Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CYP51A1 1595 ITRACONAZOLE CHEMBL22587 inhibitor DrugBank 16964330, 11752352, 10608831
CYP51A1 1595 TIOCONAZOLE CHEMBL1200438 inhibitor DrugBank 15625110, 17139284, 17016423, 10592235
CYP51A1 1595 AZALANSTAT CHEMBL70611 inhibitor GuideToPharmacologyInteractions
CYP51A1 1595 FLUCONAZOLE CHEMBL106 NCI 12116245
CYP51A1 1595 METRONIDAZOLE CHEMBL137 DrugBank 17194716
CYP51A1 1595 RIFAMPICIN CHEMBL374478 DrugBank 17194716

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
CYP51A1 rs7793861 G glibenclamide efficacy yes No allele was given for the association, so the minor allele from dbSNP at this location was used. Response to treatment was measured as reduction of HbA1c below 6.5% at 1-year of treatment. Allele G is associated with increased response to glibenclamide in people with as compared to allele C. 27403931 1448123507