, pull down, pull down	Maspero E (2013), Todaro DR (2017), Wang Z (2016)	3
PPP1CB	9	LIMA1	4	affinity chromatography technology	Hein MY (2015)	1
PPP1CB	9	FLNA	10	affinity chromatography technology	Hein MY (2015)	1
MYO5C	8	DAPK3	5	affinity chromatography technology	Hein MY (2015)	1
SYNPO	5	PPP1CB	9	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
DAPK3	5	TCP10L	0	two hybrid	Wang J (2011)	1
MYH9	19	IQGAP1	1	affinity chromatography technology	Hein MY (2015)	1
FLNA	10	CAPZA2	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
MYH9	19	MYO5C	8	affinity chromatography technology	Hein MY (2015)	1
MYH9	19	DAPK3	5	affinity chromatography technology	Hein MY (2015)	1
AATF	0	CHEK2	2	pull down, affinity chromatography technology	Bruno T (2006), Bruno T (2006)	2
CDK2	0	FLNA	10	affinity chromatography technology	Neganova I (2011)	1
AR	3	MDM2	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zoubeidi A (2007), Gaughan L (2005), Gaughan L (2005), Chymkowitch P (2011), Chymkowitch P (2011), Liu T (2012), Liu T (2012), Deep G (2008), Deep G (2008), Lin HK (2002), Lin HK (2002), Zhang A (2015), Kwegyir-Afful AK (2015), McClurg UL (2016), McClurg UL (2016), Liao Y (2017), Steely AM (2017), Zhai W (2016)	18
PPP1CB	9	MYO5C	8	affinity chromatography technology	Hein MY (2015)	1
DAPK3	5	GRB14	1	pull down	Cariou B (2002)	1
MYO18A	7	FLNA	10	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
AR	3	FLNA	10	two hybrid	Loy CJ (2003)	1
CDC14A	4	DAPK3	5	bioid	St-Denis N (2016)	1
IQGAP1	1	FLNA	10	affinity chromatography technology	Hein MY (2015)	1
TSG101	1	CDKN1A	1	two hybrid, affinity chromatography technology	Oh H (2002), Oh H (2002)	2
HSP90AA1	7	CDKN1A	1	affinity chromatography technology	Jascur T (2005)	1
CDK2	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Varjosalo M (2013)	2
MYO18A	7	MYO19	0	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
IQGAP1	1	DAPK3	5	affinity chromatography technology	Hein MY (2015)	1
AATF	0	PAWR	2	affinity chromatography technology, affinity chromatography technology	Guo Q (2004), Guo Q (2004)	2
CDK2	0	MYO18A	7	affinity chromatography technology	Hein MY (2015)	1
MYO18A	7	PPP1CB	9	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
PPP1CB	9	DAPK3	5	affinity chromatography technology	Hein MY (2015)	1
CEP104	4	PCM1	5	bioid	Gupta GD (2015)	1
TP53	0	MYH9	19	affinity chromatography technology	Horikawa I (2014)	1